JP2006523723A - 医薬的に活性な化合物を調節して導入する方法 - Google Patents

医薬的に活性な化合物を調節して導入する方法 Download PDF

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Publication number
JP2006523723A
JP2006523723A JP2006513123A JP2006513123A JP2006523723A JP 2006523723 A JP2006523723 A JP 2006523723A JP 2006513123 A JP2006513123 A JP 2006513123A JP 2006513123 A JP2006513123 A JP 2006513123A JP 2006523723 A JP2006523723 A JP 2006523723A
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acid
mammal
tilmicosin
active compound
pharmaceutically acceptable
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Japanese (ja)
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JP2006523723A5 (enExample
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ブイ．エス．エヌ． マーシー，イェラミリ
エイチ． スバ，ロバート
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アイデックス ラボラトリーズ，インコーポレイティド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2006513123A 2003-04-18 2004-04-15 医薬的に活性な化合物を調節して導入する方法 Pending JP2006523723A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/418,946 US6946137B2 (en) 2001-10-19 2003-04-18 Methods for the controlled delivery of pharmacologically active compounds
PCT/US2004/012030 WO2004091541A2 (en) 2003-04-18 2004-04-15 Methods for the controlled delivery of pharmacologically active compounds

Publications (2)

Publication Number Publication Date
JP2006523723A true JP2006523723A (ja) 2006-10-19
JP2006523723A5 JP2006523723A5 (enExample) 2007-05-31

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JP2006513123A Pending JP2006523723A (ja) 2003-04-18 2004-04-15 医薬的に活性な化合物を調節して導入する方法

Country Status (5)

Country Link
US (1) US6946137B2 (enExample)
EP (1) EP1617847A4 (enExample)
JP (1) JP2006523723A (enExample)
CA (1) CA2522009C (enExample)
WO (1) WO2004091541A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6887487B2 (en) * 2001-10-19 2005-05-03 Idexx Laboratories, Inc. Injectable compositions for the controlled delivery of pharmacologically active compound
JP2007509949A (ja) * 2003-10-29 2007-04-19 アイデックス ラボラトリーズ，インコーポレイティド 薬理学的に活性な化合物の塩
US7282487B2 (en) * 2004-10-28 2007-10-16 Idexx Laboratories Method for treating bacterial infections in horses or pigs with tilmicosin
EP1804771A2 (en) * 2004-10-28 2007-07-11 Idexx Laboratories, Inc. Compositions for controlled delivery of pharmaceutically active compounds
AU2006283040B2 (en) 2005-08-22 2011-08-25 The Johns Hopkins University Hedgehog pathway antagonists to treat disease
US7754679B2 (en) * 2005-11-16 2010-07-13 Idexx Laboratories, Inc. Pharmaceutical compositions for the administration of aptamers
US8114440B2 (en) * 2005-11-16 2012-02-14 Idexx Laboratories Inc. Pharmaceutical compositions for the administration of aptamers
US8828960B2 (en) * 2007-07-17 2014-09-09 Idexx Laboratories, Inc. Amino acid vitamin ester compositions for controlled delivery of pharmaceutically active compounds
USRE46397E1 (en) * 2007-11-07 2017-05-09 Svip5 Llc Slow release of organic salts of local anesthetics for pain relief
MX364800B (es) * 2014-02-18 2019-04-26 Univ Mexico Nac Autonoma Tilmicosina de accion prolongada mejorada y el uso de la misma en el tratamiento del complejo respiratorio bovino (crb) y en el periodo de la vaca seca.
CN108210936A (zh) * 2016-12-13 2018-06-29 河南后羿实业集团有限公司 一种替米考星包合物及其制备方法
CN113350297B (zh) * 2021-06-11 2022-11-04 河南金大众生物工程有限公司 一种替米考星干混悬剂及其制备方法
KR20230155155A (ko) * 2022-05-03 2023-11-10 녹십자수의약품 주식회사 마크로라이드 계열 항생제를 유효성분으로 포함하는 개과 동물의 호흡기 질환의 예방 또는 치료용 조성물

Citations (11)

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JPH01149732A (ja) * 1987-10-30 1989-06-12 Lilly Ind Ltd ソマトトロピン製剤
JPH02115118A (ja) * 1988-10-24 1990-04-27 Wakunaga Pharmaceut Co Ltd 注射剤
JPH04505762A (ja) * 1989-05-26 1992-10-08 アボツト・ラボラトリーズ クラリトロマイシンの注射用組成物
JPH08157391A (ja) * 1994-12-07 1996-06-18 Fujirebio Inc ナフトエ酸誘導体の吸収促進組成物
JPH08508032A (ja) * 1993-03-24 1996-08-27 ノーブルック ラボラトリーズ リミテッド タイロシンを含有する長期持続性動物薬
US5574020A (en) * 1989-09-28 1996-11-12 Eli Lilly And Company Tilmicosin formulation
JPH11171794A (ja) * 1997-12-04 1999-06-29 Shoji Awazu 動脈注射製剤
WO1999056725A1 (fr) * 1998-04-30 1999-11-11 Ucb, S.A. Compositions pharmaceutiques gelifiables
JP2001512487A (ja) * 1997-02-20 2001-08-21 マトリックス ファーマシューティカル，インコーポレイティド 抗細胞増殖剤のゲル送出ベヒクル
JP2001517613A (ja) * 1997-09-22 2001-10-09 バフォード バイオメディカル， インコーポレイテッド 薬物を含有する化合物の制御放出用の無機物−ポリマー複合体
JP2005511477A (ja) * 2001-03-19 2005-04-28 プラエシス ファーマシューティカルズ インコーポレーテッド 持続放出のための医薬調合物

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Publication number Priority date Publication date Assignee Title
JPH01149732A (ja) * 1987-10-30 1989-06-12 Lilly Ind Ltd ソマトトロピン製剤
JPH02115118A (ja) * 1988-10-24 1990-04-27 Wakunaga Pharmaceut Co Ltd 注射剤
JPH04505762A (ja) * 1989-05-26 1992-10-08 アボツト・ラボラトリーズ クラリトロマイシンの注射用組成物
US5574020A (en) * 1989-09-28 1996-11-12 Eli Lilly And Company Tilmicosin formulation
JPH08508032A (ja) * 1993-03-24 1996-08-27 ノーブルック ラボラトリーズ リミテッド タイロシンを含有する長期持続性動物薬
JPH08157391A (ja) * 1994-12-07 1996-06-18 Fujirebio Inc ナフトエ酸誘導体の吸収促進組成物
JP2001512487A (ja) * 1997-02-20 2001-08-21 マトリックス ファーマシューティカル，インコーポレイティド 抗細胞増殖剤のゲル送出ベヒクル
JP2001517613A (ja) * 1997-09-22 2001-10-09 バフォード バイオメディカル， インコーポレイテッド 薬物を含有する化合物の制御放出用の無機物−ポリマー複合体
JPH11171794A (ja) * 1997-12-04 1999-06-29 Shoji Awazu 動脈注射製剤
WO1999056725A1 (fr) * 1998-04-30 1999-11-11 Ucb, S.A. Compositions pharmaceutiques gelifiables
JP2005511477A (ja) * 2001-03-19 2005-04-28 プラエシス ファーマシューティカルズ インコーポレーテッド 持続放出のための医薬調合物

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JPN6009023824, Ｍ．Ｈ．Ｒａｇｈｉｂ ｅｔ ａｌ．, "Ｓｍａｌｌ−ａｎｉｍａｌ Ｓｔｕｄｉｅｓ ｏｆ Ｐｏｔｅｎｔｉａｌ Ｃｏｐｐｅｒ−ｃｏｎｔａｉｎｉｎｇ Ｉｎｊｅｃｔａｂｌｅｓ", Ｊ Ｃｏｎｔｒｏｌ Ｒｅｌｅａｓｅ．, 1989, Ｖｏｌ．９, ｐ．５７−６４ *

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Publication number Publication date
US6946137B2 (en) 2005-09-20
CA2522009A1 (en) 2004-10-28
EP1617847A2 (en) 2006-01-25
WO2004091541A3 (en) 2004-12-16
WO2004091541A2 (en) 2004-10-28
EP1617847A4 (en) 2011-08-10
CA2522009C (en) 2012-06-19
US20040023899A1 (en) 2004-02-05

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