JP2006528618A5 - - Google Patents
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- Publication number
- JP2006528618A5 JP2006528618A5 JP2006520907A JP2006520907A JP2006528618A5 JP 2006528618 A5 JP2006528618 A5 JP 2006528618A5 JP 2006520907 A JP2006520907 A JP 2006520907A JP 2006520907 A JP2006520907 A JP 2006520907A JP 2006528618 A5 JP2006528618 A5 JP 2006528618A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- cancer
- parp
- nucleic acid
- defective
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0317466.1A GB0317466D0 (en) | 2003-07-25 | 2003-07-25 | Use |
| GB0317466.1 | 2003-07-25 | ||
| PCT/GB2004/003235 WO2005012524A1 (en) | 2003-07-25 | 2004-07-23 | Use of rnai inhibiting parp activtiy for the manufacture of a medicament for the treatment of cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011246988A Division JP5547164B2 (ja) | 2003-07-25 | 2011-11-11 | 癌を治療するための医薬の製造におけるPARP活性阻害性RNAiの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006528618A JP2006528618A (ja) | 2006-12-21 |
| JP2006528618A5 true JP2006528618A5 (enExample) | 2007-08-02 |
| JP5519097B2 JP5519097B2 (ja) | 2014-06-11 |
Family
ID=27772701
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006520907A Expired - Lifetime JP5519097B2 (ja) | 2003-07-25 | 2004-07-23 | 癌を治療するための医薬の製造におけるPARP活性阻害性RNAiの使用 |
| JP2011246988A Expired - Lifetime JP5547164B2 (ja) | 2003-07-25 | 2011-11-11 | 癌を治療するための医薬の製造におけるPARP活性阻害性RNAiの使用 |
| JP2013147532A Expired - Lifetime JP5848728B2 (ja) | 2003-07-25 | 2013-07-16 | 癌を治療するための医薬の製造におけるPARP活性阻害性RNAiの使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011246988A Expired - Lifetime JP5547164B2 (ja) | 2003-07-25 | 2011-11-11 | 癌を治療するための医薬の製造におけるPARP活性阻害性RNAiの使用 |
| JP2013147532A Expired - Lifetime JP5848728B2 (ja) | 2003-07-25 | 2013-07-16 | 癌を治療するための医薬の製造におけるPARP活性阻害性RNAiの使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (5) | US8859562B2 (enExample) |
| EP (1) | EP1649017B2 (enExample) |
| JP (3) | JP5519097B2 (enExample) |
| KR (1) | KR101136702B1 (enExample) |
| CN (3) | CN1856572B (enExample) |
| AT (1) | ATE516353T1 (enExample) |
| AU (1) | AU2004261779B2 (enExample) |
| BR (1) | BRPI0412909B1 (enExample) |
| CA (1) | CA2533423C (enExample) |
| DK (1) | DK1649017T4 (enExample) |
| ES (1) | ES2367433T5 (enExample) |
| GB (2) | GB0317466D0 (enExample) |
| NO (1) | NO338398B1 (enExample) |
| NZ (1) | NZ545307A (enExample) |
| PL (1) | PL1649017T5 (enExample) |
| PT (1) | PT1649017E (enExample) |
| WO (1) | WO2005012524A1 (enExample) |
| ZA (1) | ZA200601386B (enExample) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6956035B2 (en) | 2001-08-31 | 2005-10-18 | Inotek Pharmaceuticals Corporation | Isoquinoline derivatives and methods of use thereof |
| CN100398519C (zh) | 2003-02-28 | 2008-07-02 | 伊诺泰克制药公司 | 四环苯甲酰胺衍生物及其用法 |
| GB0317466D0 (en) * | 2003-07-25 | 2003-08-27 | Univ Sheffield | Use |
| MXPA06000993A (es) | 2003-07-25 | 2006-08-31 | Cancer Rec Tech Ltd | Inhbidores triciclicos de parp. |
| SG150548A1 (en) * | 2003-12-01 | 2009-03-30 | Kudos Pharm Ltd | Dna damage repair inhibitors for treatment of cancer |
| WO2006078503A2 (en) * | 2005-01-07 | 2006-07-27 | Arqule, Inc. | Compositions for modulation of parp and methods for screening for same |
| CA2595290C (en) | 2005-01-19 | 2013-06-25 | Mgi Gp, Inc. | Diazabenzo[de]anthracen-3-one compounds and methods for inhibiting parp |
| RU2007135362A (ru) | 2005-02-25 | 2009-03-27 | Инотек Фармасьютикалз Корпорейшн (Us) | Тетрациклические амино- и карбоксамидосоединения и способ их применения |
| CN101316592A (zh) | 2005-08-24 | 2008-12-03 | 伊诺泰克制药公司 | 茚并异喹啉酮类似物及其用法 |
| JP2009517403A (ja) * | 2005-11-25 | 2009-04-30 | ユニバーシティー オブ メディシン アンド デンティストリー オブ ニュージャージー | Parp−1阻害剤の使用 |
| JP2010506939A (ja) | 2006-10-20 | 2010-03-04 | ダナ ファーバー キャンサー インスティテュート,インコーポレイテッド | ガンを処置するためのdna損傷修復阻害剤および方法 |
| PT2099442E (pt) * | 2006-12-26 | 2015-02-10 | Pharmacyclics Inc | Métodos de utilização de inibidores de histona desacetilase e monitorização de biomarcadores em terapia de combinação |
| MX2009009183A (es) | 2007-02-28 | 2009-09-07 | Inotek Pharmaceuticals Corp | Analogos de indenoisoquinolinona y metodos de utilizacion de los mismos. |
| GB0707556D0 (en) * | 2007-04-19 | 2007-05-30 | Isis Innovation | Treatment for cancer |
| JP5335673B2 (ja) | 2007-06-20 | 2013-11-06 | 学校法人 埼玉医科大学 | 子宮癌、乳癌、及び膀胱癌の予防乃至治療に好適な二本鎖核酸分子、癌細胞増殖抑制剤、並びに医薬 |
| WO2009027650A1 (en) * | 2007-08-24 | 2009-03-05 | The Institute Of Cancer: Royal Cancer Hospital | Materials and methods for exploiting synthetic lethality in brca-associated cancers |
| SI2209375T1 (sl) | 2007-10-03 | 2014-12-31 | Eisai Inc. | Spojine inhibitorja PARP in metode uporabe |
| WO2009113579A1 (ja) | 2008-03-11 | 2009-09-17 | 学校法人埼玉医科大学 | 癌の予防乃至治療に好適な二本鎖核酸分子、癌細胞増殖抑制剤、並びに医薬 |
| JP2012507010A (ja) * | 2008-10-24 | 2012-03-22 | マグナケム インターナショナル ラボラトリーズ, インコーポレイテッド | Rad9と選択的に相互作用する化合物をスクリーニングするための方法 |
| US8268550B2 (en) * | 2009-06-26 | 2012-09-18 | Massachusetts Institute Of Technology | Compositions and methods for identification of PARP function, inhibitors, and activators |
| WO2010151664A2 (en) | 2009-06-26 | 2010-12-29 | Massachusetts Institute Of Technology | Compositions and methods for treating cancer and modulating stress granule formation |
| US8435961B2 (en) * | 2009-06-26 | 2013-05-07 | Massachusetts Institute Of Technology | Methods and compositions for increasing the activity of inhibitory RNA |
| WO2011058367A2 (en) | 2009-11-13 | 2011-05-19 | Astrazeneca Ab | Diagnostic test for predicting responsiveness to treatment with poly(adp-ribose) polymerase (parp) inhibitor |
| ES2704303T3 (es) | 2010-08-24 | 2019-03-15 | Dana Farber Cancer Inst Inc | Procedimientos para la predicción de una respuesta contra el cáncer |
| SG189280A1 (en) * | 2010-10-07 | 2013-05-31 | Agency Science Tech & Res | Parp-1 inhibitors |
| MX368261B (es) | 2011-07-22 | 2019-09-25 | Pacylex Pharmaceuticals Inc | Letalidad sintetica y el tratamiento de cancer. |
| ES2687024T3 (es) * | 2012-02-23 | 2018-10-23 | Children's Medical Center Corporation | Procedimientos para predecir la respuesta contra el cáncer |
| US9359367B2 (en) | 2012-07-09 | 2016-06-07 | Lupin Limited | Tetrahydroquinazolinone derivatives as PARP inhibitors |
| EP2986709A4 (en) * | 2013-04-16 | 2017-03-15 | University Of Washington Through Its Center For Commercialization | Activating an alternative pathway for homology-directed repair to stimulate targeted gene correction and genome engineering |
| AU2014321200A1 (en) * | 2013-09-23 | 2016-05-05 | The University Of Chicago | Methods and compositions relating to cancer therapy with DNA damaging agents |
| EP3102680B1 (en) | 2014-02-07 | 2018-12-19 | VIB vzw | Inhibition of neat1 for treatment of solid tumors |
| US9889141B2 (en) * | 2014-10-14 | 2018-02-13 | Institute For Cancer Research | Combined inhibition of the vitamin D receptor and poly(ADP) ribose polymerase (PARP) in the treatment of cancer |
| PL3277321T3 (pl) | 2015-04-01 | 2024-11-18 | Anaptysbio, Inc. | Przeciwciała skierowane przeciwko białku 3 immunoglobuliny limfocytów t i mucyny (tim-3) |
| EP3325662B1 (en) | 2015-07-17 | 2023-08-30 | Pacylex Pharmaceuticals Inc. | Epigenetic silencing of nmt2 |
| KR20180059922A (ko) | 2015-10-02 | 2018-06-05 | 유니버시티 오브 코펜하겐 | 히스톤 리더 도메인을 차단하는 소분자 |
| DK3653709T3 (da) | 2016-02-22 | 2021-03-08 | Caribou Biosciences Inc | Fremgangsmåder til modulering af dna-reparationsresultater |
| MA50677A (fr) * | 2016-11-01 | 2021-07-14 | Anaptysbio Inc | Anticorps dirigés contre la protéine d'immunoglobuline de lymphocytes t et mucine 3 (tim-3) |
| AU2018205401B2 (en) | 2017-01-09 | 2025-01-02 | Tesaro, Inc. | Methods of treating cancer with anti-TIM-3 antibodies |
| CN107058233A (zh) * | 2017-05-03 | 2017-08-18 | 上海长海医院 | 一种减小肿瘤细胞对抗肿瘤药物的耐药性的方法 |
| CN108048465A (zh) * | 2017-12-20 | 2018-05-18 | 李风玲 | 一种抑制PARP基因用于治疗乳腺癌的siRNA |
| US10519136B2 (en) | 2017-12-29 | 2019-12-31 | Accutar Biotechnology | Dual inhibitors of PARP1 and CDK |
| AU2019205325A1 (en) | 2018-01-05 | 2020-08-13 | Cybrexa 1, Inc. | Compounds, compositions, and methods for treatment of diseases involving acidic or hypoxic diseased tissues |
| KR20210097124A (ko) | 2018-10-30 | 2021-08-06 | 리페어 세라퓨틱스 인크. | 화합물, 약제 조성물, 및 화합물 제조 방법 및 atr 키나제 억제제로서의 이것들의 사용 방법 |
| PH12021552205A1 (en) * | 2019-03-25 | 2022-06-13 | Cyteir Therapeutics Inc | Combinations of rad51 and parp inhibitors |
| BR112022000297A2 (pt) | 2019-07-10 | 2022-03-15 | Cybrexa 3 Inc | Conjugados de peptídeos de agentes de alvo de microtúbulos como terapêuticos |
| MX2022000449A (es) | 2019-07-10 | 2022-04-25 | Cybrexa 2 Inc | Conjugados peptídicos de citotoxinas como terapéuticos. |
| KR20220035925A (ko) | 2019-07-22 | 2022-03-22 | 리페어 세라퓨틱스 인크. | Atr 키나제 억제제로서의 치환된 2-모르폴리노피리딘 유도체 |
| CN116234803B (zh) | 2019-12-23 | 2026-06-30 | 冰洲石生物科技公司 | 用于治疗癌症的雌激素受体降解剂和细胞周期蛋白依赖性激酶抑制剂的组合 |
| ES3014370T3 (en) | 2020-04-28 | 2025-04-22 | Rhizen Pharmaceuticals Ag | Novel compounds useful as poly(adp-ribose) polymerase (parp) inhibitors |
| WO2022090938A1 (en) | 2020-10-31 | 2022-05-05 | Rhizen Pharmaceuticals Ag | Phthalazinone derivatives useful as parp inhibitors |
| CN114836472A (zh) * | 2021-02-01 | 2022-08-02 | 中国人民解放军军事科学院军事医学研究院 | PARP-1shRNA重组慢病毒载体、该载体稳定转染HaCaT的细胞系及其应用 |
| WO2022215034A1 (en) | 2021-04-08 | 2022-10-13 | Rhizen Pharmaceuticals Ag | Inhibitors of poly(adp-ribose) polymerase |
| AU2022276986B2 (en) | 2021-05-18 | 2025-07-03 | Onconic Therapeutics Inc. | Parp inhibitor-resistant cancer therapeutic agent |
| WO2023089032A1 (en) * | 2021-11-19 | 2023-05-25 | Institut Curie | Methods for the treatment of hrd cancer and brca-associated cancer |
| WO2023201338A1 (en) | 2022-04-15 | 2023-10-19 | Ideaya Biosciences, Inc. | Combination therapy comprising a mat2a inhibitor and a parp inhibitor |
| EP4532493A1 (en) | 2022-06-01 | 2025-04-09 | Ideaya Biosciences, Inc. | Thiadiazolyl derivatives as dna polymerase theta inhibitors and uses thereof |
| WO2024194402A1 (en) * | 2023-03-21 | 2024-09-26 | Institut Curie | Farnesyl transferase inhibitor for use in methods for the treatment of hrd cancer |
| EP4683630A1 (en) * | 2023-03-21 | 2026-01-28 | Institut Curie | Vps4b inhibitor for use in methods for the treatment of hrd cancer |
| KR20260019479A (ko) | 2023-05-04 | 2026-02-10 | 레볼루션 메디슨즈, 인크. | Ras 관련 질환 또는 장애를 위한 병용 요법 |
| CN121889155A (zh) | 2023-08-07 | 2026-04-17 | 锐新医药公司 | 用于治疗ras蛋白相关疾病或病症的rmc-6291 |
| AU2024360465A1 (en) | 2023-10-12 | 2026-04-09 | Revolution Medicines, Inc. | Macrocyclic ras inhibitors |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025183523A1 (ko) * | 2024-02-29 | 2025-09-04 | 아주대학교 산학협력단 | Parp 억제제 감수성 증가 방법 |
| WO2025217307A1 (en) | 2024-04-09 | 2025-10-16 | Revolution Medicines, Inc. | Methods for predicting response to a ras(on) inhibitor and combination therapies |
| WO2025240847A1 (en) | 2024-05-17 | 2025-11-20 | Revolution Medicines, Inc. | Ras inhibitors |
| US20250375445A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026050446A1 (en) | 2024-08-29 | 2026-03-05 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026072904A2 (en) | 2024-09-26 | 2026-04-02 | Revolution Medicines, Inc. | Compositions and methods for treating lung cancer |
| WO2026090116A2 (en) | 2024-10-21 | 2026-04-30 | Revolution Medicines, Inc. | Ras inhibitors |
| US20260108528A1 (en) | 2024-10-22 | 2026-04-23 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2026090245A1 (en) | 2024-10-22 | 2026-04-30 | Revolution Medicines, Inc. | Use of ras inhibitors for treating cancer |
| WO2026106912A1 (en) | 2024-11-12 | 2026-05-21 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026112260A1 (en) | 2024-11-21 | 2026-05-28 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026122764A2 (en) | 2024-12-06 | 2026-06-11 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026128688A2 (en) | 2024-12-13 | 2026-06-18 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026161839A1 (en) | 2025-01-27 | 2026-07-30 | Revolution Medicines, Inc. | Ras inhibitors |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5484951A (en) | 1990-10-19 | 1996-01-16 | Octamer, Incorporated | 5-iodo-6-amino-6-nitroso-1,2-benzopyrones useful as cytostatic and antiviral agents |
| US5098861A (en) | 1991-01-08 | 1992-03-24 | Unitrode Corporation | Method of processing a semiconductor substrate including silicide bonding |
| US5464871A (en) | 1993-05-12 | 1995-11-07 | Octamer, Inc. | Aromatic nitro and nitroso compounds and their metabolites useful as anti-viral and anti-tumor agents |
| EP0600831A1 (de) | 1992-11-27 | 1994-06-08 | Ciba-Geigy Ag | Phthalazinonderivate |
| GB9404485D0 (en) * | 1994-03-09 | 1994-04-20 | Cancer Res Campaign Tech | Benzamide analogues |
| WO1999008680A1 (en) * | 1997-08-15 | 1999-02-25 | The Johns Hopkins University | Method of using selective parp inhibitors to prevent or treat neurotoxicity |
| EP1140936B1 (en) * | 1999-01-11 | 2004-03-17 | Agouron Pharmaceuticals, Inc. | Tricyclic inhibitors of poly(adp-ribose) polymerases |
| US6635677B2 (en) | 1999-08-13 | 2003-10-21 | Case Western Reserve University | Methoxyamine combinations in the treatment of cancer |
| ECSP003637A (es) * | 1999-08-31 | 2002-03-25 | Agouron Pharma | Inhibidores triciclicos de poli (adp-ribosa) polimerasas |
| DE10022925A1 (de) | 2000-05-11 | 2001-11-15 | Basf Ag | Substituierte Indole als PARP-Inhibitoren |
| HRP20030081A2 (en) * | 2000-08-08 | 2005-02-28 | Sanofi-Aventis | Benzimidazole derivatives, preparation and therapeutic use thereof |
| HU228960B1 (hu) | 2000-10-30 | 2013-07-29 | Kudos Pharm Ltd | Ftalazinon-származékok |
| WO2002090334A1 (en) | 2001-05-08 | 2002-11-14 | Kudos Pharmaceuticals Limited | Isoquinolinone derivatives as parp inhibitors |
| US7072771B2 (en) * | 2001-06-07 | 2006-07-04 | University Of Kentucky Research Foundation | Selective PARP-1 targeting for designing chemo/radio sensitizing agents |
| US20030073692A1 (en) | 2001-08-07 | 2003-04-17 | Pharmacia & Upjohn S.P.A. | Amino-phthalazinone derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them |
| AUPS019702A0 (en) | 2002-01-29 | 2002-02-21 | Fujisawa Pharmaceutical Co., Ltd. | Condensed heterocyclic compounds |
| US20030229004A1 (en) | 2002-03-20 | 2003-12-11 | Pangene Corporation | Modulation of tumor cells using BER inhibitors in combination with a sensitizing agent and DSBR inhibitors |
| DE60335359D1 (de) | 2002-04-30 | 2011-01-27 | Kudos Pharm Ltd | Phthalazinonderivate |
| AU2003253906A1 (en) | 2002-07-19 | 2004-02-09 | Osteotech, Inc. | Chisels and procedure for insertion of spinal implant in a spinal disc space |
| PL1633724T3 (pl) * | 2003-03-12 | 2011-10-31 | Kudos Pharm Ltd | Pochodne ftalazynonu |
| US7176188B2 (en) | 2003-05-07 | 2007-02-13 | UniversitéLaval | Method of lethally sensitizing human and animal cells |
| GB0317466D0 (en) * | 2003-07-25 | 2003-08-27 | Univ Sheffield | Use |
| MXPA06000993A (es) * | 2003-07-25 | 2006-08-31 | Cancer Rec Tech Ltd | Inhbidores triciclicos de parp. |
| SG150548A1 (en) | 2003-12-01 | 2009-03-30 | Kudos Pharm Ltd | Dna damage repair inhibitors for treatment of cancer |
-
2003
- 2003-07-25 GB GBGB0317466.1A patent/GB0317466D0/en not_active Ceased
-
2004
- 2004-07-23 CN CN2004800272941A patent/CN1856572B/zh not_active Expired - Lifetime
- 2004-07-23 PL PL04743564T patent/PL1649017T5/pl unknown
- 2004-07-23 CN CN201210332472.8A patent/CN102935230B/zh not_active Expired - Lifetime
- 2004-07-23 AU AU2004261779A patent/AU2004261779B2/en not_active Expired
- 2004-07-23 GB GB0603874A patent/GB2419882B/en not_active Expired - Lifetime
- 2004-07-23 KR KR1020067001650A patent/KR101136702B1/ko not_active Expired - Lifetime
- 2004-07-23 EP EP04743564.9A patent/EP1649017B2/en not_active Expired - Lifetime
- 2004-07-23 CN CN2004800273183A patent/CN1856313B/zh not_active Expired - Lifetime
- 2004-07-23 CA CA2533423A patent/CA2533423C/en not_active Expired - Lifetime
- 2004-07-23 PT PT04743564T patent/PT1649017E/pt unknown
- 2004-07-23 NZ NZ545307A patent/NZ545307A/en not_active IP Right Cessation
- 2004-07-23 BR BRPI0412909-1A patent/BRPI0412909B1/pt not_active IP Right Cessation
- 2004-07-23 US US10/555,507 patent/US8859562B2/en active Active
- 2004-07-23 ES ES04743564.9T patent/ES2367433T5/es not_active Expired - Lifetime
- 2004-07-23 AT AT04743564T patent/ATE516353T1/de active
- 2004-07-23 JP JP2006520907A patent/JP5519097B2/ja not_active Expired - Lifetime
- 2004-07-23 DK DK04743564.9T patent/DK1649017T4/da active
- 2004-07-23 WO PCT/GB2004/003235 patent/WO2005012524A1/en not_active Ceased
-
2006
- 2006-02-16 ZA ZA200601386A patent/ZA200601386B/en unknown
- 2006-02-24 NO NO20060906A patent/NO338398B1/no unknown
-
2011
- 2011-11-11 JP JP2011246988A patent/JP5547164B2/ja not_active Expired - Lifetime
-
2013
- 2013-07-16 JP JP2013147532A patent/JP5848728B2/ja not_active Expired - Lifetime
-
2014
- 2014-07-02 US US14/322,759 patent/US20150005327A1/en not_active Abandoned
-
2017
- 2017-07-14 US US15/650,459 patent/US20180000822A1/en not_active Abandoned
-
2019
- 2019-10-10 US US16/598,808 patent/US20200237762A1/en not_active Abandoned
-
2021
- 2021-11-16 US US17/528,034 patent/US20220062286A1/en not_active Abandoned
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