|
TWI329105B
(en)
*
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
|
ES2445208T3
(es)
*
|
2002-07-29 |
2014-02-28 |
Rigel Pharmaceuticals, Inc. |
Compuestos de 2,4-pirimidindiamina para uso en métodos para tratar o prevenir enfermedades autoinmunitarias
|
|
BRPI0413018B8
(pt)
|
2003-07-30 |
2021-05-25 |
Rigel Pharmaceuticals Inc |
composto, e, uso de um composto
|
|
WO2005013996A2
(en)
|
2003-08-07 |
2005-02-17 |
Rigel Pharmaceuticals, Inc. |
2,4-pyrimidinediamine compounds and uses as anti-proliferative agents
|
|
NZ585188A
(en)
*
|
2003-08-15 |
2011-09-30 |
Novartis Ag |
2,4-Pyrimidinediamines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders
|
|
MXPA06003054A
(es)
*
|
2003-09-18 |
2006-05-31 |
Novartis Ag |
2,4-di-(fenil-amino)-pirimidinas utiles en el tratamiento de trastornos proliferativos.
|
|
EP1763514A2
(en)
*
|
2004-05-18 |
2007-03-21 |
Rigel Pharmaceuticals, Inc. |
Cycloalkyl substituted pyrimidinediamine compounds and their uses
|
|
GB2420559B
(en)
*
|
2004-11-15 |
2008-08-06 |
Rigel Pharmaceuticals Inc |
Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses
|
|
EP1814878B1
(en)
*
|
2004-11-24 |
2012-01-04 |
Rigel Pharmaceuticals, Inc. |
Spiro-2, 4-pyrimidinediamine compounds and their uses
|
|
DE602006010979D1
(de)
|
2005-01-19 |
2010-01-21 |
Rigel Pharmaceuticals Inc |
Prodrugs aus 2,4-pyrimidindiamin-verbindungen und ihre verwendungen
|
|
US8227455B2
(en)
*
|
2005-04-18 |
2012-07-24 |
Rigel Pharmaceuticals, Inc. |
Methods of treating cell proliferative disorders
|
|
AU2006241825A1
(en)
|
2005-04-28 |
2006-11-09 |
Mitsubishi Tanabe Pharma Corporation |
Cyanopyridine derivative and use thereof as medicine
|
|
EP1883302A4
(en)
*
|
2005-05-03 |
2009-05-20 |
Rigel Pharmaceuticals Inc |
JAK KINASE HEMMER AND ITS USE
|
|
US20070203161A1
(en)
|
2006-02-24 |
2007-08-30 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
WO2006133426A2
(en)
|
2005-06-08 |
2006-12-14 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
US7417066B2
(en)
|
2005-06-08 |
2008-08-26 |
Schering Ag |
Inhibitors of soluble adenylate cyclase
|
|
DE102005027274A1
(de)
*
|
2005-06-08 |
2006-12-14 |
Schering Ag |
Inhibitoren der löslichen Adenylatzyklase
|
|
EP1896134A2
(en)
|
2005-06-13 |
2008-03-12 |
Rigel Pharmaceuticals, Inc. |
Methods and compositions for treating degenerative bone disorders
|
|
PL1734251T3
(pl)
*
|
2005-06-17 |
2007-05-31 |
Magneti Marelli Powertrain Spa |
Wtryskiwacz paliwa
|
|
MX2008000574A
(es)
*
|
2005-07-11 |
2008-03-14 |
Sanofi Aventis |
Nuevos derivados de 2,4-dianilinopirimidinas, la preparacion de los mismos, su uso como medicamentos, composiciones farmaceuticas y, en particular, como inhibidores ikk.
|
|
FR2888239B1
(fr)
*
|
2005-07-11 |
2008-05-09 |
Sanofi Aventis Sa |
Nouveaux derives de 2,4-dianilinopyrimidines, leur preparation, a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk
|
|
CA2626789A1
(en)
|
2005-10-21 |
2007-04-26 |
Exelixis, Inc. |
Pyrimidinones as casein kinase ii (ck2) modulators
|
|
ES2439948T3
(es)
*
|
2006-02-17 |
2014-01-27 |
Rigel Pharmaceuticals, Inc. |
Compuestos de 2,4-pirimidindiamina para el tratamiento o la prevención de enfermedades autoinmunitarias
|
|
CA2642229C
(en)
|
2006-02-24 |
2015-05-12 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
PE20120006A1
(es)
*
|
2006-05-15 |
2012-02-02 |
Boehringer Ingelheim Int |
Compuestos derivados de pirimidina como inhibidores de la quinasa aurora
|
|
WO2007146977A1
(en)
|
2006-06-15 |
2007-12-21 |
Boehringer Ingelheim International Gmbh |
2-anilino-4-aminoalkyleneaminopyrimidines
|
|
RU2008152195A
(ru)
|
2006-06-15 |
2010-07-20 |
БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) |
2-анилино-4-(гетероциклил)аминопиримидины, как ингибиторы протеинкиназы с-альфа
|
|
ES2528797T3
(es)
|
2006-08-21 |
2015-02-12 |
Genentech, Inc. |
Compuestos de aza-benzotiofenilo y métodos de uso
|
|
CN101535276B
(zh)
|
2006-10-23 |
2013-08-28 |
赛福伦公司 |
作为ALK和c-MET抑制剂的2,4-二氨基嘧啶稠合双环衍生物
|
|
WO2008061201A1
(en)
*
|
2006-11-15 |
2008-05-22 |
Rigel Pharmaceuticals, Inc. |
Methods for treating renal tumors using 2,4-pyrimidinediamine drug and prodrug compounds
|
|
EP2311807B1
(en)
|
2006-12-08 |
2015-11-11 |
Novartis AG |
Compounds and composition as protein kinase inhibitors
|
|
CA2670645A1
(en)
*
|
2006-12-19 |
2008-07-03 |
Genentech, Inc. |
Pyrimidine kinase inhibitors
|
|
WO2008077885A2
(en)
*
|
2006-12-22 |
2008-07-03 |
Boehringer Ingelheim International Gmbh |
2- [(phenylamino) -pyrimidin-4ylamin0] -cyclopentane carboxamide derivatives and related compounds as inhibitors of kinases of the cell cycle for the treatment of cancer
|
|
EP2097376A2
(en)
|
2006-12-22 |
2009-09-09 |
F. Hoffmann-Roche AG |
Spiro-piperidine derivatives
|
|
DE102007010801A1
(de)
|
2007-03-02 |
2008-09-04 |
Bayer Cropscience Ag |
Diaminopyrimidine als Fungizide
|
|
WO2008118823A2
(en)
*
|
2007-03-26 |
2008-10-02 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
KR101511074B1
(ko)
|
2007-04-16 |
2015-04-13 |
애브비 인코포레이티드 |
7-치환된 인돌 Mcl-1 억제제
|
|
US20090012045A1
(en)
*
|
2007-06-26 |
2009-01-08 |
Rigel Pharmaceuticals, Inc. |
Methods of Treating Cell Proliferative Disorders
|
|
CA2693594A1
(en)
|
2007-07-17 |
2009-01-22 |
Rigel Pharmaceuticals, Inc. |
Cyclic amine substituted pyrimidinediamines as pkc inhibitors
|
|
ES2375919T3
(es)
|
2008-01-11 |
2012-03-07 |
F. Hoffmann-La Roche Ag |
Moduladores de beta-amiloide.
|
|
MX2010008700A
(es)
*
|
2008-02-22 |
2010-08-30 |
Hoffmann La Roche |
Moduladores de beta-amiloide.
|
|
US20100155402A1
(en)
*
|
2008-02-27 |
2010-06-24 |
Pwp Industries, Inc. |
Display and storage container
|
|
US8592432B2
(en)
|
2008-04-07 |
2013-11-26 |
Bei Chen |
Compounds and compositions as protein kinase inhibitors
|
|
US9273077B2
(en)
|
2008-05-21 |
2016-03-01 |
Ariad Pharmaceuticals, Inc. |
Phosphorus derivatives as kinase inhibitors
|
|
PT2300013T
(pt)
|
2008-05-21 |
2017-10-31 |
Ariad Pharma Inc |
Derivados de fósforo como inibidores de cinases
|
|
EA201100078A1
(ru)
*
|
2008-06-25 |
2011-08-30 |
Айрм Ллк |
Производные пиримидина в качестве ингибиторов киназы
|
|
US8338439B2
(en)
|
2008-06-27 |
2012-12-25 |
Celgene Avilomics Research, Inc. |
2,4-disubstituted pyrimidines useful as kinase inhibitors
|
|
TWI546290B
(zh)
|
2008-06-27 |
2016-08-21 |
賽基艾維洛米斯研究股份有限公司 |
雜芳基化合物及其用途
|
|
US11351168B1
(en)
|
2008-06-27 |
2022-06-07 |
Celgene Car Llc |
2,4-disubstituted pyrimidines useful as kinase inhibitors
|
|
AU2013202496B2
(en)
*
|
2008-06-27 |
2016-08-04 |
Celgene Car Llc |
Heteroaryl compounds and uses thereof
|
|
MX2010014565A
(es)
|
2008-07-01 |
2011-03-04 |
Genentech Inc |
Isoindolona y metodos de uso.
|
|
RU2509078C2
(ru)
|
2008-07-01 |
2014-03-10 |
Дженентек, Инк. |
Бициклические гетероциклы в качестве ингибиторов киназы мек
|
|
EP2161259A1
(de)
|
2008-09-03 |
2010-03-10 |
Bayer CropScience AG |
4-Halogenalkylsubstituierte Diaminopyrimidine als Fungizide
|
|
ES2429517T3
(es)
|
2008-10-09 |
2013-11-15 |
F. Hoffmann-La Roche Ag |
Moduladores para la beta amiloide
|
|
CN102209537A
(zh)
|
2008-11-10 |
2011-10-05 |
弗·哈夫曼-拉罗切有限公司 |
杂环γ分泌酶调节剂
|
|
RU2535032C2
(ru)
|
2008-12-22 |
2014-12-10 |
Милленниум Фармасьютикалз, Инк. |
Сочетание ингибиторов аврора киназы и анти-cd 20 антител
|
|
ES2624622T3
(es)
|
2008-12-30 |
2017-07-17 |
Rigel Pharmaceuticals, Inc. |
Inhibidores de pirimidindiamina cinasa
|
|
WO2010083240A2
(en)
*
|
2009-01-14 |
2010-07-22 |
Rigel Pharmaceuticals, Inc. |
Methods for treating inflammatory disorders using 2,4-pyrimidinediamine compounds
|
|
ES2555982T3
(es)
*
|
2009-01-15 |
2016-01-12 |
Rigel Pharmaceuticals, Inc. |
Inhibidores de la proteína quinasa C y usos de los mismos
|
|
CA2749837C
(en)
|
2009-01-21 |
2017-07-11 |
Rigel Pharmaceuticals, Inc. |
Derivatives of n2-(3-pyridil or phenyl)-n4-(4-piperidyl)-2,4-pyrimidinediamine useful in the treatment of inflammatory, autoimmune or proliferative diseases
|
|
US20110071158A1
(en)
*
|
2009-03-18 |
2011-03-24 |
Boehringer Ingelheim International Gmbh |
New compounds
|
|
KR101705158B1
(ko)
|
2009-05-05 |
2017-02-09 |
다나-파버 캔서 인스티튜트 인크. |
Egfr 억제제 및 질환 치료방법
|
|
CN102470135A
(zh)
*
|
2009-07-28 |
2012-05-23 |
里格尔药品股份有限公司 |
抑制jak途径的组合物和方法
|
|
KR101726444B1
(ko)
*
|
2009-08-31 |
2017-04-12 |
스미또모 가가꾸 가부시키가이샤 |
수지, 레지스트 조성물 및 레지스트 패턴의 제조 방법
|
|
ES2524127T3
(es)
|
2009-11-20 |
2014-12-04 |
Rigel Pharmaceuticals, Inc. |
Compuestos de 2,4-pirimidinodiamina y sus profármacos y sus usos
|
|
US20110130415A1
(en)
|
2009-12-01 |
2011-06-02 |
Rajinder Singh |
Protein kinase c inhibitors and uses thereof
|
|
US8486096B2
(en)
*
|
2010-02-11 |
2013-07-16 |
Ethicon Endo-Surgery, Inc. |
Dual purpose surgical instrument for cutting and coagulating tissue
|
|
US8486967B2
(en)
|
2010-02-17 |
2013-07-16 |
Hoffmann-La Roche Inc. |
Heteroaryl substituted piperidines
|
|
CA2792278C
(en)
|
2010-04-13 |
2019-05-14 |
Rigel Pharmaceuticals, Inc. |
2,4-pyrimidinediamine compounds and prodrugs thereof and their uses
|
|
US8927547B2
(en)
*
|
2010-05-21 |
2015-01-06 |
Noviga Research Ab |
Pyrimidine derivatives
|
|
EP2395001A1
(en)
*
|
2010-05-21 |
2011-12-14 |
Chemilia AB |
Novel pyrimidine derivatives
|
|
PT2576541T
(pt)
|
2010-06-04 |
2016-07-08 |
Hoffmann La Roche |
Derivados de aminopirimidina como moduladores de lrrk2
|
|
EP2595982B1
(en)
|
2010-07-21 |
2018-06-13 |
Rigel Pharmaceuticals, Inc. |
Protein kinase c inhibitors and uses thereof
|
|
KR101841000B1
(ko)
|
2010-07-28 |
2018-03-22 |
스미또모 가가꾸 가부시키가이샤 |
포토레지스트 조성물
|
|
CN105566229A
(zh)
|
2010-08-10 |
2016-05-11 |
西建阿维拉米斯研究公司 |
Btk抑制剂的苯磺酸盐及其用途和制备方法
|
|
JP6195692B2
(ja)
|
2010-08-30 |
2017-09-13 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法並びに新規化合物及び樹脂
|
|
EP2635285B1
(en)
|
2010-11-01 |
2017-05-03 |
Celgene Avilomics Research, Inc. |
Heteroaryl compounds and uses thereof
|
|
MX382354B
(es)
|
2010-11-01 |
2025-03-13 |
Celgene Car Llc |
Compuestos heterocíclicos y usos de los mismos.
|
|
HRP20172006T1
(hr)
|
2010-11-10 |
2018-02-09 |
Genentech, Inc. |
Derivati pirazol-aminopiridina kao lrrk2-modulatori
|
|
JP5957003B2
(ja)
|
2010-11-10 |
2016-07-27 |
セルジーン アヴィロミクス リサーチ, インコーポレイテッド |
変異体選択的egfr阻害剤およびその使用
|
|
EP2489663A1
(en)
|
2011-02-16 |
2012-08-22 |
Almirall, S.A. |
Compounds as syk kinase inhibitors
|
|
JP5829939B2
(ja)
|
2011-02-25 |
2015-12-09 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法
|
|
JP5898520B2
(ja)
|
2011-02-25 |
2016-04-06 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法
|
|
JP6034026B2
(ja)
|
2011-02-25 |
2016-11-30 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法
|
|
JP5829940B2
(ja)
|
2011-02-25 |
2015-12-09 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法
|
|
JP5898521B2
(ja)
|
2011-02-25 |
2016-04-06 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法
|
|
JP6034025B2
(ja)
|
2011-02-25 |
2016-11-30 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法
|
|
JP5947051B2
(ja)
|
2011-02-25 |
2016-07-06 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法
|
|
JP5829941B2
(ja)
|
2011-02-25 |
2015-12-09 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法
|
|
JP5947053B2
(ja)
|
2011-02-25 |
2016-07-06 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法
|
|
DK2688883T3
(en)
|
2011-03-24 |
2016-09-05 |
Noviga Res Ab |
pyrimidine
|
|
WO2012135641A2
(en)
|
2011-03-30 |
2012-10-04 |
H. Lee Moffitt Cancer Center And Research Institute |
Aurora kinase inhibitors and methods of making and using thereof
|
|
US9834518B2
(en)
|
2011-05-04 |
2017-12-05 |
Ariad Pharmaceuticals, Inc. |
Compounds for inhibiting cell proliferation in EGFR-driven cancers
|
|
EP2707357B1
(en)
|
2011-05-10 |
2017-01-18 |
Merck Sharp & Dohme Corp. |
Pyridyl aminopyridines as syk inhibitors
|
|
MX2013013090A
(es)
|
2011-05-10 |
2013-12-16 |
Merck Sharp & Dohme |
Aminopirimidinas como inhibidores de tirosina cinaza del bazo.
|
|
US9145391B2
(en)
|
2011-05-10 |
2015-09-29 |
Merck Sharp & Dohme Corp. |
Bipyridylaminopyridines as Syk inhibitors
|
|
JP6013799B2
(ja)
|
2011-07-19 |
2016-10-25 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法
|
|
JP5886696B2
(ja)
|
2011-07-19 |
2016-03-16 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法
|
|
JP6013797B2
(ja)
|
2011-07-19 |
2016-10-25 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法
|
|
JP6189020B2
(ja)
|
2011-07-19 |
2017-08-30 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法
|
|
JP5912912B2
(ja)
|
2011-07-19 |
2016-04-27 |
住友化学株式会社 |
レジスト組成物及びレジストパターンの製造方法
|
|
PT2736487T
(pt)
|
2011-07-28 |
2019-02-13 |
Rigel Pharmaceuticals Inc |
Novas formulações de (trimetoxifenilamino) pirimidinilo
|
|
MX2014002208A
(es)
|
2011-08-25 |
2014-05-28 |
Hoffmann La Roche |
Inhibidores de serina/treonina quinasa.
|
|
EP2763976B1
(en)
|
2011-10-05 |
2016-05-18 |
Merck Sharp & Dohme Corp. |
2-pyridyl carboxamide-containing spleen tyrosine kinase (syk) inhibitors
|
|
WO2013052391A1
(en)
|
2011-10-05 |
2013-04-11 |
Merck Sharp & Dohme Corp. |
PHENYL CARBOXAMIDE-CONTAINING SPLEEN TYROSINE KINASE (Syk) INHIBITORS
|
|
WO2013052393A1
(en)
|
2011-10-05 |
2013-04-11 |
Merck Sharp & Dohme Corp. |
3-PYRIDYL CARBOXAMIDE-CONTAINING SPLEEN TYROSINE KINASE (Syk) INHIBITORS
|
|
AR088570A1
(es)
|
2011-10-28 |
2014-06-18 |
Celgene Avilomics Res Inc |
Metodos para tratar una enfermedad o trastorno relacionado con la tirosina quinasa de bruton
|
|
BR112014015549A8
(pt)
|
2011-12-22 |
2017-07-04 |
Hoffmann La Roche |
composto, método de inibição da atividade pak1, método para o tratamento, processo, composição, utilização de um composto e invenção
|
|
KR102081042B1
(ko)
|
2012-03-15 |
2020-02-26 |
셀젠 카르 엘엘씨 |
상피 성장 인자 수용체 키나제 억제제의 고체 형태
|
|
PL2825042T3
(pl)
|
2012-03-15 |
2019-02-28 |
Celgene Car Llc |
Sole inhibitora kinazy receptora czynnika wzrostu naskórka
|
|
US20150166591A1
(en)
|
2012-05-05 |
2015-06-18 |
Ariad Pharmaceuticals, Inc. |
Methods and compositions for raf kinase mediated diseases
|
|
EP2863914B1
(en)
|
2012-06-20 |
2018-10-03 |
Merck Sharp & Dohme Corp. |
Pyrazolyl derivatives as syk inhibitors
|
|
US9487504B2
(en)
|
2012-06-20 |
2016-11-08 |
Merck Sharp & Dohme Corp. |
Imidazolyl analogs as syk inhibitors
|
|
EP2863915B1
(en)
|
2012-06-22 |
2017-12-06 |
Merck Sharp & Dohme Corp. |
SUBSTITUTED DIAZINE AND TRIAZINE SPLEEN TYROSINE KINASE (Syk) INHIBITORS
|
|
EP2863916B1
(en)
|
2012-06-22 |
2018-07-18 |
Merck Sharp & Dohme Corp. |
Substituted pyridine spleen tyrosine kinase (syk) inhibitors
|
|
KR101446742B1
(ko)
*
|
2012-08-10 |
2014-10-01 |
한국화학연구원 |
N2,n4-비스(4-(피페라진-1-일)페닐)피리미딘-2,4-디아민 유도체 또는 이의 약학적으로 허용가능한 염 및 이를 유효성분으로 함유하는 암의 예방 또는 치료용 약학적 조성물
|
|
EP2884982B1
(en)
|
2012-08-20 |
2017-09-20 |
Merck Sharp & Dohme Corp. |
SUBSTITUTED PHENYL SPLEEN TYROSINE KINASE (Syk) INHIBITORS
|
|
EP2900665B1
(en)
|
2012-09-28 |
2018-01-03 |
Merck Sharp & Dohme Corp. |
Triazolyl derivatives as syk inhibitors
|
|
WO2014093191A1
(en)
|
2012-12-12 |
2014-06-19 |
Merck Sharp & Dohme Corp. |
AMINO-PYRIMIDINE-CONTAINING SPLEEN TYROSINE KINASE (Syk) INHIBITORS
|
|
EP2934525B1
(en)
|
2012-12-21 |
2019-05-08 |
Merck Sharp & Dohme Corp. |
Thiazole-substituted aminopyridines as spleen tyrosine kinase inhibitors
|
|
US9126950B2
(en)
|
2012-12-21 |
2015-09-08 |
Celgene Avilomics Research, Inc. |
Heteroaryl compounds and uses thereof
|
|
AU2014214846A1
(en)
|
2013-02-08 |
2015-07-23 |
Celgene Avilomics Research, Inc. |
ERK inhibitors and uses thereof
|
|
US9611283B1
(en)
|
2013-04-10 |
2017-04-04 |
Ariad Pharmaceuticals, Inc. |
Methods for inhibiting cell proliferation in ALK-driven cancers
|
|
EP2988749B1
(en)
|
2013-04-26 |
2019-08-14 |
Merck Sharp & Dohme Corp. |
Thiazole-substituted aminopyrimidines as spleen tyrosine kinase inhibitors
|
|
EP2988744A4
(en)
|
2013-04-26 |
2016-11-02 |
Merck Sharp & Dohme |
THIAZOLSUBSTITUTED AMINOHETEROARYLE AS MILZTYROSINKINASE INHIBITOR
|
|
US9492471B2
(en)
|
2013-08-27 |
2016-11-15 |
Celgene Avilomics Research, Inc. |
Methods of treating a disease or disorder associated with Bruton'S Tyrosine Kinase
|
|
EP3076963A4
(en)
|
2013-12-06 |
2017-09-13 |
Millennium Pharmaceuticals, Inc. |
Combination of aurora kinase inhibitors and anti-cd30 antibodies
|
|
US9783531B2
(en)
|
2013-12-20 |
2017-10-10 |
Merck Sharp & Dohme Corp. |
Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
|
|
EP3083560B1
(en)
|
2013-12-20 |
2021-10-27 |
Merck Sharp & Dohme Corp. |
Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
|
|
US9415049B2
(en)
|
2013-12-20 |
2016-08-16 |
Celgene Avilomics Research, Inc. |
Heteroaryl compounds and uses thereof
|
|
US9822107B2
(en)
|
2013-12-20 |
2017-11-21 |
Merck Sharp & Dohme Corp. |
Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
|
|
WO2015138273A1
(en)
|
2014-03-13 |
2015-09-17 |
Merck Sharp & Dohme Corp. |
2-pyrazine carboxamides as spleen tyrosine kinase inhibitors
|
|
CN105017159B
(zh)
*
|
2014-04-28 |
2019-05-17 |
四川大学 |
5-氟-2,4-二取代氨基嘧啶衍生物及其制备方法和用途
|
|
US10106507B2
(en)
|
2014-08-03 |
2018-10-23 |
H. Lee Moffitt Cancer Center and Research Insitute, Inc. |
Potent dual BRD4-kinase inhibitors as cancer therapeutics
|
|
US10005760B2
(en)
|
2014-08-13 |
2018-06-26 |
Celgene Car Llc |
Forms and compositions of an ERK inhibitor
|
|
WO2016029002A2
(en)
*
|
2014-08-22 |
2016-02-25 |
Clovis Oncology, Inc. |
Growth factor receptor inhibitors
|
|
JP2018524292A
(ja)
|
2015-07-21 |
2018-08-30 |
ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. |
オーロラキナーゼインヒビターと化学療法剤の投与
|
|
US10738016B2
(en)
|
2015-10-13 |
2020-08-11 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
BRD4-kinase inhibitors as cancer therapeutics
|
|
WO2017156527A1
(en)
|
2016-03-11 |
2017-09-14 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Aurora kinase and janus kinase inhibitors for prevention of graft versus host disease
|
|
ES2955132T3
(es)
*
|
2016-12-19 |
2023-11-28 |
Epizyme Inc |
Compuestos heterocíclicos sustituidos con amina como inhibidores de EHMT2 y métodos de uso de los mismos
|
|
RU2019128534A
(ru)
*
|
2017-02-15 |
2021-03-16 |
Наньян Текнолоджикал Юниверсити |
Химические соединения для лечения туберкулеза
|
|
CN110621316B
(zh)
|
2017-04-21 |
2024-01-26 |
Epizyme股份有限公司 |
用ehmt2抑制剂进行的组合疗法
|
|
US10683297B2
(en)
*
|
2017-11-19 |
2020-06-16 |
Calitor Sciences, Llc |
Substituted heteroaryl compounds and methods of use
|
|
US11874276B2
(en)
|
2018-04-05 |
2024-01-16 |
Dana-Farber Cancer Institute, Inc. |
STING levels as a biomarker for cancer immunotherapy
|
|
MX2021013662A
(es)
|
2019-05-10 |
2022-03-11 |
Deciphera Pharmaceuticals Llc |
Inhibidores de la autofagia de heteroarilaminopirimidina amida y metodos de uso de estos.
|
|
EP3966207B1
(en)
|
2019-05-10 |
2023-11-01 |
Deciphera Pharmaceuticals, LLC |
Phenylaminopyrimidine amide autophagy inhibitors and methods of use thereof
|
|
IL325201A
(en)
|
2019-06-17 |
2026-02-01 |
Deciphera Pharmaceuticals Llc |
Aminopyrimidine amide autophagy inhibitors and methods of using them
|
|
JP2022539208A
(ja)
|
2019-07-03 |
2022-09-07 |
スミトモ ファーマ オンコロジー, インコーポレイテッド |
チロシンキナーゼ非受容体1(tnk1)阻害剤およびその使用
|
|
US20220305048A1
(en)
|
2019-08-26 |
2022-09-29 |
Dana-Farber Cancer Institute, Inc. |
Use of heparin to promote type 1 interferon signaling
|
|
WO2023107705A1
(en)
|
2021-12-10 |
2023-06-15 |
Incyte Corporation |
Bicyclic amines as cdk12 inhibitors
|
|
CN115232076A
(zh)
*
|
2022-07-25 |
2022-10-25 |
南通大学 |
苯氨基取代的嘧啶氨基酸衍生物及其制备方法与应用
|
|
CN115304551A
(zh)
*
|
2022-07-25 |
2022-11-08 |
南通大学 |
2-((4-吗啉苯基)氨基)嘧啶氨基酸衍生物及其制备方法与应用
|
|
CN115304550A
(zh)
*
|
2022-07-25 |
2022-11-08 |
南通大学 |
哌嗪苯基氨基取代的嘧啶氨基酸衍生物及制备方法与应用
|
|
CN115141150B
(zh)
*
|
2022-07-25 |
2024-04-26 |
南通大学 |
2,4,5-三取代嘧啶羟胺酰衍生物及其制备方法与应用
|
|
CN119431398A
(zh)
*
|
2023-07-31 |
2025-02-14 |
中国科学院上海有机化学研究所 |
R406及其衍生物协同trail的抗肿瘤应用
|