AU2004231748A1 - Use of B7-H3 as an immunoregulatory agent - Google Patents
Use of B7-H3 as an immunoregulatory agent Download PDFInfo
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- AU2004231748A1 AU2004231748A1 AU2004231748A AU2004231748A AU2004231748A1 AU 2004231748 A1 AU2004231748 A1 AU 2004231748A1 AU 2004231748 A AU2004231748 A AU 2004231748A AU 2004231748 A AU2004231748 A AU 2004231748A AU 2004231748 A1 AU2004231748 A1 AU 2004231748A1
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- A61K38/482—Serine endopeptidases (3.4.21)
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
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- C07—ORGANIC CHEMISTRY
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- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/51—B7 molecules, e.g. CD80, CD86, CD28 (ligand), CD152 (ligand)
Landscapes
- Health & Medical Sciences (AREA)
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- Immunology (AREA)
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- Public Health (AREA)
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- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
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- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
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- Microbiology (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46334203P | 2003-04-17 | 2003-04-17 | |
| US60/463,342 | 2003-04-17 | ||
| PCT/US2004/011767 WO2004093894A2 (en) | 2003-04-17 | 2004-04-16 | Use of b7-h3 as an immunoregulatory agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2004231748A1 true AU2004231748A1 (en) | 2004-11-04 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2004231748A Abandoned AU2004231748A1 (en) | 2003-04-17 | 2004-04-16 | Use of B7-H3 as an immunoregulatory agent |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20050002935A1 (enExample) |
| EP (1) | EP1620119A2 (enExample) |
| JP (2) | JP2006523711A (enExample) |
| KR (1) | KR20060017496A (enExample) |
| CN (1) | CN1809370A (enExample) |
| AU (1) | AU2004231748A1 (enExample) |
| BR (1) | BRPI0409476A (enExample) |
| CA (1) | CA2521847A1 (enExample) |
| CO (1) | CO5700783A2 (enExample) |
| MX (1) | MXPA05011050A (enExample) |
| NO (1) | NO20054790L (enExample) |
| RU (1) | RU2005135739A (enExample) |
| WO (1) | WO2004093894A2 (enExample) |
| ZA (1) | ZA200508367B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001094413A2 (en) | 2000-06-06 | 2001-12-13 | Bristol-Myers Squibb Company | B7-related nucleic acids and polypeptides and their uses for immunomodulation |
| US20030031675A1 (en) | 2000-06-06 | 2003-02-13 | Mikesell Glen E. | B7-related nucleic acids and polypeptides useful for immunomodulation |
| WO2004063221A1 (ja) | 2002-12-26 | 2004-07-29 | Takeda Pharmaceutical Company Limited | メタスチン誘導体およびその用途 |
| PE20091567A1 (es) | 2004-06-25 | 2009-11-03 | Takeda Pharmaceutical | Derivados de metastina en el tratamiento del cancer |
| US8404643B2 (en) | 2005-12-22 | 2013-03-26 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
| TWI386417B (zh) | 2005-12-22 | 2013-02-21 | Takeda Pharmaceutical | 轉移抑素衍生物及其用途 |
| TWI404726B (zh) | 2006-10-25 | 2013-08-11 | Takeda Pharmaceutical | 腫瘤轉移抑制素衍生物及其用途 |
| CA2668800A1 (en) * | 2006-11-08 | 2008-06-05 | Macrogenics West, Inc. | Tes7 and antibodies that bind thereto |
| PH12012501751A1 (en) | 2010-03-04 | 2012-11-12 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| PH12018501083A1 (en) | 2010-03-04 | 2019-02-18 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| EP2703486B1 (en) * | 2011-04-25 | 2018-03-07 | Daiichi Sankyo Company, Limited | Anti-b7-h3 antibody |
| US9487587B2 (en) | 2013-03-05 | 2016-11-08 | Macrogenics, Inc. | Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof |
| US10100115B2 (en) | 2014-02-14 | 2018-10-16 | Macrogenics, Inc. | Methods for the treatment of vascularizing cancers |
| BR112018006817A2 (pt) | 2015-10-08 | 2018-10-23 | Macrogenics Inc | método de tratamento do câncer |
| EP3442574A4 (en) | 2016-04-15 | 2019-12-11 | MacroGenics, Inc. | Novel B7-H3 binding MOLECULES, ANTIBODY-ACTIVE CONJUGATES AND METHOD OF USE THEREOF |
| BR112019019111A2 (pt) * | 2017-03-31 | 2020-05-05 | Jiangsu Hengrui Medicine Co | anticorpo de b7-h3, seu fragmento de ligação ao antígeno e seu uso médico |
| CN109097366A (zh) * | 2017-06-21 | 2018-12-28 | 黄海东 | 突变的人2Ig-B7-H3蛋白编码基因、重组载体、其药物组合物及其应用 |
| US12312406B2 (en) | 2018-11-09 | 2025-05-27 | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | Anti-B7-H3 antibody, preparation method therefor, conjugate and application thereof |
| SG11202106952UA (en) * | 2018-12-24 | 2021-08-30 | Haidong Huang | Recombinant human 2ig-b7-h3 protein coding gene, recombinant vector, host cell comprising the same, pharmaceutical composition and use thereof |
| CN118878681A (zh) * | 2019-07-18 | 2024-11-01 | 泰州复旦张江药业有限公司 | 一种抗b7-h3抗体及其制备方法、其偶联物和应用 |
| CN111454357B (zh) * | 2019-08-14 | 2022-03-15 | 康诺亚生物医药科技（成都）有限公司 | 一种含有抗体的肿瘤治疗剂的开发和应用 |
| CN111088227A (zh) * | 2019-12-31 | 2020-05-01 | 广州航华生物医药科技有限公司 | 一种细胞分离培养液和t细胞分离培养的方法 |
| CN120093941A (zh) | 2021-02-09 | 2025-06-06 | 苏州宜联生物医药有限公司 | 生物活性物偶联物及其制备方法和用途 |
| CN113144181B (zh) * | 2021-04-20 | 2022-07-19 | 徐州医科大学 | 一种靶向b7h3的dna疫苗、制备方法及应用 |
| US20250144229A1 (en) | 2022-02-16 | 2025-05-08 | Medlink Therapeutics (Suzhou) Co., Ltd. | Conjugate of antibody-eribulin or derivative thereof, intermediate thereof, preparation method therefor, pharmaceutical composition thereof and use thereof |
| US20250325688A1 (en) | 2022-05-18 | 2025-10-23 | Medilink Therapeutics (Suzhou) Co., Ltd. | Antibody-drug conjugate containing protein degradation agent bioactive compound, method for preparing same, and use thereof |
| CN120898001A (zh) * | 2023-01-10 | 2025-11-04 | 上海仁又生基因技术有限公司 | 重组人2Ig-B7-H3蛋白编码基因、重组载体、宿主细胞、药物组合物及其应用 |
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| WO2001094413A2 (en) * | 2000-06-06 | 2001-12-13 | Bristol-Myers Squibb Company | B7-related nucleic acids and polypeptides and their uses for immunomodulation |
| AU2001283507A1 (en) * | 2000-07-27 | 2002-02-13 | Mayo Foundation For Medical Education And Research | B7-h3 and b7-h4, novel immunoregulatory molecules |
| AU2002347761A1 (en) * | 2001-08-02 | 2003-02-24 | Eli Lilly And Company | Novel polypeptide analogs and fusions and their methods of use |
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2004
- 2004-04-15 US US10/824,481 patent/US20050002935A1/en not_active Abandoned
- 2004-04-16 WO PCT/US2004/011767 patent/WO2004093894A2/en not_active Ceased
- 2004-04-16 MX MXPA05011050A patent/MXPA05011050A/es not_active Application Discontinuation
- 2004-04-16 JP JP2006510118A patent/JP2006523711A/ja not_active Withdrawn
- 2004-04-16 CA CA002521847A patent/CA2521847A1/en not_active Abandoned
- 2004-04-16 BR BRPI0409476-0A patent/BRPI0409476A/pt not_active IP Right Cessation
- 2004-04-16 KR KR1020057019786A patent/KR20060017496A/ko not_active Withdrawn
- 2004-04-16 AU AU2004231748A patent/AU2004231748A1/en not_active Abandoned
- 2004-04-16 RU RU2005135739/13A patent/RU2005135739A/ru not_active Application Discontinuation
- 2004-04-16 CN CNA2004800170492A patent/CN1809370A/zh not_active Withdrawn
- 2004-04-16 EP EP04750222A patent/EP1620119A2/en not_active Withdrawn
-
2005
- 2005-10-14 ZA ZA200508367A patent/ZA200508367B/en unknown
- 2005-10-18 NO NO20054790A patent/NO20054790L/no not_active Application Discontinuation
- 2005-11-17 CO CO05116756A patent/CO5700783A2/es not_active Application Discontinuation
-
2007
- 2007-03-30 JP JP2007095108A patent/JP2007191489A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| NO20054790L (no) | 2005-11-16 |
| CN1809370A (zh) | 2006-07-26 |
| ZA200508367B (en) | 2007-04-25 |
| JP2006523711A (ja) | 2006-10-19 |
| WO2004093894A2 (en) | 2004-11-04 |
| WO2004093894A3 (en) | 2005-03-24 |
| RU2005135739A (ru) | 2006-03-20 |
| JP2007191489A (ja) | 2007-08-02 |
| MXPA05011050A (es) | 2006-03-17 |
| CO5700783A2 (es) | 2006-11-30 |
| KR20060017496A (ko) | 2006-02-23 |
| NO20054790D0 (no) | 2005-10-18 |
| BRPI0409476A (pt) | 2006-05-02 |
| WO2004093894A8 (en) | 2005-05-19 |
| EP1620119A2 (en) | 2006-02-01 |
| US20050002935A1 (en) | 2005-01-06 |
| CA2521847A1 (en) | 2004-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |