JP2006525950A - ケミカルピーリングのための処方 - Google Patents
ケミカルピーリングのための処方 Download PDFInfo
- Publication number
- JP2006525950A JP2006525950A JP2005500189A JP2005500189A JP2006525950A JP 2006525950 A JP2006525950 A JP 2006525950A JP 2005500189 A JP2005500189 A JP 2005500189A JP 2005500189 A JP2005500189 A JP 2005500189A JP 2006525950 A JP2006525950 A JP 2006525950A
- Authority
- JP
- Japan
- Prior art keywords
- acid
- keratolytic agent
- keratolytic
- composition
- acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Detergent Compositions (AREA)
- Paints Or Removers (AREA)
Abstract
より好ましくは、本発明は、少なくとも1つの角質溶解剤とジメチルイソソルビドとを含むケミカルピーリングのための組成物である。
前記組成物は、さらにジメチルスルホンを含んでいてもよい。
Description
1.角質層からの死細胞の除去による細胞回転率の刺激。
a) 角化症および皮膚老化
b) 色素障害(Dischromia)
c) ポスト座瘡瘢痕
d) 一般的な座瘡および酒さ
e) 放射線皮膚炎
f) 伸展線
g) 脂漏性皮膚炎
様々な種類のケミカルピーリングは、以下のように分類され得る:
− 非常に表面的なピーリング:このタイプのピーリングは、表面的な角質層のみを除去する;
− 表面的なピーリング:このタイプのピーリングは、表皮の基底層に達する上皮層の一部または全ての壊死を引き起こす;
− 平均的深さのピーリング:このタイプのピーリングは、表皮および真皮乳頭層の一部の壊死を引き起こす;
− 深いピーリング:このタイプのピーリングは、表皮および真皮乳頭層の壊死を引き起こし、真皮網状層にまで及ぶ。
1.レチノイン酸
2.5-フルオロウラシル(5-Fu)
3.Jessnerの溶液
4.レゾルシン
5.サリチル酸
6.トリクロロ酢酸
7.α-ヒドロキシ酸
8.α-ケト酸(例えば、ピルビン酸)
9.フェノール
である。このような物質は、単独でまたは互いに関連して使用され得る。
角質表皮膜層(SCE)の調製は、文献に既に記述された技術を使用し、復元形成外科を受けた32〜45歳で構成される被験者由来のヒト皮膚のサンプルを使用して行われた。
処方GC1およびGC2からのグリコール酸のインビトロでの経皮吸収の程度の評価のために、一連の6つのFranzセル(LGA, Berkeley, CA)を使用した。各Franzセルは、「ドナー」と「レセプター」によって構成され、その間にSCE膜が静置されており、角質層が「ドナー」に面している。セルの「レセプター」の体積は、4.7mlであり、「ドナー」中の膜の表面積(すなわち、製品と接触する潜在的な皮膚表面積)は、0.75cm2であった。
処方GC1およびGC2の適用24時間後にFranzセルのレセプター相中に存在するグリコール酸の量の決定を、文献中に報告された適切なHPLC方法を使用して行った。
処方GC1およびGC2からのグリコール酸の皮膚浸透の研究において得られた結果(表1を参照)は、GC2処方が、SCE膜を横切って浸透したグリコール酸の量を、GC1処方と比べて2倍(p<0.01)にすることができることを実証した。
Claims (20)
- 少なくとも1つの角質溶解剤とジメチルイソソルビドとを含むケミカルピーリングのための組成物。
- 前記角質溶解剤(単独または2以上の角質溶解剤の混合物として)と前記ジメチルイソソルビドとを、それぞれ1重量%〜99重量%の量で含む請求項1に記載の組成物。
- 前記角質溶解剤(単独または2以上の角質溶解剤の混合物として)と前記ジメチルイソソルビドとを、それぞれ5%〜40%で構成された量で含む請求項2に記載の組成物。
- 前記角質溶解剤(単独または2以上の角質溶解剤の混合物として)と前記ジメチルイソソルビドとを、1:4〜4:1で構成された重量比で含む請求項1ないし3のいずれか1項に記載の組成物。
- 前記少なくとも1つの角質溶解剤が、飽和および不飽和のモノカルボン酸、飽和および不飽和のジカルボン酸、トリカルボン酸、モノカルボン酸のα-ヒドロキシ酸およびβ-ヒドロキシ酸、ジカルボン酸のα-ヒドロキシ酸およびβ-ヒドロキシ酸、トリカルボン酸のα-ヒドロキシ酸およびβ-ヒドロキシ酸、ケト酸、α-ケト酸、β-ケト酸、多カルボン酸、多ヒドロキシモノカルボン酸、多ヒドロキシジカルボン酸、多ヒドロキシトリカルボン酸、これらの塩、エステル、可能なシスまたはトランス形態、ラセミック混合物および/または相対的な右旋性または左旋性形態から選択される請求項1ないし4のいずれか1項に記載の組成物。
- 前記少なくとも1つの角質溶解剤が、グリコール酸、酒石酸、サリチル酸、クエン酸、乳酸、ピルビン酸、グルコン酸、グルクロン酸、リンゴ酸、シュウ酸、マロン酸、コハク酸、酢酸、フェノール、レゾルシン、レチノイン酸、アダパレン、トリクロロ酢酸、5-フルオロウラシル、アゼライン酸から選択される請求項5に記載の組成物。
- 化粧品学的または薬学的に許容可能な溶剤および/または化粧品学的または薬学的に許容可能な賦形剤をさらに含む請求項1ないし6のいずれか1項に記載の組成物。
- 前記溶剤が水、アルコールまたはグリコールから選択され、かつ前記賦形剤が乳化剤、酸化防止剤、脂質賦形剤、金属イオン封鎖剤、防腐剤から選択される請求項7に記載の組成物。
- 前記組成物が、ジメチルスルホンをさらに含む請求項1ないし8のいずれか1項に記載の組成物。
- 前記ジメチルスルホンを、角質溶解剤に対して2重量%〜70重量%で構成された量で含む請求項9に記載の組成物。
- 前記ジメチルスルホンを、角質溶解剤に対して10重量%〜65重量%で構成された量で含む請求項10に記載の組成物。
- 投与後に、治療のための部位の生物学的条件下で角質溶解剤を遊離することができる前記少なくとも1つの角質溶解剤の誘導体またはプロドラックをさらに含む請求項1ないし11のいずれか1項に記載の組成物。
- 前記誘導体またはプロドラックが、前記少なくとも1つの角質溶解剤のエステルであって、前記組成物中に使用された同じ角質溶解剤のエステルかまたは異なる角質溶解剤のエステルである請求項12に記載の組成物。
- 前記少なくとも1つの角質溶解剤の前記エステルが、ピルビン酸エチル、グリコール酸エチル、クエン酸トリエチル、レゾルシン酸エチル、レチノイン酸のエチルエステル、サリチル酸エチル、サリチル酸メチル、マロン酸エチル、酢酸エチル、酒石酸エチルから選択される請求項13に記載の組成物。
- 前記少なくとも1つの角質溶解剤の前記誘導体またはプロドラッグを、角質溶解剤に対して3重量%〜60重量%で構成された量で含む請求項12ないし14のいずれか1項に記載の組成物。
- 前記少なくとも1つの角質溶解剤の前記誘導体またはプロドラッグを、角質溶解剤に対して15重量%〜50重量%で構成された量で含む請求項12ないし14のいずれか1項に記載の組成物。
- 角質溶解剤を含むケミカルピーリングのための組成物の調製のためのジメチルイソソルビドの使用であって、前記角質溶解剤の吸収速度を増加させるための使用。
- ケミカルピーリングのための組成物の調製におけるジメチルスルホンの使用であって、抗炎症剤、抗刺激剤および抗紅斑剤としての使用。
- 少なくとも1つの角質溶解剤と、投与後に、治療のための部位の生物学的条件下で角質溶解剤を遊離することができる角質溶解剤の誘導体またはプロドラッグとを含むケミカルピーリングのための組成物。
- 前記誘導体またはプロドラッグが、角質溶解剤のエステルである請求項19に記載の組成物。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IT2003/000339 WO2004105722A1 (en) | 2003-05-30 | 2003-05-30 | A formulation for chemical peeling |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008147301A Division JP2008291032A (ja) | 2008-06-04 | 2008-06-04 | ケミカルピーリングのための処方 |
JP2008278702A Division JP2009137939A (ja) | 2008-10-29 | 2008-10-29 | ケミカルピーリングのための処方 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2006525950A true JP2006525950A (ja) | 2006-11-16 |
JP4260163B2 JP4260163B2 (ja) | 2009-04-30 |
Family
ID=33485484
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005500189A Expired - Fee Related JP4260163B2 (ja) | 2003-05-30 | 2003-05-30 | ケミカルピーリングのための処方 |
Country Status (11)
Country | Link |
---|---|
US (1) | US20070010580A1 (ja) |
EP (2) | EP1631248A1 (ja) |
JP (1) | JP4260163B2 (ja) |
CN (1) | CN1771021B (ja) |
AU (1) | AU2003238685B2 (ja) |
CA (1) | CA2525691C (ja) |
ES (1) | ES2672202T3 (ja) |
HR (1) | HRP20050972B1 (ja) |
TR (1) | TR201807182T4 (ja) |
TW (1) | TWI333854B (ja) |
WO (1) | WO2004105722A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006282626A (ja) * | 2005-04-04 | 2006-10-19 | Anpurii:Kk | ピーリング剤組成物 |
JP2010533689A (ja) * | 2007-07-16 | 2010-10-28 | ロレアル | L−アミノ酸オキシダーゼを活性化する緑色光の使用 |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004037225A2 (en) | 2002-10-25 | 2004-05-06 | Foamix Ltd. | Cosmetic and pharmaceutical foam |
IL152486A0 (en) | 2002-10-25 | 2003-05-29 | Meir Eini | Alcohol-free cosmetic and pharmaceutical foam carrier |
US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
US20050205086A1 (en) * | 2002-10-25 | 2005-09-22 | Foamix Ltd. | Retinoid immunomodulating kit and composition and uses thereof |
US20080138296A1 (en) * | 2002-10-25 | 2008-06-12 | Foamix Ltd. | Foam prepared from nanoemulsions and uses |
US7704518B2 (en) | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
US10117812B2 (en) * | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
US20060233721A1 (en) * | 2002-10-25 | 2006-10-19 | Foamix Ltd. | Foam containing unique oil globules |
US20070292359A1 (en) * | 2002-10-25 | 2007-12-20 | Foamix Ltd. | Polypropylene glycol foamable vehicle and pharmaceutical compositions thereof |
US8900554B2 (en) | 2002-10-25 | 2014-12-02 | Foamix Pharmaceuticals Ltd. | Foamable composition and uses thereof |
US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
US9668972B2 (en) * | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
US20080031907A1 (en) * | 2002-10-25 | 2008-02-07 | Foamix Ltd. | Cosmetic and pharmaceutical foam |
US20050271596A1 (en) * | 2002-10-25 | 2005-12-08 | Foamix Ltd. | Vasoactive kit and composition and uses thereof |
US7700076B2 (en) | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
US20060018937A1 (en) * | 2002-10-25 | 2006-01-26 | Foamix Ltd. | Steroid kit and foamable composition and uses thereof |
US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
ES2672202T3 (es) * | 2003-05-30 | 2018-06-13 | Gianfranco De Paoli Ambrosi | Uso de dimetil-sulfona en formulaciones para desprendimiento químico |
US20120094965A1 (en) * | 2003-05-30 | 2012-04-19 | Gianfranco De Paoli Ambrosi | Method and Formulation for Chemical Peeling |
US8795693B2 (en) * | 2003-08-04 | 2014-08-05 | Foamix Ltd. | Compositions with modulating agents |
EP1670435A2 (en) * | 2003-08-04 | 2006-06-21 | Foamix Ltd. | Foam carrier containing amphiphilic copolymeric gelling agent |
JP2005310310A (ja) * | 2004-04-23 | 2005-11-04 | Sanyo Electric Co Ltd | トラッキングバランス調整装置 |
FR2885536B1 (fr) * | 2005-05-12 | 2007-07-27 | Roquette Freres | Composition a base d'ethers de dianhydrohexitol pour le traitement d'une matiere autre que le corps humain |
US20080152596A1 (en) * | 2005-07-19 | 2008-06-26 | Foamix Ltd. | Polypropylene glycol foamable vehicle and pharmaceutical compositions thereof |
US7709014B2 (en) * | 2005-10-17 | 2010-05-04 | Yu Ruey J | Hydroxy-oligocarboxylic esters: effects on nerve and use for cutaneous and mucocutaneous organs or sites |
EP1867318A1 (en) * | 2006-06-13 | 2007-12-19 | Wella Aktiengesellschaft | Body Care composition with water-soluble abrasive particles |
MX2009002536A (es) * | 2006-09-08 | 2009-04-14 | Foamix Ltd | Composicion espumable coloreada o coloreable y espuma. |
US20080260655A1 (en) * | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
US20080292560A1 (en) * | 2007-01-12 | 2008-11-27 | Dov Tamarkin | Silicone in glycol pharmaceutical and cosmetic compositions with accommodating agent |
US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
US9439857B2 (en) * | 2007-11-30 | 2016-09-13 | Foamix Pharmaceuticals Ltd. | Foam containing benzoyl peroxide |
WO2009090495A2 (en) | 2007-12-07 | 2009-07-23 | Foamix Ltd. | Oil and liquid silicone foamable carriers and formulations |
FR2927800A1 (fr) * | 2008-02-25 | 2009-08-28 | Oreal | Association d'un rayonnement lumineux et d'un compose bioconvertible par la lipase pour ameliorer l'apparence de la peau et/ou du cheveu. |
FR2941377B1 (fr) * | 2009-01-29 | 2013-02-15 | Soliance | Compositions cosmetiques comprenant des derives d'acide cetogluconique |
CA2760186C (en) | 2009-04-28 | 2019-10-29 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
WO2011013008A2 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
WO2011013009A2 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
NL2003419C2 (en) * | 2009-09-01 | 2011-03-02 | Shieldmark Zacco | Composition for tropical application, uses thereof, applicator device and kit of parts. |
US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
WO2011064631A1 (en) | 2009-10-02 | 2011-06-03 | Foamix Ltd. | Surfactant-free, water-free, foamable compositions and breakable foams and their uses |
EP2537512A3 (en) * | 2011-04-19 | 2015-12-02 | Gianfranco De Paoli Ambrosi | Method and formulation for chemical peeling |
GB2507639B (en) * | 2012-09-10 | 2019-02-13 | Ad Lunam Labs Inc | Antifungal serum comprising alkyl lactate and simmondsia chinesis seed oil |
ES2770523T3 (es) * | 2013-08-09 | 2020-07-01 | Chemours Co Fc Llc | Composiciones para el cuidado de la piel que tienen diésteres cíclicos y métodos de las mismas |
MX2020012139A (es) | 2016-09-08 | 2021-01-29 | Vyne Pharmaceuticals Inc | Composiciones y metodos para tratar rosacea y acne. |
HRP20231153T1 (hr) * | 2018-04-09 | 2024-01-05 | Noon Aesthetics M.R Ltd. | Topikalne formulacije koje sadrže stroncij i metilsulfonilmetan (msm) i njihova primjena za tretman kože |
CN116492240B (zh) * | 2023-06-30 | 2023-09-19 | 北京大学第三医院(北京大学第三临床医学院) | 一种含有巴瑞替尼的复方化学剥脱换肤试剂及其用途 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2452119A1 (de) * | 1974-11-02 | 1976-05-13 | Henkel & Cie Gmbh | Kosmetische zubereitungen fuer die behandlung von akne |
US4082881A (en) * | 1976-12-23 | 1978-04-04 | E. R. Squibb & Sons, Inc. | Topical and other type pharmaceutical formulations containing isosorbide carrier |
US5166176A (en) * | 1986-12-29 | 1992-11-24 | Obagi Zein E | Composition for healing damaged skin |
GB9218701D0 (en) * | 1992-09-04 | 1992-10-21 | Salim Aws S M | Housewife dermatitis treatment |
WO1997009027A1 (en) * | 1995-09-01 | 1997-03-13 | Isp Investments Inc. | Cosmetic composition of an alpha or beta-hydroxy acid and a polyvinylpyrrolidone complexing agent |
US5824326A (en) * | 1997-06-27 | 1998-10-20 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Activity enhancement of ferulic acid with dimethyl isosorbride in cosmetic compositions |
US7074747B1 (en) * | 1999-07-01 | 2006-07-11 | Johnson & Johnson Consumer Companies, Inc. | Cleansing compositions |
FR2813528B1 (fr) * | 2000-09-07 | 2004-02-27 | Oreal | Composition cosmetique, et son utilisation comme masque de nettoyage de la peau |
AU2000274827A1 (en) * | 2000-09-13 | 2002-03-26 | The Procter And Gamble Company | Cosmetic compositions |
DE10055558A1 (de) * | 2000-11-09 | 2002-06-06 | Henkel Kgaa | Kosmetische Zusammensetzung zur Behandlung, zur Pflege oder zum Schutz der Haut |
AU2001224380A1 (en) * | 2000-12-18 | 2002-07-01 | The Procter And Gamble Company | Wet wipe |
US20030114562A1 (en) * | 2001-06-27 | 2003-06-19 | Pennzoil-Quaker State Company | Tinting composition and method of use |
HUP0104831A2 (hu) * | 2001-10-19 | 2003-08-28 | Torrent Pharmaceuticals Ltd. | Készítmény és eljárás piridíniumszármazékok gyógyászati alkalmazására |
US20030194385A1 (en) * | 2002-01-29 | 2003-10-16 | Lila Gruber Research Foundation | Pharmaceutical formulations containing solubilized hydroquinone, salicylic acid and hydrocortisone for the treatment of melasma and related dermatological problems |
ES2322345T3 (es) * | 2003-05-30 | 2009-06-19 | Gianfranco De Paoli Ambrosi | Composicion cosmetica y/o farmaceutica que comprende dimetil sulfona y filtro solar para la cura y prevencion de irritaciones, inflamaciones y eritemas cutaneos. |
ES2672202T3 (es) * | 2003-05-30 | 2018-06-13 | Gianfranco De Paoli Ambrosi | Uso de dimetil-sulfona en formulaciones para desprendimiento químico |
-
2003
- 2003-05-30 ES ES10181232.9T patent/ES2672202T3/es not_active Expired - Lifetime
- 2003-05-30 TR TR2018/07182T patent/TR201807182T4/tr unknown
- 2003-05-30 CN CN038265567A patent/CN1771021B/zh not_active Expired - Fee Related
- 2003-05-30 WO PCT/IT2003/000339 patent/WO2004105722A1/en active Application Filing
- 2003-05-30 AU AU2003238685A patent/AU2003238685B2/en not_active Ceased
- 2003-05-30 CA CA2525691A patent/CA2525691C/en not_active Expired - Fee Related
- 2003-05-30 US US10/557,923 patent/US20070010580A1/en not_active Abandoned
- 2003-05-30 EP EP03733016A patent/EP1631248A1/en not_active Ceased
- 2003-05-30 JP JP2005500189A patent/JP4260163B2/ja not_active Expired - Fee Related
- 2003-05-30 EP EP10181232.9A patent/EP2269615B1/en not_active Expired - Lifetime
-
2004
- 2004-05-20 TW TW093114247A patent/TWI333854B/zh not_active IP Right Cessation
-
2005
- 2005-11-29 HR HRP20050972AA patent/HRP20050972B1/hr not_active IP Right Cessation
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006282626A (ja) * | 2005-04-04 | 2006-10-19 | Anpurii:Kk | ピーリング剤組成物 |
JP4565639B2 (ja) * | 2005-04-04 | 2010-10-20 | 株式会社アンプリー | ピーリング剤組成物 |
JP2010533689A (ja) * | 2007-07-16 | 2010-10-28 | ロレアル | L−アミノ酸オキシダーゼを活性化する緑色光の使用 |
US9750675B2 (en) | 2007-07-16 | 2017-09-05 | L'oreal | Use of green light to activate L-amino acid oxidase |
Also Published As
Publication number | Publication date |
---|---|
CA2525691A1 (en) | 2004-12-09 |
HRP20050972B1 (hr) | 2013-09-30 |
AU2003238685A1 (en) | 2005-01-21 |
WO2004105722A8 (en) | 2005-02-10 |
US20070010580A1 (en) | 2007-01-11 |
AU2003238685B2 (en) | 2009-10-08 |
HRP20050972A2 (en) | 2006-09-30 |
WO2004105722A1 (en) | 2004-12-09 |
ES2672202T3 (es) | 2018-06-13 |
TR201807182T4 (tr) | 2018-06-21 |
TW200505411A (en) | 2005-02-16 |
EP2269615A1 (en) | 2011-01-05 |
TWI333854B (en) | 2010-12-01 |
EP1631248A1 (en) | 2006-03-08 |
CN1771021B (zh) | 2011-11-16 |
CN1771021A (zh) | 2006-05-10 |
JP4260163B2 (ja) | 2009-04-30 |
CA2525691C (en) | 2012-01-24 |
EP2269615B1 (en) | 2018-03-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP4260163B2 (ja) | ケミカルピーリングのための処方 | |
CA1228812A (en) | Process for the manufacture of novel topically administrable pharmaceutical compositions | |
Polano | Dependence of corticosteroid penetration on the vehicle | |
JP4564471B2 (ja) | 外用に適する組成物 | |
US20130202650A1 (en) | Topical composition comprising a combination of at least two penetration enhancing agents | |
CA2135598A1 (en) | Anhydrous formulations for administering lipophilic agents | |
FR2591105A1 (fr) | Composition pharmaceutique, notamment dermatologique, ou cosmetique, a base de phases lamellaires lipidiques hydratees ou de liposomes contenant un retinoide ou un analogue structural dudit retinoide tel qu'un carotenoide. | |
FR2502951A1 (fr) | Compositions pharmaceutiques topiques sous forme d'une micro-emulsion | |
KR20080008321A (ko) | 국소 젤 조성물 | |
EP1716845B1 (de) | Formulierung zur dermalen Anwendung | |
JP2013515020A (ja) | 溶媒混合物およびビタミンd誘導体から成る医薬品組成物または類似体 | |
JP2015518033A (ja) | レチノイドを含むo/w−エマルジョン型局所医薬組成物 | |
JP2009137939A (ja) | ケミカルピーリングのための処方 | |
RU2313334C2 (ru) | Состав для химического пилинга | |
JP2008291032A (ja) | ケミカルピーリングのための処方 | |
CN115531226A (zh) | 一种甘草酸-甘草查尔酮a胶束乳液制备方法及美白应用 | |
FR2686251A1 (fr) | Composition pour la cicatrisation d'une plaie. | |
ZA200509283B (en) | A formulation for chemical peeling | |
RU2495660C1 (ru) | Комбинированная мазевая композиция с репарирующим эффектом | |
WO2018100510A1 (en) | Composition comprising glutathion tioester and secoiridoids of the plant olea europea for treating hair loss | |
US20140221474A1 (en) | Method and Formulation for Chemical Peeling | |
RU2624238C2 (ru) | Лечение себореи | |
WO2024013283A1 (fr) | Nouveau regime posologique d'une composition comprenant de la brimonidine pour son utilisation dans la prevention et le traitement des dommages cutanes resultant d'un rayonnement | |
EP4401732A1 (en) | Compositions and formulations for topical use of an akt inhibitor for the prevention, treatment, and improvement of skin diseases, conditions, and disorders | |
JP2009235065A (ja) | 経皮吸収促進剤、並びにこれを含有する皮膚処理用製剤及び経皮吸収型製剤 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20071126 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20071204 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20080225 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20080303 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20080604 |
|
A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20080701 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20081029 |
|
A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20081208 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20090106 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20090203 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20120220 Year of fee payment: 3 |
|
R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130220 Year of fee payment: 4 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130220 Year of fee payment: 4 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
LAPS | Cancellation because of no payment of annual fees |