JP2006521111A - 血管形成及び腫瘍増殖阻害用ポリペプチド化合物及びその応用 - Google Patents

血管形成及び腫瘍増殖阻害用ポリペプチド化合物及びその応用 Download PDF

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JP2006521111A
JP2006521111A JP2006507160A JP2006507160A JP2006521111A JP 2006521111 A JP2006521111 A JP 2006521111A JP 2006507160 A JP2006507160 A JP 2006507160A JP 2006507160 A JP2006507160 A JP 2006507160A JP 2006521111 A JP2006521111 A JP 2006521111A
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ephb4
polypeptide
ephrin
protein
soluble
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JP2006521111A5 (https=
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クラスノペロフ，バレリー
ゾズリア，セルゲイ
ケルテズ，ナタリー
レディ，ラマチャンドラ
ギル，パルカシュ
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バスジーン セラピューティクス， インコーポレイテッド
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/315—Phosphorothioates

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JP2006507160A 2003-03-12 2004-03-12 血管形成及び腫瘍増殖阻害用ポリペプチド化合物及びその応用 Pending JP2006521111A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45430003P 2003-03-12 2003-03-12
US45443203P 2003-03-12 2003-03-12
PCT/US2004/007755 WO2004080425A2 (en) 2003-03-12 2004-03-12 Polypeptide compounds for inhibiting angiogenesis and tumor growth

Related Child Applications (1)

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JP2011157200A Division JP2011256179A (ja) 2003-03-12 2011-07-15 血管形成及び腫瘍増殖阻害用ポリペプチド化合物及びその応用

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JP2006521111A true JP2006521111A (ja) 2006-09-21
JP2006521111A5 JP2006521111A5 (https=) 2007-05-24

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JP2006507160A Pending JP2006521111A (ja) 2003-03-12 2004-03-12 血管形成及び腫瘍増殖阻害用ポリペプチド化合物及びその応用
JP2006507095A Expired - Fee Related JP4762889B2 (ja) 2003-03-12 2004-03-12 血管形成及び腫瘍成長を阻止するための核酸化合物
JP2011157200A Pending JP2011256179A (ja) 2003-03-12 2011-07-15 血管形成及び腫瘍増殖阻害用ポリペプチド化合物及びその応用

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JP2006507095A Expired - Fee Related JP4762889B2 (ja) 2003-03-12 2004-03-12 血管形成及び腫瘍成長を阻止するための核酸化合物
JP2011157200A Pending JP2011256179A (ja) 2003-03-12 2011-07-15 血管形成及び腫瘍増殖阻害用ポリペプチド化合物及びその応用

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US (5) US7585967B2 (https=)
EP (2) EP1606305A4 (https=)
JP (3) JP2006521111A (https=)
AU (3) AU2004220525B2 (https=)
CA (2) CA2518912A1 (https=)
WO (2) WO2004080425A2 (https=)

Cited By (2)

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JP2011256179A (ja) * 2003-03-12 2011-12-22 Vasgene Therapeutics Inc 血管形成及び腫瘍増殖阻害用ポリペプチド化合物及びその応用
JP2015071566A (ja) * 2013-10-03 2015-04-16 住友ベークライト株式会社 Ｆｇｆ４遺伝子増幅腫瘍の医薬組成物

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