DE60133366T2 - Irak-4 zusammensetzungen und deren verwendungen - Google Patents
Irak-4 zusammensetzungen und deren verwendungen Download PDFInfo
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- DE60133366T2 DE60133366T2 DE60133366T DE60133366T DE60133366T2 DE 60133366 T2 DE60133366 T2 DE 60133366T2 DE 60133366 T DE60133366 T DE 60133366T DE 60133366 T DE60133366 T DE 60133366T DE 60133366 T2 DE60133366 T2 DE 60133366T2
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| US17639500P | 2000-01-13 | 2000-01-13 | |
| US176395P | 2000-01-13 | ||
| PCT/US2001/001171 WO2001051641A1 (en) | 2000-01-13 | 2001-01-12 | Irak-4: compositions and methods of use |
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| DE60133366D1 DE60133366D1 (de) | 2008-05-08 |
| DE60133366T2 true DE60133366T2 (de) | 2008-10-02 |
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| US6692959B2 (en) | 1998-11-25 | 2004-02-17 | Isis Pharmaceuticals, Inc. | Antisense modulation of IL-1 receptor-associated kinase-4 expression |
| WO2002040680A2 (en) * | 2000-11-17 | 2002-05-23 | The Burnham Institute | Death domain proteins |
| US6965023B2 (en) * | 2000-11-17 | 2005-11-15 | The Burnham Institute | Death domain proteins |
| ES2367422T3 (es) | 2001-10-09 | 2011-11-03 | Amgen Inc. | Derivados de imidazol como agentes antiinflamatorios. |
| WO2003045228A2 (en) | 2001-11-26 | 2003-06-05 | Trustees Of Tufts College | Methods for treating autoimmune disorders, and reagents related thereto |
| WO2005052132A2 (en) * | 2003-11-24 | 2005-06-09 | Exelixis, Inc | Mbms as modifiers of branching morphogenesis and methods of use |
| US20100279316A1 (en) * | 2007-01-19 | 2010-11-04 | Leonid Gorelik | Antibodies to Phosphorylated IRAK4 |
| EP2243481A1 (en) * | 2009-04-24 | 2010-10-27 | PamGene B.V. | Irak kinase family as novel drug target for Alzheimer |
| DE102009033208A1 (de) | 2009-07-15 | 2011-01-20 | Merck Patent Gmbh | Aminopyridinderivate |
| EP3267996B1 (en) | 2015-03-12 | 2020-11-11 | Merck Sharp & Dohme Corp. | Pyrazolopyrimidine inhibitors of irak4 activity |
| EP3268003B1 (en) | 2015-03-12 | 2020-07-29 | Merck Sharp & Dohme Corp. | Thienopyrazine inhibitors of irak4 activity |
| US10155765B2 (en) | 2015-03-12 | 2018-12-18 | Merck Sharp & Dohme Corp. | Carboxamide inhibitors of IRAK4 activity |
| WO2017205762A1 (en) | 2016-05-27 | 2017-11-30 | Pharmacyclics Llc | Inhibitors of interleukin-1 receptor-associated kinase |
| WO2017205769A1 (en) | 2016-05-27 | 2017-11-30 | Pharmacyclics Llc | Inhibitors of interleukin-1 receptor-associated kinase |
| WO2017205766A1 (en) | 2016-05-27 | 2017-11-30 | Pharmacyclics Llc | Inhibitors of interleukin-1 receptor-associated kinase |
| CN119630802A (zh) | 2022-04-12 | 2025-03-14 | 建新公司 | Irak4调节剂用于基因疗法的用途 |
| CA3251930A1 (en) * | 2022-05-11 | 2023-11-16 | Curis, Inc. | TREATMENT OF DISEASES AND DISORDERS WITH MIRACLES MODIFYING COMPOUNDS 4 |
| CN118909142A (zh) * | 2024-08-07 | 2024-11-08 | 北京爱思益普生物科技股份有限公司 | Irak4蛋白的制备方法及其所采用的融合蛋白 |
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| WO1998044113A1 (en) | 1997-03-28 | 1998-10-08 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
| US5965421A (en) | 1997-11-26 | 1999-10-12 | Human Genome Sciences, Inc. | Human IRAK-2 |
| ES2262321T3 (es) | 1998-05-15 | 2006-11-16 | Ortho-Mcneil Pharmaceutical, Inc. | Ratones transgenicos portadores de un gen irak modificado. |
| KR20010083890A (ko) | 1998-10-05 | 2001-09-03 | 에드워드 에이. 맥더모트, 주니어 | 암 관련 항원 및 그의 용도 |
| US6440663B1 (en) * | 1998-10-05 | 2002-08-27 | Ludwig Institute For Cancer Research | Renal cancer associated antigens and uses therefor |
| EP1259812A2 (en) | 1999-05-28 | 2002-11-27 | Ludwig Institute For Cancer Research | Breast, gastric and prostate cancer associated antigens and uses therefor |
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