JP2006525315A5 - - Google Patents
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- Publication number
- JP2006525315A5 JP2006525315A5 JP2006507485A JP2006507485A JP2006525315A5 JP 2006525315 A5 JP2006525315 A5 JP 2006525315A5 JP 2006507485 A JP2006507485 A JP 2006507485A JP 2006507485 A JP2006507485 A JP 2006507485A JP 2006525315 A5 JP2006525315 A5 JP 2006525315A5
- Authority
- JP
- Japan
- Prior art keywords
- dosage form
- active agent
- agent component
- barrier
- transdermal dosage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000013543 active substance Substances 0.000 claims 14
- 239000006211 transdermal dosage form Substances 0.000 claims 11
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 8
- 230000004888 barrier function Effects 0.000 claims 8
- 230000002411 adverse Effects 0.000 claims 7
- 239000003795 chemical substances by application Substances 0.000 claims 7
- 239000002552 dosage form Substances 0.000 claims 5
- 239000002904 solvent Substances 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 4
- 239000000463 material Substances 0.000 claims 3
- 239000005557 antagonist Substances 0.000 claims 2
- 238000009792 diffusion process Methods 0.000 claims 2
- 239000011324 bead Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- PJMPHNIQZUBGLI-UHFFFAOYSA-N fentanyl Chemical compound C=1C=CC=CC=1N(C(=O)CC)C(CC1)CCN1CCC1=CC=CC=C1 PJMPHNIQZUBGLI-UHFFFAOYSA-N 0.000 claims 1
- 229960002428 fentanyl Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000002195 soluble material Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 230000037317 transdermal delivery Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46724303P | 2003-04-30 | 2003-04-30 | |
| US10/744,966 US20040219195A1 (en) | 2003-04-30 | 2003-12-23 | Abuse-resistant transdermal dosage form |
| PCT/US2004/008856 WO2004098568A2 (en) | 2003-04-30 | 2004-03-23 | Tamper-resistant transdermal dosage form comprising an active agent component and an adverse agent component at the distal site of the active agent layer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012064165A Division JP2012140453A (ja) | 2003-04-30 | 2012-03-21 | 活性薬剤構成要素および活性薬剤層の遠位に逆作用薬剤構成要素を含んでなる不正使用防止機能付き経皮的剤形 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006525315A JP2006525315A (ja) | 2006-11-09 |
| JP2006525315A5 true JP2006525315A5 (https=) | 2007-05-10 |
Family
ID=33313652
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006507485A Pending JP2006525315A (ja) | 2003-04-30 | 2004-03-23 | 活性薬剤構成要素および活性薬剤層の遠位に逆作用薬剤構成要素を含んでなる不正使用防止機能付き経皮的剤形 |
| JP2012064165A Pending JP2012140453A (ja) | 2003-04-30 | 2012-03-21 | 活性薬剤構成要素および活性薬剤層の遠位に逆作用薬剤構成要素を含んでなる不正使用防止機能付き経皮的剤形 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012064165A Pending JP2012140453A (ja) | 2003-04-30 | 2012-03-21 | 活性薬剤構成要素および活性薬剤層の遠位に逆作用薬剤構成要素を含んでなる不正使用防止機能付き経皮的剤形 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20040219195A1 (https=) |
| EP (1) | EP1651196B1 (https=) |
| JP (2) | JP2006525315A (https=) |
| AT (1) | ATE423551T1 (https=) |
| AU (2) | AU2004237579A1 (https=) |
| CA (1) | CA2523709A1 (https=) |
| DE (1) | DE602004019653D1 (https=) |
| ES (1) | ES2322154T3 (https=) |
| WO (1) | WO2004098568A2 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8790689B2 (en) * | 2003-04-30 | 2014-07-29 | Purdue Pharma L.P. | Tamper resistant transdermal dosage form |
| KR101159828B1 (ko) * | 2003-04-30 | 2012-07-04 | 퍼듀 퍼머 엘피 | 활성제 구성요소 및 활성제 층의 원위부에 억제제 구성요소를 포함하는 내변조성 경피제형 |
| CN101232875B (zh) | 2005-06-10 | 2014-06-25 | 3M创新有限公司 | 处理粘合层叠片片段的方法 |
| BRPI0619806A2 (pt) * | 2005-12-13 | 2011-10-18 | Biodelivery Sciences Int Inc | dispositivo para fornecimento de fármacos transmucosal resistente ao abuso |
| US7740879B2 (en) * | 2006-01-17 | 2010-06-22 | Harrogate Holdings | Abuse resistant transdermal drug delivery patch |
| DE102006025282A1 (de) | 2006-05-31 | 2007-12-20 | Lts Lohmann Therapie-Systeme Ag | Selbstzerstörendes transdermales therapeutisches System |
| RU2504377C2 (ru) | 2006-07-21 | 2014-01-20 | БайоДеливери Сайенсиз Интэнэшнл, Инк. | Способ трансмукозальной доставки лекарства, средство трансмукозальной доставки лекарства (варианты) и способ лечения боли |
| WO2008073576A1 (en) * | 2006-12-08 | 2008-06-19 | Alcon, Inc. | Drug delivery device |
| EP2259780A2 (en) | 2008-02-28 | 2010-12-15 | Syntropharma Limited | Pharmaceutical composition comprising naltrexone |
| JP5386205B2 (ja) * | 2009-03-19 | 2014-01-15 | リンテック株式会社 | 経皮吸収型貼付剤 |
| JP2013524275A (ja) * | 2010-04-03 | 2013-06-17 | ドシ,プラフル | 薬剤を含む医療機器、その製造方法とその使用方法 |
| MX352959B (es) | 2011-08-18 | 2017-12-15 | Biodelivery Sciences Int Inc | Dispositivos mucoadhesivos resistentes al abuso para el suministro de buprenorfina. |
| US9901539B2 (en) | 2011-12-21 | 2018-02-27 | Biodelivery Sciences International, Inc. | Transmucosal drug delivery devices for use in chronic pain relief |
| WO2013148506A1 (en) * | 2012-03-30 | 2013-10-03 | 3M Innovative Properties Company | Urea-based and urethane-based pressure sensitive adhesive blends |
| US9950106B2 (en) | 2012-12-05 | 2018-04-24 | Cook Medical Technologies Llc | Antimicrobial barrier device |
| CN115444659A (zh) * | 2014-01-22 | 2022-12-09 | 4P治疗公司 | 滥用和误用制止透皮系统 |
| WO2016099986A2 (en) | 2014-12-18 | 2016-06-23 | 3M Innovative Properties Company | Methods of handling adhesive laminate patches |
| US10010543B1 (en) | 2014-12-23 | 2018-07-03 | Barr Laboratories, Inc. | Transdermal dosage form |
| CN107613853A (zh) | 2015-01-23 | 2018-01-19 | 马尔西奥·马克·阿布雷乌 | 用于皮肤处理的设备和方法 |
| CN110470607B (zh) * | 2018-05-09 | 2021-12-07 | 江苏集萃智能液晶科技有限公司 | 一种检测混合溶液中亲水性有机溶剂含量的方法 |
| WO2020008370A1 (en) * | 2018-07-02 | 2020-01-09 | Clexio Biosciences Ltd. | Transdermal patch |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1602344A (en) * | 1924-01-09 | 1926-10-05 | Eagle Peter | Medicating compress |
| US2807262A (en) * | 1952-12-10 | 1957-09-24 | Robert B Lew | Perforated plastic adhesive tape bandage |
| US3773955A (en) * | 1970-08-03 | 1973-11-20 | Bristol Myers Co | Analgetic compositions |
| US4457933A (en) * | 1980-01-24 | 1984-07-03 | Bristol-Myers Company | Prevention of analgesic abuse |
| US4539256A (en) * | 1982-09-09 | 1985-09-03 | Minnesota Mining And Manufacturing Co. | Microporous sheet material, method of making and articles made therewith |
| US4693776A (en) * | 1985-05-16 | 1987-09-15 | Minnesota Mining And Manufacturing Company | Macromer reinforced pressure sensitive skin adhesive |
| US4666441A (en) * | 1985-12-17 | 1987-05-19 | Ciba-Geigy Corporation | Multicompartmentalized transdermal patches |
| US4743249A (en) * | 1986-02-14 | 1988-05-10 | Ciba-Geigy Corp. | Dermal and transdermal patches having a discontinuous pattern adhesive layer |
| DE3634016A1 (de) * | 1986-04-17 | 1987-10-29 | Lohmann Gmbh & Co Kg | Flaechenfoermiges therapeutisches system, verfahren zu seiner herstellung und seine verwendung |
| US4917688A (en) * | 1987-01-14 | 1990-04-17 | Nelson Research & Development Co. | Bandage for transdermal delivery of systemically-active drug |
| JPH0538010Y2 (https=) * | 1987-03-17 | 1993-09-27 | ||
| DE3722775A1 (de) * | 1987-07-09 | 1989-01-19 | Lohmann Therapie Syst Lts | Transdermales therapeutisches system |
| US5474783A (en) * | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| US5236714A (en) * | 1988-11-01 | 1993-08-17 | Alza Corporation | Abusable substance dosage form having reduced abuse potential |
| US5176917A (en) * | 1989-03-15 | 1993-01-05 | Lts Lohmann | Transdermal system exhibiting graduated drug release and its use for the local or systemic administration of active substances |
| US5149538A (en) * | 1991-06-14 | 1992-09-22 | Warner-Lambert Company | Misuse-resistive transdermal opioid dosage form |
| US5756117A (en) * | 1992-04-08 | 1998-05-26 | International Medical Asscociates, Inc. | Multidose transdermal drug delivery system |
| CA2173855C (en) * | 1993-10-29 | 2007-06-26 | Mieczyslaw H. Mazurek | Pressure-sensitive adhesives having microstructured surfaces |
| US5494680A (en) * | 1993-12-08 | 1996-02-27 | Minnesota Mining And Manufacturing Company | Transdermal delivery device |
| WO1997004835A1 (de) * | 1995-07-28 | 1997-02-13 | Novartis Ag | Transdermales system |
| US5840327A (en) * | 1995-08-21 | 1998-11-24 | Alza Corporation | Transdermal drug delivery device having enhanced adhesion |
| US5985317A (en) * | 1996-09-06 | 1999-11-16 | Theratech, Inc. | Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents |
| US20020110585A1 (en) * | 1999-11-30 | 2002-08-15 | Godbey Kristin J. | Patch therapeutic agent delivery device having texturized backing |
| US20020119187A1 (en) * | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
| ATE364380T1 (de) * | 2001-03-16 | 2007-07-15 | Alza Corp | Transdermales pflaster zur verabreichung von fentanyl |
| SI2062573T1 (sl) * | 2001-05-01 | 2012-02-29 | Euro Celtique Sa | Proti zlorabi odporni transdermalni sistemi, ki vsebujejo opioid |
| TW200404581A (en) * | 2002-04-23 | 2004-04-01 | Alza Corp | Transdermal analgesic systems with reduced abuse potential |
| DK1530469T3 (da) * | 2002-08-20 | 2009-05-04 | Euro Celtique Sa | Transdermal dosisform omfattende et aktivt middel og et salt og fri baseform af en antagonist |
| US20040109886A1 (en) * | 2002-08-27 | 2004-06-10 | Larry Rigby | Methods and apparatus for transdermal delivery of abusable drugs with a deterrent agent |
| US20040191301A1 (en) * | 2003-03-27 | 2004-09-30 | Van Duren Albert Philip | Transdermal device having a phase change material |
| US7182955B2 (en) * | 2003-04-30 | 2007-02-27 | 3M Innovative Properties Company | Abuse-resistant transdermal dosage form |
| KR101159828B1 (ko) * | 2003-04-30 | 2012-07-04 | 퍼듀 퍼머 엘피 | 활성제 구성요소 및 활성제 층의 원위부에 억제제 구성요소를 포함하는 내변조성 경피제형 |
| DE102004038179A1 (de) * | 2004-08-06 | 2006-03-16 | Daimlerchrysler Ag | Verfahren zur Herstellung einer thermisch beschichteten Zylinderlauffläche mit einer Einfuhrfase |
-
2003
- 2003-12-23 US US10/744,966 patent/US20040219195A1/en active Granted
-
2004
- 2004-03-23 JP JP2006507485A patent/JP2006525315A/ja active Pending
- 2004-03-23 EP EP04760495A patent/EP1651196B1/en not_active Expired - Lifetime
- 2004-03-23 AU AU2004237579A patent/AU2004237579A1/en not_active Abandoned
- 2004-03-23 AT AT04760495T patent/ATE423551T1/de not_active IP Right Cessation
- 2004-03-23 CA CA002523709A patent/CA2523709A1/en not_active Abandoned
- 2004-03-23 ES ES04760495T patent/ES2322154T3/es not_active Expired - Lifetime
- 2004-03-23 DE DE602004019653T patent/DE602004019653D1/de not_active Expired - Lifetime
- 2004-03-23 WO PCT/US2004/008856 patent/WO2004098568A2/en not_active Ceased
-
2009
- 2009-11-19 US US12/621,595 patent/US20100068249A1/en not_active Abandoned
-
2010
- 2010-12-24 AU AU2010257440A patent/AU2010257440B2/en not_active Ceased
-
2012
- 2012-03-21 JP JP2012064165A patent/JP2012140453A/ja active Pending
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