JP2007517016A5 - - Google Patents
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- Publication number
- JP2007517016A5 JP2007517016A5 JP2006546397A JP2006546397A JP2007517016A5 JP 2007517016 A5 JP2007517016 A5 JP 2007517016A5 JP 2006546397 A JP2006546397 A JP 2006546397A JP 2006546397 A JP2006546397 A JP 2006546397A JP 2007517016 A5 JP2007517016 A5 JP 2007517016A5
- Authority
- JP
- Japan
- Prior art keywords
- drug
- solid composition
- composition according
- particles
- poloxamer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000003814 drug Substances 0.000 claims 26
- 229940079593 drug Drugs 0.000 claims 25
- 239000008247 solid mixture Substances 0.000 claims 15
- 239000002245 particle Substances 0.000 claims 13
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 claims 6
- 229960000502 poloxamer Drugs 0.000 claims 6
- 229920001983 poloxamer Polymers 0.000 claims 6
- 230000009477 glass transition Effects 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 229920000642 polymer Polymers 0.000 claims 3
- 229920000623 Cellulose acetate phthalate Polymers 0.000 claims 1
- 229940081735 acetylcellulose Drugs 0.000 claims 1
- 229920002301 cellulose acetate Polymers 0.000 claims 1
- 229940081734 cellulose acetate phthalate Drugs 0.000 claims 1
- 229920003132 hydroxypropyl methylcellulose phthalate Polymers 0.000 claims 1
- 229940031704 hydroxypropyl methylcellulose phthalate Drugs 0.000 claims 1
- 229920000639 hydroxypropylmethylcellulose acetate succinate Polymers 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 230000008018 melting Effects 0.000 claims 1
- 238000002844 melting Methods 0.000 claims 1
- 125000005591 trimellitate group Chemical group 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53383603P | 2003-12-31 | 2003-12-31 | |
| PCT/IB2004/004287 WO2005065657A2 (en) | 2003-12-31 | 2004-12-20 | Solid compositions of low-solubility drugs and poloxamers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007517016A JP2007517016A (ja) | 2007-06-28 |
| JP2007517016A5 true JP2007517016A5 (https=) | 2008-02-14 |
Family
ID=34748969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006546397A Abandoned JP2007517016A (ja) | 2003-12-31 | 2004-12-20 | 低溶解性薬剤及びポロキサマーの固体組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8974823B2 (https=) |
| EP (1) | EP1701704A2 (https=) |
| JP (1) | JP2007517016A (https=) |
| BR (1) | BRPI0418330A (https=) |
| CA (1) | CA2548376A1 (https=) |
| WO (1) | WO2005065657A2 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005047561A1 (de) * | 2005-10-04 | 2007-04-05 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung |
| WO2008119659A2 (en) * | 2007-03-29 | 2008-10-09 | F. Hoffmann-La Roche Ag | Pharmaceutical composition and process |
| SI2200588T1 (sl) | 2007-09-25 | 2019-08-30 | Solubest Ltd. | Sestavki, ki obsegajo lipofilne aktivne spojine, in postopek za njihovo pripravo |
| EP2538929A4 (en) | 2010-02-25 | 2014-07-09 | Univ Johns Hopkins | DELAYED RELEASE OF THERAPIES IN A PART OF THE EYE |
| ES2801678T3 (es) * | 2010-07-12 | 2021-01-12 | Salix Pharmaceuticals Inc | Formulaciones de rifaximina y sus usos |
| US20170087134A1 (en) * | 2010-07-12 | 2017-03-30 | Salix Pharmaceuticals, Ltd | Formulations of rifaximin and uses thereof |
| US10307372B2 (en) | 2010-09-10 | 2019-06-04 | The Johns Hopkins University | Rapid diffusion of large polymeric nanoparticles in the mammalian brain |
| EP2455068A1 (en) * | 2010-11-09 | 2012-05-23 | F. Hoffmann-La Roche AG | Pharmaceutical composition for treating HCV infections |
| AR088570A1 (es) * | 2011-10-28 | 2014-06-18 | Celgene Avilomics Res Inc | Metodos para tratar una enfermedad o trastorno relacionado con la tirosina quinasa de bruton |
| JP6138904B2 (ja) | 2012-03-16 | 2017-05-31 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 活性剤の送達のための非線状マルチブロックコポリマー薬物コンジュゲート |
| US8962577B2 (en) | 2012-03-16 | 2015-02-24 | The Johns Hopkins University | Controlled release formulations for the delivery of HIF-1 inhibitors |
| US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| NZ742005A (en) * | 2012-05-03 | 2019-04-26 | Kala Pharmaceuticals Inc | Pharmaceutical nanoparticles showing improved mucosal transport |
| KR102310775B1 (ko) | 2012-05-03 | 2021-10-07 | 칼라 파마슈티컬스, 인크. | 개선된 점막 수송을 나타내는 제약 나노입자 |
| AU2013256064B2 (en) | 2012-05-03 | 2018-01-04 | Alcon Inc. | Pharmaceutical nanoparticles showing improved mucosal transport |
| US11596599B2 (en) * | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| AU2013256008B2 (en) | 2012-05-04 | 2016-02-25 | The Johns Hopkins University | Lipid-based drug carriers for rapid penetration through mucus linings |
| WO2014124006A1 (en) | 2013-02-05 | 2014-08-14 | The Johns Hopkins University | Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof |
| AU2014214846A1 (en) | 2013-02-08 | 2015-07-23 | Celgene Avilomics Research, Inc. | ERK inhibitors and uses thereof |
| JP5934677B2 (ja) * | 2013-06-18 | 2016-06-15 | 住友ゴム工業株式会社 | タイヤ用ゴム組成物、及び空気入りタイヤ |
| JP5946798B2 (ja) * | 2013-06-18 | 2016-07-06 | 住友ゴム工業株式会社 | タイヤ用ゴム組成物、及び空気入りタイヤ |
| US9492471B2 (en) | 2013-08-27 | 2016-11-15 | Celgene Avilomics Research, Inc. | Methods of treating a disease or disorder associated with Bruton'S Tyrosine Kinase |
| JP6010060B2 (ja) * | 2014-02-21 | 2016-10-19 | 住友ゴム工業株式会社 | タイヤ用ゴム組成物、及び空気入りタイヤ |
| US10005760B2 (en) | 2014-08-13 | 2018-06-26 | Celgene Car Llc | Forms and compositions of an ERK inhibitor |
| RU2639819C2 (ru) * | 2014-12-30 | 2017-12-22 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Композиция, ингибирующая теломеразу |
| CN107635545A (zh) | 2015-01-27 | 2018-01-26 | 约翰霍普金斯大学 | 用于增强粘膜表面处活性剂的输送的低渗水凝胶制剂 |
| PT3518924T (pt) | 2016-09-30 | 2022-10-27 | Salix Pharmaceuticals Inc | Formas de dispersão sólidas de rifaximina |
| US12496279B2 (en) | 2019-04-11 | 2025-12-16 | The Johns Hopkins University | Nanoparticles for drug delivery to brain |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE80467B1 (en) | 1995-07-03 | 1998-07-29 | Elan Corp Plc | Controlled release formulations for poorly soluble drugs |
| ATE232087T1 (de) | 1997-10-27 | 2003-02-15 | Merck Patent Gmbh | Feste lösungen und dispersionen von eines schlecht wasserlöslichen wirkstoffes |
| EP1103258A1 (en) | 1998-07-22 | 2001-05-30 | Yamanouchi Pharmaceutical Co. Ltd. | Solid preparation containing sparingly soluble nsaids |
| US6368622B2 (en) * | 1999-01-29 | 2002-04-09 | Abbott Laboratories | Process for preparing solid formulations of lipid regulating agents with enhanced dissolution and absorption |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US6395300B1 (en) * | 1999-05-27 | 2002-05-28 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
| US6264981B1 (en) * | 1999-10-27 | 2001-07-24 | Anesta Corporation | Oral transmucosal drug dosage using solid solution |
| DK1227797T3 (da) | 1999-11-12 | 2005-05-30 | Abbott Lab | Farmaceutiske faststofdispersionsformuleringer |
| CA2359945C (en) | 1999-11-12 | 2011-04-26 | Abbott Laboratories | Inhibitors of crystallization in a solid dispersion |
| SK12682001A3 (sk) * | 1999-12-08 | 2002-07-02 | Pharmacia Corporation, Corporate Patent Department | Celecoxib v tuhej forme so zvýšenou biologickou dostupnosťou |
| GEP20053427B (en) | 1999-12-23 | 2005-01-25 | Pfizer Prod Inc | Pharmaceutical Compositions Providing Enhanced Drug Concentrations |
| WO2001054667A1 (en) | 2000-01-28 | 2001-08-02 | Smithkline Beecham Corporation | Electrospun pharmaceutical compositions |
| AR027656A1 (es) * | 2000-03-16 | 2003-04-09 | Pfizer Prod Inc | Composiciones farmaceuticas de inhibidores de la glucogeno-fosforilasa |
| US20010053791A1 (en) * | 2000-03-16 | 2001-12-20 | Babcock Walter C. | Glycogen phosphorylase inhibitor |
| US20010036959A1 (en) | 2000-04-03 | 2001-11-01 | Gabel Rolf Dieter | Carvedilol-hydrophilic solutions |
| CA2407027C (en) | 2000-04-20 | 2011-02-15 | Rtp Pharma Inc. | Improved water-insoluble drug particle process |
| US6316029B1 (en) * | 2000-05-18 | 2001-11-13 | Flak Pharma International, Ltd. | Rapidly disintegrating solid oral dosage form |
| GB0015239D0 (en) | 2000-06-21 | 2000-08-16 | Biochemie Gmbh | Organic compounds |
| DE10038571A1 (de) | 2000-08-03 | 2002-02-14 | Knoll Ag | Zusammensetzungen und Dosierungsformen zur Anwendung in der Mundhöhle bei der Bhandlung von Mykosen |
| KR20020014570A (ko) | 2000-08-18 | 2002-02-25 | 김충섭 | 고체분산화시킨 무정형 이프리플라본의 제조방법 |
| HU229938B1 (en) * | 2001-05-03 | 2015-01-28 | Hoffmann La Roche | Pharmaceutical dosage form of amorphous nelfinavir mesylate |
| US20030054042A1 (en) * | 2001-09-14 | 2003-03-20 | Elaine Liversidge | Stabilization of chemical compounds using nanoparticulate formulations |
| EP1469833B1 (en) * | 2002-02-01 | 2021-05-19 | Bend Research, Inc. | Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus |
| US20050220880A1 (en) * | 2002-03-07 | 2005-10-06 | Lewis Andrew L | Drug carriers comprising amphiphilic block copolymers |
-
2004
- 2004-12-20 BR BRPI0418330-4A patent/BRPI0418330A/pt not_active IP Right Cessation
- 2004-12-20 US US10/596,876 patent/US8974823B2/en not_active Expired - Fee Related
- 2004-12-20 CA CA002548376A patent/CA2548376A1/en not_active Abandoned
- 2004-12-20 JP JP2006546397A patent/JP2007517016A/ja not_active Abandoned
- 2004-12-20 WO PCT/IB2004/004287 patent/WO2005065657A2/en not_active Ceased
- 2004-12-20 EP EP04806454A patent/EP1701704A2/en not_active Withdrawn
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