JP2004500074A5 - - Google Patents

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Publication number
JP2004500074A5
JP2004500074A5 JP2001551215A JP2001551215A JP2004500074A5 JP 2004500074 A5 JP2004500074 A5 JP 2004500074A5 JP 2001551215 A JP2001551215 A JP 2001551215A JP 2001551215 A JP2001551215 A JP 2001551215A JP 2004500074 A5 JP2004500074 A5 JP 2004500074A5
Authority
JP
Japan
Prior art keywords
seq
polypeptide
nucleic acid
composition
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001551215A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004500074A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2001/001171 external-priority patent/WO2001051641A1/en
Publication of JP2004500074A publication Critical patent/JP2004500074A/ja
Publication of JP2004500074A5 publication Critical patent/JP2004500074A5/ja
Pending legal-status Critical Current

Links

JP2001551215A 2000-01-13 2001-01-12 Irak−4:組成物および使用方法 Pending JP2004500074A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17639500P 2000-01-13 2000-01-13
PCT/US2001/001171 WO2001051641A1 (en) 2000-01-13 2001-01-12 Irak-4: compositions and methods of use

Publications (2)

Publication Number Publication Date
JP2004500074A JP2004500074A (ja) 2004-01-08
JP2004500074A5 true JP2004500074A5 (https=) 2008-02-07

Family

ID=22644182

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001551215A Pending JP2004500074A (ja) 2000-01-13 2001-01-12 Irak−4:組成物および使用方法

Country Status (8)

Country Link
US (2) US6818419B2 (https=)
EP (1) EP1248847B8 (https=)
JP (1) JP2004500074A (https=)
AT (1) ATE390485T1 (https=)
AU (1) AU783742B2 (https=)
CA (1) CA2397481A1 (https=)
DE (1) DE60133366T2 (https=)
WO (1) WO2001051641A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6692959B2 (en) 1998-11-25 2004-02-17 Isis Pharmaceuticals, Inc. Antisense modulation of IL-1 receptor-associated kinase-4 expression
WO2002040680A2 (en) * 2000-11-17 2002-05-23 The Burnham Institute Death domain proteins
US6965023B2 (en) * 2000-11-17 2005-11-15 The Burnham Institute Death domain proteins
ES2367422T3 (es) 2001-10-09 2011-11-03 Amgen Inc. Derivados de imidazol como agentes antiinflamatorios.
WO2003045228A2 (en) 2001-11-26 2003-06-05 Trustees Of Tufts College Methods for treating autoimmune disorders, and reagents related thereto
WO2005052132A2 (en) * 2003-11-24 2005-06-09 Exelixis, Inc Mbms as modifiers of branching morphogenesis and methods of use
US20100279316A1 (en) * 2007-01-19 2010-11-04 Leonid Gorelik Antibodies to Phosphorylated IRAK4
EP2243481A1 (en) * 2009-04-24 2010-10-27 PamGene B.V. Irak kinase family as novel drug target for Alzheimer
DE102009033208A1 (de) 2009-07-15 2011-01-20 Merck Patent Gmbh Aminopyridinderivate
EP3267996B1 (en) 2015-03-12 2020-11-11 Merck Sharp & Dohme Corp. Pyrazolopyrimidine inhibitors of irak4 activity
EP3268003B1 (en) 2015-03-12 2020-07-29 Merck Sharp & Dohme Corp. Thienopyrazine inhibitors of irak4 activity
US10155765B2 (en) 2015-03-12 2018-12-18 Merck Sharp & Dohme Corp. Carboxamide inhibitors of IRAK4 activity
WO2017205762A1 (en) 2016-05-27 2017-11-30 Pharmacyclics Llc Inhibitors of interleukin-1 receptor-associated kinase
WO2017205769A1 (en) 2016-05-27 2017-11-30 Pharmacyclics Llc Inhibitors of interleukin-1 receptor-associated kinase
WO2017205766A1 (en) 2016-05-27 2017-11-30 Pharmacyclics Llc Inhibitors of interleukin-1 receptor-associated kinase
CN119630802A (zh) 2022-04-12 2025-03-14 建新公司 Irak4调节剂用于基因疗法的用途
CA3251930A1 (en) * 2022-05-11 2023-11-16 Curis, Inc. TREATMENT OF DISEASES AND DISORDERS WITH MIRACLES MODIFYING COMPOUNDS 4
CN118909142A (zh) * 2024-08-07 2024-11-08 北京爱思益普生物科技股份有限公司 Irak4蛋白的制备方法及其所采用的融合蛋白

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998044113A1 (en) 1997-03-28 1998-10-08 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
US5965421A (en) 1997-11-26 1999-10-12 Human Genome Sciences, Inc. Human IRAK-2
ES2262321T3 (es) 1998-05-15 2006-11-16 Ortho-Mcneil Pharmaceutical, Inc. Ratones transgenicos portadores de un gen irak modificado.
KR20010083890A (ko) 1998-10-05 2001-09-03 에드워드 에이. 맥더모트, 주니어 암 관련 항원 및 그의 용도
US6440663B1 (en) * 1998-10-05 2002-08-27 Ludwig Institute For Cancer Research Renal cancer associated antigens and uses therefor
EP1259812A2 (en) 1999-05-28 2002-11-27 Ludwig Institute For Cancer Research Breast, gastric and prostate cancer associated antigens and uses therefor

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