JP2006523711A5 - - Google Patents

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Publication number
JP2006523711A5
JP2006523711A5 JP2006510118A JP2006510118A JP2006523711A5 JP 2006523711 A5 JP2006523711 A5 JP 2006523711A5 JP 2006510118 A JP2006510118 A JP 2006510118A JP 2006510118 A JP2006510118 A JP 2006510118A JP 2006523711 A5 JP2006523711 A5 JP 2006523711A5
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JP
Japan
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composition
seq
composition according
amino acid
acid sequence
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JP2006510118A
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English (en)
Japanese (ja)
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JP2006523711A (ja
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Priority claimed from PCT/US2004/011767 external-priority patent/WO2004093894A2/en
Publication of JP2006523711A publication Critical patent/JP2006523711A/ja
Publication of JP2006523711A5 publication Critical patent/JP2006523711A5/ja
Withdrawn legal-status Critical Current

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JP2006510118A 2003-04-17 2004-04-16 免疫調節因子としてのb7−h3の使用 Withdrawn JP2006523711A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46334203P 2003-04-17 2003-04-17
PCT/US2004/011767 WO2004093894A2 (en) 2003-04-17 2004-04-16 Use of b7-h3 as an immunoregulatory agent

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007095108A Division JP2007191489A (ja) 2003-04-17 2007-03-30 免疫調節因子としてのb7−h3の使用

Publications (2)

Publication Number Publication Date
JP2006523711A JP2006523711A (ja) 2006-10-19
JP2006523711A5 true JP2006523711A5 (enExample) 2007-05-24

Family

ID=33310770

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006510118A Withdrawn JP2006523711A (ja) 2003-04-17 2004-04-16 免疫調節因子としてのb7−h3の使用
JP2007095108A Withdrawn JP2007191489A (ja) 2003-04-17 2007-03-30 免疫調節因子としてのb7−h3の使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2007095108A Withdrawn JP2007191489A (ja) 2003-04-17 2007-03-30 免疫調節因子としてのb7−h3の使用

Country Status (14)

Country Link
US (1) US20050002935A1 (enExample)
EP (1) EP1620119A2 (enExample)
JP (2) JP2006523711A (enExample)
KR (1) KR20060017496A (enExample)
CN (1) CN1809370A (enExample)
AU (1) AU2004231748A1 (enExample)
BR (1) BRPI0409476A (enExample)
CA (1) CA2521847A1 (enExample)
CO (1) CO5700783A2 (enExample)
MX (1) MXPA05011050A (enExample)
NO (1) NO20054790L (enExample)
RU (1) RU2005135739A (enExample)
WO (1) WO2004093894A2 (enExample)
ZA (1) ZA200508367B (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2412377A1 (en) 2000-06-06 2001-12-13 Bristol-Myers Squibb Company B7-related nucleic acids and polypeptides and their uses for immunomodulation
US20030031675A1 (en) 2000-06-06 2003-02-13 Mikesell Glen E. B7-related nucleic acids and polypeptides useful for immunomodulation
AU2003292696A1 (en) 2002-12-26 2004-08-10 Takeda Pharmaceutical Company Limited Metastin derivative and use thereof
BRPI0512397A (pt) 2004-06-25 2008-03-04 Takeda Pharmaceutical composto,produto farmacêutico, métodos para suprimir a metástase de cáncer ou o crescimento do cáncer, para prevenir ou tratar uma doença ou condição, para controlar a função placentária, para melhorar a função gonadal, para induzir ou estimular a ovulação, para promover a secreção do hormÈnio gonadotrópico ou promover a secreção do hormÈnio sexual, para suprimir a secreção do hormÈnio gonadotrópico ou suprimir a secreção do hormÈnio sexual, para infra regular hormÈnio gonadrotópico ou hormÈnio sexual, e a proteìna ot7t175 humana, e para realçar a estabilidade no sangue, uso do composto, e, agente para suprimir a secreção do hormÈnio gonadotrópico ou um agente para suprimir a secreção do hormÈnio sexual
US8404643B2 (en) 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
AR058584A1 (es) 2005-12-22 2008-02-13 Takeda Pharmaceutical Derivados de metastina y uso de los mismos
JO3048B1 (ar) 2006-10-25 2016-09-05 Takeda Pharmaceuticals Co مشتقات متاستين واستخدامها
JP5601836B2 (ja) * 2006-11-08 2014-10-08 マクロジェニックス ウエスト, インコーポレイテッド Tes7およびtes7に結合する抗体
DK2542256T3 (da) 2010-03-04 2019-08-26 Macrogenics Inc Antistoffer reagerende med b7-h3, immunologisk aktive fragmenter deraf og anvendelser deraf
PH12012501751A1 (en) 2010-03-04 2012-11-12 Macrogenics Inc Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
ES2667568T3 (es) * 2011-04-25 2018-05-11 Daiichi Sankyo Company, Limited Anticuerpo anti-B7-H3
US9487587B2 (en) 2013-03-05 2016-11-08 Macrogenics, Inc. Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof
EP3104880B1 (en) 2014-02-14 2020-03-25 MacroGenics, Inc. Improved methods for the treatment of vascularizing cancers
CN108136010A (zh) 2015-10-08 2018-06-08 宏观基因有限公司 用于治疗癌症的联合疗法
TWI781098B (zh) 2016-04-15 2022-10-21 美商宏觀基因股份有限公司 新穎的b7-h3-結合分子、其抗體藥物綴合物及其使用方法
BR112019019111A2 (pt) * 2017-03-31 2020-05-05 Jiangsu Hengrui Medicine Co., Ltd. anticorpo de b7-h3, seu fragmento de ligação ao antígeno e seu uso médico
CN109097366A (zh) * 2017-06-21 2018-12-28 黄海东 突变的人2Ig-B7-H3蛋白编码基因、重组载体、其药物组合物及其应用
CN112239502B (zh) * 2019-07-18 2024-07-30 泰州复旦张江药业有限公司 一种抗b7-h3抗体及其制备方法、其偶联物和应用
US12312406B2 (en) 2018-11-09 2025-05-27 Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. Anti-B7-H3 antibody, preparation method therefor, conjugate and application thereof
JP7315703B2 (ja) * 2018-12-24 2023-07-26 ▲海▼▲東▼ 黄 組み換えヒト2Ig-B7-H3タンパク質コーディング遺伝子、組換えベクター及びそれを含む宿主細胞、並びに薬物組成物及びその応用
CN111454357B (zh) * 2019-08-14 2022-03-15 康诺亚生物医药科技(成都)有限公司 一种含有抗体的肿瘤治疗剂的开发和应用
CN111088227A (zh) * 2019-12-31 2020-05-01 广州航华生物医药科技有限公司 一种细胞分离培养液和t细胞分离培养的方法
KR20230145038A (ko) 2021-02-09 2023-10-17 메디링크 테라퓨틱스 (쑤저우) 컴퍼니, 리미티드 생물활성 물질 접합체, 이의 제조방법 및 이의 용도
CN113144181B (zh) * 2021-04-20 2022-07-19 徐州医科大学 一种靶向b7h3的dna疫苗、制备方法及应用
EP4480499A1 (en) 2022-02-16 2024-12-25 Medilink Therapeutics (Suzhou) Co., Ltd. Conjugate of antibody-eribulin or derivative thereof, intermediate thereof, preparation method therefor, pharmaceutical composition thereof and use thereof
JP2025516873A (ja) 2022-05-18 2025-05-30 ▲蘇▼州宜▲聯▼生物医▲薬▼有限公司 タンパク質分解剤クラスの生物学的活性化合物を含む抗体薬物複合体及びその調製方法並びに使用
CN120898001A (zh) * 2023-01-10 2025-11-04 上海仁又生基因技术有限公司 重组人2Ig-B7-H3蛋白编码基因、重组载体、宿主细胞、药物组合物及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2412377A1 (en) * 2000-06-06 2001-12-13 Bristol-Myers Squibb Company B7-related nucleic acids and polypeptides and their uses for immunomodulation
US6891030B2 (en) * 2000-07-27 2005-05-10 Mayo Foundation For Medical Education And Research T-cell immunoregulatory molecule
WO2003014293A2 (en) * 2001-08-02 2003-02-20 Eli Lilly And Company Novel polypeptide analogs and fusions and their methods of use

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