|
US6331658B1
(en)
*
|
1993-04-20 |
2001-12-18 |
Integris Baptist Medical Center, Inc. |
Genetically engineered mammals for use as organ donors
|
|
US5849991A
(en)
*
|
1994-01-27 |
1998-12-15 |
Bresatch Limited |
Mice homozygous for an inactivated α 1,3-galactosyl transferase gene
|
|
WO1996006165A1
(en)
*
|
1994-08-19 |
1996-02-29 |
The General Hospital Corporation |
Genetically engineered swine cells
|
|
US5913900A
(en)
*
|
1995-06-07 |
1999-06-22 |
Corsscart, Inc. |
Substantially native meniscal cartilage heterografts
|
|
US6231608B1
(en)
|
1995-06-07 |
2001-05-15 |
Crosscart, Inc. |
Aldehyde and glycosidase-treated soft and bone tissue xenografts
|
|
US5865849A
(en)
*
|
1995-06-07 |
1999-02-02 |
Crosscart, Inc. |
Meniscal heterografts
|
|
US5984858A
(en)
*
|
1995-06-07 |
1999-11-16 |
Crosscart, Inc. |
Meniscal xenografts
|
|
US6046379A
(en)
*
|
1995-06-07 |
2000-04-04 |
Stone; Kevin R. |
Meniscal xenografts
|
|
US5782915A
(en)
*
|
1995-09-15 |
1998-07-21 |
Stone; Kevin R. |
Articular cartilage heterografts
|
|
US6110206A
(en)
*
|
1995-09-15 |
2000-08-29 |
Crosscart, Inc. |
Anterior cruciate ligament xenografts
|
|
US5902338A
(en)
*
|
1995-09-15 |
1999-05-11 |
Crosscart, Inc. |
Anterior cruciate ligament heterograft
|
|
US6049025A
(en)
*
|
1995-09-15 |
2000-04-11 |
Stone; Kevin R. |
Articular cartilage xenografts
|
|
US6210440B1
(en)
|
1995-09-15 |
2001-04-03 |
Kevin R. Stone |
Anterior cruciate ligament xenografts
|
|
US5944755A
(en)
*
|
1995-09-15 |
1999-08-31 |
Crosscart, Inc. |
Articular cartilage xenografts
|
|
US6166288A
(en)
*
|
1995-09-27 |
2000-12-26 |
Nextran Inc. |
Method of producing transgenic animals for xenotransplantation expressing both an enzyme masking or reducing the level of the gal epitope and a complement inhibitor
|
|
WO1997016064A1
(en)
*
|
1995-11-03 |
1997-05-09 |
The Mount Sinai Medical Center |
Methods and compositions for the reduction of xenotransplantation rejection
|
|
US6235969B1
(en)
*
|
1997-01-10 |
2001-05-22 |
University Of Massachusetts |
Cloning pigs using donor nuclei from non-quiescent differentiated cells
|
|
US6011197A
(en)
|
1997-03-06 |
2000-01-04 |
Infigen, Inc. |
Method of cloning bovines using reprogrammed non-embryonic bovine cells
|
|
CA2349562A1
(en)
|
1998-03-06 |
1999-09-10 |
Crosscart, Inc. |
Soft tissue xenografts
|
|
US6972041B1
(en)
|
1998-03-16 |
2005-12-06 |
Crosscart, Inc. |
Bone xenografts
|
|
US6383732B1
(en)
|
1999-02-11 |
2002-05-07 |
Crosscart, Inc. |
Method of preparing xenograft heart valves
|
|
US6509187B2
(en)
*
|
1998-05-25 |
2003-01-21 |
Agrobiogen Gmbh |
Method and device for collection and preparation of tissue samples for molecular genetic diagnostics
|
|
JP2990268B1
(ja)
*
|
1998-08-31 |
1999-12-13 |
工業技術院長 |
機能性核酸転写用発現系
|
|
AU6193699A
(en)
*
|
1998-09-25 |
2000-04-17 |
Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts |
Antisense-sequences for inhibiting the expression of the adhesion molecule icam-1
|
|
WO2000022098A1
(en)
|
1998-10-12 |
2000-04-20 |
Geron Bio-Med Limited |
Porcine oocytes with improved developmental competence
|
|
AU6522599A
(en)
*
|
1998-10-23 |
2000-05-15 |
Children's Medical Center Corporation |
Use of a self-cleaving rna motif to modulate gene expression
|
|
US6258998B1
(en)
|
1998-11-24 |
2001-07-10 |
Infigen, Inc. |
Method of cloning porcine animals
|
|
US6700037B2
(en)
*
|
1998-11-24 |
2004-03-02 |
Infigen, Inc. |
Method of cloning porcine animals
|
|
US6267786B1
(en)
|
1999-02-11 |
2001-07-31 |
Crosscart, Inc. |
Proteoglycan-reduced soft tissue xenografts
|
|
US20020012660A1
(en)
*
|
1999-03-04 |
2002-01-31 |
Alan Colman |
Method of preparing a somatic cells for nuclear transfer
|
|
EP1220928A2
(en)
*
|
1999-09-30 |
2002-07-10 |
Alexion Pharmaceuticals, Inc. |
Compositions and methods for altering gene expression
|
|
CA2426669A1
(en)
*
|
1999-10-22 |
2001-05-03 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
.alpha.1-3 galactosyltransferase gene and promoter
|
|
US7253334B2
(en)
|
2000-12-22 |
2007-08-07 |
Aurox, Llc |
Methods for cloning non-human mammals using reprogrammed donor chromatin or donor cells
|
|
AU1777301A
(en)
*
|
1999-11-19 |
2001-05-30 |
Hematech, Llc |
Production of ungulates, preferably bovines that produce human immunoglobulins
|
|
US7414170B2
(en)
*
|
1999-11-19 |
2008-08-19 |
Kirin Beer Kabushiki Kaisha |
Transgenic bovines capable of human antibody production
|
|
US7074983B2
(en)
*
|
1999-11-19 |
2006-07-11 |
Kirin Beer Kabushiki Kaisha |
Transgenic bovine comprising human immunoglobulin loci and producing human immunoglobulin
|
|
US7820878B2
(en)
|
1999-11-19 |
2010-10-26 |
Kyowa Hakko Kirin Co., Ltd. |
Production of ungulates, preferably bovines that produce human immunoglobulins
|
|
US20020142397A1
(en)
*
|
2000-12-22 |
2002-10-03 |
Philippe Collas |
Methods for altering cell fate
|
|
US7491534B2
(en)
|
2000-12-22 |
2009-02-17 |
Kirin Holdings Kabushiki Kaisha |
Methods for altering cell fate to generate T-cells specific for an antigen of interest
|
|
US7126039B2
(en)
|
2001-03-21 |
2006-10-24 |
Geron Corporation |
Animal tissue with carbohydrate antigens compatible for human transplantation
|
|
AU2002242538B2
(en)
*
|
2001-03-21 |
2007-06-28 |
Geron Corporation |
Animal tissue with carbohydrate antigens compatible for human transplantation
|
|
US20030092174A1
(en)
*
|
2001-05-14 |
2003-05-15 |
Monika Liljedahl |
Tissues or organs for use in xenotransplantation
|
|
US20030153044A1
(en)
*
|
2001-05-14 |
2003-08-14 |
Monika Liljedahl |
Tissues or organs for use in xenotransplantation
|
|
US6702744B2
(en)
|
2001-06-20 |
2004-03-09 |
Advanced Cardiovascular Systems, Inc. |
Agents that stimulate therapeutic angiogenesis and techniques and devices that enable their delivery
|
|
AU2002326353A1
(en)
*
|
2001-07-09 |
2003-01-29 |
Alexion Pharmaceuticals Inc. |
Cloned non-human mammals from contact inhibited donor cells
|
|
US8608661B1
(en)
|
2001-11-30 |
2013-12-17 |
Advanced Cardiovascular Systems, Inc. |
Method for intravascular delivery of a treatment agent beyond a blood vessel wall
|
|
CA2471035C
(en)
*
|
2001-12-21 |
2014-05-13 |
The Curators Of The University Of Missouri |
Knockout swine and methods for making the same
|
|
JP2003225089A
(ja)
*
|
2002-02-04 |
2003-08-12 |
National Institute Of Agrobiological Sciences |
ブタｒａｇ−１遺伝子およびその利用
|
|
US7361368B2
(en)
|
2002-06-28 |
2008-04-22 |
Advanced Cardiovascular Systems, Inc. |
Device and method for combining a treatment agent and a gel
|
|
JP2005535343A
(ja)
|
2002-08-14 |
2005-11-24 |
イマージ バイオセラピューティクス，インコーポレーテッド |
α（１，３）−ガラクトシルトランスフェラーゼ欠損細胞、選択する方法、およびそれらから作製されたα（１，３）−ガラクトシルトランスフェラーゼ欠損ブタ
|
|
ES2338111T3
(es)
|
2002-08-21 |
2010-05-04 |
Revivicor, Inc. |
Animales porcinos que carecen de cualquier expresion de alfa 1,3 galactosiltransferasa funcional.
|
|
JP2006505291A
(ja)
*
|
2002-11-08 |
2006-02-16 |
ヘマテック，エルエルシー |
プリオンタンパク質活性が低減されたトランスジェニック有蹄動物及びその用途
|
|
US8383158B2
(en)
|
2003-04-15 |
2013-02-26 |
Abbott Cardiovascular Systems Inc. |
Methods and compositions to treat myocardial conditions
|
|
US8038991B1
(en)
|
2003-04-15 |
2011-10-18 |
Abbott Cardiovascular Systems Inc. |
High-viscosity hyaluronic acid compositions to treat myocardial conditions
|
|
US8821473B2
(en)
|
2003-04-15 |
2014-09-02 |
Abbott Cardiovascular Systems Inc. |
Methods and compositions to treat myocardial conditions
|
|
CA2533259C
(en)
*
|
2003-07-21 |
2014-01-28 |
Lifecell Corporation |
Acellular tissue matrices made from galactose .alpha.-1,3-galactose-deficient tissue
|
|
US7560538B2
(en)
|
2003-11-05 |
2009-07-14 |
University Of Pittsburgh |
Porcine isogloboside 3 synthase protein, cDNA, genomic organization, and regulatory region
|
|
DK1734814T3
(en)
|
2004-03-17 |
2015-04-07 |
Revivicor Inc |
Tissue DERIVED FROM ANIMALS IS MISSING ANY EXPRESSION OF FUNCTIONAL ALPHA-1,3 galactosyltransferase
|
|
CA2563064A1
(en)
|
2004-04-22 |
2005-11-10 |
Kirin Beer Kabushiki Kaisha |
Transgenic animals and uses thereof
|
|
WO2005117576A2
(en)
*
|
2004-05-28 |
2005-12-15 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Modification of sugar metabolic process in transgenic cells, tissues and animals
|
|
US20060148080A1
(en)
*
|
2004-12-30 |
2006-07-06 |
Paul Diamond |
Methods for supporting and producing human cells and tissues in non-human mammal hosts
|
|
US20060147429A1
(en)
*
|
2004-12-30 |
2006-07-06 |
Paul Diamond |
Facilitated cellular reconstitution of organs and tissues
|
|
US9539410B2
(en)
|
2005-04-19 |
2017-01-10 |
Abbott Cardiovascular Systems Inc. |
Methods and compositions for treating post-cardial infarction damage
|
|
US8187621B2
(en)
|
2005-04-19 |
2012-05-29 |
Advanced Cardiovascular Systems, Inc. |
Methods and compositions for treating post-myocardial infarction damage
|
|
US20080125745A1
(en)
|
2005-04-19 |
2008-05-29 |
Shubhayu Basu |
Methods and compositions for treating post-cardial infarction damage
|
|
US8303972B2
(en)
|
2005-04-19 |
2012-11-06 |
Advanced Cardiovascular Systems, Inc. |
Hydrogel bioscaffoldings and biomedical device coatings
|
|
US8828433B2
(en)
|
2005-04-19 |
2014-09-09 |
Advanced Cardiovascular Systems, Inc. |
Hydrogel bioscaffoldings and biomedical device coatings
|
|
US7732190B2
(en)
|
2006-07-31 |
2010-06-08 |
Advanced Cardiovascular Systems, Inc. |
Modified two-component gelation systems, methods of use and methods of manufacture
|
|
US9242005B1
(en)
|
2006-08-21 |
2016-01-26 |
Abbott Cardiovascular Systems Inc. |
Pro-healing agent formulation compositions, methods and treatments
|
|
US9005672B2
(en)
|
2006-11-17 |
2015-04-14 |
Abbott Cardiovascular Systems Inc. |
Methods of modifying myocardial infarction expansion
|
|
US8741326B2
(en)
|
2006-11-17 |
2014-06-03 |
Abbott Cardiovascular Systems Inc. |
Modified two-component gelation systems, methods of use and methods of manufacture
|
|
US8192760B2
(en)
|
2006-12-04 |
2012-06-05 |
Abbott Cardiovascular Systems Inc. |
Methods and compositions for treating tissue using silk proteins
|
|
WO2009069986A2
(en)
|
2007-11-30 |
2009-06-04 |
Korea Research Institute Of Bioscience And Biotechnology |
Genetically-modified cell line for producing cloned miniature pigs for xenotransplantation and method for preparing the same.
|
|
KR101178946B1
(ko)
|
2008-02-01 |
2012-09-03 |
한국생명공학연구원 |
알파 1,3-갈락토실트랜스퍼라아제 유전자 타겟팅 벡터
|
|
KR101068479B1
(ko)
|
2008-07-30 |
2011-09-29 |
한국생명공학연구원 |
알파 1,3-갈락토실트랜스퍼라아제 유전자 타겟팅 벡터 및그의 용도
|
|
EP2464219B1
(en)
|
2009-08-14 |
2019-10-23 |
Revivicor, Inc. |
Multi-transgenic pigs for diabetes treatment
|
|
CA2827348C
(en)
|
2011-02-14 |
2021-02-23 |
Revivicor, Inc. |
Genetically modified pigs for xenotransplantation of vascularized xenografts and derivatives thereof
|
|
US9883939B2
(en)
|
2012-05-08 |
2018-02-06 |
The General Hospital Corporation |
Reducing immunogenicity of xenogeneic transplant tissues
|
|
US9980471B2
(en)
|
2012-06-12 |
2018-05-29 |
The General Hospital Corporation |
Miniature swine transgenic for one or more coagulation factors
|
|
ES2846758T3
(es)
|
2013-11-04 |
2021-07-29 |
Lifecell Corp |
Métodos para eliminar la alfa-galactosa
|
|
EP3612023A4
(en)
|
2017-04-20 |
2021-05-12 |
Egenesis, Inc. |
METHOD FOR PRODUCING GENETICALLY MODIFIED ANIMALS
|
|
KR20210089659A
(ko)
|
2018-10-05 |
2021-07-16 |
제노세라퓨틱스, 인코포레이티드 |
이종이식 생성물 및 방법
|
|
US10883084B2
(en)
|
2018-10-05 |
2021-01-05 |
Xenotherapeutics, Inc. |
Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same
|
|
CN117279502A
(zh)
|
2020-11-20 |
2023-12-22 |
雷维维科公司 |
用于异种移植的生长激素受体敲除的多转基因猪
|