JP2006525328A5 - - Google Patents
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- Publication number
- JP2006525328A5 JP2006525328A5 JP2006509943A JP2006509943A JP2006525328A5 JP 2006525328 A5 JP2006525328 A5 JP 2006525328A5 JP 2006509943 A JP2006509943 A JP 2006509943A JP 2006509943 A JP2006509943 A JP 2006509943A JP 2006525328 A5 JP2006525328 A5 JP 2006525328A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- combination
- cardiovascular disease
- prevention
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 208000024172 Cardiovascular disease Diseases 0.000 claims 8
- 238000000034 method Methods 0.000 claims 6
- 230000002265 prevention Effects 0.000 claims 6
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 claims 5
- 229960001138 acetylsalicylic acid Drugs 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- 239000002207 metabolite Substances 0.000 claims 4
- 239000000651 prodrug Substances 0.000 claims 4
- 229940002612 prodrug Drugs 0.000 claims 4
- 239000012453 solvate Substances 0.000 claims 4
- 208000004476 Acute Coronary Syndrome Diseases 0.000 claims 3
- 230000000747 cardiac effect Effects 0.000 claims 3
- 206010003658 Atrial Fibrillation Diseases 0.000 claims 2
- 206010019280 Heart failures Diseases 0.000 claims 2
- 208000026106 cerebrovascular disease Diseases 0.000 claims 2
- 208000019553 vascular disease Diseases 0.000 claims 2
- 206010002329 Aneurysm Diseases 0.000 claims 1
- 208000009447 Cardiac Edema Diseases 0.000 claims 1
- 208000006017 Cardiac Tamponade Diseases 0.000 claims 1
- 206010007513 Cardiac aneurysm Diseases 0.000 claims 1
- 206010007559 Cardiac failure congestive Diseases 0.000 claims 1
- 206010011086 Coronary artery occlusion Diseases 0.000 claims 1
- 208000000059 Dyspnea Diseases 0.000 claims 1
- 206010013975 Dyspnoeas Diseases 0.000 claims 1
- 208000010496 Heart Arrest Diseases 0.000 claims 1
- 208000035211 Heart Murmurs Diseases 0.000 claims 1
- 208000000616 Hemoptysis Diseases 0.000 claims 1
- 206010033799 Paralysis Diseases 0.000 claims 1
- 208000001871 Tachycardia Diseases 0.000 claims 1
- JALHGCPDPSNJNY-UHFFFAOYSA-N [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4h-thieno[3,2-c]pyridin-2-yl] acetate;hydron;chloride Chemical compound Cl.C1CC=2SC(OC(=O)C)=CC=2CN1C(C=1C(=CC=CC=1)F)C(=O)C1CC1 JALHGCPDPSNJNY-UHFFFAOYSA-N 0.000 claims 1
- 229940045200 cardioprotective agent Drugs 0.000 claims 1
- 239000012659 cardioprotective agent Substances 0.000 claims 1
- 230000002107 myocardial effect Effects 0.000 claims 1
- 208000010125 myocardial infarction Diseases 0.000 claims 1
- 208000021090 palsy Diseases 0.000 claims 1
- 239000003223 protective agent Substances 0.000 claims 1
- 208000037803 restenosis Diseases 0.000 claims 1
- 206010042772 syncope Diseases 0.000 claims 1
- 230000006794 tachycardia Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46790303P | 2003-05-05 | 2003-05-05 | |
| PCT/US2004/011257 WO2004098713A2 (en) | 2003-05-05 | 2004-04-26 | Treating cardiovascular diseases with a compound of formula (i) (cs 747 - prasugrel; rn 150322-43-4) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006525328A JP2006525328A (ja) | 2006-11-09 |
| JP2006525328A5 true JP2006525328A5 (enExample) | 2007-01-18 |
Family
ID=33435139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509943A Pending JP2006525328A (ja) | 2003-05-05 | 2004-04-26 | 心疾患の治療方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20060217351A1 (enExample) |
| EP (1) | EP1660183A2 (enExample) |
| JP (1) | JP2006525328A (enExample) |
| WO (1) | WO2004098713A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8137397B2 (en) * | 2004-02-26 | 2012-03-20 | Boston Scientific Scimed, Inc. | Medical devices |
| CN101198329A (zh) * | 2005-06-17 | 2008-06-11 | 伊莱利利公司 | 普拉格雷给药方案 |
| EP1940399A2 (en) * | 2005-08-19 | 2008-07-09 | Eli Lilly & Company | Use of par-i/par- 4 inhibitors for treating or preventing vascular diseases |
| EP2032521B1 (en) * | 2006-06-27 | 2009-10-28 | Sandoz AG | New method for salt preparation |
| US20090291138A1 (en) * | 2006-12-07 | 2009-11-26 | Daiichi Sankyo Company, Limited | Film-coated preparation having improved stability |
| US20110201814A1 (en) | 2006-12-07 | 2011-08-18 | Daiichi Sankyo Company Limited | Method for producing solid preparation |
| CA2672134C (en) | 2006-12-07 | 2015-02-10 | Daiichi Sankyo Company, Limited | Solid medicinal preparation containing mannitol or lactose |
| KR101647842B1 (ko) | 2006-12-07 | 2016-08-11 | 다이이찌 산쿄 가부시키가이샤 | 저장 안정성이 개선된 의약 조성물 |
| CN101594865A (zh) | 2006-12-07 | 2009-12-02 | 第一三共株式会社 | 含有低取代的羟基丙基纤维素的药物组合物 |
| JP5363307B2 (ja) * | 2007-03-02 | 2013-12-11 | 第一三共株式会社 | 高純度のプラスグレル塩酸塩の製造方法 |
| RU2470636C2 (ru) | 2007-04-27 | 2012-12-27 | Сайдекс Фамэсьютиклз, Инк. | Композиция клопидогреля и сульфоалкилового эфира циклодекстрина (варианты) и способы лечения заболеваний посредством названной композиции (варианты) |
| US20100261908A1 (en) * | 2007-11-09 | 2010-10-14 | Dr. Reddy's Laboratories Ltd. | Processes for the preparation of prasugrel , and its salts and polymorphs |
| HU230262B1 (hu) * | 2007-11-27 | 2015-11-30 | Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság | Eljárás gyógyszeripari intermedierek előállítására |
| US20090281136A1 (en) * | 2008-05-08 | 2009-11-12 | Sandeep Mhetre | Prasugrel pharmaceutical formulations |
| WO2010094471A1 (en) * | 2009-02-17 | 2010-08-26 | Krka, D. D., Novo Mesto | Pharmaceutical compositions comprising prasugrel base or its pharmaceutically acceptable acid addition salts and processes for their preparation |
| DK3100728T3 (da) | 2009-05-13 | 2020-02-17 | Cydex Pharmaceuticals Inc | Farmaceutiske sammensætninger omfattende prasugrel og cyclodextrin-derivativ og fremgangsmåder til fremstilling og brug af samme |
| DK2470165T3 (en) * | 2009-08-28 | 2018-06-06 | Hercules Llc | FILM COATING COMPOSITION OF SOLID POWDER COMPOUNDS |
| EP2275087B8 (en) * | 2010-02-22 | 2012-11-21 | Jrs Pharma GmbH+Co.kG | Prasugrel controlled release formulations |
| WO2011110219A1 (en) | 2010-03-09 | 2011-09-15 | Synthon Bv | A process for making prasugrel |
| TR201006802A1 (tr) * | 2010-08-17 | 2012-03-21 | Sanovel İlaç San. Ve Ti̇c. A.Ş. | Prasugrelin oral yolla dağılan formülasyonları. |
| EP2409685A3 (en) * | 2010-07-19 | 2012-02-01 | Sanovel Ilac Sanayi ve Ticaret A.S. | Orally-disintegrating formulations of prasugrel |
| CN102775422B (zh) * | 2012-03-13 | 2014-12-31 | 山东新华制药股份有限公司 | 普拉格雷中间体的一种晶型 |
| CN102993210A (zh) * | 2012-12-19 | 2013-03-27 | 苏春华 | 一种吡啶并噻吩的新化合物 |
| CN104418718B (zh) * | 2013-08-28 | 2018-04-13 | 山东新时代药业有限公司 | 一种环丙基‑2‑溴‑2‑（2‑氟苯基）乙酮的制备方法 |
| CN107304216A (zh) * | 2016-04-20 | 2017-10-31 | 陕西合成药业股份有限公司 | 噻吩吡啶类衍生物及其制备方法和用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997049397A1 (en) * | 1996-06-26 | 1997-12-31 | Sankyo Company, Limited | Novel medicinal compositions of hydropyridines |
| JP3274088B2 (ja) * | 1996-08-28 | 2002-04-15 | 三共株式会社 | 環状アミン誘導体 |
| JP3907029B2 (ja) * | 1998-02-27 | 2007-04-18 | 三共株式会社 | 環状アミン誘導体を含有する医薬 |
| US6509348B1 (en) * | 1998-11-03 | 2003-01-21 | Bristol-Myers Squibb Company | Combination of an ADP-receptor blocking antiplatelet drug and a thromboxane A2 receptor antagonist and a method for inhibiting thrombus formation employing such combination |
| JP2001131067A (ja) * | 1999-08-26 | 2001-05-15 | Sankyo Co Ltd | 血小板凝集抑制剤又は動脈硬化進展抑制剤 |
| WO2001044239A2 (en) * | 1999-12-15 | 2001-06-21 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| EP1298132B1 (en) * | 2000-07-06 | 2006-11-22 | Sankyo Company, Limited | Hydropyridine derivative acid addition salts |
| JP4001199B2 (ja) * | 2000-07-06 | 2007-10-31 | 第一三共株式会社 | ヒドロピリジン誘導体酸付加塩 |
| CN100341506C (zh) * | 2000-12-25 | 2007-10-10 | 三共株式会社 | 含有阿斯匹林的药用组合物 |
| JP2002348235A (ja) * | 2001-03-23 | 2002-12-04 | Clinical Supply:Kk | 再狭窄予防剤 |
-
2004
- 2004-04-26 JP JP2006509943A patent/JP2006525328A/ja active Pending
- 2004-04-26 EP EP04750031A patent/EP1660183A2/en not_active Withdrawn
- 2004-04-26 WO PCT/US2004/011257 patent/WO2004098713A2/en not_active Ceased
- 2004-04-26 US US10/553,763 patent/US20060217351A1/en not_active Abandoned
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