JP2006512894A5 - - Google Patents

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Publication number
JP2006512894A5
JP2006512894A5 JP2004511349A JP2004511349A JP2006512894A5 JP 2006512894 A5 JP2006512894 A5 JP 2006512894A5 JP 2004511349 A JP2004511349 A JP 2004511349A JP 2004511349 A JP2004511349 A JP 2004511349A JP 2006512894 A5 JP2006512894 A5 JP 2006512894A5
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JP
Japan
Prior art keywords
fusion protein
pharmaceutical composition
homodimeric
nucleic acid
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2004511349A
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English (en)
Japanese (ja)
Other versions
JP2006512894A (ja
JP4722480B2 (ja
Filing date
Publication date
Priority claimed from EP02012742A external-priority patent/EP1369128A1/en
Application filed filed Critical
Publication of JP2006512894A publication Critical patent/JP2006512894A/ja
Publication of JP2006512894A5 publication Critical patent/JP2006512894A5/ja
Application granted granted Critical
Publication of JP4722480B2 publication Critical patent/JP4722480B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2004511349A 2002-06-07 2003-06-05 糖タンパク質viドメインを含むイムノアドヘシン Expired - Lifetime JP4722480B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02012742A EP1369128A1 (en) 2002-06-07 2002-06-07 Inhibitors of glycoprotein VI and their therapeutic use
EP02012742.9 2002-06-07
PCT/EP2003/005929 WO2003104282A2 (en) 2002-06-07 2003-06-05 Immunoadhesin comprising a glycoprotein vi domain

Publications (3)

Publication Number Publication Date
JP2006512894A JP2006512894A (ja) 2006-04-20
JP2006512894A5 true JP2006512894A5 (enExample) 2006-07-06
JP4722480B2 JP4722480B2 (ja) 2011-07-13

Family

ID=29433140

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004511349A Expired - Lifetime JP4722480B2 (ja) 2002-06-07 2003-06-05 糖タンパク質viドメインを含むイムノアドヘシン

Country Status (13)

Country Link
US (1) US7514543B2 (enExample)
EP (4) EP1369128A1 (enExample)
JP (1) JP4722480B2 (enExample)
CN (1) CN1668721B (enExample)
AT (1) ATE346095T1 (enExample)
AU (2) AU2003236704B2 (enExample)
CA (1) CA2488630C (enExample)
DE (1) DE60309865T2 (enExample)
DK (1) DK1860118T3 (enExample)
ES (2) ES2276078T3 (enExample)
SI (1) SI1511770T1 (enExample)
WO (2) WO2003103662A2 (enExample)
ZA (1) ZA200409776B (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070071744A1 (en) 2002-06-07 2007-03-29 Gotz Munch Agents which bind to epitopes of glycoprotein VI
WO2006061650A2 (en) * 2004-12-10 2006-06-15 Trigen Gmbh Methods, products and uses involving platelets and/or the vasculature
EP1369128A1 (en) 2002-06-07 2003-12-10 Procorde GmbH Inhibitors of glycoprotein VI and their therapeutic use
US7531178B2 (en) 2002-06-07 2009-05-12 Trigen Gmbh Immunoadhesin comprising a glycoprotein VI domain
GB0511590D0 (en) * 2005-06-07 2005-07-13 Procorde Gmbh Anti-thrombotic agents
EP1745076B1 (en) 2004-04-29 2012-06-13 Otsuka Pharmaceutical Co., Ltd. Antibodies specific for glycoprotein vi and methods of producing these antibodies
US7645592B2 (en) 2004-04-29 2010-01-12 Otsuka Pharmaceutical Co., Ltd. Glycoprotein VI antibodies and methods of use thereof
DK2412728T3 (en) 2004-08-03 2015-04-07 Innate Pharma Therapeutic compositions for cancer, that target 4Ig-B7-H3
FR2884831B1 (fr) * 2005-04-22 2007-08-10 Merck Sante Soc Par Actions Si Methode de criblage de composes inhibiteurs de la mtp
WO2006117910A1 (ja) 2005-04-28 2006-11-09 Mochida Pharmaceutical Co., Ltd. 抗血小板膜糖蛋白質ⅵモノクローナル抗体
JP5224707B2 (ja) * 2005-04-28 2013-07-03 持田製薬株式会社 抗血小板膜糖蛋白質viモノクローナル抗体
EP1876240B1 (en) * 2005-04-28 2012-08-22 Mochida Pharmaceutical Co., Ltd. Anti-human platelet membrane glycoprotein vi monoclonal antibody
US20110045504A1 (en) * 2005-12-22 2011-02-24 Noriaki Kume Prognostic Prediction Method for Acute Coronary Syndrome
CN101874107A (zh) * 2007-10-31 2010-10-27 大塚制药株式会社 糖蛋白ⅵ(gpvi)抑制剂的用途
ES2569610T3 (es) * 2008-12-04 2016-05-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Método para producir plaquetas
PL2429574T3 (pl) * 2009-05-15 2015-12-31 Univ Health Network Kompozycje i sposoby leczenia nowotworów hematologicznych celujące w oddziaływanie SIRP-CD47
EP2397495A1 (en) * 2010-06-21 2011-12-21 Sanofi Novel antagonist antibodies and their Fab fragments against GPVI and uses thereof
EP2336188A1 (en) * 2009-12-18 2011-06-22 Sanofi-Aventis Novel antagonist antibodies and their Fab fragments against GPVI and uses thereof
MA33930B1 (fr) * 2009-12-18 2013-01-02 Sanofi Sa Nouveaux anticorps antagonistes contre gpvi et leurs fragments fab et utilisations de ceux-ci
EP2377888A1 (en) * 2010-04-07 2011-10-19 Corimmun GmbH Fusion protein
JP6335189B2 (ja) 2012-12-17 2018-05-30 トリリアム・セラピューティクス・インコーポレイテッドTrillium Therapeutics Inc. SIRPアルファ−Fc融合体でのCD47+疾患細胞の治療
CA2895693C (en) * 2012-12-20 2017-02-28 Fujimori Kogyo Co., Ltd. Method for comprehensive assessment of platelet aggregation
EP3424957A1 (en) 2017-07-03 2019-01-09 advanceCOR GmbH Fusion protein
CN110964119A (zh) * 2019-12-05 2020-04-07 沣潮医药科技(上海)有限公司 抗疟二聚体免疫粘附素、药物组合物和用途
JP2023513135A (ja) * 2020-02-06 2023-03-30 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー 抗ラブドウイルス抗体を検出するのに有用なポリペプチド

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US5156840A (en) * 1982-03-09 1992-10-20 Cytogen Corporation Amine-containing porphyrin derivatives
ZA887365B (en) 1987-10-02 1990-05-30 Genentech Inc Adheson variants
PT88641B (pt) 1987-10-02 1993-04-30 Genentech Inc Metodo para a preparacao de uma variante de adesao
US5116964A (en) 1989-02-23 1992-05-26 Genentech, Inc. Hybrid immunoglobulins
US6406697B1 (en) 1989-02-23 2002-06-18 Genentech, Inc. Hybrid immunoglobulins
US5525491A (en) * 1991-02-27 1996-06-11 Creative Biomolecules, Inc. Serine-rich peptide linkers
GB9806806D0 (en) 1998-03-30 1998-05-27 Univ Cambridge Tech Peptides and uses thereof
GB9809951D0 (en) 1998-05-08 1998-07-08 Univ Cambridge Tech Binding molecules
GB9810999D0 (en) * 1998-05-21 1998-07-22 Goken Joop Materials and methods relating to the expression of genes
HK1045714B (zh) 1999-05-07 2006-09-22 萨诺费-阿文蒂斯德国有限公司 重组血小板胶原受体糖蛋白vi及其药用
US7291714B1 (en) * 1999-06-30 2007-11-06 Millennium Pharmaceuticals, Inc. Glycoprotein VI and uses thereof
US20040001826A1 (en) 1999-06-30 2004-01-01 Millennium Pharmaceuticals, Inc. Glycoprotein VI and uses thereof
US6245527B1 (en) 1999-06-30 2001-06-12 Millennium Pharmaceuticals, Inc. Nucleic acid molecules encoding glycoprotein VI and recombinant uses thereof
WO2001016321A1 (en) 1999-09-01 2001-03-08 Otsuka Pharmaceutical Co., Ltd. Platelet membrane glycoprotein vi (gpvi) dna and protein sequences, and uses thereof
EP1224942A1 (en) 2001-01-23 2002-07-24 Bernhard Dr. Nieswandt Use of JAQ1 (monoclonal antibody anti GPVI) as a medicament for the protection against thrombotic diseases
PT1401853E (pt) 2001-05-25 2010-12-07 Univ Duke Modulador de oligonucleotídeos
WO2003008454A2 (en) 2001-07-18 2003-01-30 Merck Patent Gmbh Glycoprotein vi fusion proteins
GB0130543D0 (en) 2001-12-20 2002-02-06 Univ Cambridge Tech Human antibodies and their use
GB0130832D0 (en) 2001-12-22 2002-02-06 Univ Reading Modulation of the activity of the platelet endothelial cell adhesion molecule-1 (pecam-1)
GB0211750D0 (en) 2002-05-22 2002-07-03 Ouwehand Willem Abnormal blood conditions
EP1369128A1 (en) 2002-06-07 2003-12-10 Procorde GmbH Inhibitors of glycoprotein VI and their therapeutic use
US7531178B2 (en) 2002-06-07 2009-05-12 Trigen Gmbh Immunoadhesin comprising a glycoprotein VI domain
EP1538165A1 (en) 2003-12-03 2005-06-08 Procorde GmbH Inhibitors of glycoprotein VI based on monoclonal antibody hgp 5c4

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