BRPI0515035A - bactéria corineforme produtora de ácido l-glutámico, método para produzir ácido l-glutámico, gene codificador de alfa-ceto-glutarato desidrogenase mutante, e, alfa-ceto-glutarato desidrogenase mutante - Google Patents
bactéria corineforme produtora de ácido l-glutámico, método para produzir ácido l-glutámico, gene codificador de alfa-ceto-glutarato desidrogenase mutante, e, alfa-ceto-glutarato desidrogenase mutanteInfo
- Publication number
- BRPI0515035A BRPI0515035A BRPI0515035-3A BRPI0515035A BRPI0515035A BR PI0515035 A BRPI0515035 A BR PI0515035A BR PI0515035 A BRPI0515035 A BR PI0515035A BR PI0515035 A BRPI0515035 A BR PI0515035A
- Authority
- BR
- Brazil
- Prior art keywords
- keto
- glutamic acid
- producing
- glutarate
- glutarate dehydrogenase
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/14—Glutamic acid; Glutamine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
BACTéRIA CORINEFORME PRODUTORA DE áCIDO L-GLUTáMICO, MéTODO PARA PRODUZIR áCIDO L-GLUTáMICO, GENE CODIFICADOR DE ALFA-CETO-GLUTARATO DESIDROGENASE MUTANTE, E, ALFA-CETO-GLUTARATO DESIDROGENASE MUTANTE". Uma bactéria corineforme que possui uma capacidade de produção de ácido L-glutâmico e cresce pelo menos na mesma velocidade de crescimento que a de uma cepa não-mutada ou de uma cepa de tipo selvagem e possui atividade de <244>-ceto-glutarato desidrogenase intracelular que é menor do que a metade daquela da cepa não-mutada ou de tipo selvagem, e é obtida pela introdução de uma mutação em uma região codificadora ou uma região de controle de expressão do gene odhA cromossómico codificador da subunidade Elo do complexo de <244>-ceto-glutarato desidrogenase.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004264458 | 2004-09-10 | ||
| PCT/JP2005/017098 WO2006028298A2 (en) | 2004-09-10 | 2005-09-09 | L-glutamic acid-producing microorganism and a method for producing l-glutamic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0515035A true BRPI0515035A (pt) | 2008-07-01 |
Family
ID=35734913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0515035-3A BRPI0515035A (pt) | 2004-09-10 | 2005-09-09 | bactéria corineforme produtora de ácido l-glutámico, método para produzir ácido l-glutámico, gene codificador de alfa-ceto-glutarato desidrogenase mutante, e, alfa-ceto-glutarato desidrogenase mutante |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1786899B1 (pt) |
| JP (1) | JP2006101875A (pt) |
| KR (1) | KR100930842B1 (pt) |
| CN (1) | CN101010423B (pt) |
| BR (1) | BRPI0515035A (pt) |
| WO (1) | WO2006028298A2 (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006070944A2 (en) * | 2004-12-28 | 2006-07-06 | Ajinomoto Co., Inc. | L-glutamic acid-producing microorganism and a method for producing l-glutamic acid |
| JP2010041920A (ja) | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP2010130899A (ja) | 2007-03-14 | 2010-06-17 | Ajinomoto Co Inc | Ｌ−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法 |
| JP2011512144A (ja) | 2008-02-21 | 2011-04-21 | ビーエーエスエフ ソシエタス・ヨーロピア | γ−アミノ酪酸の生産方法 |
| BR112013016373B1 (pt) | 2011-11-11 | 2021-05-18 | Ajinomoto Co., Inc | método para produzir uma substância alvo |
| JP2016165225A (ja) | 2013-07-09 | 2016-09-15 | 味の素株式会社 | 有用物質の製造方法 |
| JP2016192903A (ja) | 2013-09-17 | 2016-11-17 | 味の素株式会社 | 海藻由来バイオマスからのｌ−アミノ酸の製造方法 |
| KR101547651B1 (ko) * | 2014-06-03 | 2015-08-26 | 씨제이제일제당 주식회사 | O-숙시닐호모세린 또는 숙신산의 생산능을 갖는 미생물 및 이를 이용한 숙신산 또는 o-숙시닐호모세린의 생산 방법 |
| CN108250278B (zh) * | 2016-12-29 | 2021-06-22 | 廊坊梅花生物技术开发有限公司 | 生产l-谷氨酸的菌株和生产l-谷氨酸的方法 |
| KR102008673B1 (ko) * | 2017-12-07 | 2019-08-09 | 대상 주식회사 | 락토바실러스 퍼멘텀 c-7a 균주 및 이의 용도 |
| CN113637699B (zh) * | 2020-04-27 | 2023-05-30 | 中国科学院分子植物科学卓越创新中心 | 一种提高氨基酸产生菌生产能力的方法 |
| CN112646767B (zh) * | 2020-12-30 | 2022-08-09 | 宁夏伊品生物科技股份有限公司 | 具有增强的l-谷氨酸生产力的菌株及其构建方法与应用 |
| KR102665227B1 (ko) * | 2021-06-30 | 2024-05-10 | 씨제이제일제당 주식회사 | 고농도 l-글루탐산을 생산하기 위한 균주 및 이를 이용한 l-글루탐산 생산방법 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1177926C (zh) * | 1994-06-14 | 2004-12-01 | 味之素株式会社 | 产l-谷氨酸棒状细菌及生产l-谷氨酸的方法 |
-
2005
- 2005-09-09 CN CN2005800298560A patent/CN101010423B/zh not_active Expired - Fee Related
- 2005-09-09 BR BRPI0515035-3A patent/BRPI0515035A/pt not_active IP Right Cessation
- 2005-09-09 EP EP05783597A patent/EP1786899B1/en not_active Not-in-force
- 2005-09-09 JP JP2005262178A patent/JP2006101875A/ja active Pending
- 2005-09-09 KR KR1020077008186A patent/KR100930842B1/ko not_active IP Right Cessation
- 2005-09-09 WO PCT/JP2005/017098 patent/WO2006028298A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006028298A3 (en) | 2006-04-27 |
| KR100930842B1 (ko) | 2009-12-10 |
| CN101010423A (zh) | 2007-08-01 |
| EP1786899A2 (en) | 2007-05-23 |
| WO2006028298A2 (en) | 2006-03-16 |
| EP1786899B1 (en) | 2012-06-27 |
| KR20070053321A (ko) | 2007-05-23 |
| JP2006101875A (ja) | 2006-04-20 |
| CN101010423B (zh) | 2012-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 4A, 5A E 6A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012. |