JP2006523669A - Ｎｉｍａ調節タンパク質（ｐｉｎ１）を阻害するための、リン酸／硫酸エステル化合物および医薬組成物 - Google Patents

Ｎｉｍａ調節タンパク質（ｐｉｎ１）を阻害するための、リン酸／硫酸エステル化合物および医薬組成物 Download PDF

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JP2006523669A
JP2006523669A JP2006506287A JP2006506287A JP2006523669A JP 2006523669 A JP2006523669 A JP 2006523669A JP 2006506287 A JP2006506287 A JP 2006506287A JP 2006506287 A JP2006506287 A JP 2006506287A JP 2006523669 A JP2006523669 A JP 2006523669A
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グオ チュアングキシング
フェッロニャルカ ダゴスティーノ エレアノー
ドング リミング
ホウ シンジュン
アンソニー マルゴシアク ステファン
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ファイザー・インク
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2006506287A 2003-03-10 2004-02-23 Ｎｉｍａ調節タンパク質（ｐｉｎ１）を阻害するための、リン酸／硫酸エステル化合物および医薬組成物 Pending JP2006523669A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45316303P 2003-03-10 2003-03-10
PCT/IB2004/000574 WO2004087720A1 (en) 2003-03-10 2004-02-23 Phosphate/sulfate ester compounds and pharmaceutical compositions for inhibiting protein interacting nima (pin1)

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JP2006523669A true JP2006523669A (ja) 2006-10-19

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JP2006506287A Pending JP2006523669A (ja) 2003-03-10 2004-02-23 Ｎｉｍａ調節タンパク質（ｐｉｎ１）を阻害するための、リン酸／硫酸エステル化合物および医薬組成物

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EP (1) EP1603926A1 (de)
JP (1) JP2006523669A (de)
BR (1) BRPI0408477A (de)
CA (1) CA2517281A1 (de)
MX (1) MXPA05009241A (de)
WO (1) WO2004087720A1 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018101329A1 (ja) * 2016-11-29 2018-06-07 国立大学法人広島大学 新規エステル体化合物並びにそれを用いたＰｉｎ１阻害剤、炎症性疾患治療剤及び大腸癌治療剤
JP2020505411A (ja) * 2017-01-31 2020-02-20 ギリアード サイエンシーズ， インコーポレイテッド テノホビルアラフェナミドの結晶形態
WO2022270628A1 (ja) * 2021-06-25 2022-12-29 国立大学法人 大分大学 Ｒｓウイルス感染症の処置および／または予防用医薬としてのヘテロシクロアルキル置換ポリヘテロアゾール誘導体

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WO2005080406A2 (en) * 2003-12-19 2005-09-01 Jerini Ag Compounds for the inhibition of undesired cell proliferation and use thereof
US7504413B2 (en) 2004-05-06 2009-03-17 Cytokinetics, Inc. N-(4-(imidazo[1,2A]pyridin-YL)phenethyl)benzamide inhibitors of the mitotic kinesin CENP-E for treating certain cellular proliferation diseases
US7618981B2 (en) * 2004-05-06 2009-11-17 Cytokinetics, Inc. Imidazopyridinyl-benzamide anti-cancer agents
US7795448B2 (en) 2004-05-06 2010-09-14 Cytokinetics, Incorporated Imidazoyl-benzamide anti-cancer agents
WO2006040646A1 (en) * 2004-10-14 2006-04-20 Pfizer, Inc. Benzimidazole or indole amides as inhibitors of pin1
EP2845588A1 (de) * 2013-09-09 2015-03-11 Centre National de la Recherche Scientifique (C.N.R.S.) PIN1-Hemmer zur Verwendung bei der Vorbeugung und/oder Behandlung von Theileriose sowie zugehörige Anwendungen
MA40770B1 (fr) 2014-10-03 2021-11-30 Sanofi Sa Dérivés d'imidazoles pentacyclic fusionnés
WO2017063754A1 (en) 2015-10-12 2017-04-20 Polyphor Ag Conformationally constrained macrocyclic compounds as pin1 modulators
WO2017063756A1 (en) * 2015-10-12 2017-04-20 Polyphor Ag Conformationally constrained macrocyclic compounds as pin1 modulators
WO2017063755A1 (en) 2015-10-12 2017-04-20 Polyphor Ag Conformationally constrained macrocyclic compounds
WO2017063757A1 (en) 2015-10-12 2017-04-20 Polyphor Ag Conformationally constrained macrocyclic compounds
CN109195969B (zh) 2016-04-01 2021-12-21 Ucb生物制药私人有限公司 作为tnf活性调节剂的稠合五环咪唑衍生物
JP6968090B2 (ja) 2016-04-01 2021-11-17 ユーシービー バイオファルマ エスアールエル Ｔｎｆ活性のモジュレーターとしての縮合五環式イミダゾール誘導体
CN109219608B (zh) 2016-04-01 2021-12-21 Ucb生物制药私人有限公司 作为tnf活性调节剂的稠合五环咪唑衍生物
WO2017167995A1 (en) 2016-04-01 2017-10-05 Ucb Biopharma Sprl Fused hexacyclic imidazole derivatives as modulators of tnf activity
CN110461842A (zh) 2017-03-15 2019-11-15 Ucb生物制药私人有限公司 作为tnf活性调节剂的稠合五环咪唑衍生物
WO2019031471A1 (ja) 2017-08-07 2019-02-14 国立大学法人広島大学 脂肪性肝疾患の治療剤及び肥満症の治療剤
JP7229482B2 (ja) 2017-08-07 2023-02-28 国立大学法人広島大学 新規アミド系化合物、並びにそれを用いたＰｉｎ１阻害剤、炎症性疾患の治療剤及び癌の治療剤
US20200383967A1 (en) 2017-08-07 2020-12-10 Hiroshima University Novel Anthranilic Acid-Based Compound, and Pin1 Inhibitor, Therapeutic Agent for Inflammatory Diseases and Therapeutic Agent for Cancer That Use the Same
WO2021182457A1 (ja) 2020-03-12 2021-09-16 国立大学法人広島大学 新規３，５－ジアミノ安息香酸系化合物、並びにそれを用いたＰｉｎ１阻害剤及び炎症性疾患の治療剤
WO2022032179A1 (en) * 2020-08-07 2022-02-10 The Regents Of The University Of California Pin1 inhibitors and uses thereof
JP2022080079A (ja) 2020-11-17 2022-05-27 国立大学法人広島大学 Ｃｏｖｉｄ－１９の治療剤又は予防剤

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WO2018101329A1 (ja) * 2016-11-29 2018-06-07 国立大学法人広島大学 新規エステル体化合物並びにそれを用いたＰｉｎ１阻害剤、炎症性疾患治療剤及び大腸癌治療剤
JPWO2018101329A1 (ja) * 2016-11-29 2019-10-31 国立大学法人広島大学 新規エステル体化合物並びにそれを用いたＰｉｎ１阻害剤、炎症性疾患治療剤及び大腸癌治療剤
US11203565B2 (en) 2016-11-29 2021-12-21 Hiroshima University Ester compound and PIN1 inhibitor, inflammatory disease therapeutic, and colon cancer therapeutic in which said ester compound is used
JP7048054B2 (ja) 2016-11-29 2022-04-05 国立大学法人広島大学 新規エステル体化合物並びにそれを用いたＰｉｎ１阻害剤、炎症性疾患治療剤及び大腸癌治療剤
JP2020505411A (ja) * 2017-01-31 2020-02-20 ギリアード サイエンシーズ， インコーポレイテッド テノホビルアラフェナミドの結晶形態
WO2022270628A1 (ja) * 2021-06-25 2022-12-29 国立大学法人 大分大学 Ｒｓウイルス感染症の処置および／または予防用医薬としてのヘテロシクロアルキル置換ポリヘテロアゾール誘導体

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