BRPI0500729A - processo para a produção de l-aminoácidos usando as bactérias corineformes - Google Patents

processo para a produção de l-aminoácidos usando as bactérias corineformes

Info

Publication number
BRPI0500729A
BRPI0500729A BRPI0500729-1A BRPI0500729A BRPI0500729A BR PI0500729 A BRPI0500729 A BR PI0500729A BR PI0500729 A BRPI0500729 A BR PI0500729A BR PI0500729 A BRPI0500729 A BR PI0500729A
Authority
BR
Brazil
Prior art keywords
bacteria
production
amino acid
amino acids
coryneform bacteria
Prior art date
Application number
BRPI0500729-1A
Other languages
English (en)
Inventor
Brigitte Bathe
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of BRPI0500729A publication Critical patent/BRPI0500729A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"PROCESSO PARA A PRODUçãO DE L-AMINOáCIDOS USANDO AS BACTéRIAS CORINEFORMES". A presente invenção refere-se a um processo para a produção de L-aminoácidos, no qual são realizadas as seguintes etapas: a) fermentação das bactérias corineformes que produzem o Laminoácido desejado, em cujas bactérias pelo menos o gene codificando o regulador de transcrição TipA é atenuado, b) concentração do L-aminoácido desejado no meio ou nas células das bactérias, e c) isolamento do L-aminoácido, e opcionalmente são usadas bactérias nas quais genes adicionais da via de biossíntese do L-aminoácido desejado são adicionalmente aumentados, ou são usadas bactérias nas quais as vias metabólicas que reduzem a formação do L-aminoácido desejado são pelo menos parcialmente excluídas.
BRPI0500729-1A 2004-03-09 2005-03-08 processo para a produção de l-aminoácidos usando as bactérias corineformes BRPI0500729A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004011248A DE102004011248A1 (de) 2004-03-09 2004-03-09 Verfahren zur Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien

Publications (1)

Publication Number Publication Date
BRPI0500729A true BRPI0500729A (pt) 2006-04-18

Family

ID=34813614

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0500729-1A BRPI0500729A (pt) 2004-03-09 2005-03-08 processo para a produção de l-aminoácidos usando as bactérias corineformes

Country Status (5)

Country Link
US (1) US20050221454A1 (pt)
EP (1) EP1574582A1 (pt)
CN (1) CN1680564A (pt)
BR (1) BRPI0500729A (pt)
DE (1) DE102004011248A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE443757T1 (de) * 2004-01-30 2009-10-15 Ajinomoto Kk L-aminosäure produzierender mikroorganismus und verfahren zur l-aminosäureproduktion
KR100789272B1 (ko) 2005-12-03 2008-01-02 씨제이 주식회사 Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용하여 ｌ-라이신을 생산하는 방법
KR100838038B1 (ko) * 2006-12-29 2008-06-12 씨제이제일제당 (주) Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 ｌ-라이신 생산 방법
BRPI0819273B8 (pt) * 2007-11-20 2022-07-19 Dsm Ip Assets Bv Célula microbiana eucariótica recombinante e processo para a preparação de um ácido dicarboxílico
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
CN105483145B (zh) * 2011-12-21 2021-04-06 Cj第一制糖株式会社 利用具有产生l-赖氨酸能力的微生物产生l-赖氨酸的方法
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
EP4194545A1 (en) * 2020-08-07 2023-06-14 Ningxia Eppen Biotech Co. Ltd Recombinant strain for producing l-amino acid, and construction method therefor and use thereof
CN112063571B (zh) * 2020-08-14 2022-05-06 廊坊梅花生物技术开发有限公司 高产l-氨基酸的工程菌及其构建方法与应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020028490A1 (en) * 1999-03-19 2002-03-07 Douwe Molenaar Process for the production of L-amino acids by fermentation using coryneform bacteria
JP4526710B2 (ja) * 1999-04-19 2010-08-18 協和発酵バイオ株式会社 新規な脱感作型アスパルトキナーゼ
US6872553B2 (en) * 1999-10-20 2005-03-29 Degussa Ag Nucleotide sequences which code for the pck gene
DE19950409A1 (de) * 1999-10-20 2001-04-26 Degussa Neue für das pck-Gen codierende Nukleotidsequenzen
DE19959328A1 (de) * 1999-12-09 2001-06-13 Degussa Neue für das zwa1-Gen codierende Nukleotidsequenzen
DE19959327A1 (de) * 1999-12-09 2001-06-13 Degussa Neue für das zwa2-Gen codierende Nukleotidsequenzen
AU2001279769A1 (en) * 2000-08-31 2002-03-13 Degussa A.G. Citb gene from corynebacteria and use thereof in synthesis of l-amino acids
US7049106B2 (en) * 2001-04-10 2006-05-23 Degussa Ag Process for the production of L-amino acids by fermentation using coryneform bacteria with an attenuated mqo gene
DE10117816A1 (de) * 2001-04-10 2002-10-17 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
DE10126164A1 (de) * 2001-05-30 2002-12-05 Degussa Für das metD-gen kodierende Nukleotidsequenzen

Also Published As

Publication number Publication date
CN1680564A (zh) 2005-10-12
EP1574582A1 (de) 2005-09-14
DE102004011248A1 (de) 2005-09-22
US20050221454A1 (en) 2005-10-06

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]