JP2007516296A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2007516296A5 JP2007516296A5 JP2006547427A JP2006547427A JP2007516296A5 JP 2007516296 A5 JP2007516296 A5 JP 2007516296A5 JP 2006547427 A JP2006547427 A JP 2006547427A JP 2006547427 A JP2006547427 A JP 2006547427A JP 2007516296 A5 JP2007516296 A5 JP 2007516296A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- medicament
- manufacture
- compound
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 11
- 239000003814 drug Substances 0.000 claims 6
- 238000004519 manufacturing process Methods 0.000 claims 5
- 102000003903 Cyclin-Dependent Kinases Human genes 0.000 claims 2
- 108090000266 Cyclin-Dependent Kinases Proteins 0.000 claims 2
- 241000725303 Human immunodeficiency virus Species 0.000 claims 2
- 206010047461 Viral infection Diseases 0.000 claims 2
- 208000001756 Virus Disease Diseases 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- 230000017613 viral reproduction Effects 0.000 claims 2
- 108091007476 CDKs Proteins 0.000 claims 1
- 230000000996 additive Effects 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 230000004663 cell proliferation Effects 0.000 claims 1
- 230000003463 hyperproliferative Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Claims (10)
- 式Iによって表される構造を有する化合物、その互変異性体、またはその薬学的に許容される塩の形態：
- 前記薬学的に許容される塩が下記の式を有する、請求項１に記載の化合物。
- 薬学的に許容される添加剤、及び請求項１乃至２のいずれかに記載の化合物を含む薬学的組成物。
- 医薬品として使用するための、請求項１乃至２のいずれかに記載の化合物。
- 高増殖性障害を治療するための、医薬品の製造における、請求項１乃至２のいずれかに記載の化合物の使用。
- 細胞の増殖を阻害するための、医薬品の製造における、請求項１乃至２のいずれかに記載の化合物の使用。
- ウイルス感染を治療するための、医薬品の製造における、請求項１乃至２のいずれかに記載の化合物の使用。
- 前記ウイルス感染がヒト免疫不全ウイルス（ＨＩＶ）によって引き起こされる、請求項７に記載の使用。
- 治療を必要とする患者における、サイクリン依存症キナーゼを阻害するための、医薬品の製造において、請求項１乃至２のいずれかに記載の化合物、又は前記化合物の治療学的有効量を含有する組成物の使用。
- 治療を必要とする患者に、サイクリン依存症キナーゼ関連性疾患を治療するための、医薬品の製造において、請求項１乃至２のいずれかに記載の化合物、又は前記化合物の治療学的有効量を含有する組成物の使用。
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53187203P | 2003-12-23 | 2003-12-23 | |
| US60/531,872 | 2003-12-23 | ||
| US56013804P | 2004-04-06 | 2004-04-06 | |
| US60/560,138 | 2004-04-06 | ||
| US61648004P | 2004-10-06 | 2004-10-06 | |
| US60/616,480 | 2004-10-06 | ||
| PCT/US2004/043492 WO2005063765A1 (en) | 2003-12-23 | 2004-12-21 | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007516296A JP2007516296A (ja) | 2007-06-21 |
| JP2007516296A5 true JP2007516296A5 (ja) | 2009-08-27 |
| JP4791975B2 JP4791975B2 (ja) | 2011-10-12 |
Family
ID=34743691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006547427A Expired - Fee Related JP4791975B2 (ja) | 2003-12-23 | 2004-12-21 | サイクリン依存性キナーゼの阻害剤、組成物およびそれに関連する使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8097619B2 (ja) |
| EP (1) | EP1709051A1 (ja) |
| JP (1) | JP4791975B2 (ja) |
| KR (1) | KR101155883B1 (ja) |
| AU (1) | AU2004309415B2 (ja) |
| BR (1) | BRPI0418095A (ja) |
| CA (1) | CA2551640C (ja) |
| EA (1) | EA013117B1 (ja) |
| HK (1) | HK1101399A1 (ja) |
| IL (1) | IL176543A0 (ja) |
| MX (1) | MXPA06007399A (ja) |
| NO (1) | NO20063186L (ja) |
| WO (1) | WO2005063765A1 (ja) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006002119A2 (en) * | 2004-06-18 | 2006-01-05 | Gpc Biotech, Inc. | Kinase inhibitors for treating cancers |
| EP2019101A1 (en) | 2007-07-26 | 2009-01-28 | GPC Biotech AG | Pyrazol[3,4-d]pyrimidin-4-one useful as Kinase Inhibitor |
| CN102939283B (zh) * | 2010-04-22 | 2015-06-03 | 詹森药业有限公司 | 可用作己酮糖激酶抑制剂的吲唑化合物 |
| BRPI1107312B1 (pt) | 2011-11-25 | 2021-09-08 | Universidade Federal De Santa Catarina | Composto de acil-hidrazona |
| MA46937A (fr) | 2016-11-30 | 2019-10-09 | Oncotyrol Center For Personalized Cancer Medicine Gmbh | 3-amino-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-ones en tant qu'inhibiteurs de kinases dépendantes des cyclines |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3211732A (en) | 1965-10-12 | Pyrazolob:x-d]pyrlil/hdines | ||
| CH398626A (de) | 1960-05-11 | 1966-03-15 | Ciba Geigy | Verfahren zur Herstellung neuer Pyrazolopyrimidine |
| JPS60130521A (ja) | 1983-12-19 | 1985-07-12 | Morishita Seiyaku Kk | 抗癌剤 |
| US4678499A (en) | 1985-03-11 | 1987-07-07 | E. I. Du Pont De Nemours And Company | Herbicidal sulfonamides |
| JPS6299361A (ja) | 1985-10-25 | 1987-05-08 | Morishita Seiyaku Kk | インデノ〔１，２−ｃ〕ピラゾ−ル誘導体 |
| TW444018B (en) | 1992-12-17 | 2001-07-01 | Pfizer | Pyrazolopyrimidines |
| US5593997A (en) | 1995-05-23 | 1997-01-14 | Pfizer Inc. | 4-aminopyrazolo(3-,4-D)pyrimidine and 4-aminopyrazolo-(3,4-D)pyridine tyrosine kinase inhibitors |
| US5866702A (en) | 1996-08-02 | 1999-02-02 | Cv Therapeutics, Incorporation | Purine inhibitors of cyclin dependent kinase 2 |
| US6407103B2 (en) * | 1998-04-21 | 2002-06-18 | Bristol-Myers Squibb Pharma Company | Indeno [1,2-c] pyrazol-4-ones and their uses |
| WO1999054308A1 (en) * | 1998-04-21 | 1999-10-28 | Du Pont Pharmaceuticals Company | 5-aminoindeno(1,2-c)pyrazol-4-ones as anti-cancer and anti-proliferative agents |
| US6559152B2 (en) | 1998-10-13 | 2003-05-06 | Dupont Pharmaceuticals Company | 6-substituted pyrazolo[3,4-d]pyrimidin-4-ones useful as cyclin dependent kinase inhibitors |
| US6531477B1 (en) | 1998-10-13 | 2003-03-11 | Dupont Pharmaceuticals Company | 6-substituted pyrazolo [3,4-d] pyrimidin-4-ones useful as cyclin dependent kinase inhibitors |
| US6291504B1 (en) | 1999-10-20 | 2001-09-18 | Dupont Pharmaceuticals Company | Acylsemicarbazides and their uses |
| AU2001212168A1 (en) | 2000-10-20 | 2002-05-06 | Bristol-Myers Squibb Pharma Company | Acylsemicarbazides and their use as cyclin dependent kinase (CDK) inhibitors |
| US6491971B2 (en) | 2000-11-15 | 2002-12-10 | G.T. Equipment Technologies, Inc | Release coating system for crucibles |
| WO2002044174A2 (en) | 2000-12-01 | 2002-06-06 | Bristol-Myers Squibb Pharma Company | 3-(2,4-dimethylthiazol-5-yl) indeno[1,2-c]pyrazol-4-one derivatives as cdk inhibitors |
| DE60239097D1 (de) | 2001-03-02 | 2011-03-17 | Gpc Biotech Ag | Drei-hybrid-assaysystem |
| US7605175B2 (en) * | 2001-03-02 | 2009-10-20 | Gpc Biotech Ag | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto |
| WO2003004491A1 (en) | 2001-07-06 | 2003-01-16 | Bristol-Myers Squibb Pharma Company | Semicarbazides and their uses |
| WO2003063764A2 (en) | 2001-07-10 | 2003-08-07 | Bristol-Myers Squibb Pharma Company | 6-SUBSTITUTED PYRAZOLO [3,4-d] PYRIMIDIN-4-ONES USEFUL AS CYCLIN DEPENDENT KINASE INHIBITORS |
| CA2463571A1 (en) * | 2001-10-15 | 2003-04-24 | Gpc Biotech, Inc. | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto |
| US6753329B2 (en) | 2001-12-03 | 2004-06-22 | Gpc Biotech Inc. | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto |
-
2004
- 2004-12-21 CA CA2551640A patent/CA2551640C/en not_active Expired - Fee Related
- 2004-12-21 US US10/584,485 patent/US8097619B2/en not_active Expired - Fee Related
- 2004-12-21 BR BRPI0418095-0A patent/BRPI0418095A/pt not_active IP Right Cessation
- 2004-12-21 EA EA200601216A patent/EA013117B1/ru not_active IP Right Cessation
- 2004-12-21 JP JP2006547427A patent/JP4791975B2/ja not_active Expired - Fee Related
- 2004-12-21 WO PCT/US2004/043492 patent/WO2005063765A1/en active Application Filing
- 2004-12-21 EP EP04815554A patent/EP1709051A1/en not_active Withdrawn
- 2004-12-21 KR KR1020067014820A patent/KR101155883B1/ko not_active IP Right Cessation
- 2004-12-21 AU AU2004309415A patent/AU2004309415B2/en not_active Ceased
- 2004-12-21 MX MXPA06007399A patent/MXPA06007399A/es active IP Right Grant
-
2006
- 2006-06-25 IL IL176543A patent/IL176543A0/en unknown
- 2006-07-10 NO NO20063186A patent/NO20063186L/no not_active Application Discontinuation
-
2007
- 2007-08-27 HK HK07109307.2A patent/HK1101399A1/xx not_active IP Right Cessation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009535352A5 (ja) | ||
| JP2021063088A5 (ja) | ||
| JP2013518107A5 (ja) | ||
| JP2009502743A5 (ja) | ||
| JP2017531038A5 (ja) | ||
| JP2020507589A5 (ja) | ||
| JP2011528713A5 (ja) | ||
| JP2006523216A5 (ja) | ||
| JP2013507439A5 (ja) | ||
| SI2932970T1 (en) | Antiviral therapy | |
| JP2008513510A5 (ja) | ||
| JP2016508134A5 (ja) | ||
| JP2013542247A5 (ja) | ||
| JP2017537949A5 (ja) | ||
| JP2005500357A5 (ja) | ||
| JP2010514829A5 (ja) | ||
| JP2020512337A5 (ja) | ||
| JP2008534453A5 (ja) | ||
| JP2013519645A5 (ja) | ||
| JP2007520452A5 (ja) | ||
| JP2005508955A5 (ja) | ||
| JP2014505107A5 (ja) | ||
| RU2011111117A (ru) | Лечение аутоиммунных заболеваний | |
| WO2005095345A3 (en) | Heteroaryl guanidines as inhibitors of viral replication | |
| JP2015516419A5 (ja) |