JP2007516206A - トリアゾロトリアジン化合物およびそれらの使用 - Google Patents
トリアゾロトリアジン化合物およびそれらの使用 Download PDFInfo
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- JP2007516206A JP2007516206A JP2006518669A JP2006518669A JP2007516206A JP 2007516206 A JP2007516206 A JP 2007516206A JP 2006518669 A JP2006518669 A JP 2006518669A JP 2006518669 A JP2006518669 A JP 2006518669A JP 2007516206 A JP2007516206 A JP 2007516206A
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- Reproductive Health (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48422103P | 2003-07-02 | 2003-07-02 | |
| US10/874,743 US7122548B2 (en) | 2003-07-02 | 2004-06-24 | Triazolotriazine compounds and uses thereof |
| PCT/US2004/020054 WO2005010005A1 (en) | 2003-07-02 | 2004-06-25 | Triazolotriazine compounds and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007516206A true JP2007516206A (ja) | 2007-06-21 |
| JP2007516206A5 JP2007516206A5 (enExample) | 2007-08-09 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006518669A Withdrawn JP2007516206A (ja) | 2003-07-02 | 2004-06-25 | トリアゾロトリアジン化合物およびそれらの使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7122548B2 (enExample) |
| EP (1) | EP1644377A4 (enExample) |
| JP (1) | JP2007516206A (enExample) |
| CA (1) | CA2529238A1 (enExample) |
| WO (1) | WO2005010005A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7550470B2 (en) * | 2002-12-11 | 2009-06-23 | Merck & Co. Inc. | Substituted pyrazolo[1,5-A]pyrimidines as tyrosine kinase inhibitors |
| TWI377198B (en) | 2005-08-24 | 2012-11-21 | Eisai R&D Man Co Ltd | Novel pyridine derivatives and pyrimidine derivatives (3) |
| RU2419620C2 (ru) * | 2005-11-30 | 2011-05-27 | Вертекс Фармасьютикалз Инкорпорейтед | Ингибиторы с-мет и их применение |
| US7728017B2 (en) * | 2005-11-30 | 2010-06-01 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-Met and uses thereof |
| ZA200804681B (en) * | 2005-11-30 | 2009-11-25 | Vertex Pharma Inc | Inhibitors of C-Met and uses thereof |
| RS55630B1 (sr) * | 2005-12-21 | 2017-06-30 | Janssen Pharmaceutica Nv | Triazolopiridazini kao modulatori tirozin kinaze |
| US7723330B2 (en) | 2006-03-07 | 2010-05-25 | Array Biopharma Inc. | Heterobicyclic pyrazole compounds and methods of use |
| US20110053931A1 (en) * | 2006-06-08 | 2011-03-03 | John Gaudino | Quinoline compounds and methods of use |
| US8198448B2 (en) | 2006-07-14 | 2012-06-12 | Amgen Inc. | Fused heterocyclic derivatives and methods of use |
| US8217177B2 (en) | 2006-07-14 | 2012-07-10 | Amgen Inc. | Fused heterocyclic derivatives and methods of use |
| PE20121506A1 (es) * | 2006-07-14 | 2012-11-26 | Amgen Inc | Compuestos triazolopiridinas como inhibidores de c-met |
| US7683060B2 (en) * | 2006-08-07 | 2010-03-23 | Incyte Corporation | Triazolotriazines as kinase inhibitors |
| ATE535520T1 (de) | 2006-08-23 | 2011-12-15 | Eisai R&D Man Co Ltd | Salz eines phenoxypyridinderivats oder kristall davon und verfahren zu dessen herstellung |
| US7790885B2 (en) | 2006-08-31 | 2010-09-07 | Eisai R&D Management Co., Ltd. | Process for preparing phenoxypyridine derivatives |
| WO2008030744A2 (en) * | 2006-09-05 | 2008-03-13 | Board Of Regents, The University Of Texas System | Inhibitors of c-met and uses thereof |
| NZ575548A (en) * | 2006-09-18 | 2011-09-30 | Vertex Pharma | Heterocyclic inhibitors of c-Met and uses thereof |
| BRPI0717320A2 (pt) * | 2006-10-23 | 2013-10-22 | Sgx Pharmaceuticals Inc | Triazóis bicíclicos como moduladores de proteína cinase |
| MX2009004426A (es) | 2006-10-23 | 2009-08-12 | Cephalon Inc | Derivados biciclicos fusionados de 2,4-diaminopirimidina como inhibidores alk y c-met. |
| GEP20125658B (en) * | 2006-11-22 | 2012-10-10 | Incyte Corp | Imidazotriazines and imidazo pyrimidines as kinase inhibitors |
| AU2007338792B2 (en) | 2006-12-20 | 2012-05-31 | Amgen Inc. | Substituted heterocycles and methods of use |
| WO2008079294A1 (en) * | 2006-12-20 | 2008-07-03 | Amgen Inc. | Substituted heterocycles and methods of use |
| US8066118B1 (en) | 2006-12-25 | 2011-11-29 | Marty Van Tassell | Device for using nonwoven towels in the dairy industry |
| EP2170894A1 (en) * | 2007-06-21 | 2010-04-07 | Janssen Pharmaceutica N.V. | Polymorphic and hydrate forms, salts and process for preparing 6-{difluoro[6-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}quinoline |
| JP2009132660A (ja) | 2007-11-30 | 2009-06-18 | Eisai R & D Management Co Ltd | 食道癌治療用組成物 |
| PE20091468A1 (es) | 2008-02-28 | 2009-10-22 | Novartis Ag | DERIVADOS DE 3-METIL-IMIDAZO-[1,2-b]-PIRIDAZINA |
| SI2300455T1 (sl) | 2008-05-21 | 2017-12-29 | Incyte Holdings Corporation | Soli 2-fluoro-n-metil-4-(7-(kinolin-6-il-metil)-imidazo(1,2-b)1,2,4) triazin-2-il)benzamid in postopki v zvezi z njihovo pripravo |
| JP2011520986A (ja) | 2008-05-22 | 2011-07-21 | アムジエン・インコーポレーテツド | タンパク質キナーゼ阻害薬としての複素環類 |
| EP2321433A2 (en) * | 2008-08-29 | 2011-05-18 | F. Hoffmann-La Roche AG | Diagnostics and treatments for vegf-independent tumors |
| AU2009300328A1 (en) * | 2008-10-01 | 2010-04-08 | Ludwig Institute For Cancer Research | Methods for the treatment of cancer |
| EP2356116A1 (en) | 2008-11-20 | 2011-08-17 | OSI Pharmaceuticals, Inc. | Substituted pyrroloý2,3-b¨-pyridines and-pyrazines |
| UA106082C2 (uk) * | 2009-05-28 | 2014-07-25 | Вертекс Фармасьютікалз Інкорпорейтед | АМІНОПІРАЗОЛ ТРИАЗОЛОТІАДІАЗОЛЬНІ ІНГІБІТОРИ ПРОТЕЇНКІНАЗИ c-МЕТ |
| US8389526B2 (en) | 2009-08-07 | 2013-03-05 | Novartis Ag | 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives |
| BR112012003262A8 (pt) | 2009-08-12 | 2016-05-17 | Novartis Ag | compostos de hidrazona heterocíclica e seus usos para tratar câncer e inflamação |
| IN2012DN01453A (enExample) | 2009-08-20 | 2015-06-05 | Novartis Ag | |
| PT3511330T (pt) | 2009-12-31 | 2020-12-24 | Hutchison Medipharma Ltd | Intermediário sintético útil na preparação de inibidores de triazolopiridina c-met |
| MX2012008898A (es) | 2010-02-03 | 2012-11-06 | Incyte Corp | Imidazo - [1, 2 - b] [1, 2, 4] triazinas como inhibidores de c - met. |
| US20130072495A1 (en) | 2010-05-14 | 2013-03-21 | OSI Pharmaceuticals, LLC | Fused bicyclic kinase inhibitors |
| AR081039A1 (es) | 2010-05-14 | 2012-05-30 | Osi Pharmaceuticals Llc | Inhibidores biciclicos fusionados de quinasa |
| CN102532141A (zh) | 2010-12-08 | 2012-07-04 | 中国科学院上海药物研究所 | [1，2，4]三唑并[4，3-b][1，2，4]三嗪类化合物、其制备方法和用途 |
| JP2014513724A (ja) | 2011-05-16 | 2014-06-05 | オーエスアイ・ファーマシューティカルズ，エルエルシー | 融合二環キナーゼ阻害剤 |
| WO2013152252A1 (en) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy |
| EP3122900A1 (en) | 2014-03-24 | 2017-02-01 | F. Hoffmann-La Roche AG | Cancer treatment with c-met antagonists and correlation of the latter with hgf expression |
| CN111205291B (zh) * | 2018-11-22 | 2022-08-23 | 上海科技大学 | 三唑并环类化合物、其制备方法、中间体和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1379480A (fr) | 1963-01-16 | 1964-11-20 | Ilford Ltd | Nouveaux penta-aza-indènes, préparation et utilisation de ces composés |
| GB1042471A (en) | 1963-01-16 | 1966-09-14 | Ilford Ltd | Penta-azaindenes, their production and use in photographic emulsions |
| GB1028809A (en) | 1964-01-21 | 1966-05-11 | Ferrania Spa | Process for stabilizing photographic emulsions |
| US4405619A (en) | 1981-09-02 | 1983-09-20 | Diamond Shamrock Corporation | Antiinflammatory substituted-1,2,4-triazolo[4,3-b]-1,2,4-triazines |
| IT1269176B (it) | 1994-01-11 | 1997-03-21 | Isagro Srl | Eterobicicli ad attivita' fungicida |
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2004
- 2004-06-24 US US10/874,743 patent/US7122548B2/en not_active Expired - Fee Related
- 2004-06-25 JP JP2006518669A patent/JP2007516206A/ja not_active Withdrawn
- 2004-06-25 WO PCT/US2004/020054 patent/WO2005010005A1/en not_active Ceased
- 2004-06-25 EP EP04776943A patent/EP1644377A4/en not_active Withdrawn
- 2004-06-25 CA CA002529238A patent/CA2529238A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1644377A1 (en) | 2006-04-12 |
| WO2005010005A1 (en) | 2005-02-03 |
| CA2529238A1 (en) | 2005-02-03 |
| US20050075340A1 (en) | 2005-04-07 |
| US7122548B2 (en) | 2006-10-17 |
| EP1644377A4 (en) | 2007-09-05 |
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