JP2005508323A5 - - Google Patents

Info

Publication number

JP2005508323A5

JP2005508323A5 JP2003530220A JP2003530220A JP2005508323A5 JP 2005508323 A5 JP2005508323 A5 JP 2005508323A5 JP 2003530220 A JP2003530220 A JP 2003530220A JP 2003530220 A JP2003530220 A JP 2003530220A JP 2005508323 A5 JP2005508323 A5 JP 2005508323A5

Authority

JP

Japan

Prior art keywords

ifn

pharmaceutical composition

paclitaxel

carboplatin

chemotherapy

Prior art date

2002-09-26

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

• Espacenet
• Global Dossier
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• BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 14
• 239000008194 pharmaceutical composition Substances 0.000 claims 12
• 229930012538 Paclitaxel Natural products 0.000 claims 11
• 229960001592 paclitaxel Drugs 0.000 claims 11
• RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 11
• 229960004562 carboplatin Drugs 0.000 claims 9
• 190000008236 carboplatin Chemical compound 0.000 claims 9
• 238000002512 chemotherapy Methods 0.000 claims 9
• 229940123237 Taxane Drugs 0.000 claims 7
• 150000001875 compounds Chemical class 0.000 claims 7
• 229910052697 platinum Inorganic materials 0.000 claims 7
• DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 claims 7
• 102100037850 Interferon gamma Human genes 0.000 claims 5
• 108010074328 Interferon-gamma Proteins 0.000 claims 5
• 206010028980 Neoplasm Diseases 0.000 claims 4
• 201000011510 cancer Diseases 0.000 claims 4
• 230000003442 weekly effect Effects 0.000 claims 3
• FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 2
• 229930195725 Mannitol Natural products 0.000 claims 2
• ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 claims 2
• 206010033128 Ovarian cancer Diseases 0.000 claims 2
• 206010061535 Ovarian neoplasm Diseases 0.000 claims 2
• DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 claims 2
• 229960004316 cisplatin Drugs 0.000 claims 2
• 229960003668 docetaxel Drugs 0.000 claims 2
• 239000000594 mannitol Substances 0.000 claims 2
• 235000010355 mannitol Nutrition 0.000 claims 2
• 229940074404 sodium succinate Drugs 0.000 claims 2
• ZDQYSKICYIVCPN-UHFFFAOYSA-L sodium succinate (anhydrous) Chemical compound [Na+].[Na+].[O-]C(=O)CCC([O-])=O ZDQYSKICYIVCPN-UHFFFAOYSA-L 0.000 claims 2
• 229920001213 Polysorbate 20 Polymers 0.000 claims 1
• 229960001855 mannitol Drugs 0.000 claims 1
• 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 claims 1
• 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 claims 1
• 229920000136 polysorbate Polymers 0.000 claims 1
• 229950008882 polysorbate Drugs 0.000 claims 1
• 229940068977 polysorbate 20 Drugs 0.000 claims 1
• 239000008223 sterile water Substances 0.000 claims 1
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1