JP2007516164A5 - - Google Patents

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Publication number
JP2007516164A5
JP2007516164A5 JP2006516467A JP2006516467A JP2007516164A5 JP 2007516164 A5 JP2007516164 A5 JP 2007516164A5 JP 2006516467 A JP2006516467 A JP 2006516467A JP 2006516467 A JP2006516467 A JP 2006516467A JP 2007516164 A5 JP2007516164 A5 JP 2007516164A5
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JP
Japan
Prior art keywords
alkyl
ring
aryl
substituted
fluorines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006516467A
Other languages
English (en)
Japanese (ja)
Other versions
JP4701167B2 (ja
JP2007516164A (ja
Filing date
Publication date
Priority claimed from SE0301922A external-priority patent/SE0301922D0/xx
Application filed filed Critical
Publication of JP2007516164A publication Critical patent/JP2007516164A/ja
Publication of JP2007516164A5 publication Critical patent/JP2007516164A5/ja
Application granted granted Critical
Publication of JP4701167B2 publication Critical patent/JP4701167B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2006516467A 2003-06-27 2004-06-23 メタロプロテイナーゼ阻害剤としてのn−{(4−置換ピペラジン−1−スルホニルメチル)アルキル}−n−ヒドロキシホルムアミド化合物 Expired - Fee Related JP4701167B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0301922A SE0301922D0 (sv) 2003-06-27 2003-06-27 Novel compounds
SE0301922-1 2003-06-27
PCT/GB2004/002702 WO2005000822A1 (en) 2003-06-27 2004-06-23 N-{‘4-substituted piperazine-1-sulfonylmethyl!alkyl}-n-hydroxyfomamide compounds as metalloproteinase inhibitors

Publications (3)

Publication Number Publication Date
JP2007516164A JP2007516164A (ja) 2007-06-21
JP2007516164A5 true JP2007516164A5 (enExample) 2007-08-02
JP4701167B2 JP4701167B2 (ja) 2011-06-15

Family

ID=27656653

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006516467A Expired - Fee Related JP4701167B2 (ja) 2003-06-27 2004-06-23 メタロプロテイナーゼ阻害剤としてのn−{(4−置換ピペラジン−1−スルホニルメチル)アルキル}−n−ヒドロキシホルムアミド化合物

Country Status (33)

Country Link
US (1) US7485644B2 (enExample)
EP (1) EP1644340B1 (enExample)
JP (1) JP4701167B2 (enExample)
KR (1) KR20060026440A (enExample)
CN (2) CN1812974B (enExample)
AR (1) AR044931A1 (enExample)
AT (1) ATE414063T1 (enExample)
AU (1) AU2004251104B2 (enExample)
BR (1) BRPI0411929A (enExample)
CA (1) CA2529468A1 (enExample)
CO (1) CO5650254A2 (enExample)
CY (1) CY1108757T1 (enExample)
DE (1) DE602004017733D1 (enExample)
DK (1) DK1644340T3 (enExample)
ES (1) ES2315675T3 (enExample)
HR (1) HRP20090009T3 (enExample)
IL (1) IL172615A0 (enExample)
IS (1) IS8257A (enExample)
MX (1) MXPA05013460A (enExample)
MY (1) MY138680A (enExample)
NO (1) NO20060444L (enExample)
NZ (1) NZ544208A (enExample)
PL (1) PL1644340T3 (enExample)
PT (1) PT1644340E (enExample)
RU (1) RU2351595C2 (enExample)
SA (1) SA04250224B1 (enExample)
SE (1) SE0301922D0 (enExample)
SI (1) SI1644340T1 (enExample)
TW (1) TW200524898A (enExample)
UA (1) UA81491C2 (enExample)
UY (1) UY28387A1 (enExample)
WO (1) WO2005000822A1 (enExample)
ZA (1) ZA200510458B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0427403D0 (en) 2004-12-15 2005-01-19 Astrazeneca Ab Novel compounds I
JP5203956B2 (ja) * 2005-10-26 2013-06-05 メルク セローノ ソシエテ アノニム メタロプロテイナーゼの調節のためのスルホンアミド誘導体とその使用
CN101007794B (zh) * 2006-01-26 2010-09-01 中国科学院上海药物研究所 N,n'-二取代哌嗪类衍生物及其制备方法、药物组合物和用途
WO2009151910A2 (en) * 2008-05-25 2009-12-17 Wyeth Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer
KR101822444B1 (ko) * 2010-07-08 2018-01-26 가켄 세이야쿠 가부시키가이샤 N-히드록시포름아미드 유도체 및 그를 함유하는 의약

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100402496C (zh) * 1998-01-30 2008-07-16 达尔文发现有限公司 用作基质金属蛋白酶抑制剂的化合物
GB9919776D0 (en) * 1998-08-31 1999-10-27 Zeneca Ltd Compoujnds
JP2003501414A (ja) * 1999-06-04 2003-01-14 アストラゼネカ・アクチエボラーグ メタロプロテイナーゼの阻害剤
IL150806A0 (en) * 2000-02-21 2003-02-12 Astrazeneca Ab Piperidine-and piperazine substituted n-hydroxyformamides as inhibitors of metalloproteinases
GB0119472D0 (en) * 2001-08-09 2001-10-03 Astrazeneca Ab Compounds
AU2003221786A1 (en) * 2002-04-25 2003-11-10 Pharmacia Corporation Piperidinyl-and piperazinyl-sulfonylmethyl hydroxamic acids and their use as protease inhibitors
WO2004113312A1 (en) * 2003-06-19 2004-12-29 Celltech R & D Limited Hydroxamate sulfonamides as cd23 shedding inhibitors

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