JP2007517895A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2007517895A5 JP2007517895A5 JP2006549475A JP2006549475A JP2007517895A5 JP 2007517895 A5 JP2007517895 A5 JP 2007517895A5 JP 2006549475 A JP2006549475 A JP 2006549475A JP 2006549475 A JP2006549475 A JP 2006549475A JP 2007517895 A5 JP2007517895 A5 JP 2007517895A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- substituted
- membered
- heteroaryl
- ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CCN(CC)CCC* Chemical compound CCN(CC)CCC* 0.000 description 15
- CCSKCDULCFGGTP-UHFFFAOYSA-N CCN(CCc1ccccn1)S(C)=O Chemical compound CCN(CCc1ccccn1)S(C)=O CCSKCDULCFGGTP-UHFFFAOYSA-N 0.000 description 1
- ODHMYZBQXOCZDJ-UHFFFAOYSA-N CCN(Cc1ncccc1)S(C)(=O)=O Chemical compound CCN(Cc1ncccc1)S(C)(=O)=O ODHMYZBQXOCZDJ-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53489804P | 2004-01-08 | 2004-01-08 | |
| PCT/US2005/000663 WO2005066139A2 (en) | 2004-01-08 | 2005-01-10 | 2-(amino-substituted)-4-aryl pyramidines and related compounds useful for treating inflammatory diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007517895A JP2007517895A (ja) | 2007-07-05 |
| JP2007517895A5 true JP2007517895A5 (enExample) | 2008-01-24 |
Family
ID=34749013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006549475A Pending JP2007517895A (ja) | 2004-01-08 | 2005-01-10 | 炎症疾患を処置するのに有用な２−（アミノ置換）−４−アリールピリミジンおよび関連化合物 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US7732444B2 (enExample) |
| EP (2) | EP2123647A1 (enExample) |
| JP (1) | JP2007517895A (enExample) |
| AR (1) | AR047185A1 (enExample) |
| AT (1) | ATE437861T1 (enExample) |
| AU (1) | AU2005204060A1 (enExample) |
| CA (1) | CA2559888A1 (enExample) |
| CY (1) | CY1109529T1 (enExample) |
| DE (1) | DE602005015677D1 (enExample) |
| DK (1) | DK1701944T3 (enExample) |
| ES (1) | ES2330863T3 (enExample) |
| HR (1) | HRP20090572T1 (enExample) |
| PL (1) | PL1701944T3 (enExample) |
| PT (1) | PT1701944E (enExample) |
| RS (1) | RS51091B (enExample) |
| SI (1) | SI1701944T1 (enExample) |
| TW (1) | TW200533357A (enExample) |
| WO (1) | WO2005066139A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200533357A (en) * | 2004-01-08 | 2005-10-16 | Millennium Pharm Inc | 2-(amino-substituted)-4-aryl pyrimidines and related compounds useful for treating inflammatory diseases |
| WO2005095386A1 (en) * | 2004-03-30 | 2005-10-13 | Chiron Corporation | Substituted thiophene derivatives as anti-cancer agents |
| GB0428250D0 (en) * | 2004-12-23 | 2005-01-26 | Novartis Ag | Organic compounds |
| JP2009521488A (ja) * | 2005-12-21 | 2009-06-04 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｐｋｃ−シータのインヒビターとして有益なピリミジン誘導体 |
| WO2007107543A1 (en) * | 2006-03-22 | 2007-09-27 | Janssen Pharmaceutica N.V. | Inhibitors of the interaction between mdm2 and p53 |
| AU2008236679B2 (en) * | 2007-04-03 | 2013-11-28 | Fmc Corporation | Substituted benzene fungicides |
| HUE024877T2 (en) * | 2007-10-30 | 2016-02-29 | Genentech Inc | Antibody purification by cation exchange chromatography |
| JPWO2009107391A1 (ja) | 2008-02-27 | 2011-06-30 | 武田薬品工業株式会社 | ６員芳香環含有化合物 |
| EP2169665B1 (en) | 2008-09-25 | 2018-05-02 | LG Electronics Inc. | A method and an apparatus for processing a signal |
| EP2599494A1 (en) * | 2010-01-11 | 2013-06-05 | Healor Ltd. | PKC inhibitors for the treatment of inflammatory disease or disorder |
| US20130109019A1 (en) * | 2010-07-02 | 2013-05-02 | Adrian E. Murillo | Hapten conjugates for target detection |
| US9133187B2 (en) | 2011-02-28 | 2015-09-15 | Array Biopharma Inc. | Serine/threonine kinase inhibitors |
| ES2552989T3 (es) | 2011-08-04 | 2015-12-03 | Array Biopharma, Inc. | Compuestos de quinazolina como inhibidores de la cinasa de serina / treonina |
| PE20150666A1 (es) | 2012-03-01 | 2015-05-06 | Array Biopharma Inc | Inhibidores de serina/treonina cinasa |
| SG11201406584TA (en) | 2012-04-24 | 2014-11-27 | Vertex Pharma | Dna-pk inhibitors |
| CA2882750A1 (en) | 2012-08-27 | 2014-03-06 | Jim Blake | Serine/threonine kinase inhibitors for the treatment of hyperproliferative|diseases |
| RS62649B1 (sr) | 2013-03-12 | 2021-12-31 | Vertex Pharma | Inhibitori dnk-pk |
| CA2923765C (en) | 2013-09-18 | 2021-06-29 | University Of Canberra | Stem cell modulation ii |
| KR102411227B1 (ko) | 2013-10-17 | 2022-06-21 | 버텍스 파마슈티칼스 인코포레이티드 | Dna-pk 억제제로서 (s)-n-메틸-8-(1-((2'-메틸-[4,5'-비피리미딘]-6-일)아미노)프로판-2-일)퀴놀린-4-카복스아미드 및 이의 듀테로화된 유도체의 공결정 |
| AU2015309686B2 (en) | 2014-08-25 | 2020-05-14 | Epiaxis Therapeutics Pty Ltd | Compositions for modulating cancer stem cells and uses therefor |
| MX394860B (es) | 2016-09-27 | 2025-03-24 | Vertex Pharma | Metodo para tratar cancer usando una combinacion de agentes que dañan adn e inhibidores de proteina cinasa dependiente de adn (adn-pk). |
| WO2023104744A1 (en) | 2021-12-06 | 2023-06-15 | Helmholtz-Zentrum Dresden-Rossendorf E.V. | 3-((3-([1,1'-biphenyl]-3-ylmethoxy)phenoxy)methyl)benzonitrile derivatives and the use thereof |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5698697A (en) | 1995-07-19 | 1997-12-16 | Mitsubishi Chemical Corporation | 2-cyanopiperazine and method of producing the same |
| JP2001526230A (ja) * | 1997-12-19 | 2001-12-18 | スミスクライン・ビーチャム・コーポレイション | ヘテロアリール置換イミダゾール化合物、その医薬組成物および使用 |
| ATE245641T1 (de) | 1998-02-17 | 2003-08-15 | Tularik Inc | Antivirale pyrimidinderivate |
| DE69919707T2 (de) | 1998-06-19 | 2005-09-01 | Chiron Corp., Emeryville | Glycogen synthase kinase 3 inhibitoren |
| US7045519B2 (en) | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| CZ20012350A3 (cs) | 1998-12-24 | 2001-09-12 | Aventis Pharmaceuticals Products Inc. | Substituované (aminoiminomethyl nebo aminomethyl) benzoheteroarylové sloučeniny |
| US6492516B1 (en) | 1999-05-14 | 2002-12-10 | Merck & Co., Inc. | Compounds having cytokine inhibitory activity |
| WO2001000214A1 (en) * | 1999-06-30 | 2001-01-04 | Merck & Co., Inc. | Src kinase inhibitor compounds |
| DE60039616D1 (de) | 1999-08-13 | 2008-09-04 | Vertex Pharma | INHIBITOREN DER c-JUN N-TERMINALEN KINASE (JNK) UND ANDERE PROTEIN-KINASEN |
| GB0003224D0 (en) * | 2000-02-11 | 2000-04-05 | Glaxo Group Ltd | Chemical compounds |
| US6869956B2 (en) | 2000-10-03 | 2005-03-22 | Bristol-Myers Squibb Company | Methods of treating inflammatory and immune diseases using inhibitors of IκB kinase (IKK) |
| EP1326865B1 (en) | 2000-10-12 | 2009-05-06 | Merck & Co., Inc. | Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors |
| MXPA03008888A (es) * | 2001-03-29 | 2005-03-07 | Vertex Pharma | Inhibidores de n-terminal c-jun cinasas (jnk) y otras proteinas cinasas. |
| DE60214701T2 (de) * | 2001-04-13 | 2007-09-13 | Vertex Pharmaceuticals Inc., Cambridge | Inhibitoren von c-jun-n-terminalen-kinasen (jnk) und anderen proteinkinasen |
| GB0112803D0 (en) | 2001-05-25 | 2001-07-18 | Glaxo Group Ltd | Pyrimidine derivatives |
| MXPA04004166A (es) | 2001-11-07 | 2004-07-08 | Hoffmann La Roche | Aminopirimidinas y piridinas. |
| TWI319387B (en) * | 2002-04-05 | 2010-01-11 | Astrazeneca Ab | Benzamide derivatives |
| WO2003106451A1 (en) * | 2002-06-14 | 2003-12-24 | Altana Pharma Ag | Substituted diaminopyrimidines |
| TW200510311A (en) | 2002-12-23 | 2005-03-16 | Millennium Pharm Inc | CCr8 inhibitors |
| EP1590334B1 (en) | 2003-01-30 | 2009-08-19 | Boehringer Ingelheim Pharmaceuticals Inc. | 2,4-diaminopyrimidine derivatives useful as inhibitors of pkc-theta |
| AU2004229392A1 (en) | 2003-04-09 | 2004-10-28 | Exelixis, Inc. | Tie-2 modulators and methods of use |
| AR044519A1 (es) * | 2003-05-02 | 2005-09-14 | Novartis Ag | Derivados de piridin-tiazol amina y de pirimidin-tiazol amina |
| US7459460B2 (en) | 2003-05-28 | 2008-12-02 | Bristol-Myers Squibb Company | Trisubstituted heteroaromatic compounds as calcium sensing receptor modulators |
| TW200533357A (en) * | 2004-01-08 | 2005-10-16 | Millennium Pharm Inc | 2-(amino-substituted)-4-aryl pyrimidines and related compounds useful for treating inflammatory diseases |
| KR20070003934A (ko) * | 2004-03-05 | 2007-01-05 | 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 | 치료제의 환자 내약성을 예측하기 위한 시험관 내 테스트시스템 |
| WO2005095386A1 (en) * | 2004-03-30 | 2005-10-13 | Chiron Corporation | Substituted thiophene derivatives as anti-cancer agents |
| EP1751136B1 (en) | 2004-05-07 | 2014-07-02 | Amgen Inc. | Nitrogenated heterocyclic derivatives as protein kinase modulators and use for the treatment of angiogenesis and cancer |
| MXPA06014247A (es) | 2004-06-10 | 2007-03-12 | Irm Llc | Compuestos y composiciones como inhibidores de la proteina quinasa. |
| EP1809290A2 (en) * | 2004-11-03 | 2007-07-25 | Vertex Pharmaceuticals Incorporated | Pyrimidine derivatives as ion channel modulators and methods of use |
| TWI359810B (en) | 2004-11-04 | 2012-03-11 | Mitsubishi Tanabe Pharma Corp | Carboxylic acid derivative containing thiazole rin |
| AU2005316312B2 (en) | 2004-12-17 | 2009-10-22 | Amgen, Inc. | Aminopyrimidine compounds and methods of use |
| US20060178388A1 (en) | 2005-02-04 | 2006-08-10 | Wrobleski Stephen T | Phenyl-substituted pyrimidine compounds useful as kinase inhibitors |
| DE102005034821A1 (de) * | 2005-07-26 | 2007-02-08 | Fleissner Gmbh | Voluminöse Faserlaminate und ihre Herstellung |
| TWM293131U (en) * | 2006-01-10 | 2006-07-01 | Shuen Tai Prec Entpr Co Ltd | Handheld power hammer |
-
2005
- 2005-01-07 TW TW094100533A patent/TW200533357A/zh unknown
- 2005-01-10 HR HR20090572T patent/HRP20090572T1/hr unknown
- 2005-01-10 EP EP09009692A patent/EP2123647A1/en not_active Withdrawn
- 2005-01-10 AT AT05726205T patent/ATE437861T1/de active
- 2005-01-10 PL PL05726205T patent/PL1701944T3/pl unknown
- 2005-01-10 SI SI200530816T patent/SI1701944T1/sl unknown
- 2005-01-10 JP JP2006549475A patent/JP2007517895A/ja active Pending
- 2005-01-10 US US11/032,299 patent/US7732444B2/en not_active Expired - Fee Related
- 2005-01-10 ES ES05726205T patent/ES2330863T3/es not_active Expired - Lifetime
- 2005-01-10 DE DE602005015677T patent/DE602005015677D1/de not_active Expired - Lifetime
- 2005-01-10 PT PT05726205T patent/PT1701944E/pt unknown
- 2005-01-10 AR ARP050100080A patent/AR047185A1/es unknown
- 2005-01-10 WO PCT/US2005/000663 patent/WO2005066139A2/en not_active Ceased
- 2005-01-10 RS RSP-2009/0466A patent/RS51091B/sr unknown
- 2005-01-10 CA CA002559888A patent/CA2559888A1/en not_active Abandoned
- 2005-01-10 DK DK05726205T patent/DK1701944T3/da active
- 2005-01-10 EP EP05726205A patent/EP1701944B1/en not_active Expired - Lifetime
- 2005-01-10 AU AU2005204060A patent/AU2005204060A1/en not_active Abandoned
-
2009
- 2009-10-27 CY CY20091101118T patent/CY1109529T1/el unknown
-
2010
- 2010-04-26 US US12/767,139 patent/US8268822B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011510080A5 (enExample) | ||
| RU2002123350A (ru) | Дипептиднитрильные ингибиторы катепсина К | |
| JP2008530240A5 (enExample) | ||
| RU2009121775A (ru) | Пиридильное неароматическое азот-содержащее гетероцикло-1-карбоксилатное производное | |
| JP2012512886A5 (enExample) | ||
| WO2015085238A1 (en) | Inhibitors of lpxc | |
| NO20045103L (no) | Benzofuserte heteroarylamid-derivater av thienopyridiner anvendelige som terapeutiske midler, farmasoytiske blandinger omfattende de samme og fremgangsmater for deres anvendelse | |
| JP2001526276A5 (enExample) | ||
| RU2000102359A (ru) | Фармацевтическая композиция, обладающая улучшенным противораковым действием и/или сниженными побочными эффектами, содержащая противораковый агент и производное гидроксамовой кислоты | |
| JP2005501120A5 (enExample) | ||
| JP2006507326A5 (enExample) | ||
| RU2002122105A (ru) | Производное бензимидазола | |
| JP2015511638A5 (enExample) | ||
| ATE291013T1 (de) | Durch einen omega-thiarest substituierte phenyl- prostaglandin-e-derivate, verfahren zu ihrer herstellung und medikamente die diese als aktiven inhaltsstoff enthalten | |
| ES2954126T3 (es) | Derivados del pirazolo[1,5-a]pirimidina-7-amina útiles en terapia | |
| JP2007528417A5 (enExample) | ||
| KR920009796A (ko) | 3-아미도인돌릴 유도체 | |
| JP2002536329A5 (enExample) | ||
| RU2003121236A (ru) | Арилированные амиды фуран- и тиофенкарбоновых кислот с блокирующим калиевый канал действием | |
| JP2006522813A5 (enExample) | ||
| BR112015029463B1 (pt) | Bissulfato de inibidor da janus quinase (jak), seu uso e seu método de preparação, e composição farmacêutica | |
| JP2010516700A5 (enExample) | ||
| JP2023513419A5 (enExample) | ||
| JP2002537258A5 (enExample) | ||
| JP2008503533A5 (enExample) |