JP2007506780A5 - - Google Patents
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- Publication number
- JP2007506780A5 JP2007506780A5 JP2006528270A JP2006528270A JP2007506780A5 JP 2007506780 A5 JP2007506780 A5 JP 2007506780A5 JP 2006528270 A JP2006528270 A JP 2006528270A JP 2006528270 A JP2006528270 A JP 2006528270A JP 2007506780 A5 JP2007506780 A5 JP 2007506780A5
- Authority
- JP
- Japan
- Prior art keywords
- vitamin
- compound
- pharmaceutical composition
- composition according
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 229930003316 Vitamin D Natural products 0.000 claims 9
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims 9
- 239000011710 vitamin D Substances 0.000 claims 9
- 235000019166 vitamin D Nutrition 0.000 claims 9
- -1 vitamin D compound Chemical class 0.000 claims 9
- 229940046008 vitamin d Drugs 0.000 claims 9
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 6
- 206010069632 Bladder dysfunction Diseases 0.000 claims 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 4
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 2
- 239000000018 receptor agonist Substances 0.000 claims 2
- 229940044601 receptor agonist Drugs 0.000 claims 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 2
- 102000009310 vitamin D receptors Human genes 0.000 claims 2
- 108050000156 vitamin D receptors Proteins 0.000 claims 2
- 239000011647 vitamin D3 Substances 0.000 claims 2
- 229940021056 vitamin d3 Drugs 0.000 claims 2
- LRLWXBHFPGSUOX-GJQYOBCGSA-N (1r,3z,5s)-3-[(2e)-2-[(3as,7as)-1-[(e,2s)-6-ethyl-6-hydroxyoct-4-en-2-yl]-7a-methyl-3a,5,6,7-tetrahydro-3h-inden-4-ylidene]ethylidene]-5-fluoro-4-methylidenecyclohexan-1-ol Chemical compound C1(/[C@@H]2CC=C([C@]2(CCC1)C)[C@@H](C)C/C=C/C(O)(CC)CC)=C\C=C1\C[C@@H](O)C[C@H](F)C1=C LRLWXBHFPGSUOX-GJQYOBCGSA-N 0.000 claims 1
- 206010063408 Bladder hypertrophy Diseases 0.000 claims 1
- 206010020853 Hypertonic bladder Diseases 0.000 claims 1
- 208000009722 Overactive Urinary Bladder Diseases 0.000 claims 1
- 239000011612 calcitriol Substances 0.000 claims 1
- 229960005084 calcitriol Drugs 0.000 claims 1
- 235000020964 calcitriol Nutrition 0.000 claims 1
- GMRQFYUYWCNGIN-NKMMMXOESA-N calcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C GMRQFYUYWCNGIN-NKMMMXOESA-N 0.000 claims 1
- 125000001153 fluoro group Chemical group F* 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 208000020629 overactive bladder Diseases 0.000 claims 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical group C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0322395A GB0322395D0 (en) | 2003-09-24 | 2003-09-24 | Methods for treating bladder dysfunction and related compounds and compositions |
| GB0325598A GB2407499B (en) | 2003-11-03 | 2003-11-03 | Vitamin D3 analogue for use in the treatment of BPH |
| GB0404567A GB0404567D0 (en) | 2004-03-01 | 2004-03-01 | Methods for treating bladder dysfunction and related compounds and compositions |
| GB0404571A GB0404571D0 (en) | 2004-03-01 | 2004-03-01 | Methods for treating interstitial cystitis and related compounds and compositions |
| GB0416876A GB0416876D0 (en) | 2004-07-29 | 2004-07-29 | Compound and use in treatment |
| PCT/US2004/031532 WO2005030223A1 (en) | 2003-09-24 | 2004-09-24 | Methods for treating bladder dysfunction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007506780A JP2007506780A (ja) | 2007-03-22 |
| JP2007506780A5 true JP2007506780A5 (enExample) | 2007-11-08 |
Family
ID=34397209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006528270A Abandoned JP2007506780A (ja) | 2003-09-24 | 2004-09-24 | 膀胱機能障害の治療方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20070054887A1 (enExample) |
| EP (1) | EP1663250A4 (enExample) |
| JP (1) | JP2007506780A (enExample) |
| AU (1) | AU2004275845A1 (enExample) |
| BR (1) | BRPI0414701A (enExample) |
| CA (1) | CA2540325A1 (enExample) |
| IL (1) | IL174369A0 (enExample) |
| WO (1) | WO2005030223A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007525533A (ja) * | 2004-03-01 | 2007-09-06 | ビオエクセル エスピーエー | 間質性膀胱炎の治療方法、並びに関連化合物及び組成物 |
| CA2580962A1 (en) * | 2004-09-24 | 2006-04-06 | Bioxell S.P.A. | 20-cycloalkyl,26,27-alkyl/haloalkyl vitamin d3 compounds and methods of use thereof |
| EP1812011A1 (en) | 2004-11-12 | 2007-08-01 | Bioxell S.p.a. | Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer |
| JP4809931B2 (ja) * | 2007-08-23 | 2011-11-09 | セラコス・インコーポレイテッド | ベンジルベンゼン誘導体およびその使用方法 |
| US7737028B2 (en) * | 2007-09-28 | 2010-06-15 | Applied Materials, Inc. | Selective ruthenium deposition on copper materials |
| US8222236B2 (en) * | 2008-07-10 | 2012-07-17 | Wisconsin Alumni Research Foundation | 2-methylene-(20E)-20(22)-dehydro-19-nor-vitamin D analogs |
| EP2908827A4 (en) * | 2012-10-19 | 2016-08-31 | Celus Pharmaceuticals Inc | VITAMIN D ANALOGUE FOR THE TREATMENT OF A NEUROLOGICAL DISEASE |
| WO2017164195A1 (ja) * | 2016-03-24 | 2017-09-28 | ダイワボウホールディングス株式会社 | 模様付き不織布およびその製造方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5795882A (en) * | 1992-06-22 | 1998-08-18 | Bone Care International, Inc. | Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations |
| US5763429A (en) * | 1993-09-10 | 1998-06-09 | Bone Care International, Inc. | Method of treating prostatic diseases using active vitamin D analogues |
| TW403735B (en) * | 1995-11-22 | 2000-09-01 | Hoffmann La Roche | 25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol |
| US5747479A (en) * | 1996-01-03 | 1998-05-05 | Hoffmann-La Roche Inc. | Vitamin D3 analogs useful for reversing the photodamage in sun-exposed skin |
| US5939408A (en) * | 1996-05-23 | 1999-08-17 | Hoffman-La Roche Inc. | Vitamin D3 analogs |
| US6566353B2 (en) * | 1996-12-30 | 2003-05-20 | Bone Care International, Inc. | Method of treating malignancy associated hypercalcemia using active vitamin D analogues |
| US20020128240A1 (en) * | 1996-12-30 | 2002-09-12 | Bone Care International, Inc. | Treatment of hyperproliferative diseases using active vitamin D analogues |
| US6008209A (en) * | 1997-04-28 | 1999-12-28 | Hoffmann-La Roche Inc. | Method of using vitamin D3 analogs with bis C-20 side chains |
| US5872113A (en) * | 1997-05-16 | 1999-02-16 | Syntex (U.S.A.) Inc. | Fluorinated vitamin D3 analogs |
| US5811414A (en) * | 1997-05-16 | 1998-09-22 | Hoffmann-La Roche Inc. | Vitamin D3 analogs useful for reversing the photodamage in sun-exposed skin |
| US6331642B1 (en) * | 1999-07-12 | 2001-12-18 | Hoffmann-La Roche Inc. | Vitamin D3 analogs |
| JP2006525367A (ja) * | 2003-04-30 | 2006-11-09 | ビオクセル エッセ ピ ア | ジェミニビタミンｄ３化合物及びその使用方法 |
| EP1677802A2 (en) * | 2003-04-30 | 2006-07-12 | Bioxell S.p.a. | 1,3 aclyated 24-keto-vitamin d3 compounds and methods of use thereof |
-
2004
- 2004-09-24 BR BRPI0414701-4A patent/BRPI0414701A/pt not_active IP Right Cessation
- 2004-09-24 EP EP04789064A patent/EP1663250A4/en not_active Withdrawn
- 2004-09-24 WO PCT/US2004/031532 patent/WO2005030223A1/en not_active Ceased
- 2004-09-24 CA CA002540325A patent/CA2540325A1/en not_active Abandoned
- 2004-09-24 US US10/573,164 patent/US20070054887A1/en not_active Abandoned
- 2004-09-24 JP JP2006528270A patent/JP2007506780A/ja not_active Abandoned
- 2004-09-24 AU AU2004275845A patent/AU2004275845A1/en not_active Abandoned
-
2006
- 2006-03-16 IL IL174369A patent/IL174369A0/en unknown
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