JP2007502123A - 改善されたハロヒドリンデハロゲナーゼおよび関連するポリヌクレオチド - Google Patents
改善されたハロヒドリンデハロゲナーゼおよび関連するポリヌクレオチド Download PDFInfo
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- JP2007502123A JP2007502123A JP2006523447A JP2006523447A JP2007502123A JP 2007502123 A JP2007502123 A JP 2007502123A JP 2006523447 A JP2006523447 A JP 2006523447A JP 2006523447 A JP2006523447 A JP 2006523447A JP 2007502123 A JP2007502123 A JP 2007502123A
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| WO2008042876A2 (en) | 2006-10-02 | 2008-04-10 | Codexis, Inc. | Compositions and methods for producing stereoisomerically pure statins and synthetic intermediates therefor |
| JP2010536385A (ja) | 2007-08-24 | 2010-12-02 | コデクシス， インコーポレイテッド | （ｒ）−３−ヒドロキシチオランの立体選択的生成のための改善されたケトレダクターゼポリペプチド |
| US20090312196A1 (en) | 2008-06-13 | 2009-12-17 | Codexis, Inc. | Method of synthesizing polynucleotide variants |
| DK3023494T3 (en) | 2008-06-13 | 2019-02-25 | Codexis Inc | PROCEDURE FOR SYNTHESIS OF POLYNUCLEOTIDE VARIETIES |
| EP2329013B1 (en) | 2008-08-27 | 2015-10-28 | Codexis, Inc. | Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine |
| US8288131B2 (en) * | 2008-08-27 | 2012-10-16 | Codexis, Inc. | Ketoreductase polypeptides and uses thereof |
| WO2010080635A2 (en) * | 2008-12-18 | 2010-07-15 | Codexis, Inc. | Recombinant halohydrin dehalogenase polypeptides |
| JP5707344B2 (ja) | 2009-02-26 | 2015-04-30 | コデクシス， インコーポレイテッド | トランスアミナーゼ生体触媒 |
| SG177331A1 (en) | 2009-06-22 | 2012-02-28 | Codexis Inc | Ketoreductase-mediated stereoselective route to alpha chloroalcohols |
| WO2011005477A1 (en) | 2009-06-22 | 2011-01-13 | Codexis, Inc. | Transaminase reactions |
| US20110082055A1 (en) * | 2009-09-18 | 2011-04-07 | Codexis, Inc. | Reduced codon mutagenesis |
| DK3301208T3 (da) | 2009-09-18 | 2020-12-14 | Codexis Inc | Reduceret codon-mutagenese |
| CN102884178B (zh) | 2009-12-08 | 2014-12-03 | 科德克希思公司 | 拉唑化合物的合成 |
| HUE026367T2 (en) | 2010-05-04 | 2016-06-28 | Codexis Inc | Biocatalysts for ezetimibe synthesis |
| EP2606139B1 (en) | 2010-08-16 | 2015-07-15 | Codexis, Inc. | Biocatalysts and methods for the synthesis of (1r,2r)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine |
| EP2649187B1 (en) | 2010-12-08 | 2017-11-22 | Codexis, Inc. | Biocatalysts and methods for the synthesis of armodafinil |
| HUE038800T2 (hu) | 2011-04-13 | 2018-11-28 | Codexis Inc | Biokatalitikus eljárás eszlikarbazepin és ennek analógjai elõállítására |
| IN2014CN04470A (https=) | 2011-11-18 | 2015-09-04 | Codexis Inc | |
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| CN104372038A (zh) * | 2013-08-12 | 2015-02-25 | 南京朗恩生物科技有限公司 | 两步催化制备(r)-4-氰基-3-羟基丁酸乙酯的方法 |
| CN106232619B (zh) | 2013-11-13 | 2022-09-09 | 科德克希思公司 | 工程化的亚胺还原酶和用于酮和胺化合物的还原胺化的方法 |
| US10370648B2 (en) | 2014-11-25 | 2019-08-06 | Codexis, Inc. | Engineered imine reductases and methods for the reductive amination of ketone and amine compounds |
| WO2016130412A1 (en) | 2015-02-10 | 2016-08-18 | Codexis, Inc. | Ketoreductase polypeptides for the synthesis of chiral compounds |
| CN104745557B (zh) * | 2015-03-05 | 2017-09-22 | 浙江工业大学 | 来源于嗜清洁细小杆菌卤醇脱卤酶突变体及其应用 |
| EP3093337A3 (en) | 2015-05-13 | 2017-03-15 | Samsung Electronics Co., Ltd. | Microorganism including gene encoding protein having hydroxylase activity and method of reducing concentration of fluorinated methane in sample using the same |
| EP3178922B1 (en) | 2015-12-07 | 2019-05-22 | Samsung Electronics Co., Ltd. | Bacterial cytochrome p450 protein variant and method of reducing concentration of fluorinated methane in sample using the same |
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| CN109295044A (zh) * | 2018-10-26 | 2019-02-01 | 浙江大学 | 一种卤醇脱卤酶突变体及其应用 |
| WO2020093142A1 (en) * | 2018-11-07 | 2020-05-14 | The Royal Institution For The Advancement Of Learning/Mcgill University | Testosterone-inducing peptide compounds and associated combinations |
| CN120981566A (zh) | 2023-01-12 | 2025-11-18 | 诺华股份有限公司 | 工程化酮还原酶多肽 |
| CN119530210B (zh) * | 2024-11-12 | 2025-10-03 | 南京师范大学 | 卤醇脱卤酶突变体及编码基因、重组载体、重组菌株、酶制剂和应用 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008108466A1 (ja) * | 2007-03-07 | 2008-09-12 | Mitsubishi Rayon Co., Ltd. | 改良型ハロヒドリンエポキシダーゼ |
| CN101636497B (zh) * | 2007-03-07 | 2013-05-22 | 三菱丽阳株式会社 | 改良型卤代醇环氧酶 |
| US8637272B2 (en) | 2007-03-07 | 2014-01-28 | Mitsubishi Rayon Co., Ltd. | Halohydrin epoxidase |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005017141A1 (en) | 2005-02-24 |
| US8101395B2 (en) | 2012-01-24 |
| US20100167345A1 (en) | 2010-07-01 |
| CA2535255A1 (en) | 2005-02-24 |
| EP1654356A1 (en) | 2006-05-10 |
| SG148180A1 (en) | 2008-12-31 |
| MXPA06001725A (es) | 2006-04-27 |
| NO20060405L (no) | 2006-03-10 |
| IL173261A0 (en) | 2006-06-11 |
| US8535910B2 (en) | 2013-09-17 |
| US20050153417A1 (en) | 2005-07-14 |
| US7824898B2 (en) | 2010-11-02 |
| US20120208259A1 (en) | 2012-08-16 |
| BRPI0413501A (pt) | 2006-10-10 |
| KR20060064617A (ko) | 2006-06-13 |
| AU2004265693A1 (en) | 2005-02-24 |
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