JP2007509982A - 血漿コレシストキニン(cck)濃度を制御するための非膵臓プロテアーゼおよび痛みを処置するための非膵臓プロテアーゼ - Google Patents
血漿コレシストキニン(cck)濃度を制御するための非膵臓プロテアーゼおよび痛みを処置するための非膵臓プロテアーゼ Download PDFInfo
- Publication number
- JP2007509982A JP2007509982A JP2006538382A JP2006538382A JP2007509982A JP 2007509982 A JP2007509982 A JP 2007509982A JP 2006538382 A JP2006538382 A JP 2006538382A JP 2006538382 A JP2006538382 A JP 2006538382A JP 2007509982 A JP2007509982 A JP 2007509982A
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- Prior art keywords
- protease
- mammal
- pancreatic
- cck
- administration
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Nutrition Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51555203P | 2003-10-29 | 2003-10-29 | |
| US52749003P | 2003-12-05 | 2003-12-05 | |
| PCT/US2004/036228 WO2005042012A1 (en) | 2003-10-29 | 2004-10-29 | Non-pancreatic proteases for controlling plasma cholecystokinin (cck) concentration and for treating pain |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007509982A true JP2007509982A (ja) | 2007-04-19 |
| JP2007509982A5 JP2007509982A5 (https=) | 2007-11-15 |
Family
ID=34556008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006538382A Pending JP2007509982A (ja) | 2003-10-29 | 2004-10-29 | 血漿コレシストキニン(cck)濃度を制御するための非膵臓プロテアーゼおよび痛みを処置するための非膵臓プロテアーゼ |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7459155B2 (https=) |
| EP (1) | EP1682168B1 (https=) |
| JP (1) | JP2007509982A (https=) |
| KR (1) | KR20060127857A (https=) |
| AU (1) | AU2004285558A1 (https=) |
| CA (1) | CA2544156C (https=) |
| ES (1) | ES2421538T3 (https=) |
| IL (1) | IL175210A (https=) |
| WO (1) | WO2005042012A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007222169A (ja) * | 2006-02-24 | 2007-09-06 | Dade Behring Marburg Gmbh | セリンエンドペプチダーゼの安定化調製物、その製造および使用 |
| JP2013505255A (ja) * | 2009-09-17 | 2013-02-14 | アプタリス ファーマテク,インコーポレイテッド | 膵炎及び膵不全を治療するための膵酵素組成物及び方法 |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1319655B1 (it) | 2000-11-15 | 2003-10-23 | Eurand Int | Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione. |
| US20090175842A1 (en) * | 2006-07-11 | 2009-07-09 | Chandrakant Laxminarayan Rathi | Dietary anti-bacterial compositions |
| US8246950B2 (en) | 2007-02-20 | 2012-08-21 | Aptalis Pharma Limited | Stable digestive enzyme compositions |
| WO2009109856A2 (en) | 2008-03-07 | 2009-09-11 | Axcan Pharma Inc. | Method for detecting infectious parvovirus in pharmaceutical preparations |
| KR20130072201A (ko) | 2010-03-30 | 2013-07-01 | 피페넥스 인크. | 재조합 독소 단백질의 고수준 발현 |
| UA111726C2 (uk) | 2010-10-01 | 2016-06-10 | Апталіс Фарма Лімітед | Препарат панкреліпази низької сили з кишковорозчинним покриттям |
| AU2012253379A1 (en) | 2011-05-12 | 2013-11-21 | Healthpoint, Ltd. | Wound debridement compositions containing seaprose and methods of wound treatment using same |
| CA2843556A1 (en) | 2011-08-08 | 2013-02-14 | Aptalis Pharma Ltd. | Method for dissolution testing of solid compositions containing digestive enzymes |
| US20130156884A1 (en) * | 2011-12-19 | 2013-06-20 | Triarco Industries | Protease enzymes for increased protein digestion rate and absorption and methods of using the same |
| WO2013122979A1 (en) | 2012-02-15 | 2013-08-22 | Chirhoclin, Inc. | Methods for treating pain associated with chronic pancreatitis |
| MX2014013745A (es) | 2012-05-11 | 2016-05-05 | Smith & Nephew Inc | Uso de seaprose para eliminar la pelicula biologica bacteriana. |
| US11406718B2 (en) | 2012-05-29 | 2022-08-09 | Chirhoclin, Inc. | Methods of detecting pancreobiliary ductal leaks |
| MX2016001593A (es) | 2013-08-09 | 2016-09-29 | Allergan Pharmaceuticals Int Ltd | Composicion de enzima digestiva adecuada para administracion enterica. |
| RU2016110800A (ru) | 2013-09-25 | 2017-10-30 | Пронутриа Биосайенсис, Инк. | Составы и композиции для поддержания и увеличения мышечной массы, силы и результативности, и способы их производства и использования |
| JP2017519490A (ja) | 2014-06-19 | 2017-07-20 | アプタリス ファルマ リミテッド | 膵臓抽出物からのウイルス汚染の除去方法 |
| CA3031866A1 (en) | 2016-07-27 | 2018-02-01 | Smith & Nephew, Inc. | Use of thermolysin to reduce or eliminate bacterial biofilms from surfaces |
| WO2018140707A1 (en) | 2017-01-30 | 2018-08-02 | Smith & Nephew, Inc. | Synergistic combination of thermolysin and an antibacterial agent to reduce eliminate bacterial biofilms from surfaces |
| US11744878B2 (en) | 2020-08-19 | 2023-09-05 | Chirhoclin, Inc. | Methods for treatment of COVID-19 syndrome |
| US20240315972A1 (en) | 2021-07-12 | 2024-09-26 | Zidkiyahu Simenhaus | Protein containing bio-active compositions comprising cellulose microparticle carriers |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61293927A (ja) * | 1986-06-18 | 1986-12-24 | Kaken Pharmaceut Co Ltd | 肝臓疾患予防治療剤 |
| JPS62215533A (ja) * | 1986-03-17 | 1987-09-22 | Shigemi Fujisaki | 膠原病又は関節リウマチの予防治療剤 |
| JPH01132533A (ja) * | 1987-11-18 | 1989-05-25 | Toa Yakuhin Kogyo Kk | 動物用薬剤 |
| JPH01238538A (ja) * | 1988-03-18 | 1989-09-22 | Toa Yakuhin Kogyo Kk | 健胃消化剤 |
| WO2002036156A1 (de) * | 2000-11-02 | 2002-05-10 | Cilian Ag | Verwendung von aus ciliaten gewonnenen enzymen als verdauungsfördernde arzneimittel |
| JP2003524421A (ja) * | 2000-02-24 | 2003-08-19 | アルタス バイオロジックス インコーポレイテッド | リパーゼ含有組成物およびこれらの使用方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2129947A1 (en) | 1971-03-23 | 1972-11-03 | Amano Pharma Co Ltd | Anti-inflammatory protease prepn - from aspergillus |
| JPS5692217A (en) * | 1979-12-26 | 1981-07-25 | Kowa Co | Easily absorbable enzyme preparation |
| JPS5826822A (ja) | 1981-08-10 | 1983-02-17 | Kaken Pharmaceut Co Ltd | 慢性腎炎治療剤 |
| JPS608225A (ja) | 1983-06-29 | 1985-01-17 | Kowa Co | 腸管吸収医薬組成物 |
| JPH02292226A (ja) | 1989-05-08 | 1990-12-03 | Shigemi Fujisaki | 障害された神経細胞賦活予防治療剤 |
| US5514373A (en) | 1992-05-22 | 1996-05-07 | Harris, Jr.; Roosevelt D. | Topical preparation |
| US5628981A (en) | 1994-12-30 | 1997-05-13 | Nano Systems L.L.C. | Formulations of oral gastrointestinal diagnostic x-ray contrast agents and oral gastrointestinal therapeutic agents |
| WO1998036734A1 (en) * | 1997-02-21 | 1998-08-27 | Beth Israel Deaconess Medical Center Inc. | A novel nutritional therapy which minimizes plasma cholecystokinin (cck) levels |
| JPH1149699A (ja) | 1997-08-01 | 1999-02-23 | Masao Igarashi | 女性慢性下腹疼痛症候群治療剤 |
| US6413512B1 (en) | 1998-02-13 | 2002-07-02 | National Enzyme Company | Composition and method for treating disease by increasing activated α2 macroglobulin in the blood and extravascular tissue |
| US6638906B1 (en) | 1999-12-13 | 2003-10-28 | Nobex Corporation | Amphiphilic polymers and polypeptide conjugates comprising same |
| AR032392A1 (es) | 2001-01-19 | 2003-11-05 | Solvay Pharm Gmbh | Mezcla de enzimas, preparado farmaceutico y utilizacion de dicho preparado. |
| US20030026794A1 (en) | 2001-07-31 | 2003-02-06 | Howard Fein | Selective enzyme treatment of skin conditions |
| US6713096B2 (en) | 2002-01-04 | 2004-03-30 | Melaleuca, Inc. | Dietary supplements and methods for treating pain and inflammation |
| US20040038874A1 (en) | 2002-08-22 | 2004-02-26 | Osemwota Omoigui | Method of treatment of persistent pain |
-
2004
- 2004-10-29 KR KR1020067010531A patent/KR20060127857A/ko not_active Withdrawn
- 2004-10-29 US US10/977,737 patent/US7459155B2/en not_active Expired - Fee Related
- 2004-10-29 JP JP2006538382A patent/JP2007509982A/ja active Pending
- 2004-10-29 ES ES04796860T patent/ES2421538T3/es not_active Expired - Lifetime
- 2004-10-29 EP EP04796860.7A patent/EP1682168B1/en not_active Expired - Lifetime
- 2004-10-29 AU AU2004285558A patent/AU2004285558A1/en not_active Abandoned
- 2004-10-29 CA CA2544156A patent/CA2544156C/en not_active Expired - Fee Related
- 2004-10-29 WO PCT/US2004/036228 patent/WO2005042012A1/en not_active Ceased
-
2006
- 2006-04-26 IL IL175210A patent/IL175210A/en not_active IP Right Cessation
-
2008
- 2008-10-24 US US12/258,122 patent/US20090081184A1/en not_active Abandoned
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62215533A (ja) * | 1986-03-17 | 1987-09-22 | Shigemi Fujisaki | 膠原病又は関節リウマチの予防治療剤 |
| JPS61293927A (ja) * | 1986-06-18 | 1986-12-24 | Kaken Pharmaceut Co Ltd | 肝臓疾患予防治療剤 |
| JPH01132533A (ja) * | 1987-11-18 | 1989-05-25 | Toa Yakuhin Kogyo Kk | 動物用薬剤 |
| JPH01238538A (ja) * | 1988-03-18 | 1989-09-22 | Toa Yakuhin Kogyo Kk | 健胃消化剤 |
| JP2003524421A (ja) * | 2000-02-24 | 2003-08-19 | アルタス バイオロジックス インコーポレイテッド | リパーゼ含有組成物およびこれらの使用方法 |
| WO2002036156A1 (de) * | 2000-11-02 | 2002-05-10 | Cilian Ag | Verwendung von aus ciliaten gewonnenen enzymen als verdauungsfördernde arzneimittel |
Non-Patent Citations (3)
| Title |
|---|
| EL-BOHY,A. ET AL: "Deafferentation-induced changes in neuropeptides of the adult rat dorsal horn following pronase inje", J COMP NEUROL, vol. 336, no. 4, JPN6010044210, 1993, pages 545 - 54, ISSN: 0001690159 * |
| VENTRUCCI,M. ET AL: "[Therapeutic effect of a pharmacologic combination of choleretics and digestive enzymes in exocrine", MINERVA MED, vol. 66, no. 17, JPN6010044209, 1975, pages 819 - 23, ISSN: 0001690157 * |
| メルクマニュアル第17版日本語版, JPN6010044212, 1999, pages 272 - 278, ISSN: 0001690158 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007222169A (ja) * | 2006-02-24 | 2007-09-06 | Dade Behring Marburg Gmbh | セリンエンドペプチダーゼの安定化調製物、その製造および使用 |
| JP2013505255A (ja) * | 2009-09-17 | 2013-02-14 | アプタリス ファーマテク,インコーポレイテッド | 膵炎及び膵不全を治療するための膵酵素組成物及び方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005042012A1 (en) | 2005-05-12 |
| CA2544156A1 (en) | 2005-05-12 |
| US7459155B2 (en) | 2008-12-02 |
| IL175210A (en) | 2014-02-27 |
| US20050158299A1 (en) | 2005-07-21 |
| EP1682168B1 (en) | 2013-05-01 |
| EP1682168A1 (en) | 2006-07-26 |
| KR20060127857A (ko) | 2006-12-13 |
| US20090081184A1 (en) | 2009-03-26 |
| IL175210A0 (en) | 2006-09-05 |
| AU2004285558A1 (en) | 2005-05-12 |
| ES2421538T3 (es) | 2013-09-03 |
| CA2544156C (en) | 2012-07-10 |
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