JP2007505138A - 末端に連結された二環糖部分を有する、ギャップ化オリゴマー化合物 - Google Patents

末端に連結された二環糖部分を有する、ギャップ化オリゴマー化合物 Download PDF

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JP2007505138A
JP2007505138A JP2006526330A JP2006526330A JP2007505138A JP 2007505138 A JP2007505138 A JP 2007505138A JP 2006526330 A JP2006526330 A JP 2006526330A JP 2006526330 A JP2006526330 A JP 2006526330A JP 2007505138 A JP2007505138 A JP 2007505138A
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oligomeric compound
independently
oligonucleotide
rna
nucleoside
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JP2007505138A5 (enExample
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スウェイジ，エリック・イー
ミガワ，マイケル・ティー
ウィルシキーヴィッツ，タデウシュ・クリシュトフ
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Ionis Pharmaceuticals Inc
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Isis Pharmaceuticals Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2006526330A 2003-09-09 2004-09-09 末端に連結された二環糖部分を有する、ギャップ化オリゴマー化合物 Pending JP2007505138A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US50171903P 2003-09-09 2003-09-09
US56803904P 2004-05-03 2004-05-03
US56848904P 2004-05-06 2004-05-06
US10/872,106 US20050053981A1 (en) 2003-09-09 2004-06-18 Gapped oligomeric compounds having linked bicyclic sugar moieties at the termini
PCT/US2004/029650 WO2005023825A2 (en) 2003-09-09 2004-09-09 Gapped oligomeric compounds having linked bicyclic sugar moieties at the termini

Publications (2)

Publication Number Publication Date
JP2007505138A true JP2007505138A (ja) 2007-03-08
JP2007505138A5 JP2007505138A5 (enExample) 2007-10-25

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JP2006526330A Pending JP2007505138A (ja) 2003-09-09 2004-09-09 末端に連結された二環糖部分を有する、ギャップ化オリゴマー化合物

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US (2) US20050053981A1 (enExample)
EP (1) EP1670810A4 (enExample)
JP (1) JP2007505138A (enExample)
AU (1) AU2004270741B2 (enExample)
CA (1) CA2538174A1 (enExample)
WO (1) WO2005023825A2 (enExample)

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