JP2006512894A5 - - Google Patents

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Publication number
JP2006512894A5
JP2006512894A5 JP2004511349A JP2004511349A JP2006512894A5 JP 2006512894 A5 JP2006512894 A5 JP 2006512894A5 JP 2004511349 A JP2004511349 A JP 2004511349A JP 2004511349 A JP2004511349 A JP 2004511349A JP 2006512894 A5 JP2006512894 A5 JP 2006512894A5
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JP
Japan
Prior art keywords
fusion protein
pharmaceutical composition
homodimeric
nucleic acid
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2004511349A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006512894A (ja
JP4722480B2 (ja
Filing date
Publication date
Priority claimed from EP02012742A external-priority patent/EP1369128A1/en
Application filed filed Critical
Publication of JP2006512894A publication Critical patent/JP2006512894A/ja
Publication of JP2006512894A5 publication Critical patent/JP2006512894A5/ja
Application granted granted Critical
Publication of JP4722480B2 publication Critical patent/JP4722480B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2004511349A 2002-06-07 2003-06-05 糖タンパク質viドメインを含むイムノアドヘシン Expired - Lifetime JP4722480B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02012742.9 2002-06-07
EP02012742A EP1369128A1 (en) 2002-06-07 2002-06-07 Inhibitors of glycoprotein VI and their therapeutic use
PCT/EP2003/005929 WO2003104282A2 (en) 2002-06-07 2003-06-05 Immunoadhesin comprising a glycoprotein vi domain

Publications (3)

Publication Number Publication Date
JP2006512894A JP2006512894A (ja) 2006-04-20
JP2006512894A5 true JP2006512894A5 (enExample) 2006-07-06
JP4722480B2 JP4722480B2 (ja) 2011-07-13

Family

ID=29433140

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004511349A Expired - Lifetime JP4722480B2 (ja) 2002-06-07 2003-06-05 糖タンパク質viドメインを含むイムノアドヘシン

Country Status (13)

Country Link
US (1) US7514543B2 (enExample)
EP (4) EP1369128A1 (enExample)
JP (1) JP4722480B2 (enExample)
CN (1) CN1668721B (enExample)
AT (1) ATE346095T1 (enExample)
AU (2) AU2003236704B2 (enExample)
CA (1) CA2488630C (enExample)
DE (1) DE60309865T2 (enExample)
DK (1) DK1860118T3 (enExample)
ES (2) ES2276078T3 (enExample)
SI (1) SI1511770T1 (enExample)
WO (2) WO2003103662A2 (enExample)
ZA (1) ZA200409776B (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7531178B2 (en) 2002-06-07 2009-05-12 Trigen Gmbh Immunoadhesin comprising a glycoprotein VI domain
GB0511590D0 (en) * 2005-06-07 2005-07-13 Procorde Gmbh Anti-thrombotic agents
WO2006061650A2 (en) * 2004-12-10 2006-06-15 Trigen Gmbh Methods, products and uses involving platelets and/or the vasculature
US20070071744A1 (en) 2002-06-07 2007-03-29 Gotz Munch Agents which bind to epitopes of glycoprotein VI
EP1369128A1 (en) 2002-06-07 2003-12-10 Procorde GmbH Inhibitors of glycoprotein VI and their therapeutic use
RU2407752C2 (ru) 2004-04-29 2010-12-27 Оцука Фармасьютикал Ко., Лтд. Антитела к гликопротеину vi и способы продуцирования и использования этих антител
US7645592B2 (en) 2004-04-29 2010-01-12 Otsuka Pharmaceutical Co., Ltd. Glycoprotein VI antibodies and methods of use thereof
ES2381557T3 (es) 2004-08-03 2012-05-29 Innate Pharma Métodos terapéuticos y de diagnóstico y composiciones para determinar 4IG-B7-H3 y su receptor homólogo en las células NK
FR2884831B1 (fr) * 2005-04-22 2007-08-10 Merck Sante Soc Par Actions Si Methode de criblage de composes inhibiteurs de la mtp
JP5224707B2 (ja) * 2005-04-28 2013-07-03 持田製薬株式会社 抗血小板膜糖蛋白質viモノクローナル抗体
CA2606450A1 (en) * 2005-04-28 2006-11-09 Mochida Pharmaceutical Co., Ltd. Anti-platelet membrane glycoprotein vi monoclonal antibody
WO2006117910A1 (ja) 2005-04-28 2006-11-09 Mochida Pharmaceutical Co., Ltd. 抗血小板膜糖蛋白質ⅵモノクローナル抗体
KR20080078675A (ko) * 2005-12-22 2008-08-27 시오노기 앤드 컴파니, 리미티드 급성 관상동맥 증후군의 예후 예측 방법
AU2008319336A1 (en) * 2007-10-31 2009-05-07 Otsuka Pharmaceutical Co., Ltd. Uses of a glycoprotein VI (GPVI) inhibitor
EP2352815B1 (en) * 2008-12-04 2016-02-10 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for producing platelets
DK2429574T3 (da) 2009-05-15 2015-06-22 Univ Health Network Sammensætninger og fremgangsmåder til behandling af hæmatologiske cancere der targeterer sirp-cd47-interaktionen
EP2397495A1 (en) * 2010-06-21 2011-12-21 Sanofi Novel antagonist antibodies and their Fab fragments against GPVI and uses thereof
EP2336188A1 (en) * 2009-12-18 2011-06-22 Sanofi-Aventis Novel antagonist antibodies and their Fab fragments against GPVI and uses thereof
JP5843783B2 (ja) * 2009-12-18 2016-01-13 サノフイ GPVIに対する新規アンタゴニスト抗体および該抗体のFabフラグメントならびにこれらの使用
EP2377888A1 (en) * 2010-04-07 2011-10-19 Corimmun GmbH Fusion protein
ME03550B (me) 2012-12-17 2020-07-20 Trillium Therapeutics Inc Lečenje cd47+ obolelih ćelija sa sirp alfa-fc fuzijama
CN104871005B (zh) * 2012-12-20 2016-07-06 藤森工业株式会社 血小板凝集能力的综合评价方法
EP3424957A1 (en) 2017-07-03 2019-01-09 advanceCOR GmbH Fusion protein
CN110964119A (zh) * 2019-12-05 2020-04-07 沣潮医药科技(上海)有限公司 抗疟二聚体免疫粘附素、药物组合物和用途
WO2021158878A1 (en) * 2020-02-06 2021-08-12 Boehringer Ingelheim Animal Health USA Inc. Polypeptides useful for detecting anti-rhabdovirus antibodies

Family Cites Families (23)

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Publication number Priority date Publication date Assignee Title
US5156840A (en) * 1982-03-09 1992-10-20 Cytogen Corporation Amine-containing porphyrin derivatives
ZA887365B (en) 1987-10-02 1990-05-30 Genentech Inc Adheson variants
NZ226414A (en) 1987-10-02 1992-07-28 Genentech Inc Cd4 peptide adhesion variants and their preparation and use
US6406697B1 (en) * 1989-02-23 2002-06-18 Genentech, Inc. Hybrid immunoglobulins
US5116964A (en) * 1989-02-23 1992-05-26 Genentech, Inc. Hybrid immunoglobulins
US5525491A (en) * 1991-02-27 1996-06-11 Creative Biomolecules, Inc. Serine-rich peptide linkers
GB9806806D0 (en) 1998-03-30 1998-05-27 Univ Cambridge Tech Peptides and uses thereof
GB9809951D0 (en) 1998-05-08 1998-07-08 Univ Cambridge Tech Binding molecules
GB9810999D0 (en) * 1998-05-21 1998-07-22 Goken Joop Materials and methods relating to the expression of genes
DK1177289T3 (da) 1999-05-07 2008-08-11 Sanofi Aventis Deutschland Rekombinant blodpladecollagenreceptor glycopotein VI og dets farmaceutiske anvendelse
US20040001826A1 (en) 1999-06-30 2004-01-01 Millennium Pharmaceuticals, Inc. Glycoprotein VI and uses thereof
US6245527B1 (en) * 1999-06-30 2001-06-12 Millennium Pharmaceuticals, Inc. Nucleic acid molecules encoding glycoprotein VI and recombinant uses thereof
US7291714B1 (en) * 1999-06-30 2007-11-06 Millennium Pharmaceuticals, Inc. Glycoprotein VI and uses thereof
AU7097400A (en) * 1999-09-01 2001-03-26 Otsuka Pharmaceutical Co., Ltd. Platelet membrane glycoprotein vi (gpvi) dna and protein sequences, and uses thereof
EP1224942A1 (en) 2001-01-23 2002-07-24 Bernhard Dr. Nieswandt Use of JAQ1 (monoclonal antibody anti GPVI) as a medicament for the protection against thrombotic diseases
PT2070939E (pt) 2001-05-25 2014-06-09 Univ Duke Moduladores de agentes farmacológicos
WO2003008454A2 (en) 2001-07-18 2003-01-30 Merck Patent Gmbh Glycoprotein vi fusion proteins
GB0130543D0 (en) 2001-12-20 2002-02-06 Univ Cambridge Tech Human antibodies and their use
GB0130832D0 (en) 2001-12-22 2002-02-06 Univ Reading Modulation of the activity of the platelet endothelial cell adhesion molecule-1 (pecam-1)
GB0211750D0 (en) 2002-05-22 2002-07-03 Ouwehand Willem Abnormal blood conditions
EP1538165A1 (en) 2003-12-03 2005-06-08 Procorde GmbH Inhibitors of glycoprotein VI based on monoclonal antibody hgp 5c4
EP1369128A1 (en) 2002-06-07 2003-12-10 Procorde GmbH Inhibitors of glycoprotein VI and their therapeutic use
US7531178B2 (en) * 2002-06-07 2009-05-12 Trigen Gmbh Immunoadhesin comprising a glycoprotein VI domain

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