JP2007516206A5 - - Google Patents

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Publication number
JP2007516206A5
JP2007516206A5 JP2006518669A JP2006518669A JP2007516206A5 JP 2007516206 A5 JP2007516206 A5 JP 2007516206A5 JP 2006518669 A JP2006518669 A JP 2006518669A JP 2006518669 A JP2006518669 A JP 2006518669A JP 2007516206 A5 JP2007516206 A5 JP 2007516206A5
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JP
Japan
Prior art keywords
aryl
alkyl
heteroaryl
compound
conr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2006518669A
Other languages
English (en)
Japanese (ja)
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JP2007516206A (ja
Filing date
Publication date
Priority claimed from US10/874,743 external-priority patent/US7122548B2/en
Application filed filed Critical
Publication of JP2007516206A publication Critical patent/JP2007516206A/ja
Publication of JP2007516206A5 publication Critical patent/JP2007516206A5/ja
Withdrawn legal-status Critical Current

Links

JP2006518669A 2003-07-02 2004-06-25 トリアゾロトリアジン化合物およびそれらの使用 Withdrawn JP2007516206A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48422103P 2003-07-02 2003-07-02
US10/874,743 US7122548B2 (en) 2003-07-02 2004-06-24 Triazolotriazine compounds and uses thereof
PCT/US2004/020054 WO2005010005A1 (en) 2003-07-02 2004-06-25 Triazolotriazine compounds and uses thereof

Publications (2)

Publication Number Publication Date
JP2007516206A JP2007516206A (ja) 2007-06-21
JP2007516206A5 true JP2007516206A5 (enExample) 2007-08-09

Family

ID=34107700

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006518669A Withdrawn JP2007516206A (ja) 2003-07-02 2004-06-25 トリアゾロトリアジン化合物およびそれらの使用

Country Status (5)

Country Link
US (1) US7122548B2 (enExample)
EP (1) EP1644377A4 (enExample)
JP (1) JP2007516206A (enExample)
CA (1) CA2529238A1 (enExample)
WO (1) WO2005010005A1 (enExample)

Families Citing this family (43)

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US7550470B2 (en) * 2002-12-11 2009-06-23 Merck & Co. Inc. Substituted pyrazolo[1,5-A]pyrimidines as tyrosine kinase inhibitors
TWI377198B (en) 2005-08-24 2012-11-21 Eisai R&D Man Co Ltd Novel pyridine derivatives and pyrimidine derivatives (3)
RU2419620C2 (ru) * 2005-11-30 2011-05-27 Вертекс Фармасьютикалз Инкорпорейтед Ингибиторы с-мет и их применение
US7728017B2 (en) * 2005-11-30 2010-06-01 Vertex Pharmaceuticals Incorporated Inhibitors of c-Met and uses thereof
ZA200804681B (en) * 2005-11-30 2009-11-25 Vertex Pharma Inc Inhibitors of C-Met and uses thereof
RS55630B1 (sr) * 2005-12-21 2017-06-30 Janssen Pharmaceutica Nv Triazolopiridazini kao modulatori tirozin kinaze
US7723330B2 (en) 2006-03-07 2010-05-25 Array Biopharma Inc. Heterobicyclic pyrazole compounds and methods of use
US20110053931A1 (en) * 2006-06-08 2011-03-03 John Gaudino Quinoline compounds and methods of use
US8198448B2 (en) 2006-07-14 2012-06-12 Amgen Inc. Fused heterocyclic derivatives and methods of use
US8217177B2 (en) 2006-07-14 2012-07-10 Amgen Inc. Fused heterocyclic derivatives and methods of use
PE20121506A1 (es) * 2006-07-14 2012-11-26 Amgen Inc Compuestos triazolopiridinas como inhibidores de c-met
US7683060B2 (en) * 2006-08-07 2010-03-23 Incyte Corporation Triazolotriazines as kinase inhibitors
ATE535520T1 (de) 2006-08-23 2011-12-15 Eisai R&D Man Co Ltd Salz eines phenoxypyridinderivats oder kristall davon und verfahren zu dessen herstellung
US7790885B2 (en) 2006-08-31 2010-09-07 Eisai R&D Management Co., Ltd. Process for preparing phenoxypyridine derivatives
WO2008030744A2 (en) * 2006-09-05 2008-03-13 Board Of Regents, The University Of Texas System Inhibitors of c-met and uses thereof
NZ575548A (en) * 2006-09-18 2011-09-30 Vertex Pharma Heterocyclic inhibitors of c-Met and uses thereof
BRPI0717320A2 (pt) * 2006-10-23 2013-10-22 Sgx Pharmaceuticals Inc Triazóis bicíclicos como moduladores de proteína cinase
MX2009004426A (es) 2006-10-23 2009-08-12 Cephalon Inc Derivados biciclicos fusionados de 2,4-diaminopirimidina como inhibidores alk y c-met.
GEP20125658B (en) * 2006-11-22 2012-10-10 Incyte Corp Imidazotriazines and imidazo pyrimidines as kinase inhibitors
AU2007338792B2 (en) 2006-12-20 2012-05-31 Amgen Inc. Substituted heterocycles and methods of use
WO2008079294A1 (en) * 2006-12-20 2008-07-03 Amgen Inc. Substituted heterocycles and methods of use
US8066118B1 (en) 2006-12-25 2011-11-29 Marty Van Tassell Device for using nonwoven towels in the dairy industry
EP2170894A1 (en) * 2007-06-21 2010-04-07 Janssen Pharmaceutica N.V. Polymorphic and hydrate forms, salts and process for preparing 6-{difluoro[6-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}quinoline
JP2009132660A (ja) 2007-11-30 2009-06-18 Eisai R & D Management Co Ltd 食道癌治療用組成物
PE20091468A1 (es) 2008-02-28 2009-10-22 Novartis Ag DERIVADOS DE 3-METIL-IMIDAZO-[1,2-b]-PIRIDAZINA
SI2300455T1 (sl) 2008-05-21 2017-12-29 Incyte Holdings Corporation Soli 2-fluoro-n-metil-4-(7-(kinolin-6-il-metil)-imidazo(1,2-b)1,2,4) triazin-2-il)benzamid in postopki v zvezi z njihovo pripravo
JP2011520986A (ja) 2008-05-22 2011-07-21 アムジエン・インコーポレーテツド タンパク質キナーゼ阻害薬としての複素環類
EP2321433A2 (en) * 2008-08-29 2011-05-18 F. Hoffmann-La Roche AG Diagnostics and treatments for vegf-independent tumors
AU2009300328A1 (en) * 2008-10-01 2010-04-08 Ludwig Institute For Cancer Research Methods for the treatment of cancer
EP2356116A1 (en) 2008-11-20 2011-08-17 OSI Pharmaceuticals, Inc. Substituted pyrroloý2,3-b¨-pyridines and-pyrazines
UA106082C2 (uk) * 2009-05-28 2014-07-25 Вертекс Фармасьютікалз Інкорпорейтед АМІНОПІРАЗОЛ ТРИАЗОЛОТІАДІАЗОЛЬНІ ІНГІБІТОРИ ПРОТЕЇНКІНАЗИ c-МЕТ
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
BR112012003262A8 (pt) 2009-08-12 2016-05-17 Novartis Ag compostos de hidrazona heterocíclica e seus usos para tratar câncer e inflamação
IN2012DN01453A (enExample) 2009-08-20 2015-06-05 Novartis Ag
PT3511330T (pt) 2009-12-31 2020-12-24 Hutchison Medipharma Ltd Intermediário sintético útil na preparação de inibidores de triazolopiridina c-met
MX2012008898A (es) 2010-02-03 2012-11-06 Incyte Corp Imidazo - [1, 2 - b] [1, 2, 4] triazinas como inhibidores de c - met.
US20130072495A1 (en) 2010-05-14 2013-03-21 OSI Pharmaceuticals, LLC Fused bicyclic kinase inhibitors
AR081039A1 (es) 2010-05-14 2012-05-30 Osi Pharmaceuticals Llc Inhibidores biciclicos fusionados de quinasa
CN102532141A (zh) 2010-12-08 2012-07-04 中国科学院上海药物研究所 [1，2，4]三唑并[4，3-b][1，2，4]三嗪类化合物、其制备方法和用途
JP2014513724A (ja) 2011-05-16 2014-06-05 オーエスアイ・ファーマシューティカルズ，エルエルシー 融合二環キナーゼ阻害剤
WO2013152252A1 (en) 2012-04-06 2013-10-10 OSI Pharmaceuticals, LLC Combination anti-cancer therapy
EP3122900A1 (en) 2014-03-24 2017-02-01 F. Hoffmann-La Roche AG Cancer treatment with c-met antagonists and correlation of the latter with hgf expression
CN111205291B (zh) * 2018-11-22 2022-08-23 上海科技大学 三唑并环类化合物、其制备方法、中间体和应用

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FR1379480A (fr) 1963-01-16 1964-11-20 Ilford Ltd Nouveaux penta-aza-indènes, préparation et utilisation de ces composés
GB1042471A (en) 1963-01-16 1966-09-14 Ilford Ltd Penta-azaindenes, their production and use in photographic emulsions
GB1028809A (en) 1964-01-21 1966-05-11 Ferrania Spa Process for stabilizing photographic emulsions
US4405619A (en) 1981-09-02 1983-09-20 Diamond Shamrock Corporation Antiinflammatory substituted-1,2,4-triazolo[4,3-b]-1,2,4-triazines
IT1269176B (it) 1994-01-11 1997-03-21 Isagro Srl Eterobicicli ad attivita' fungicida

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