JP2006521824A5 - - Google Patents

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Publication number
JP2006521824A5
JP2006521824A5 JP2006509580A JP2006509580A JP2006521824A5 JP 2006521824 A5 JP2006521824 A5 JP 2006521824A5 JP 2006509580 A JP2006509580 A JP 2006509580A JP 2006509580 A JP2006509580 A JP 2006509580A JP 2006521824 A5 JP2006521824 A5 JP 2006521824A5
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JP
Japan
Prior art keywords
nucleic acid
polymerase inhibitor
polymerase
acid sequence
inhibitor according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006509580A
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English (en)
Japanese (ja)
Other versions
JP2006521824A (ja
JP4567673B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/010029 external-priority patent/WO2004090153A2/en
Publication of JP2006521824A publication Critical patent/JP2006521824A/ja
Publication of JP2006521824A5 publication Critical patent/JP2006521824A5/ja
Application granted granted Critical
Publication of JP4567673B2 publication Critical patent/JP4567673B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2006509580A 2003-04-01 2004-04-01 ポリメラーゼ阻害剤およびその使用方法 Expired - Lifetime JP4567673B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45967203P 2003-04-01 2003-04-01
PCT/US2004/010029 WO2004090153A2 (en) 2003-04-01 2004-04-01 Polymerase inhibitor and method of using same

Publications (3)

Publication Number Publication Date
JP2006521824A JP2006521824A (ja) 2006-09-28
JP2006521824A5 true JP2006521824A5 (enExample) 2010-07-15
JP4567673B2 JP4567673B2 (ja) 2010-10-20

Family

ID=33159672

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006509580A Expired - Lifetime JP4567673B2 (ja) 2003-04-01 2004-04-01 ポリメラーゼ阻害剤およびその使用方法

Country Status (6)

Country Link
US (2) US7820808B2 (enExample)
EP (1) EP1615942B1 (enExample)
JP (1) JP4567673B2 (enExample)
AU (1) AU2004227353B2 (enExample)
CA (1) CA2521127C (enExample)
WO (1) WO2004090153A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6830902B1 (en) * 1999-07-02 2004-12-14 Invitrogen Corporation Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis
BRPI0516619B1 (pt) * 2004-10-18 2016-02-10 Univ Brandeis reagentes, kit de reagentes e conjunto de oligonucleotídeos para realização de uma amplificação por reação em cadeia de polimerase
EP2458011B1 (en) * 2005-10-03 2013-07-24 Life Technologies Corporation Compositions, methods, and kits for amplifying nucleic acids
US8012694B2 (en) * 2006-09-14 2011-09-06 Immutopics, Inc. Assay for the detection of phosphorylated PTH
US10865431B1 (en) * 2008-06-17 2020-12-15 Steven A Benner Polymerase incorporation of non-standard nucleotides
CA2688174C (en) * 2008-12-19 2018-08-07 F. Hoffmann-La Roche Ag Dry composition of reaction compounds with stabilized polymerase
EP2703501A1 (en) * 2009-03-12 2014-03-05 Brandeis University Reagents and Methods for PCR
CN102791877A (zh) * 2009-11-06 2012-11-21 酶学有限公司 使用双链核酸复合物与耐热聚合酶用于合成脱氧核糖核苷酸链的组合物和方法
CN109477111B (zh) 2016-06-07 2023-12-15 塞弗德公司 热稳定聚合酶抑制剂组合物和方法
GB201611469D0 (en) 2016-06-30 2016-08-17 Lumiradx Tech Ltd Improvements in or relating to nucleic acid amplification processes
GB2569965A (en) 2018-01-04 2019-07-10 Lumiradx Uk Ltd Improvements in or relating to amplification of nucleic acids
WO2020010124A2 (en) * 2018-07-02 2020-01-09 Swift Biosciences, Inc. Temperature controlled dna polymerase inhibitors
CN115135664A (zh) * 2020-06-22 2022-09-30 苏州新海生物科技股份有限公司 一种核酸配体及其应用

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US5470974A (en) 1985-03-15 1995-11-28 Neu-Gene Development Group Uncharged polynucleotide-binding polymers
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4996143A (en) 1985-12-23 1991-02-26 Syngene, Inc. Fluorescent stokes shift probes for polynucleotide hybridization
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
IL86164A0 (en) * 1987-04-28 1988-11-15 Tamir Biotechnology Ltd Improved dna probes
JPH0344560Y2 (enExample) 1987-08-24 1991-09-19
CA1339352C (en) 1987-09-22 1997-08-26 Harry P. Rappaport Artificial dna base pair analogues
US6054270A (en) 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
US6444798B1 (en) 1988-06-06 2002-09-03 Steven Albert Benner Chimeras of sulfur-linked oligonucleotide analogs and DNA and RNA
GB8827160D0 (en) 1988-11-21 1988-12-29 Apothekernes Lab Detection & quantitative determination of rna & dna
GB8902689D0 (en) 1989-02-07 1989-03-30 Ici Plc Assay method
US5856092A (en) 1989-02-13 1999-01-05 Geneco Pty Ltd Detection of a nucleic acid sequence or a change therein
GB8920097D0 (en) 1989-09-06 1989-10-18 Ici Plc Amplification processes
US6007984A (en) 1989-11-01 1999-12-28 Zeneca Limited Detection of DNA/RNA by fluorescence polarization
US5412088A (en) 1989-11-20 1995-05-02 Rutgers, The State University 6-O-substituted guanosine derivatives
US5763173A (en) 1990-06-11 1998-06-09 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand inhibitors to DNA polymerases
US5693502A (en) 1990-06-11 1997-12-02 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand inhibitors to DNA polymerases
US5874557A (en) 1990-06-11 1999-02-23 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand inhibitors to DNA polymerases
US5552541A (en) 1990-06-20 1996-09-03 Beckman Instruments, Inc. Haptenic probes for detecting capture polynucleotides
US5177064A (en) 1990-07-13 1993-01-05 University Of Florida Targeted drug delivery via phosphonate derivatives
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US6140496A (en) 1990-10-09 2000-10-31 Benner; Steven Albert Precursors for deoxyribonucleotides containing non-standard nucleosides
US6037120A (en) 1995-10-12 2000-03-14 Benner; Steven Albert Recognition of oligonucleotides containing non-standard base pairs
US5432272A (en) 1990-10-09 1995-07-11 Benner; Steven A. Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases
US5965364A (en) 1990-10-09 1999-10-12 Benner; Steven Albert Method for selecting functional deoxyribonucleotide derivatives
JP3228738B2 (ja) 1990-12-21 2001-11-12 エフ，ホフマン ― ラ ロシュ アーゲー Ｈｌａ ｄｑベータｄｎａタイピング
DE4129653A1 (de) 1991-09-06 1993-03-11 Boehringer Mannheim Gmbh Verfahren zum nachweis aehnlicher nukleinsaeuren
US5846717A (en) 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
US5958784A (en) 1992-03-25 1999-09-28 Benner; Steven Albert Predicting folded structures of proteins
AU3933393A (en) 1993-03-17 1994-10-11 City Of Hope Nucleic acid sequences having single stranded ends
US6156501A (en) 1993-10-26 2000-12-05 Affymetrix, Inc. Arrays of modified nucleic acid probes and methods of use
EP0754240B1 (en) 1994-02-07 2003-08-20 Beckman Coulter, Inc. Ligase/polymerase-mediated genetic bit analysis of single nucleotide polymorphisms and its use in genetic analysis
US5681702A (en) 1994-08-30 1997-10-28 Chiron Corporation Reduction of nonspecific hybridization by using novel base-pairing schemes
US5604097A (en) 1994-10-13 1997-02-18 Spectragen, Inc. Methods for sorting polynucleotides using oligonucleotide tags
US5565340A (en) 1995-01-27 1996-10-15 Clontech Laboratories, Inc. Method for suppressing DNA fragment amplification during PCR
GB9507238D0 (en) 1995-04-07 1995-05-31 Isis Innovation Detecting dna sequence variations
US6183967B1 (en) 1995-06-07 2001-02-06 Nexstar Pharmaceuticals Nucleic acid ligand inhibitors to DNA polymerases
JP4335975B2 (ja) 1995-06-07 2009-09-30 ギリード・サイエンシズ・インコーポレーテッド Ｄｎａポリメラーゼに対する結合・阻害核酸リガンド
US5736330A (en) 1995-10-11 1998-04-07 Luminex Corporation Method and compositions for flow cytometric determination of DNA sequences
US5705621A (en) 1995-11-17 1998-01-06 Isis Pharmaceuticals, Inc. Oligomeric phosphite, phosphodiester, Phosphorothioate and phosphorodithioate compounds and intermediates for preparing same
AU2320597A (en) 1996-03-19 1997-10-10 Molecular Tool, Inc. Method for determining the nucleotide sequence of a polynucleotide
US5780233A (en) 1996-06-06 1998-07-14 Wisconsin Alumni Research Foundation Artificial mismatch hybridization
US6124092A (en) 1996-10-04 2000-09-26 The Perkin-Elmer Corporation Multiplex polynucleotide capture methods and compositions
US6482590B1 (en) 1996-12-20 2002-11-19 Aventis Behring Gmbh Method for polynucleotide amplification
US7101672B2 (en) 1998-05-05 2006-09-05 Third Wave Technologies, Inc. Target-dependent reactions using structure-bridging oligonucleotides
JP4185185B2 (ja) 1997-05-08 2008-11-26 征夫 軽部 部分二重鎖ｄｎａを利用したｄｎａの検出方法
US5928869A (en) 1997-05-30 1999-07-27 Becton, Dickinson And Company Detection of nucleic acids by fluorescence quenching
PT1040202E (pt) 1997-10-28 2009-03-26 Los Alamos Nat Security Llc Determinação da identidade de polimorfismos de adn utilizando citometria de fluxo
GB9725197D0 (en) 1997-11-29 1998-01-28 Secr Defence Detection system
AU3996299A (en) 1998-05-14 1999-11-29 Luminex Corporation Diode laser based measurement apparatus
DE69940430D1 (de) 1998-06-24 2009-04-02 Illumina Inc Dekodierung von matrixartig-angeordneten Sensoren durch Mikropartikel
US6200757B1 (en) 1999-01-19 2001-03-13 Dade Behring Inc. Method for controlling the extension of an oligonucleotide
US6274353B1 (en) 1999-09-22 2001-08-14 Genecopoeia, Inc. Method and compositions for improved polynucleotide synthesis
US6528254B1 (en) 1999-10-29 2003-03-04 Stratagene Methods for detection of a target nucleic acid sequence
US6509157B1 (en) 1999-11-05 2003-01-21 Roche Molecular Systems, Inc 3 blocked nucleic acid amplification primers
AU2001229576A1 (en) 2000-01-15 2001-07-24 Genelabs Technologies, Inc. Nucleic acid binding site assay and selection method
WO2001075139A1 (en) 2000-04-03 2001-10-11 Biolink Partners, Inc. Reversible chemical modification of nucleic acids and improved method for nucleic acid hybridization
WO2001090417A2 (en) 2000-05-19 2001-11-29 Eragen Biosciences, Inc. Materials and methods for detection of nucleic acids
AU2002213175B2 (en) 2000-10-14 2007-09-13 Luminex Corporation Solid support assay systems and methods utilizing non-standard bases
AU2002351198B2 (en) 2001-11-28 2008-08-14 Bio-Rad Laboratories, Inc. Methods of using improved polymerases
US20030194705A1 (en) 2002-03-01 2003-10-16 Schroth Gary P. Methods of using unnatural nucleobases for decoding
US7282333B2 (en) 2003-10-20 2007-10-16 Promega Corporation Methods and compositions for nucleic acid analysis

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