JP2006528182A5 - - Google Patents
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- Publication number
- JP2006528182A5 JP2006528182A5 JP2006521149A JP2006521149A JP2006528182A5 JP 2006528182 A5 JP2006528182 A5 JP 2006528182A5 JP 2006521149 A JP2006521149 A JP 2006521149A JP 2006521149 A JP2006521149 A JP 2006521149A JP 2006528182 A5 JP2006528182 A5 JP 2006528182A5
- Authority
- JP
- Japan
- Prior art keywords
- less
- segment
- suspension
- minutes
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000725 suspension Substances 0.000 description 28
- 239000008194 pharmaceutical composition Substances 0.000 description 20
- 229940126409 proton pump inhibitor Drugs 0.000 description 17
- 239000000612 proton pump inhibitor Substances 0.000 description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 15
- 239000008238 pharmaceutical water Substances 0.000 description 5
- -1 dontoprazole Chemical compound 0.000 description 3
- YREYEVIYCVEVJK-UHFFFAOYSA-N rabeprazole Chemical compound COCCCOC1=CC=NC(CS(=O)C=2NC3=CC=CC=C3N=2)=C1C YREYEVIYCVEVJK-UHFFFAOYSA-N 0.000 description 3
- 125000002619 bicyclic group Chemical group 0.000 description 2
- 239000003112 inhibitor Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229960004157 rabeprazole Drugs 0.000 description 2
- PSIREIZGKQBEEO-UHFFFAOYSA-N 2-(1h-benzimidazol-2-ylsulfinylmethyl)-n-methyl-n-(2-methylpropyl)aniline Chemical compound CC(C)CN(C)C1=CC=CC=C1CS(=O)C1=NC2=CC=CC=C2N1 PSIREIZGKQBEEO-UHFFFAOYSA-N 0.000 description 1
- CMZHQFXXAAIBKE-UHFFFAOYSA-N 5'-hydroxyomeprazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(CO)C(OC)=C1C CMZHQFXXAAIBKE-UHFFFAOYSA-N 0.000 description 1
- ZBFDAUIVDSSISP-UHFFFAOYSA-N 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]-1H-imidazo[4,5-b]pyridine Chemical compound N=1C2=NC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C ZBFDAUIVDSSISP-UHFFFAOYSA-N 0.000 description 1
- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 description 1
- IQPSEEYGBUAQFF-UHFFFAOYSA-N Pantoprazole Chemical compound COC1=CC=NC(CS(=O)C=2NC3=CC=C(OC(F)F)C=C3N=2)=C1OC IQPSEEYGBUAQFF-UHFFFAOYSA-N 0.000 description 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- SUBDBMMJDZJVOS-DEOSSOPVSA-N esomeprazole Chemical compound C([S@](=O)C1=NC2=CC=C(C=C2N1)OC)C1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-DEOSSOPVSA-N 0.000 description 1
- 229960004770 esomeprazole Drugs 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000012458 free base Substances 0.000 description 1
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Substances C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 description 1
- 125000002883 imidazolyl group Chemical group 0.000 description 1
- 229960003174 lansoprazole Drugs 0.000 description 1
- MJIHNNLFOKEZEW-UHFFFAOYSA-N lansoprazole Chemical compound CC1=C(OCC(F)(F)F)C=CN=C1CS(=O)C1=NC2=CC=CC=C2N1 MJIHNNLFOKEZEW-UHFFFAOYSA-N 0.000 description 1
- 229950007395 leminoprazole Drugs 0.000 description 1
- 229960000381 omeprazole Drugs 0.000 description 1
- 229960005019 pantoprazole Drugs 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000000651 prodrug Substances 0.000 description 1
- 229940002612 prodrug Drugs 0.000 description 1
- 125000000714 pyrimidinyl group Chemical group 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 229950008375 tenatoprazole Drugs 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48832403P | 2003-07-18 | 2003-07-18 | |
| PCT/US2004/023044 WO2005007117A2 (en) | 2003-07-18 | 2004-07-16 | Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006528182A JP2006528182A (ja) | 2006-12-14 |
| JP2006528182A5 true JP2006528182A5 (enExample) | 2011-02-17 |
Family
ID=34079415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006521149A Pending JP2006528182A (ja) | 2003-07-18 | 2004-07-16 | 薬学的製剤および酸に起因する消化器疾患の治療法 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20050031700A1 (enExample) |
| EP (1) | EP1648417A4 (enExample) |
| JP (1) | JP2006528182A (enExample) |
| AR (1) | AR045061A1 (enExample) |
| AU (2) | AU2004257864A1 (enExample) |
| CA (1) | CA2531566C (enExample) |
| MX (1) | MXPA06000524A (enExample) |
| TW (1) | TWI337877B (enExample) |
| WO (1) | WO2005007117A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1747776A1 (en) * | 2005-07-29 | 2007-01-31 | KRKA, tovarna zdravil, d.d., Novo mesto | Pharmaceutical composition comprising granular pantoprazole |
| US7351853B2 (en) * | 2006-01-23 | 2008-04-01 | Albion Advanced Nutrition | Method of manufacturing a granular mineral composition |
| AR056062A1 (es) | 2006-06-05 | 2007-09-19 | Bago Sa Labor | Composicion farmaceutica antiacida en forma de polvo, preparacion farmaceutica que la comprende y proceso para su preparacion |
| US20070292534A1 (en) * | 2006-06-15 | 2007-12-20 | Dennis Nelson | Antacid and breath freshening composition |
| MX2009004475A (es) | 2006-10-27 | 2009-08-12 | Univ Missouri | Composiciones que comprenden agentes acido labiles que inhiben la bomba de protones, por lo menos otro agente farmaceuticamente activo y metodos de uso de las misma. |
| US20080166423A1 (en) * | 2007-01-06 | 2008-07-10 | Renjit Sundharadas | Combination Medication for Treating the Effects of Stomach Acid Reduction Medication on Bone Integrity |
| CN101980700A (zh) | 2008-02-20 | 2011-02-23 | 密苏里大学董事会 | 包含奥美拉唑和兰索拉唑以及缓冲剂的组合的组合物及其使用方法 |
| WO2012020279A1 (en) * | 2010-08-13 | 2012-02-16 | Compagnie Gervais Danone | Product for the upper gastric sphere |
| CN103230413A (zh) * | 2013-01-10 | 2013-08-07 | 沈阳亿灵医药科技有限公司 | 复方奥美拉唑制剂 |
| GB2513172A (en) * | 2013-04-18 | 2014-10-22 | Nupharm Lab Ltd | Liquid dosage form and delivery system |
| MA42806A (fr) * | 2015-05-29 | 2018-07-25 | Johnson & Johnson Consumer Inc | Utilisation d'un extrait d'agrume organique à haute capacité antimicrobienne et de xylitol en tant que système de conservation dans des liquides, des émulsions, des suspensions, des crèmes et des antiacides |
| JP6184656B1 (ja) * | 2015-10-13 | 2017-08-23 | テクノガード株式会社 | 胃腸管粘膜保護組成物 |
| WO2017145146A1 (en) | 2016-02-25 | 2017-08-31 | Dexcel Pharma Technologies Ltd. | Compositions comprising proton pump inhibitors |
| US11207307B2 (en) | 2016-06-16 | 2021-12-28 | Azurity Pharmaceuticals, Inc. | Composition and method for proton pump inhibitor suspension |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| JP7069119B2 (ja) | 2016-08-11 | 2022-05-17 | アダミス ファーマシューティカルズ コーポレーション | 医薬組成物 |
| EP3720844A4 (en) | 2017-12-08 | 2021-08-11 | Adamis Pharmaceuticals Corporation | MEDICINAL COMPOSITIONS |
| GB2585628A (en) * | 2019-05-08 | 2021-01-20 | Alkaloid Ad | Pharmaceutical formulation |
| US11633478B2 (en) | 2019-07-16 | 2023-04-25 | Azurity Pharmaceuticals, Inc. | Compositions and kits for Omeprazole suspension |
| US10751333B1 (en) | 2019-07-16 | 2020-08-25 | Cutispharma, Inc. | Compositions and kits for omeprazole suspension |
| GB2631129A (en) | 2023-06-23 | 2024-12-25 | Orbit Pharma Ltd | A powder composition for oral suspension of proton pump inhibitors and the method of preparing the same |
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-
2004
- 2004-07-16 AR ARP040102531A patent/AR045061A1/es not_active Application Discontinuation
- 2004-07-16 JP JP2006521149A patent/JP2006528182A/ja active Pending
- 2004-07-16 MX MXPA06000524A patent/MXPA06000524A/es active IP Right Grant
- 2004-07-16 EP EP04778512A patent/EP1648417A4/en not_active Withdrawn
- 2004-07-16 CA CA2531566A patent/CA2531566C/en not_active Expired - Fee Related
- 2004-07-16 TW TW093121363A patent/TWI337877B/zh not_active IP Right Cessation
- 2004-07-16 WO PCT/US2004/023044 patent/WO2005007117A2/en not_active Ceased
- 2004-07-16 AU AU2004257864A patent/AU2004257864A1/en not_active Abandoned
- 2004-07-16 US US10/893,092 patent/US20050031700A1/en not_active Abandoned
-
2010
- 2010-07-30 US US12/847,938 patent/US20100297220A1/en not_active Abandoned
-
2011
- 2011-02-15 AU AU2011200642A patent/AU2011200642B2/en not_active Ceased
-
2014
- 2014-02-14 US US14/181,017 patent/US20140370104A1/en not_active Abandoned
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