JP2006296429A5 - - Google Patents

Info

Publication number

JP2006296429A5

JP2006296429A5 JP2006123920A JP2006123920A JP2006296429A5 JP 2006296429 A5 JP2006296429 A5 JP 2006296429A5 JP 2006123920 A JP2006123920 A JP 2006123920A JP 2006123920 A JP2006123920 A JP 2006123920A JP 2006296429 A5 JP2006296429 A5 JP 2006296429A5

Authority

JP

Japan

Prior art keywords

polypeptide

amino acid

acid sequence

seq

gene

Prior art date

2006-04-27

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 229920001184 polypeptide Polymers 0.000 claims 41
• 108090000765 processed proteins & peptides Proteins 0.000 claims 41
• 102000004196 processed proteins & peptides Human genes 0.000 claims 41
• 108090000623 proteins and genes Proteins 0.000 claims 19
• 125000003275 alpha amino acid group Chemical group 0.000 claims 18
• 150000001413 amino acids Chemical class 0.000 claims 12
• 230000033115 angiogenesis Effects 0.000 claims 8
• 230000002401 inhibitory effect Effects 0.000 claims 8
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 6
• 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 4
• 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 4
• 239000008194 pharmaceutical composition Substances 0.000 claims 4
• VEEGZPWAAPPXRB-BJMVGYQFSA-N (3e)-3-(1h-imidazol-5-ylmethylidene)-1h-indol-2-one Chemical compound O=C1NC2=CC=CC=C2\C1=C/C1=CN=CN1 VEEGZPWAAPPXRB-BJMVGYQFSA-N 0.000 claims 2
• 108020005187 Oligonucleotide Probes Proteins 0.000 claims 2
• 108020004511 Recombinant DNA Proteins 0.000 claims 2
• 229940121369 angiogenesis inhibitor Drugs 0.000 claims 2
• 239000004037 angiogenesis inhibitor Substances 0.000 claims 2
• 239000002773 nucleotide Substances 0.000 claims 2
• 125000003729 nucleotide group Chemical group 0.000 claims 2
• 239000002751 oligonucleotide probe Substances 0.000 claims 2
• 238000009007 Diagnostic Kit Methods 0.000 claims 1
• 108091034117 Oligonucleotide Proteins 0.000 claims 1
• 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
• 210000000628 antibody-producing cell Anatomy 0.000 claims 1
• 239000000074 antisense oligonucleotide Substances 0.000 claims 1
• 238000012230 antisense oligonucleotides Methods 0.000 claims 1
• 210000004027 cell Anatomy 0.000 claims 1
• 239000003153 chemical reaction reagent Substances 0.000 claims 1
• 238000012258 culturing Methods 0.000 claims 1
• 238000001514 detection method Methods 0.000 claims 1
• 238000001415 gene therapy Methods 0.000 claims 1
• 210000004408 hybridoma Anatomy 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 201000000050 myeloid neoplasm Diseases 0.000 claims 1
• 108020004707 nucleic acids Proteins 0.000 claims 1
• 102000039446 nucleic acids Human genes 0.000 claims 1
• 150000007523 nucleic acids Chemical class 0.000 claims 1