JP2007515469A5 - - Google Patents
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- JP2007515469A5 JP2007515469A5 JP2006546357A JP2006546357A JP2007515469A5 JP 2007515469 A5 JP2007515469 A5 JP 2007515469A5 JP 2006546357 A JP2006546357 A JP 2006546357A JP 2006546357 A JP2006546357 A JP 2006546357A JP 2007515469 A5 JP2007515469 A5 JP 2007515469A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- use according
- patient
- group
- antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53163903P | 2003-12-22 | 2003-12-22 | |
| PCT/IB2004/004103 WO2005063289A1 (en) | 2003-12-22 | 2004-12-09 | Cd40 antibody formulation and methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011100868A Division JP5634321B2 (ja) | 2003-12-22 | 2011-04-28 | Cd40抗体製剤および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007515469A JP2007515469A (ja) | 2007-06-14 |
| JP2007515469A5 true JP2007515469A5 (enExample) | 2008-01-31 |
Family
ID=34738672
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006546357A Pending JP2007515469A (ja) | 2003-12-22 | 2004-12-09 | Cd40抗体製剤および方法 |
| JP2011100868A Expired - Fee Related JP5634321B2 (ja) | 2003-12-22 | 2011-04-28 | Cd40抗体製剤および方法 |
| JP2014121342A Pending JP2014205692A (ja) | 2003-12-22 | 2014-06-12 | Cd40抗体製剤および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011100868A Expired - Fee Related JP5634321B2 (ja) | 2003-12-22 | 2011-04-28 | Cd40抗体製剤および方法 |
| JP2014121342A Pending JP2014205692A (ja) | 2003-12-22 | 2014-06-12 | Cd40抗体製剤および方法 |
Country Status (20)
| Country | Link |
|---|---|
| US (4) | US20050136055A1 (enExample) |
| EP (3) | EP2218461B1 (enExample) |
| JP (3) | JP2007515469A (enExample) |
| KR (2) | KR100847944B1 (enExample) |
| CN (2) | CN1897971A (enExample) |
| AU (1) | AU2004308749B2 (enExample) |
| BR (1) | BRPI0418029B8 (enExample) |
| CA (2) | CA2549652C (enExample) |
| DK (1) | DK2218461T3 (enExample) |
| ES (1) | ES2580002T3 (enExample) |
| HU (1) | HUE027717T2 (enExample) |
| IL (2) | IL175540A (enExample) |
| NO (1) | NO343797B1 (enExample) |
| NZ (2) | NZ547162A (enExample) |
| PL (1) | PL2218461T3 (enExample) |
| RU (1) | RU2355421C2 (enExample) |
| SI (1) | SI2218461T1 (enExample) |
| TW (1) | TWI359671B (enExample) |
| WO (1) | WO2005063289A1 (enExample) |
| ZA (1) | ZA200603804B (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6946129B1 (en) | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
| US7658924B2 (en) * | 2001-10-11 | 2010-02-09 | Amgen Inc. | Angiopoietin-2 specific binding agents |
| MX2008007140A (es) * | 2005-12-09 | 2009-03-04 | Seattle Genetics Inc | Metodos para utilizar agentes de union a cd40. |
| EP2019857B1 (en) * | 2006-05-03 | 2016-09-28 | The Regents of the University of Colorado, a body corporate | Cd40 agonist antibody/type1 interferon synergistic adjuvant combination, conjugates containing and use thereof as a therapeutic to enhance cellular immunity |
| US20090074711A1 (en) * | 2006-09-07 | 2009-03-19 | University Of Southhampton | Human therapies using chimeric agonistic anti-human cd40 antibody |
| EP3392273A1 (en) | 2007-05-30 | 2018-10-24 | Xencor, Inc. | Methods and compositions for inhibiting cd32b expressing cells |
| JO2913B1 (en) | 2008-02-20 | 2015-09-15 | امجين إنك, | Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses |
| CA2735421A1 (en) * | 2008-08-29 | 2010-03-04 | Academisch Ziekenhuis Leiden H.O.D.N. Lumc | Delivery of a cd40 agonist to a tumor draining lymph node of a subject |
| US9561214B2 (en) * | 2008-10-16 | 2017-02-07 | Array Biopharma Inc. | Method of treatment using inhibitors of mitosis |
| WO2011101332A1 (en) | 2010-02-16 | 2011-08-25 | Proyecto De Biomedicina Cima, S.L. | Compositions based on the fibronectin extracellular domain a for the treatment of melanoma |
| WO2012123269A1 (en) | 2011-03-11 | 2012-09-20 | Proyecto De Biomedicina Cima, S.L. | Immunogenic compositions and methods for their use |
| EP2505640A1 (en) | 2011-03-29 | 2012-10-03 | Neo Virnatech, S.L. | Vaccine compositions for birnavirus-borne diseases |
| EP2702078B1 (en) | 2011-04-29 | 2018-11-07 | Apexigen, Inc. | Anti-cd40 antibodies and methods of use |
| NZ701324A (en) | 2012-05-04 | 2016-09-30 | Pfizer | Prostate-associated antigens and vaccine-based immunotherapy regimens |
| FR2994390B1 (fr) | 2012-08-10 | 2014-08-15 | Adocia | Procede d'abaissement de la viscosite de solutions de proteines a concentration elevee |
| CN104918957B (zh) | 2012-10-30 | 2018-11-16 | 埃派斯进有限公司 | 抗-cd40抗体及其使用方法 |
| US9856319B2 (en) | 2012-12-28 | 2018-01-02 | Abbvie Inc. | Monovalent binding proteins |
| WO2014121099A1 (en) | 2013-01-31 | 2014-08-07 | Thomas Jefferson University | Agonist fusion protein for cd40 ox40 and uses thereof |
| PL3444271T3 (pl) | 2013-08-08 | 2022-03-07 | Cytune Pharma | Modulokiny oparte na il-15 i domenie sushi il-15ralfa |
| SI3212230T1 (sl) | 2014-10-29 | 2021-08-31 | Seagen Inc. | Doziranje in dajanje ne-fukoziliranih protiteles proti-CD40 |
| CN111375066B (zh) | 2015-07-16 | 2023-04-25 | 百欧肯治疗有限公司 | 治疗癌症的组合物及方法 |
| WO2017156349A1 (en) | 2016-03-10 | 2017-09-14 | Cold Genesys, Inc. | Methods of treating solid or lymphatic tumors by combination therapy |
| FI3468997T3 (fi) | 2016-06-08 | 2023-10-31 | Xencor Inc | Igg4:ään liittyvien sairauksien hoito anti-cd19-vasta-aineilla, jotka ristisitoutuvat cd32b:een |
| WO2017220989A1 (en) | 2016-06-20 | 2017-12-28 | Kymab Limited | Anti-pd-l1 and il-2 cytokines |
| WO2018085734A1 (en) | 2016-11-04 | 2018-05-11 | Memorial Sloan Kettering Cancer Center | Bi-specific activators for tumor therapy |
| WO2018088850A2 (ko) * | 2016-11-11 | 2018-05-17 | 다이노나(주) | Cd40에 특이적으로 결합하는 항체 및 그의 용도 |
| WO2018162450A1 (en) | 2017-03-06 | 2018-09-13 | Fundación Para La Investigación Médica Aplicada | New inmunostimulatory compositions comprising an entity of cold inducible rna-binding protein with an antigen for the activation of dendritic cells |
| KR102198998B1 (ko) * | 2017-06-01 | 2021-01-07 | 서울대학교 산학협력단 | 신규한 항-cd40 항체 및 이의 용도 |
| EP3418302A1 (en) * | 2017-06-19 | 2018-12-26 | F. Hoffmann-La Roche AG | Administration routes for immune agonists |
| TW201902462A (zh) * | 2017-06-02 | 2019-01-16 | 瑞士商赫孚孟拉羅股份公司 | 用於免疫促效劑之新穎投與途徑 |
| AU2019255781A1 (en) * | 2018-04-20 | 2020-10-29 | Lyvgen Biopharma Holdings Limited | Anti-CD40 antibodies and uses thereof |
| KR20210035805A (ko) | 2018-06-15 | 2021-04-01 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 세포후 신호전달 인자의 조절을 통한 면역 활성의 증가 |
| AU2019349874A1 (en) * | 2018-09-28 | 2021-04-29 | Lyvgen Biopharma Holdings Limited | Anti-CD40 binding molecules having engineered Fc domains and therapeutic uses thereof |
| KR20210070317A (ko) | 2018-09-28 | 2021-06-14 | 리브젠 바이오파마 코., 엘티디. | 조작된 Fc 도메인을 갖는 항-CD40 결합 분자 및 그의 치료적 용도 |
| CN112839961B (zh) * | 2018-11-30 | 2023-04-04 | 江苏恒瑞医药股份有限公司 | 一种cd40抗体药物组合物及其用途 |
| US12435150B2 (en) | 2019-01-11 | 2025-10-07 | Novartis Ag | Anti-CD40 antibodies for use in treatment of hidradenitis suppurativa |
| EP3962493A2 (en) | 2019-05-03 | 2022-03-09 | Flagship Pioneering Innovations V, Inc. | Methods of modulating immune activity/level of irf or sting or of treating cancer, comprising the administration of a sting modulator and/or purinergic receptor modulator or postcellular signaling factor |
| CN119264273A (zh) | 2019-12-03 | 2025-01-07 | 埃沃特克国际有限责任公司 | 干扰素相关抗原结合蛋白及其用途 |
| US20230114107A1 (en) | 2019-12-17 | 2023-04-13 | Flagship Pioneering Innovations V, Inc. | Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly |
| EP4106819A1 (en) | 2020-02-21 | 2022-12-28 | Silverback Therapeutics, Inc. | Nectin-4 antibody conjugates and uses thereof |
| CA3185616A1 (en) * | 2020-06-04 | 2021-12-09 | Selvax Pty Ltd | Agonist anti-cd40 antibodies |
| JP2023532339A (ja) | 2020-06-29 | 2023-07-27 | フラグシップ パイオニアリング イノベーションズ ブイ,インコーポレーテッド | サノトランスミッションを促進するためにエンジニアリングされたウイルス及び癌の処置におけるそれらの使用 |
| KR20230047361A (ko) | 2020-07-01 | 2023-04-07 | 아르스 파마슈티컬스 인크. | 항-asgr1 항체 접합체 및 이의 용도 |
| WO2022037662A1 (en) * | 2020-08-21 | 2022-02-24 | Wuxi Biologics (Shanghai) Co. Ltd. | Cd40 agonistic antibody and method of use |
| JP2024512669A (ja) | 2021-03-31 | 2024-03-19 | フラグシップ パイオニアリング イノベーションズ ブイ,インコーポレーテッド | タノトランスミッションポリペプチド及び癌の処置におけるそれらの使用 |
| CA3224374A1 (en) | 2021-06-29 | 2023-01-05 | Flagship Pioneering Innovations V, Inc. | Immune cells engineered to promote thanotransmission and uses thereof |
| WO2024077191A1 (en) | 2022-10-05 | 2024-04-11 | Flagship Pioneering Innovations V, Inc. | Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer |
| WO2024151687A1 (en) | 2023-01-09 | 2024-07-18 | Flagship Pioneering Innovations V, Inc. | Genetic switches and their use in treating cancer |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5247069A (en) * | 1986-06-13 | 1993-09-21 | Oncogen | Ligands and methods for augmenting B-cell proliferation |
| JP2547556B2 (ja) * | 1987-02-06 | 1996-10-23 | 株式会社 ミドリ十字 | r−グロブリンの液状製剤 |
| SE8701004D0 (sv) | 1987-03-11 | 1987-03-11 | Astra Ab | Method for therapy of leukemias and certain other malignancies |
| JPH03204821A (ja) * | 1989-12-28 | 1991-09-06 | Green Cross Corp:The | モノクローナル抗体含有水溶液の加熱処理方法 |
| IL104684A0 (en) * | 1992-02-14 | 1993-06-10 | Bristol Myers Squibb Co | The cd40cr receptor and ligands therefor |
| AU5098493A (en) | 1992-08-21 | 1994-03-15 | Schering Corporation | Cd40 ligand, anti cd40 antibodies, and soluble cd40 |
| ATE255906T1 (de) * | 1993-10-01 | 2003-12-15 | Immunex Corp | Antikörper gegen cd40 |
| ATE267607T1 (de) * | 1993-12-23 | 2004-06-15 | Immunex Corp | Verwendung von löslichen oligomerischen cd40 liganden oder monoklonalen antikörpern zur herstellung eines arzneimitells zur vorbeugung oder behandlung von neoplastischen krankheiten |
| GB9425060D0 (en) | 1994-12-13 | 1995-02-08 | Univ Birmingham | Carcinoma treatment |
| US6267958B1 (en) * | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| EP0999853B1 (en) * | 1997-06-13 | 2003-01-02 | Genentech, Inc. | Stabilized antibody formulation |
| DK2314315T3 (en) * | 1999-06-01 | 2015-02-02 | Biogen Idec Inc | Blocking monoclonal antibody to the human alpha1-I domain of VLA-1 and their use for the treatment of inflammatory diseases |
| WO2001047554A1 (fr) * | 1999-12-28 | 2001-07-05 | Chugai Seiyaku Kabushiki Kaisha | Compositions d'anticorps stables et preparations pour injection |
| US6358670B1 (en) * | 1999-12-28 | 2002-03-19 | Electron Vision Corporation | Enhancement of photoresist plasma etch resistance via electron beam surface cure |
| EP1975182A1 (en) | 2000-02-01 | 2008-10-01 | PanGenetics B.V. | CD40-binding APC-activating molecules |
| CN1981868A (zh) * | 2000-03-31 | 2007-06-20 | 拜奥根Idec公司 | 抗细胞因子抗体或拮抗剂与抗-cd20在b细胞淋巴瘤治疗中的联合应用 |
| US6838250B2 (en) | 2000-03-31 | 2005-01-04 | Ortho-Clinical Diagnostics, Inc. | Immunoassay for C-reactive protein |
| US20030059427A1 (en) * | 2000-04-28 | 2003-03-27 | Force Walker R. | Isolation and characterization of highly active anti-CD40 antibody |
| US7063845B2 (en) * | 2000-04-28 | 2006-06-20 | Gemini Science, Inc. | Human anti-CD40 antibodies |
| US7015194B2 (en) * | 2000-05-10 | 2006-03-21 | Novo Nordisk A/S | Pharmaceutical composition comprising factor VIIa and anti-TFPI |
| WO2002028481A2 (en) * | 2000-10-02 | 2002-04-11 | Chiron Corporation | Methods of therapy for b-cell malignancies using antagonist anti-cd40 antibodies |
| ES2332402T5 (es) * | 2000-10-12 | 2018-05-14 | Genentech, Inc. | Formulaciones de proteína concentradas de viscosidad reducida |
| IL149701A0 (en) * | 2001-05-23 | 2002-11-10 | Pfizer Prod Inc | Use of anti-ctla-4 antibodies |
| JP4317010B2 (ja) * | 2001-07-25 | 2009-08-19 | ピーディーエル バイオファーマ,インコーポレイティド | IgG抗体の安定な凍結乾燥医薬製剤 |
| ATE556591T1 (de) * | 2001-11-08 | 2012-05-15 | Abbott Biotherapeutics Corp | Stabile pharmazeutische flüssigformulierung von igg-antikörpern |
| AR039067A1 (es) * | 2001-11-09 | 2005-02-09 | Pfizer Prod Inc | Anticuerpos para cd40 |
| JP2005512044A (ja) * | 2001-12-03 | 2005-04-28 | アブジェニックス・インコーポレーテッド | 結合特性に基づく抗体分類 |
| US7115108B2 (en) | 2002-04-02 | 2006-10-03 | Becton, Dickinson And Company | Method and device for intradermally delivering a substance |
| US20080009439A1 (en) * | 2002-11-05 | 2008-01-10 | Alsobrook John P | Compositions and Methods of Use for a Fibroblast Growth Factor |
| HN2004000285A (es) * | 2003-08-04 | 2006-04-27 | Pfizer Prod Inc | ANTICUERPOS DIRIGIDOS A c-MET |
-
2004
- 2004-12-02 US US11/001,980 patent/US20050136055A1/en not_active Abandoned
- 2004-12-09 SI SI200432321A patent/SI2218461T1/sl unknown
- 2004-12-09 EP EP10162787.5A patent/EP2218461B1/en not_active Expired - Lifetime
- 2004-12-09 WO PCT/IB2004/004103 patent/WO2005063289A1/en not_active Ceased
- 2004-12-09 PL PL10162787.5T patent/PL2218461T3/pl unknown
- 2004-12-09 CA CA2549652A patent/CA2549652C/en not_active Expired - Lifetime
- 2004-12-09 BR BRPI0418029A patent/BRPI0418029B8/pt not_active IP Right Cessation
- 2004-12-09 DK DK10162787.5T patent/DK2218461T3/en active
- 2004-12-09 EP EP04801378A patent/EP1706143A1/en not_active Ceased
- 2004-12-09 EP EP16164228.5A patent/EP3081933A1/en not_active Withdrawn
- 2004-12-09 HU HUE10162787A patent/HUE027717T2/en unknown
- 2004-12-09 CN CNA2004800385418A patent/CN1897971A/zh active Pending
- 2004-12-09 AU AU2004308749A patent/AU2004308749B2/en not_active Ceased
- 2004-12-09 ES ES10162787.5T patent/ES2580002T3/es not_active Expired - Lifetime
- 2004-12-09 CA CA2704300A patent/CA2704300A1/en not_active Abandoned
- 2004-12-09 RU RU2006120950/14A patent/RU2355421C2/ru active
- 2004-12-09 JP JP2006546357A patent/JP2007515469A/ja active Pending
- 2004-12-09 CN CN2012100028652A patent/CN102552905A/zh active Pending
- 2004-12-09 NZ NZ547162A patent/NZ547162A/en not_active IP Right Cessation
- 2004-12-09 KR KR1020067012364A patent/KR100847944B1/ko not_active Expired - Fee Related
- 2004-12-09 KR KR1020087004912A patent/KR20080023766A/ko not_active Ceased
- 2004-12-09 NZ NZ583179A patent/NZ583179A/en not_active IP Right Cessation
- 2004-12-21 TW TW093139794A patent/TWI359671B/zh not_active IP Right Cessation
-
2006
- 2006-05-10 IL IL175540A patent/IL175540A/en active IP Right Grant
- 2006-05-12 ZA ZA200603804A patent/ZA200603804B/en unknown
- 2006-07-20 NO NO20063373A patent/NO343797B1/no not_active IP Right Cessation
-
2009
- 2009-07-14 US US12/502,587 patent/US20090311254A1/en not_active Abandoned
- 2009-10-11 IL IL201409A patent/IL201409A0/en unknown
-
2010
- 2010-12-23 US US12/978,272 patent/US20110104182A1/en not_active Abandoned
-
2011
- 2011-04-28 JP JP2011100868A patent/JP5634321B2/ja not_active Expired - Fee Related
-
2012
- 2012-03-19 US US13/424,260 patent/US20120263732A1/en not_active Abandoned
-
2014
- 2014-06-12 JP JP2014121342A patent/JP2014205692A/ja active Pending
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