JP2006523711A5 - - Google Patents
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- JP2006523711A5 JP2006523711A5 JP2006510118A JP2006510118A JP2006523711A5 JP 2006523711 A5 JP2006523711 A5 JP 2006523711A5 JP 2006510118 A JP2006510118 A JP 2006510118A JP 2006510118 A JP2006510118 A JP 2006510118A JP 2006523711 A5 JP2006523711 A5 JP 2006523711A5
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- JP
- Japan
- Prior art keywords
- composition
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- composition according
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46334203P | 2003-04-17 | 2003-04-17 | |
| PCT/US2004/011767 WO2004093894A2 (en) | 2003-04-17 | 2004-04-16 | Use of b7-h3 as an immunoregulatory agent |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007095108A Division JP2007191489A (ja) | 2003-04-17 | 2007-03-30 | 免疫調節因子としてのb7−h3の使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006523711A JP2006523711A (ja) | 2006-10-19 |
| JP2006523711A5 true JP2006523711A5 (enExample) | 2007-05-24 |
Family
ID=33310770
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006510118A Withdrawn JP2006523711A (ja) | 2003-04-17 | 2004-04-16 | 免疫調節因子としてのb7−h3の使用 |
| JP2007095108A Withdrawn JP2007191489A (ja) | 2003-04-17 | 2007-03-30 | 免疫調節因子としてのb7−h3の使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007095108A Withdrawn JP2007191489A (ja) | 2003-04-17 | 2007-03-30 | 免疫調節因子としてのb7−h3の使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20050002935A1 (enExample) |
| EP (1) | EP1620119A2 (enExample) |
| JP (2) | JP2006523711A (enExample) |
| KR (1) | KR20060017496A (enExample) |
| CN (1) | CN1809370A (enExample) |
| AU (1) | AU2004231748A1 (enExample) |
| BR (1) | BRPI0409476A (enExample) |
| CA (1) | CA2521847A1 (enExample) |
| CO (1) | CO5700783A2 (enExample) |
| MX (1) | MXPA05011050A (enExample) |
| NO (1) | NO20054790L (enExample) |
| RU (1) | RU2005135739A (enExample) |
| WO (1) | WO2004093894A2 (enExample) |
| ZA (1) | ZA200508367B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2412377A1 (en) | 2000-06-06 | 2001-12-13 | Bristol-Myers Squibb Company | B7-related nucleic acids and polypeptides and their uses for immunomodulation |
| US20030031675A1 (en) | 2000-06-06 | 2003-02-13 | Mikesell Glen E. | B7-related nucleic acids and polypeptides useful for immunomodulation |
| AU2003292696A1 (en) | 2002-12-26 | 2004-08-10 | Takeda Pharmaceutical Company Limited | Metastin derivative and use thereof |
| BRPI0512397A (pt) | 2004-06-25 | 2008-03-04 | Takeda Pharmaceutical | composto,produto farmacêutico, métodos para suprimir a metástase de cáncer ou o crescimento do cáncer, para prevenir ou tratar uma doença ou condição, para controlar a função placentária, para melhorar a função gonadal, para induzir ou estimular a ovulação, para promover a secreção do hormÈnio gonadotrópico ou promover a secreção do hormÈnio sexual, para suprimir a secreção do hormÈnio gonadotrópico ou suprimir a secreção do hormÈnio sexual, para infra regular hormÈnio gonadrotópico ou hormÈnio sexual, e a proteìna ot7t175 humana, e para realçar a estabilidade no sangue, uso do composto, e, agente para suprimir a secreção do hormÈnio gonadotrópico ou um agente para suprimir a secreção do hormÈnio sexual |
| US8404643B2 (en) | 2005-12-22 | 2013-03-26 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
| AR058584A1 (es) | 2005-12-22 | 2008-02-13 | Takeda Pharmaceutical | Derivados de metastina y uso de los mismos |
| JO3048B1 (ar) | 2006-10-25 | 2016-09-05 | Takeda Pharmaceuticals Co | مشتقات متاستين واستخدامها |
| JP5601836B2 (ja) * | 2006-11-08 | 2014-10-08 | マクロジェニックス ウエスト, インコーポレイテッド | Tes7およびtes7に結合する抗体 |
| DK2542256T3 (da) | 2010-03-04 | 2019-08-26 | Macrogenics Inc | Antistoffer reagerende med b7-h3, immunologisk aktive fragmenter deraf og anvendelser deraf |
| PH12012501751A1 (en) | 2010-03-04 | 2012-11-12 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| ES2667568T3 (es) * | 2011-04-25 | 2018-05-11 | Daiichi Sankyo Company, Limited | Anticuerpo anti-B7-H3 |
| US9487587B2 (en) | 2013-03-05 | 2016-11-08 | Macrogenics, Inc. | Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof |
| EP3104880B1 (en) | 2014-02-14 | 2020-03-25 | MacroGenics, Inc. | Improved methods for the treatment of vascularizing cancers |
| CN108136010A (zh) | 2015-10-08 | 2018-06-08 | 宏观基因有限公司 | 用于治疗癌症的联合疗法 |
| TWI781098B (zh) | 2016-04-15 | 2022-10-21 | 美商宏觀基因股份有限公司 | 新穎的b7-h3-結合分子、其抗體藥物綴合物及其使用方法 |
| BR112019019111A2 (pt) * | 2017-03-31 | 2020-05-05 | Jiangsu Hengrui Medicine Co., Ltd. | anticorpo de b7-h3, seu fragmento de ligação ao antígeno e seu uso médico |
| CN109097366A (zh) * | 2017-06-21 | 2018-12-28 | 黄海东 | 突变的人2Ig-B7-H3蛋白编码基因、重组载体、其药物组合物及其应用 |
| CN112239502B (zh) * | 2019-07-18 | 2024-07-30 | 泰州复旦张江药业有限公司 | 一种抗b7-h3抗体及其制备方法、其偶联物和应用 |
| US12312406B2 (en) | 2018-11-09 | 2025-05-27 | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | Anti-B7-H3 antibody, preparation method therefor, conjugate and application thereof |
| JP7315703B2 (ja) * | 2018-12-24 | 2023-07-26 | ▲海▼▲東▼ 黄 | 組み換えヒト2Ig-B7-H3タンパク質コーディング遺伝子、組換えベクター及びそれを含む宿主細胞、並びに薬物組成物及びその応用 |
| CN111454357B (zh) * | 2019-08-14 | 2022-03-15 | 康诺亚生物医药科技(成都)有限公司 | 一种含有抗体的肿瘤治疗剂的开发和应用 |
| CN111088227A (zh) * | 2019-12-31 | 2020-05-01 | 广州航华生物医药科技有限公司 | 一种细胞分离培养液和t细胞分离培养的方法 |
| KR20230145038A (ko) | 2021-02-09 | 2023-10-17 | 메디링크 테라퓨틱스 (쑤저우) 컴퍼니, 리미티드 | 생물활성 물질 접합체, 이의 제조방법 및 이의 용도 |
| CN113144181B (zh) * | 2021-04-20 | 2022-07-19 | 徐州医科大学 | 一种靶向b7h3的dna疫苗、制备方法及应用 |
| EP4480499A1 (en) | 2022-02-16 | 2024-12-25 | Medilink Therapeutics (Suzhou) Co., Ltd. | Conjugate of antibody-eribulin or derivative thereof, intermediate thereof, preparation method therefor, pharmaceutical composition thereof and use thereof |
| JP2025516873A (ja) | 2022-05-18 | 2025-05-30 | ▲蘇▼州宜▲聯▼生物医▲薬▼有限公司 | タンパク質分解剤クラスの生物学的活性化合物を含む抗体薬物複合体及びその調製方法並びに使用 |
| CN120898001A (zh) * | 2023-01-10 | 2025-11-04 | 上海仁又生基因技术有限公司 | 重组人2Ig-B7-H3蛋白编码基因、重组载体、宿主细胞、药物组合物及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2412377A1 (en) * | 2000-06-06 | 2001-12-13 | Bristol-Myers Squibb Company | B7-related nucleic acids and polypeptides and their uses for immunomodulation |
| US6891030B2 (en) * | 2000-07-27 | 2005-05-10 | Mayo Foundation For Medical Education And Research | T-cell immunoregulatory molecule |
| WO2003014293A2 (en) * | 2001-08-02 | 2003-02-20 | Eli Lilly And Company | Novel polypeptide analogs and fusions and their methods of use |
-
2004
- 2004-04-15 US US10/824,481 patent/US20050002935A1/en not_active Abandoned
- 2004-04-16 BR BRPI0409476-0A patent/BRPI0409476A/pt not_active IP Right Cessation
- 2004-04-16 MX MXPA05011050A patent/MXPA05011050A/es not_active Application Discontinuation
- 2004-04-16 CA CA002521847A patent/CA2521847A1/en not_active Abandoned
- 2004-04-16 EP EP04750222A patent/EP1620119A2/en not_active Withdrawn
- 2004-04-16 AU AU2004231748A patent/AU2004231748A1/en not_active Abandoned
- 2004-04-16 KR KR1020057019786A patent/KR20060017496A/ko not_active Withdrawn
- 2004-04-16 WO PCT/US2004/011767 patent/WO2004093894A2/en not_active Ceased
- 2004-04-16 JP JP2006510118A patent/JP2006523711A/ja not_active Withdrawn
- 2004-04-16 RU RU2005135739/13A patent/RU2005135739A/ru not_active Application Discontinuation
- 2004-04-16 CN CNA2004800170492A patent/CN1809370A/zh not_active Withdrawn
-
2005
- 2005-10-14 ZA ZA200508367A patent/ZA200508367B/en unknown
- 2005-10-18 NO NO20054790A patent/NO20054790L/no not_active Application Discontinuation
- 2005-11-17 CO CO05116756A patent/CO5700783A2/es not_active Application Discontinuation
-
2007
- 2007-03-30 JP JP2007095108A patent/JP2007191489A/ja not_active Withdrawn
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