JP2007516206A - トリアゾロトリアジン化合物およびそれらの使用 - Google Patents
トリアゾロトリアジン化合物およびそれらの使用 Download PDFInfo
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- JP2007516206A JP2007516206A JP2006518669A JP2006518669A JP2007516206A JP 2007516206 A JP2007516206 A JP 2007516206A JP 2006518669 A JP2006518669 A JP 2006518669A JP 2006518669 A JP2006518669 A JP 2006518669A JP 2007516206 A JP2007516206 A JP 2007516206A
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48422103P | 2003-07-02 | 2003-07-02 | |
| US10/874,743 US7122548B2 (en) | 2003-07-02 | 2004-06-24 | Triazolotriazine compounds and uses thereof |
| PCT/US2004/020054 WO2005010005A1 (en) | 2003-07-02 | 2004-06-25 | Triazolotriazine compounds and uses thereof |
Publications (2)
| Publication Number | Publication Date |
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| JP2007516206A true JP2007516206A (ja) | 2007-06-21 |
| JP2007516206A5 JP2007516206A5 (enExample) | 2007-08-09 |
Family
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| Application Number | Title | Priority Date | Filing Date |
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| JP2006518669A Withdrawn JP2007516206A (ja) | 2003-07-02 | 2004-06-25 | トリアゾロトリアジン化合物およびそれらの使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7122548B2 (enExample) |
| EP (1) | EP1644377A4 (enExample) |
| JP (1) | JP2007516206A (enExample) |
| CA (1) | CA2529238A1 (enExample) |
| WO (1) | WO2005010005A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7550470B2 (en) * | 2002-12-11 | 2009-06-23 | Merck & Co. Inc. | Substituted pyrazolo[1,5-A]pyrimidines as tyrosine kinase inhibitors |
| ES2424651T3 (es) | 2005-08-24 | 2013-10-07 | Eisai R&D Management Co., Ltd. | Nuevo derivado de piridina y derivado de pirimidina (3) |
| AU2006320580B2 (en) * | 2005-11-30 | 2011-06-23 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-Met and uses thereof |
| CN101360748B (zh) * | 2005-11-30 | 2012-05-30 | 沃泰克斯药物股份有限公司 | c-MET抑制剂及其应用 |
| RU2419620C2 (ru) * | 2005-11-30 | 2011-05-27 | Вертекс Фармасьютикалз Инкорпорейтед | Ингибиторы с-мет и их применение |
| EP1966214B9 (en) * | 2005-12-21 | 2017-09-13 | Janssen Pharmaceutica N.V. | Triazolopyridazines as tyrosine kinase modulators |
| WO2007103308A2 (en) | 2006-03-07 | 2007-09-13 | Array Biopharma Inc. | Heterobicyclic pyrazole compounds and methods of use |
| CN101528702A (zh) * | 2006-06-08 | 2009-09-09 | 阿雷生物药品公司 | 喹啉化合物和使用方法 |
| PE20121506A1 (es) * | 2006-07-14 | 2012-11-26 | Amgen Inc | Compuestos triazolopiridinas como inhibidores de c-met |
| US8217177B2 (en) | 2006-07-14 | 2012-07-10 | Amgen Inc. | Fused heterocyclic derivatives and methods of use |
| US8198448B2 (en) | 2006-07-14 | 2012-06-12 | Amgen Inc. | Fused heterocyclic derivatives and methods of use |
| TW200817410A (en) * | 2006-08-07 | 2008-04-16 | Incyte Corp | Triazolotriazines as kinase inhibitors |
| JP5190365B2 (ja) | 2006-08-23 | 2013-04-24 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | フェノキシピリジン誘導体の塩またはその結晶およびそれらの製造方法 |
| US7790885B2 (en) | 2006-08-31 | 2010-09-07 | Eisai R&D Management Co., Ltd. | Process for preparing phenoxypyridine derivatives |
| WO2008030744A2 (en) * | 2006-09-05 | 2008-03-13 | Board Of Regents, The University Of Texas System | Inhibitors of c-met and uses thereof |
| JP2010519174A (ja) * | 2006-09-18 | 2010-06-03 | バーテックス ファーマシューティカルズ インコーポレイテッド | ｃ−Ｍｅｔの複素環阻害薬およびその使用方法 |
| NZ576425A (en) | 2006-10-23 | 2012-04-27 | Cephalon Inc | Fused bicyclic derivatives of 2,4-diaminopyrimidine as alk and c-met inhibitors |
| DK2084162T3 (da) * | 2006-10-23 | 2012-10-01 | Sgx Pharmaceuticals Inc | Bicykliske triazoler som proteinkinasemodulatorer |
| EP2497470B8 (en) * | 2006-11-22 | 2015-12-02 | Incyte Holdings Corporation | Imidazotriazines and imidazopyrimidines as kinase inhibitors |
| US7687522B2 (en) | 2006-12-20 | 2010-03-30 | Amgen Inc. | Substituted pyridines and pyrimidines and their use in treatment of cancer |
| EP2125780B1 (en) * | 2006-12-20 | 2012-08-29 | Amgen Inc. | Substituted heterocycles and methods of use |
| US8066118B1 (en) | 2006-12-25 | 2011-11-29 | Marty Van Tassell | Device for using nonwoven towels in the dairy industry |
| WO2008155378A1 (en) * | 2007-06-21 | 2008-12-24 | Janssen Pharmaceutica Nv | Polymorphic and hydrate forms, salts and process for preparing 6-{difluoro[6-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}quinoline |
| JP2009132660A (ja) | 2007-11-30 | 2009-06-18 | Eisai R & D Management Co Ltd | 食道癌治療用組成物 |
| JP5576802B2 (ja) | 2008-02-28 | 2014-08-20 | ノバルティス アーゲー | Ｃ−Ｍｅｔチロシンキナーゼ介在疾患の治療用のイミダゾ［１，２−ｂ］ピリダジン誘導体 |
| NZ589622A (en) | 2008-05-21 | 2012-10-26 | Incyte Corp | Salts of 2-fluoro-N-methyl-4-[7-(quinolin-6-yl-methyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide and processes related to preparing the same |
| MX2010012528A (es) | 2008-05-22 | 2010-12-02 | Amgen Inc | Heterociclos como inhibidores de proteina cinasa. |
| US20100055099A1 (en) * | 2008-08-29 | 2010-03-04 | Ellen Filvaroff | Diagnostics and Treatments for VEGF-Independent Tumors |
| WO2010039248A1 (en) * | 2008-10-01 | 2010-04-08 | Ludwig Institute For Cancer Research | Methods for the treatment of cancer |
| JP2012509342A (ja) | 2008-11-20 | 2012-04-19 | オーエスアイ・フアーマスーテイカルズ・インコーポレーテツド | 置換ピロロ［２，３−ｂ］−ピリジンおよび−ピラジン |
| EP2435443B1 (en) * | 2009-05-28 | 2013-07-31 | Vertex Pharmaceuticals Incorporated | Aminopyrazole triazolothiadiazole inhibitors of c-met protien kinase |
| US8389526B2 (en) | 2009-08-07 | 2013-03-05 | Novartis Ag | 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives |
| KR20120089643A (ko) | 2009-08-12 | 2012-08-13 | 노파르티스 아게 | 헤테로시클릭 히드라존 화합물, 및 암 및 염증을 치료하기 위한 그의 용도 |
| JP5775871B2 (ja) | 2009-08-20 | 2015-09-09 | ノバルティス アーゲー | ヘテロ環式オキシム化合物 |
| EP2719699B1 (en) | 2009-12-31 | 2015-07-08 | Hutchison Medipharma Limited | Certain triazolopyrazines, compositions thereof and methods of use therefor |
| KR101870878B1 (ko) | 2010-02-03 | 2018-06-25 | 인사이트 홀딩스 코포레이션 | Ｃ―ＭＥＴ 억제제로서의 이미다조〔１，２―ｂ〕〔１，２，４〕트리아진 |
| US20130072495A1 (en) | 2010-05-14 | 2013-03-21 | OSI Pharmaceuticals, LLC | Fused bicyclic kinase inhibitors |
| AR081039A1 (es) | 2010-05-14 | 2012-05-30 | Osi Pharmaceuticals Llc | Inhibidores biciclicos fusionados de quinasa |
| CN102532141A (zh) | 2010-12-08 | 2012-07-04 | 中国科学院上海药物研究所 | [1，2，4]三唑并[4，3-b][1，2，4]三嗪类化合物、其制备方法和用途 |
| JP2014513724A (ja) | 2011-05-16 | 2014-06-05 | オーエスアイ・ファーマシューティカルズ，エルエルシー | 融合二環キナーゼ阻害剤 |
| WO2013152252A1 (en) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy |
| EP3122900A1 (en) | 2014-03-24 | 2017-02-01 | F. Hoffmann-La Roche AG | Cancer treatment with c-met antagonists and correlation of the latter with hgf expression |
| CN111205291B (zh) * | 2018-11-22 | 2022-08-23 | 上海科技大学 | 三唑并环类化合物、其制备方法、中间体和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1379480A (fr) | 1963-01-16 | 1964-11-20 | Ilford Ltd | Nouveaux penta-aza-indènes, préparation et utilisation de ces composés |
| GB1042471A (en) | 1963-01-16 | 1966-09-14 | Ilford Ltd | Penta-azaindenes, their production and use in photographic emulsions |
| GB1028809A (en) | 1964-01-21 | 1966-05-11 | Ferrania Spa | Process for stabilizing photographic emulsions |
| US4405619A (en) | 1981-09-02 | 1983-09-20 | Diamond Shamrock Corporation | Antiinflammatory substituted-1,2,4-triazolo[4,3-b]-1,2,4-triazines |
| IT1269176B (it) | 1994-01-11 | 1997-03-21 | Isagro Srl | Eterobicicli ad attivita' fungicida |
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2004
- 2004-06-24 US US10/874,743 patent/US7122548B2/en not_active Expired - Fee Related
- 2004-06-25 CA CA002529238A patent/CA2529238A1/en not_active Abandoned
- 2004-06-25 WO PCT/US2004/020054 patent/WO2005010005A1/en not_active Ceased
- 2004-06-25 JP JP2006518669A patent/JP2007516206A/ja not_active Withdrawn
- 2004-06-25 EP EP04776943A patent/EP1644377A4/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CA2529238A1 (en) | 2005-02-03 |
| WO2005010005A1 (en) | 2005-02-03 |
| EP1644377A4 (en) | 2007-09-05 |
| US20050075340A1 (en) | 2005-04-07 |
| EP1644377A1 (en) | 2006-04-12 |
| US7122548B2 (en) | 2006-10-17 |
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