JP2007175057A5 - - Google Patents

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Publication number
JP2007175057A5
JP2007175057A5 JP2007026119A JP2007026119A JP2007175057A5 JP 2007175057 A5 JP2007175057 A5 JP 2007175057A5 JP 2007026119 A JP2007026119 A JP 2007026119A JP 2007026119 A JP2007026119 A JP 2007026119A JP 2007175057 A5 JP2007175057 A5 JP 2007175057A5
Authority
JP
Japan
Prior art keywords
galactosyltransferase
porcine
disrupted
seq
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007026119A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007175057A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2007175057A publication Critical patent/JP2007175057A/ja
Publication of JP2007175057A5 publication Critical patent/JP2007175057A5/ja
Pending legal-status Critical Current

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JP2007026119A 1994-04-13 2007-01-10 α(1,3)ガラクトシルトランスフェラーゼ陰性ブタ Pending JP2007175057A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22893394A 1994-04-13 1994-04-13

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP7526984A Division JPH10504442A (ja) 1994-04-13 1995-03-31 α(1,3)ガラクトシルトランスフェラーゼ陰性ブタ

Publications (2)

Publication Number Publication Date
JP2007175057A JP2007175057A (ja) 2007-07-12
JP2007175057A5 true JP2007175057A5 (enExample) 2007-08-23

Family

ID=22859145

Family Applications (2)

Application Number Title Priority Date Filing Date
JP7526984A Pending JPH10504442A (ja) 1994-04-13 1995-03-31 α(1,3)ガラクトシルトランスフェラーゼ陰性ブタ
JP2007026119A Pending JP2007175057A (ja) 1994-04-13 2007-01-10 α(1,3)ガラクトシルトランスフェラーゼ陰性ブタ

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP7526984A Pending JPH10504442A (ja) 1994-04-13 1995-03-31 α(1,3)ガラクトシルトランスフェラーゼ陰性ブタ

Country Status (9)

Country Link
US (3) US6153428A (enExample)
EP (1) EP0755402B1 (enExample)
JP (2) JPH10504442A (enExample)
AT (1) ATE395418T1 (enExample)
AU (1) AU2233295A (enExample)
CA (1) CA2187802A1 (enExample)
DE (1) DE69535752D1 (enExample)
IL (1) IL113238A0 (enExample)
WO (1) WO1995028412A1 (enExample)

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US7414170B2 (en) * 1999-11-19 2008-08-19 Kirin Beer Kabushiki Kaisha Transgenic bovines capable of human antibody production
US7074983B2 (en) * 1999-11-19 2006-07-11 Kirin Beer Kabushiki Kaisha Transgenic bovine comprising human immunoglobulin loci and producing human immunoglobulin
US7820878B2 (en) 1999-11-19 2010-10-26 Kyowa Hakko Kirin Co., Ltd. Production of ungulates, preferably bovines that produce human immunoglobulins
AU2002232858B2 (en) 2000-12-22 2007-01-11 Sab, Llc Methods for cloning mammals using reprogrammed donor chromatin or donor cells
US7491534B2 (en) 2000-12-22 2009-02-17 Kirin Holdings Kabushiki Kaisha Methods for altering cell fate to generate T-cells specific for an antigen of interest
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US20030101469A1 (en) * 2001-07-09 2003-05-29 Kenneth Bondioli Cloned non-human mammals from contact inhibited donor cells
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PT1534819E (pt) * 2002-08-21 2010-03-11 Revivicor Inc Animais porcinos carecendo de qualquer expressão de alfa 1,3-galactosiltransferase funcional
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WO2005117576A2 (en) * 2004-05-28 2005-12-15 University Of Pittsburgh Of The Commonwealth System Of Higher Education Modification of sugar metabolic process in transgenic cells, tissues and animals
US20060148080A1 (en) * 2004-12-30 2006-07-06 Paul Diamond Methods for supporting and producing human cells and tissues in non-human mammal hosts
US20060147429A1 (en) * 2004-12-30 2006-07-06 Paul Diamond Facilitated cellular reconstitution of organs and tissues
US8187621B2 (en) 2005-04-19 2012-05-29 Advanced Cardiovascular Systems, Inc. Methods and compositions for treating post-myocardial infarction damage
US8828433B2 (en) 2005-04-19 2014-09-09 Advanced Cardiovascular Systems, Inc. Hydrogel bioscaffoldings and biomedical device coatings
US20080125745A1 (en) 2005-04-19 2008-05-29 Shubhayu Basu Methods and compositions for treating post-cardial infarction damage
US8303972B2 (en) 2005-04-19 2012-11-06 Advanced Cardiovascular Systems, Inc. Hydrogel bioscaffoldings and biomedical device coatings
US9539410B2 (en) 2005-04-19 2017-01-10 Abbott Cardiovascular Systems Inc. Methods and compositions for treating post-cardial infarction damage
US7732190B2 (en) 2006-07-31 2010-06-08 Advanced Cardiovascular Systems, Inc. Modified two-component gelation systems, methods of use and methods of manufacture
US9242005B1 (en) 2006-08-21 2016-01-26 Abbott Cardiovascular Systems Inc. Pro-healing agent formulation compositions, methods and treatments
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US8741326B2 (en) 2006-11-17 2014-06-03 Abbott Cardiovascular Systems Inc. Modified two-component gelation systems, methods of use and methods of manufacture
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WO2009069986A2 (en) 2007-11-30 2009-06-04 Korea Research Institute Of Bioscience And Biotechnology Genetically-modified cell line for producing cloned miniature pigs for xenotransplantation and method for preparing the same.
KR101178946B1 (ko) 2008-02-01 2012-09-03 한국생명공학연구원 알파 1,3-갈락토실트랜스퍼라아제 유전자 타겟팅 벡터
KR101068479B1 (ko) 2008-07-30 2011-09-29 한국생명공학연구원 알파 1,3-갈락토실트랜스퍼라아제 유전자 타겟팅 벡터 및그의 용도
CN103891675B (zh) 2009-08-14 2016-12-07 雷维维科公司 用于糖尿病治疗的多转基因猪
CN103492576A (zh) 2011-02-14 2014-01-01 雷维维科公司 用于血管化异种移植物及其衍生物的异种移植的遗传修饰的猪
US9883939B2 (en) 2012-05-08 2018-02-06 The General Hospital Corporation Reducing immunogenicity of xenogeneic transplant tissues
WO2013188358A1 (en) 2012-06-12 2013-12-19 The General Hospital Corporation Miniature swine transgenic for one or more coagulation factors
AU2014341866B2 (en) 2013-11-04 2018-07-05 Lifecell Corporation Methods of removing alpha-galactose
US12058986B2 (en) 2017-04-20 2024-08-13 Egenesis, Inc. Method for generating a genetically modified pig with inactivated porcine endogenous retrovirus (PERV) elements
US10883084B2 (en) 2018-10-05 2021-01-05 Xenotherapeutics, Inc. Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same
MX2021003866A (es) 2018-10-05 2021-09-08 Xenotherapeutics Inc Productos y metodos de xenotransplante.
IL302983A (en) 2020-11-20 2023-07-01 Revivicor Inc Multitransgenic pigs with growth hormone receptor silencing for xenotransplantation

Family Cites Families (2)

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WO1994021799A1 (en) * 1993-03-16 1994-09-29 Austin Research Institute USE OF PORCINE GAL α(1,3) GALACTOSYL TRANSFERASE IN XENOGRAFT THERAPIES
US5849991A (en) * 1994-01-27 1998-12-15 Bresatch Limited Mice homozygous for an inactivated α 1,3-galactosyl transferase gene

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