JP2002502589A5 - - Google Patents
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- Publication number
- JP2002502589A5 JP2002502589A5 JP2000530528A JP2000530528A JP2002502589A5 JP 2002502589 A5 JP2002502589 A5 JP 2002502589A5 JP 2000530528 A JP2000530528 A JP 2000530528A JP 2000530528 A JP2000530528 A JP 2000530528A JP 2002502589 A5 JP2002502589 A5 JP 2002502589A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- polynucleotide
- nucleic acid
- encoded
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920001184 polypeptide Polymers 0.000 description 28
- 102000004196 processed proteins & peptides Human genes 0.000 description 28
- 108090000765 processed proteins & peptides Proteins 0.000 description 28
- 102000040430 polynucleotide Human genes 0.000 description 20
- 108091033319 polynucleotide Proteins 0.000 description 20
- 239000002157 polynucleotide Substances 0.000 description 20
- 238000000034 method Methods 0.000 description 12
- 102000039446 nucleic acids Human genes 0.000 description 10
- 108020004707 nucleic acids Proteins 0.000 description 10
- 150000007523 nucleic acids Chemical class 0.000 description 10
- 239000012634 fragment Substances 0.000 description 9
- 239000002773 nucleotide Substances 0.000 description 9
- 125000003729 nucleotide group Chemical group 0.000 description 9
- 239000002299 complementary DNA Substances 0.000 description 8
- 108090000623 proteins and genes Proteins 0.000 description 5
- 102000004169 proteins and genes Human genes 0.000 description 4
- 230000037430 deletion Effects 0.000 description 3
- 238000012217 deletion Methods 0.000 description 3
- 238000004166 bioassay Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 239000006228 supernatant Substances 0.000 description 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7414198P | 1998-02-09 | 1998-02-09 | |
| US7415798P | 1998-02-09 | 1998-02-09 | |
| US7434198P | 1998-02-09 | 1998-02-09 | |
| US7411898P | 1998-02-09 | 1998-02-09 | |
| US7403798P | 1998-02-09 | 1998-02-09 | |
| US60/074,141 | 1998-02-09 | ||
| US60/074,118 | 1998-02-09 | ||
| US60/074,341 | 1998-02-09 | ||
| US60/074,037 | 1998-02-09 | ||
| US60/074,157 | 1998-02-09 | ||
| PCT/US1999/002293 WO1999040100A1 (en) | 1998-02-09 | 1999-02-04 | 45 human secreted proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002502589A JP2002502589A (ja) | 2002-01-29 |
| JP2002502589A5 true JP2002502589A5 (enExample) | 2006-03-09 |
Family
ID=27535993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000530528A Pending JP2002502589A (ja) | 1998-02-09 | 1999-02-04 | ４５個のヒト分泌タンパク質 |
Country Status (6)
| Country | Link |
|---|---|
| US (8) | US6569992B1 (enExample) |
| EP (1) | EP1053245A4 (enExample) |
| JP (1) | JP2002502589A (enExample) |
| AU (1) | AU2577799A (enExample) |
| CA (1) | CA2320625A1 (enExample) |
| WO (1) | WO1999040100A1 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999040100A1 (en) | 1998-02-09 | 1999-08-12 | Human Genome Sciences, Inc. | 45 human secreted proteins |
| US20030083461A1 (en) | 1997-06-16 | 2003-05-01 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US8088386B2 (en) | 1998-03-20 | 2012-01-03 | Genentech, Inc. | Treatment of complement-associated disorders |
| US8007798B2 (en) | 1997-11-21 | 2011-08-30 | Genentech, Inc. | Treatment of complement-associated disorders |
| US7419663B2 (en) | 1998-03-20 | 2008-09-02 | Genentech, Inc. | Treatment of complement-associated disorders |
| US7192589B2 (en) * | 1998-09-16 | 2007-03-20 | Genentech, Inc. | Treatment of inflammatory disorders with STIgMA immunoadhesins |
| NZ528697A (en) * | 1998-03-20 | 2005-02-25 | Genentech Inc | Novel PRO362 polypeptides and nucleic acids encoding same with homology to A33 antigen and HCAR membrane bound protein |
| WO1999055733A1 (en) * | 1998-04-24 | 1999-11-04 | Smithkline Beecham Corporation | Cloning of a novel 7tm receptor axor-2 |
| US7538086B2 (en) * | 1998-09-01 | 2009-05-26 | Genentech, Inc. | PRO1303 polypeptides |
| EP1135492A1 (en) * | 1998-11-25 | 2001-09-26 | Millennium Pharmaceuticals, Inc. | 12216 receptor, a g-protein coupled receptor |
| US7026449B2 (en) * | 1999-01-05 | 2006-04-11 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US8410248B2 (en) | 1999-03-12 | 2013-04-02 | Human Genome Sciences Inc. | HWBAO62 polypeptides |
| EP1208196B1 (en) | 1999-08-03 | 2006-10-18 | Millennium Pharmaceuticals, Inc. | 15571, a novel gpcr-like molecule of the secretin-like family and uses thereof |
| CA2388008A1 (en) * | 1999-11-05 | 2001-05-17 | Human Genome Sciences, Inc. | 29 human secreted proteins |
| AU1916101A (en) * | 1999-11-12 | 2001-06-06 | Human Genome Sciences, Inc. | 19 human secreted proteins |
| EP1228092A4 (en) * | 1999-11-12 | 2003-11-12 | Human Genome Sciences Inc | 24 HUMAN SECRETED PROTEINS |
| AU2001247283A1 (en) * | 2000-03-06 | 2001-09-17 | Lexicon Genetics Incorporated | Human transporter proteins and polynucleotides encoding the same |
| WO2002026982A2 (en) * | 2000-09-29 | 2002-04-04 | Incyte Genomics, Inc. | Secreted human proteins |
| WO2002092804A1 (en) * | 2001-05-15 | 2002-11-21 | Biovitrum Ab | Metalloprotease m8 polynucleotides and polypeptides and screening methods |
| US8546541B2 (en) | 2002-06-20 | 2013-10-01 | Washington University | Compositions and methods for modulating lymphocyte activity |
| EP1539218A4 (en) * | 2002-06-20 | 2007-08-22 | Univ California | COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY |
| EP1560593B1 (en) | 2002-10-25 | 2016-04-20 | Genentech, Inc. | Novel composition and methods for the treatment of immune related diseases |
| US20040248257A1 (en) * | 2003-04-30 | 2004-12-09 | The Scripps Research Institute | SPEX compositions and methods of use |
| US20050186577A1 (en) | 2004-02-20 | 2005-08-25 | Yixin Wang | Breast cancer prognostics |
| US8188232B1 (en) | 2004-11-15 | 2012-05-29 | Washington University In St. Louis | Compositions and methods for modulating lymphocyte activity |
| ES2551202T5 (es) | 2005-11-04 | 2018-11-30 | Genentech, Inc. | Uso de inhibidores de la vía del complemento para tratar enfermedades oculares |
| US20090325944A1 (en) * | 2006-04-12 | 2009-12-31 | Suzanne Walker Kahne | Methods and Compositions for Modulating Glycosylation |
| US7776573B2 (en) | 2006-06-01 | 2010-08-17 | Genentech, Inc. | Crystal structure of CRIg and C3b:CRIg complex |
| CN106084054A (zh) | 2006-11-02 | 2016-11-09 | 健泰科生物技术公司 | 人源化的抗‑d因子抗体 |
| AR066660A1 (es) | 2007-05-23 | 2009-09-02 | Genentech Inc | Prevencion y tratamiento de condiciones del ojo asociadas con su complemento |
| WO2008156676A1 (en) | 2007-06-15 | 2008-12-24 | President And Fellows Of Harvard College | Methods and compositions for detecting and modulating o-glycosylation |
| CR20170001A (es) | 2008-04-28 | 2017-08-10 | Genentech Inc | Anticuerpos anti factor d humanizados |
| LT2280996T (lt) | 2008-05-06 | 2016-12-12 | Genentech, Inc. | Subrendusio giminingumo crig variantai |
| US8957075B2 (en) | 2009-06-01 | 2015-02-17 | President And Fellows Of Harvard College | O-GlcNAc transferase inhibitors and uses thereof |
| US8303952B2 (en) | 2009-06-08 | 2012-11-06 | Washington University | Methods for inducing in vivo tolerance |
| AU2012327878A1 (en) | 2011-10-28 | 2014-05-29 | Patrys Limited | PAT-LM1 epitopes and methods for using same |
| CR20160132A (es) | 2013-08-12 | 2016-08-25 | Genentech Inc | Composiciones y método para tratar condiciones asociadas con el complemento |
| SG11201608868PA (en) | 2014-05-01 | 2016-11-29 | Genentech Inc | Anti-factor d antibody variants and uses thereof |
| TW201713690A (zh) | 2015-08-07 | 2017-04-16 | 再生元醫藥公司 | 抗ａｎｇｐｔｌ８抗體及其用途 |
| EP3368090A1 (en) | 2015-10-30 | 2018-09-05 | H. Hoffnabb-La Roche Ag | Anti-factor d antibody variant conjugates and uses thereof |
| EP3368074A2 (en) | 2015-10-30 | 2018-09-05 | Hoffmann-La Roche AG | Anti-factor d antibodies and conjugates |
| KR20190078650A (ko) | 2016-11-17 | 2019-07-04 | 리제너론 파아마슈티컬스, 인크. | 항-angptl8 항체를 사용하는 비만의 치료 방법 |
| WO2019126194A1 (en) | 2017-12-18 | 2019-06-27 | Regeneron Pharmaceuticals, Inc. | Angptl8 assay and uses thereof |
| CN112980883B (zh) * | 2021-03-03 | 2022-04-12 | 广州达博生物制品有限公司 | 一种人γ-干扰素病毒载体及其应用 |
| WO2022261348A1 (en) * | 2021-06-11 | 2022-12-15 | Monsanto Technology Llc | Methods and compositions for altering protein accumulation |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5001225A (en) * | 1986-12-08 | 1991-03-19 | Georgetown University | Monoclonal antibodies to a pan-malarial antigen |
| US5118617A (en) * | 1989-05-19 | 1992-06-02 | Applied Research Systems Ars Holding N.V. | Saf polypeptide, gene coding therefor, saf promoter and expression methods for expressing foreign dna sequences in streptomyces |
| JP2879303B2 (ja) * | 1993-01-14 | 1999-04-05 | 佑 本庶 | ｃＤＮＡライブラリーの作製方法、および新規なポリペプチドとそれをコードするＤＮＡ |
| US5536637A (en) * | 1993-04-07 | 1996-07-16 | Genetics Institute, Inc. | Method of screening for cDNA encoding novel secreted mammalian proteins in yeast |
| US5744355A (en) * | 1994-10-18 | 1998-04-28 | Mayo Foundation For Medical Education And Research | cDNA cloning and expression of human liver estrogen sulfotransferase |
| US5707829A (en) * | 1995-08-11 | 1998-01-13 | Genetics Institute, Inc. | DNA sequences and secreted proteins encoded thereby |
| WO1999040100A1 (en) | 1998-02-09 | 1999-08-12 | Human Genome Sciences, Inc. | 45 human secreted proteins |
| US20060223088A1 (en) * | 1997-03-07 | 2006-10-05 | Rosen Craig A | Human secreted proteins |
| AU6956798A (en) * | 1997-04-10 | 1998-10-30 | Genetics Institute Inc. | Secreted expressed sequence tags (sests) |
| US20030073129A1 (en) * | 1998-09-01 | 2003-04-17 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| AU764441B2 (en) | 1998-02-09 | 2003-08-21 | Genset S.A. | cDNAs encoding secreted proteins |
| EP1090118A2 (en) | 1998-06-26 | 2001-04-11 | Incyte Pharmaceuticals, Inc. | Human signal peptide-containing proteins |
| NZ510464A (en) | 1998-09-01 | 2004-05-28 | Genentech Inc | Further pro polypeptides and sequences thereof |
| DK1607402T3 (da) | 1999-03-08 | 2007-04-16 | Genentech Inc | Sammensætninger og fremgangsmåder til tumorbehandling |
| EP1130094A3 (en) | 1999-07-08 | 2001-11-21 | Helix Research Institute | Primers for synthesizing full length cDNA clones and their use |
| CA2402563A1 (en) | 1999-12-23 | 2001-07-26 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
| US20020039760A1 (en) | 2000-04-06 | 2002-04-04 | Wong Gorden G. | Polynucleotides encoding novel secreted proteins |
| US6812339B1 (en) * | 2000-09-08 | 2004-11-02 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| US8067152B2 (en) * | 2006-02-27 | 2011-11-29 | The Fred Hutchinson Cancer Research Center | Liver cancer biomarkers |
-
1999
- 1999-02-04 WO PCT/US1999/002293 patent/WO1999040100A1/en not_active Ceased
- 1999-02-04 CA CA002320625A patent/CA2320625A1/en not_active Abandoned
- 1999-02-04 AU AU25777/99A patent/AU2577799A/en not_active Abandoned
- 1999-02-04 JP JP2000530528A patent/JP2002502589A/ja active Pending
- 1999-02-04 EP EP99905667A patent/EP1053245A4/en not_active Withdrawn
- 1999-08-05 US US09/369,247 patent/US6569992B1/en not_active Expired - Fee Related
-
2002
- 2002-02-05 US US10/062,548 patent/US6924356B2/en not_active Expired - Fee Related
-
2004
- 2004-08-16 US US10/918,446 patent/US20050009085A1/en not_active Abandoned
- 2004-12-03 US US11/002,756 patent/US20050153335A1/en not_active Abandoned
- 2004-12-03 US US11/002,755 patent/US20050079537A1/en not_active Abandoned
- 2004-12-03 US US11/002,754 patent/US20060281095A1/en not_active Abandoned
-
2006
- 2006-12-11 US US11/608,978 patent/US20070154918A1/en not_active Abandoned
-
2008
- 2008-11-20 US US12/274,626 patent/US20090088555A1/en not_active Abandoned