JP2007510671A5 - - Google Patents

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Publication number
JP2007510671A5
JP2007510671A5 JP2006538531A JP2006538531A JP2007510671A5 JP 2007510671 A5 JP2007510671 A5 JP 2007510671A5 JP 2006538531 A JP2006538531 A JP 2006538531A JP 2006538531 A JP2006538531 A JP 2006538531A JP 2007510671 A5 JP2007510671 A5 JP 2007510671A5
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JP
Japan
Prior art keywords
alkyl
heterocycle
aryl
pharmaceutical composition
independently selected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006538531A
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English (en)
Japanese (ja)
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JP2007510671A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/037084 external-priority patent/WO2005046594A2/en
Publication of JP2007510671A publication Critical patent/JP2007510671A/ja
Publication of JP2007510671A5 publication Critical patent/JP2007510671A5/ja
Pending legal-status Critical Current

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JP2006538531A 2003-11-06 2004-11-04 アスベスト関連疾患および障害の治療および管理のための、jnk阻害剤の使用方法およびそれを含む組成物 Pending JP2007510671A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51860103P 2003-11-06 2003-11-06
PCT/US2004/037084 WO2005046594A2 (en) 2003-11-06 2004-11-04 Methods of using and compositions comprising a jnk inhibitor for the treatment and management of asbestos-related diseases and disorders

Publications (2)

Publication Number Publication Date
JP2007510671A JP2007510671A (ja) 2007-04-26
JP2007510671A5 true JP2007510671A5 (https=) 2007-09-20

Family

ID=34590281

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006538531A Pending JP2007510671A (ja) 2003-11-06 2004-11-04 アスベスト関連疾患および障害の治療および管理のための、jnk阻害剤の使用方法およびそれを含む組成物

Country Status (11)

Country Link
US (1) US20070270448A1 (https=)
EP (1) EP1684690A4 (https=)
JP (1) JP2007510671A (https=)
KR (1) KR20060124610A (https=)
CN (1) CN1901903A (https=)
AU (1) AU2004288715A1 (https=)
BR (1) BRPI0416266A (https=)
CA (1) CA2544591A1 (https=)
IL (1) IL175428A0 (https=)
WO (1) WO2005046594A2 (https=)
ZA (1) ZA200603719B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010009166A1 (en) 2008-07-14 2010-01-21 Gilead Colorado, Inc. Oxindolyl inhibitor compounds
CA2729909A1 (en) 2008-07-14 2010-01-21 Gilead Sciences, Inc. Imidazolyl pyrimidine inhibitor compounds
US8124764B2 (en) 2008-07-14 2012-02-28 Gilead Sciences, Inc. Fused heterocyclyc inhibitor compounds
CN102123987A (zh) 2008-07-28 2011-07-13 吉里德科学公司 亚环烷基和亚杂环烷基组蛋白脱乙酰酶抑制剂化合物
US20100183633A1 (en) * 2008-12-04 2010-07-22 University Of Massachusetts Interleukin 6 and tumor necrosis factor alpha as biomarkers of jnk inhibition
US8283357B2 (en) 2009-06-08 2012-10-09 Gilead Sciences, Inc. Cycloalkylcarbamate benzamide aniline HDAC inhibitor compounds
KR20120031170A (ko) 2009-06-08 2012-03-30 길리애드 사이언시즈, 인코포레이티드 알카노일아미노 벤즈아미드 아닐린 hdac 저해제 화합물
CA3032972A1 (en) * 2016-08-19 2018-02-22 Memorial Sloan-Kettering Cancer Center Methods of differentiating stem cells into endoderm
CN113698408B (zh) * 2020-05-22 2025-07-25 武汉朗来科技发展有限公司 Jnk抑制剂、其药物组合物和用途

Family Cites Families (23)

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US3095415A (en) * 1958-05-30 1963-06-25 Ciba Ltd Anthraquinone dyestuffs containing a 2-chloro, 4-hydroxy (lower) alkylamino, triazinylamino group
CH428043A (fr) * 1965-08-16 1967-01-15 Sandoz Ag Procédé de fabrication de colorants de dispersion isothiazolantroniques
US3541110A (en) * 1967-01-20 1970-11-17 American Home Prod Indazole-5-sulfonamides
JPS63184364A (ja) * 1987-01-27 1988-07-29 Toshiba Corp 半導体装置の製造方法
CN1137680C (zh) * 1995-09-19 2004-02-11 藤泽药品工业株式会社 气雾剂组合物
GB9622363D0 (en) * 1996-10-28 1997-01-08 Celltech Therapeutics Ltd Chemical compounds
AU6870098A (en) * 1997-03-31 1998-10-22 Du Pont Merck Pharmaceutical Company, The Indazoles of cyclic ureas useful as hiv protease inhibitors
US7507705B2 (en) * 1997-10-02 2009-03-24 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Methods for the modulation of neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections
GB9918035D0 (en) * 1999-07-30 1999-09-29 Novartis Ag Organic compounds
US20040072888A1 (en) * 1999-08-19 2004-04-15 Bennett Brydon L. Methods for treating inflammatory conditions or inhibiting JNK
KR20080028516A (ko) * 1999-08-19 2008-03-31 시그널 파머슈티컬스 인크 Jnk억제제로서의 피라졸로안트론과 그 유도체 및 이를함유하는 조성물
YU54202A (sh) * 2000-01-18 2006-01-16 Agouron Pharmaceuticals Inc. Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
US6897231B2 (en) * 2000-07-31 2005-05-24 Signal Pharmaceuticals, Inc. Indazole derivatives as JNK inhibitors and compositions and methods related thereto
US20050009876A1 (en) * 2000-07-31 2005-01-13 Bhagwat Shripad S. Indazole compounds, compositions thereof and methods of treatment therewith
US7211594B2 (en) * 2000-07-31 2007-05-01 Signal Pharmaceuticals, Llc Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith
US7429599B2 (en) * 2000-12-06 2008-09-30 Signal Pharmaceuticals, Llc Methods for treating or preventing an inflammatory or metabolic condition or inhibiting JNK
US7122544B2 (en) * 2000-12-06 2006-10-17 Signal Pharmaceuticals, Llc Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto
US7129242B2 (en) * 2000-12-06 2006-10-31 Signal Pharmaceuticals, Llc Anilinopyrimidine derivatives as JNK pathway inhibitors and compositions and methods related thereto
BR0116452A (pt) * 2000-12-21 2003-09-30 Glaxo Group Ltd Composto, composição farmacêutica, uso de um composto
US6987184B2 (en) * 2001-02-15 2006-01-17 Signal Pharmaceuticals, Llc Isothiazoloanthrones, isoxazoloanthrones, isoindolanthrones and derivatives thereof as JNK inhibitors and compositions and methods related
WO2003075917A1 (en) * 2002-03-08 2003-09-18 Signal Pharmaceuticals, Inc. Combination therapy for treating, preventing or managing proliferative disorders and cancers
US6962940B2 (en) * 2002-03-20 2005-11-08 Celgene Corporation (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
US20060004043A1 (en) * 2003-11-19 2006-01-05 Bhagwat Shripad S Indazole compounds and methods of use thereof

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