JP2006101875A5 - - Google Patents
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- JP2006101875A5 JP2006101875A5 JP2005262178A JP2005262178A JP2006101875A5 JP 2006101875 A5 JP2006101875 A5 JP 2006101875A5 JP 2005262178 A JP2005262178 A JP 2005262178A JP 2005262178 A JP2005262178 A JP 2005262178A JP 2006101875 A5 JP2006101875 A5 JP 2006101875A5
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- JP
- Japan
- Prior art keywords
- amino acid
- seq
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- mutation
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 230000035772 mutation Effects 0.000 claims description 20
- 241000186254 coryneform bacterium Species 0.000 claims description 11
- 150000001413 amino acids Chemical group 0.000 description 45
- 108090000623 proteins and genes Proteins 0.000 description 31
- 239000002773 nucleotide Substances 0.000 description 30
- 125000003729 nucleotide group Chemical group 0.000 description 30
- 108020004306 Alpha-ketoglutarate dehydrogenase Proteins 0.000 description 20
- 102000006589 Alpha-ketoglutarate dehydrogenase Human genes 0.000 description 19
- 102000004169 proteins and genes Human genes 0.000 description 18
- 229940024606 amino acid Drugs 0.000 description 17
- 230000000694 effects Effects 0.000 description 10
- 101150021317 odhA gene Proteins 0.000 description 10
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 8
- 125000000539 amino acid group Chemical group 0.000 description 7
- 230000001747 exhibiting effect Effects 0.000 description 5
- 239000000523 sample Substances 0.000 description 5
- 229960002989 glutamic acid Drugs 0.000 description 4
- 108091033319 polynucleotide Proteins 0.000 description 3
- 239000002157 polynucleotide Substances 0.000 description 3
- 102000040430 polynucleotide Human genes 0.000 description 3
- KPGXRSRHYNQIFN-UHFFFAOYSA-N 2-oxoglutaric acid Chemical class OC(=O)CCC(=O)C(O)=O KPGXRSRHYNQIFN-UHFFFAOYSA-N 0.000 description 2
- 241000186031 Corynebacteriaceae Species 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000003834 intracellular effect Effects 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 101150111745 sucA gene Proteins 0.000 description 2
- 108091026890 Coding region Proteins 0.000 description 1
- 101710088194 Dehydrogenase Proteins 0.000 description 1
- 210000000349 chromosome Anatomy 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229960002363 thiamine pyrophosphate Drugs 0.000 description 1
- 235000008170 thiamine pyrophosphate Nutrition 0.000 description 1
- 239000011678 thiamine pyrophosphate Substances 0.000 description 1
- YXVCLPJQTZXJLH-UHFFFAOYSA-N thiamine(1+) diphosphate chloride Chemical compound [Cl-].CC1=C(CCOP(O)(=O)OP(O)(O)=O)SC=[N+]1CC1=CN=C(C)N=C1N YXVCLPJQTZXJLH-UHFFFAOYSA-N 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005262178A JP2006101875A (ja) | 2004-09-10 | 2005-09-09 | L−グルタミン酸生産菌及びl−グルタミン酸の製造方法 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004264458 | 2004-09-10 | ||
| JP2005262178A JP2006101875A (ja) | 2004-09-10 | 2005-09-09 | L−グルタミン酸生産菌及びl−グルタミン酸の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006101875A JP2006101875A (ja) | 2006-04-20 |
| JP2006101875A5 true JP2006101875A5 (https=) | 2008-08-21 |
Family
ID=35734913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005262178A Pending JP2006101875A (ja) | 2004-09-10 | 2005-09-09 | L−グルタミン酸生産菌及びl−グルタミン酸の製造方法 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1786899B1 (https=) |
| JP (1) | JP2006101875A (https=) |
| KR (1) | KR100930842B1 (https=) |
| CN (1) | CN101010423B (https=) |
| BR (1) | BRPI0515035A (https=) |
| WO (1) | WO2006028298A2 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR122020021800B1 (pt) * | 2004-12-28 | 2021-05-04 | Ajinomoto Co., Inc | Método para produzir ácido l-glutâmico |
| JP2010041920A (ja) | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP2010130899A (ja) | 2007-03-14 | 2010-06-17 | Ajinomoto Co Inc | L−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法 |
| WO2009103547A1 (en) | 2008-02-21 | 2009-08-27 | Basf Se | Process for the production of gamma-aminobutyric acid |
| BR112013016373B1 (pt) | 2011-11-11 | 2021-05-18 | Ajinomoto Co., Inc | método para produzir uma substância alvo |
| JP2016165225A (ja) | 2013-07-09 | 2016-09-15 | 味の素株式会社 | 有用物質の製造方法 |
| JP2016192903A (ja) | 2013-09-17 | 2016-11-17 | 味の素株式会社 | 海藻由来バイオマスからのl−アミノ酸の製造方法 |
| KR101547651B1 (ko) * | 2014-06-03 | 2015-08-26 | 씨제이제일제당 주식회사 | O-숙시닐호모세린 또는 숙신산의 생산능을 갖는 미생물 및 이를 이용한 숙신산 또는 o-숙시닐호모세린의 생산 방법 |
| CN108250278B (zh) * | 2016-12-29 | 2021-06-22 | 廊坊梅花生物技术开发有限公司 | 生产l-谷氨酸的菌株和生产l-谷氨酸的方法 |
| KR102008673B1 (ko) * | 2017-12-07 | 2019-08-09 | 대상 주식회사 | 락토바실러스 퍼멘텀 c-7a 균주 및 이의 용도 |
| CN113637699B (zh) * | 2020-04-27 | 2023-05-30 | 中国科学院分子植物科学卓越创新中心 | 一种提高氨基酸产生菌生产能力的方法 |
| BR112023004335A2 (pt) * | 2020-09-09 | 2023-04-04 | Cj Cheiljedang Corp | Microrganismo recombinante para produzir ácido l-glutâmico e um método para produzir ácido l-glutâmico usando o mesmo |
| CN112646767B (zh) * | 2020-12-30 | 2022-08-09 | 宁夏伊品生物科技股份有限公司 | 具有增强的l-谷氨酸生产力的菌株及其构建方法与应用 |
| KR102665227B1 (ko) * | 2021-06-30 | 2024-05-10 | 씨제이제일제당 주식회사 | 고농도 l-글루탐산을 생산하기 위한 균주 및 이를 이용한 l-글루탐산 생산방법 |
| KR20250117262A (ko) | 2024-01-25 | 2025-08-04 | 대상 주식회사 | L-시트룰린 또는 l-아르기닌 생산능이 향상된 변이 미생물 및 이를 이용한 l-시트룰린 또는 l-아르기닌의 생산 방법 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5977331A (en) * | 1994-06-14 | 1999-11-02 | Ajinomoto Co., Inc. | α-Ketoglutarate dehydrogenase gene |
-
2005
- 2005-09-09 EP EP05783597A patent/EP1786899B1/en not_active Expired - Lifetime
- 2005-09-09 JP JP2005262178A patent/JP2006101875A/ja active Pending
- 2005-09-09 KR KR1020077008186A patent/KR100930842B1/ko not_active Expired - Fee Related
- 2005-09-09 WO PCT/JP2005/017098 patent/WO2006028298A2/en not_active Ceased
- 2005-09-09 BR BRPI0515035-3A patent/BRPI0515035A/pt not_active IP Right Cessation
- 2005-09-09 CN CN2005800298560A patent/CN101010423B/zh not_active Expired - Fee Related
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