JP2005539023A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005539023A5 JP2005539023A5 JP2004527531A JP2004527531A JP2005539023A5 JP 2005539023 A5 JP2005539023 A5 JP 2005539023A5 JP 2004527531 A JP2004527531 A JP 2004527531A JP 2004527531 A JP2004527531 A JP 2004527531A JP 2005539023 A5 JP2005539023 A5 JP 2005539023A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- hydrocarbyl
- group
- halo
- cyano
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- UJLPVGLFJFFLCR-UHFFFAOYSA-N NS(c(cc1)ccc1-[n]1nccc1)(=O)=O Chemical compound NS(c(cc1)ccc1-[n]1nccc1)(=O)=O UJLPVGLFJFFLCR-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/213,793 US20030100594A1 (en) | 2001-08-10 | 2002-08-07 | Carbonic anhydrase inhibitor |
| PCT/US2003/004494 WO2004014352A2 (en) | 2002-08-07 | 2003-02-14 | Methods for treating carbonic anhydrase mediated disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005539023A JP2005539023A (ja) | 2005-12-22 |
| JP2005539023A5 true JP2005539023A5 (https=) | 2006-03-30 |
Family
ID=31714232
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004527530A Withdrawn JP2005539022A (ja) | 2002-08-07 | 2003-02-14 | 悪性腫瘍の治療のためのシクロオキシゲナーゼ−2選択的阻害剤及びカルボニックアンヒドラーゼ阻害剤の組成物 |
| JP2004527531A Withdrawn JP2005539023A (ja) | 2002-08-07 | 2003-02-14 | 炭酸脱水酵素媒介疾患の治療方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004527530A Withdrawn JP2005539022A (ja) | 2002-08-07 | 2003-02-14 | 悪性腫瘍の治療のためのシクロオキシゲナーゼ−2選択的阻害剤及びカルボニックアンヒドラーゼ阻害剤の組成物 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20030100594A1 (https=) |
| EP (2) | EP1526869A1 (https=) |
| JP (2) | JP2005539022A (https=) |
| KR (1) | KR20050056189A (https=) |
| CN (1) | CN1681557A (https=) |
| AU (2) | AU2003225571A1 (https=) |
| BR (2) | BR0313282A (https=) |
| CA (2) | CA2495516A1 (https=) |
| IL (1) | IL166685A0 (https=) |
| MX (2) | MXPA05001496A (https=) |
| PL (1) | PL374994A1 (https=) |
| WO (2) | WO2004014430A1 (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10035227A1 (de) * | 2000-07-20 | 2002-01-31 | Solvay Pharm Gmbh | Verfahren zum Auffinden von Verbindungen, welche zur Behandlung und/oder Prophylaxe von Fettleibigkeit geeignet sind |
| US6946243B2 (en) * | 2000-07-20 | 2005-09-20 | Solvay Pharmaceuticals Gmbh | Method of identifying compounds suitable for treatment and/or prophylaxis of obesity |
| US20100135980A1 (en) * | 2000-10-16 | 2010-06-03 | Rodriguez Victorio C | Therapeutic and prophylactic uses of cell specific carbonic anhydrase enzymes in treating aging, disorders of aging, cancer, as growth factors, and as an alternative to stem cell therapy |
| US20030220376A1 (en) * | 2001-08-10 | 2003-11-27 | Pharmacia Corporation | Methods for treating carbonic anhydrase mediated disorders |
| PT1636236E (pt) * | 2003-05-22 | 2013-12-16 | Nerviano Medical Sciences Srl | Derivados de pirazol-quinazolina, processo para sua preparação e sua utilização como inibidores de cinase |
| WO2005079781A1 (en) * | 2004-02-25 | 2005-09-01 | La Trobe University | Therapeutic and/or prophylactic method |
| WO2005094815A1 (en) * | 2004-03-30 | 2005-10-13 | Amorepacific Corporation | Dual inhibition of cyclooxygenase-2 and carbonic anhydrase |
| US7799336B2 (en) * | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
| US8722097B2 (en) | 2004-04-30 | 2014-05-13 | Allergan, Inc. | Oil-in-water method for making polymeric implants containing a hypotensive lipid |
| US8673341B2 (en) | 2004-04-30 | 2014-03-18 | Allergan, Inc. | Intraocular pressure reduction with intracameral bimatoprost implants |
| US7993634B2 (en) | 2004-04-30 | 2011-08-09 | Allergan, Inc. | Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods |
| US9498457B2 (en) | 2004-04-30 | 2016-11-22 | Allergan, Inc. | Hypotensive prostamide-containing biodegradable intraocular implants and related implants |
| MY147767A (en) | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| JP2008545650A (ja) | 2005-05-20 | 2008-12-18 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | スルファミド誘導体の製造方法 |
| JP4872076B2 (ja) * | 2005-09-15 | 2012-02-08 | 国立大学法人 長崎大学 | 硝子体可視化剤 |
| US20070155823A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents |
| US8937096B2 (en) | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
| US8691867B2 (en) | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
| US8497298B2 (en) | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
| EP2026790A2 (en) | 2006-05-19 | 2009-02-25 | Janssen Pharmaceutica, N.V. | Co-therapy for the treatment of epilepsy and related disorders |
| US8969415B2 (en) | 2006-12-01 | 2015-03-03 | Allergan, Inc. | Intraocular drug delivery systems |
| WO2008075148A2 (en) * | 2006-12-15 | 2008-06-26 | Pfizer Products Inc. | Tricyclic inhibitors of carbonic anhydrase |
| CA2711678A1 (en) * | 2008-01-09 | 2009-07-16 | Molecular Insight Pharmaceuticals, Inc. | Inhibitors of carbonic anhydrase ix |
| US8809385B2 (en) | 2008-06-23 | 2014-08-19 | Janssen Pharmaceutica Nv | Crystalline form of (2S)-(-)-N-(6-chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-sulfamide |
| US8815939B2 (en) | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
| WO2010065899A2 (en) | 2008-12-05 | 2010-06-10 | Molecular Insight Pharmaceuticals, Inc. | Technetium-and rhenium-bis(heteroaryl)complexes and methods of use thereof |
| WO2010065906A2 (en) | 2008-12-05 | 2010-06-10 | Molecular Insight Pharmaceuticals, Inc. | Ca-ix specific radiopharmaceuticals for the treatment and imaging of cancer |
| TW201034691A (en) | 2008-12-05 | 2010-10-01 | Molecular Insight Pharm Inc | Technetium-and rhenium-bis(heteroaryl) complexes and methods of use thereof |
| EP2424868B1 (en) * | 2009-04-29 | 2018-01-10 | Nerviano Medical Sciences S.r.l. | Cdk inhibitor salts |
| AU2010260195B2 (en) | 2009-06-15 | 2014-11-20 | Molecular Insight Pharmaceuticals, Inc. | Process for production of heterodimers of glutamic acid |
| US20120263714A1 (en) * | 2009-10-21 | 2012-10-18 | Bayer Intellectual Property Gmbh | Substituted halophenoxybenzamide derivatives |
| US9125899B1 (en) | 2010-06-17 | 2015-09-08 | Stc.Unm | Modulators of GTPases and their use |
| WO2012021963A1 (en) * | 2010-07-09 | 2012-02-23 | Metasignal Therapeutics Inc. | Novel sulfonamide compounds for inhibition of metastatic tumor growth |
| EP2614065B1 (en) | 2010-12-17 | 2017-04-19 | Nerviano Medical Sciences S.r.l. | Substituted pyrazolo-quinazoline derivatives as kinase inhibitors |
| CN102351793B (zh) * | 2011-08-30 | 2013-11-06 | 江苏正大清江制药有限公司 | 4-[3-(4-甲基苯基)-5-(三氟甲基)-1-氢-吡唑-1-基]苯磺酰胺的直接合成方法 |
| BR112014006940A2 (pt) | 2011-09-23 | 2017-04-04 | Bayer Ip Gmbh | uso de derivados de ácido 1-fenilpirazol-3-carboxílico 4-substituído como agentes contra estresse abiótico em plantas |
| EP2800471A4 (en) | 2012-01-06 | 2015-11-04 | Molecular Insight Pharm Inc | METAL COMPLEX OF POLY (CARBOXYL) AMINE CONTAINING LIGANDS HAVING AFFINITY FOR CARBON IX ANHYDRASE |
| EP3300746B1 (en) | 2013-01-14 | 2019-05-15 | Molecular Insight Pharmaceuticals, Inc. | Triazine based radiopharmaceuticals and radioimaging agents |
| US10391119B2 (en) * | 2015-12-22 | 2019-08-27 | Nof Corporation | Lacrimal oily layer stabilizer and eye drops comprising same |
| WO2018211474A1 (en) | 2017-05-19 | 2018-11-22 | Trudell Medical International | Positive expiratory pressure device |
| USD903097S1 (en) | 2018-05-18 | 2020-11-24 | Trudell Medical International | Mask |
| USD874064S1 (en) | 2018-05-18 | 2020-01-28 | Trudell Medical International | Mask |
| USD893806S1 (en) | 2018-11-09 | 2020-08-18 | Trudell Medical Internationl | Mask and shroud |
| WO2020113094A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| CN109557309B (zh) * | 2018-12-04 | 2021-09-10 | 九江学院附属医院 | 碳酸酐酶-2作为检测标记物在肾结石诊断方面的应用 |
| CN111233786B (zh) * | 2020-02-04 | 2021-11-26 | 中国人民解放军军事科学院军事医学研究院 | 含五元杂环的苯磺酰胺类化合物及其制备方法和用途 |
| CN115607567A (zh) * | 2022-09-28 | 2023-01-17 | 长春工业大学 | 一种环保型改善心肌缺血的血液透析液 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1582619A (en) * | 1977-05-14 | 1981-01-14 | Centrala Ind Medicamente | Medicinal compositions for the treatment of gastritis gastro-duodenitis and duodenal ulcers |
| US5095026A (en) * | 1983-02-04 | 1992-03-10 | University Of Iowa Research Foundation | Prodrugs of carbonic anhydrase inhibitors |
| US5157044A (en) * | 1983-02-04 | 1992-10-20 | University Of Iowa Research Foundation | Analogs of carbonic anhydrase inhibitors and their use as topical IOP inhibitors |
| US4911920A (en) * | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
| DE69120430D1 (de) * | 1990-12-18 | 1996-07-25 | Wellcome Found | Mittel zur verstaerkung der wirkung von antitumoralen mittel und zur widerstandsbekaempfung von vielfachdrogen |
| AU653279B2 (en) * | 1991-12-30 | 1994-09-22 | Sanofi | Novel 2-saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof |
| US6090834A (en) * | 1993-05-21 | 2000-07-18 | G.D. Searle & Co. | Substituted oxazoles for the treatment of inflammation |
| US5466823A (en) * | 1993-11-30 | 1995-11-14 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides |
| ES2141916T3 (es) * | 1993-11-30 | 2000-04-01 | Searle & Co | Pirazolil-bencenosulfonamidas sustituidas para el tratamiento de la inflamacion. |
| US6369103B1 (en) * | 1994-01-18 | 2002-04-09 | Bristol-Myers Squibb Company | Method for preventing or reducing risk of onset of cardiovascular events employing an HMG CoA reductase inhibitor |
| US5547975A (en) * | 1994-09-20 | 1996-08-20 | Talley; John J. | Benzopyranopyrazolyl derivatives for the treatment of inflammation |
| JP3181190B2 (ja) * | 1994-12-20 | 2001-07-03 | 日本たばこ産業株式会社 | オキサゾール誘導体 |
| ES2183935T3 (es) * | 1995-02-13 | 2003-04-01 | Searle & Co | Isoxazoles sustituidos para el tratamiento de la inflamacion. |
| US5633272A (en) * | 1995-02-13 | 1997-05-27 | Talley; John J. | Substituted isoxazoles for the treatment of inflammation |
| US5944021A (en) * | 1995-06-07 | 1999-08-31 | Rodriguez; Victorio C. | Therapeutic use of a carbonic anhydrase enzyme inhibitor for the treatment of brain edema |
| DE19600721A1 (de) * | 1996-01-12 | 1997-07-17 | Hoechst Ag | Verwendung von Inhibitoren des Carboanhydratase (CAH) zum Herstellen eines Medikaments zur Behandlung von Krebs |
| ES2199348T4 (es) * | 1996-02-26 | 2010-10-19 | ADVANCED RESEARCH & TECHNOLOGY INSTITUTE | Uso de inhibidores de carbonico anhidrasa para el tratamiento del edema macular. |
| US6077850A (en) * | 1997-04-21 | 2000-06-20 | G.D. Searle & Co. | Substituted benzopyran analogs for the treatment of inflammation |
| CA2372912C (en) * | 1997-10-14 | 2008-12-02 | G.D. Searle & Co. | Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia |
| US5972986A (en) * | 1997-10-14 | 1999-10-26 | G.D. Searle & Co. | Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia |
| US6025353A (en) * | 1997-11-19 | 2000-02-15 | G.D. Searle & Co. | Method of using cyclooxygenase-2 inhibitors as anti-angiogenic agents |
| US5972684A (en) * | 1997-11-25 | 1999-10-26 | Incyte Pharmaceuticals, Inc. | Carbonic anhydrase VIII |
| ES2140354B1 (es) * | 1998-08-03 | 2000-11-01 | S A L V A T Lab Sa | Imidazo (1,2a) azinas sustituidas como inhibidores selectivos de la cox-2. |
| WO2000018741A2 (en) * | 1998-09-30 | 2000-04-06 | Fujisawa Pharmaceutical Co., Ltd. | Pyrazole compounds as cox-2 inhibitors |
| SE9803761D0 (sv) * | 1998-11-04 | 1998-11-04 | Synphora Ab | Method to avoid increased iridial pigmentation during prostaglandin treatment |
| US6664288B1 (en) * | 1999-04-14 | 2003-12-16 | Dana Farber Cancer Institute, Inc. | Method and composition for the treatment of cancer |
| US6465448B1 (en) * | 1999-08-13 | 2002-10-15 | Case Western Reserve University | Methoxyamine potentiation of temozolomide anti-cancer activity |
| US6323226B1 (en) * | 1999-10-19 | 2001-11-27 | Texas Heart Institute | Treatment of heart disease with cox-2 inhibitors |
| EP1274700B1 (en) * | 2000-01-03 | 2004-11-17 | Pharmacia Corporation | Dihydrobenzopyrans, dihydrobenzothiopyrans, and tetrahydroquinolines for the treatment of cox-2-mediated disorders |
| AU2001233286B2 (en) * | 2000-02-01 | 2006-04-06 | Cayman Chemical Company, Incorporated | Internal 1,15-lactones of fluprostenol and related prostaglandin F2alpha analogs and their use in the treatment of glaucoma and intraocular hypertension |
| US6448030B1 (en) * | 2000-02-18 | 2002-09-10 | University Of Nevada-Las Vegas | Method for predicting the efficacy of anti-cancer drugs |
| JP2002179657A (ja) * | 2000-05-26 | 2002-06-26 | Japan Tobacco Inc | 5−(4−アミノスルホニル−3−フルオロフェニル)−4−シクロヘキシル−2−メチルオキサゾールの結晶多形 |
| WO2001091856A2 (en) * | 2000-06-01 | 2001-12-06 | Pharmacia Corporation | Use of cox2 inhibitors for treating skin injury from exposure to ultraviolet radiation |
| PE20020146A1 (es) * | 2000-07-13 | 2002-03-31 | Upjohn Co | Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2) |
| WO2002005848A2 (en) * | 2000-07-13 | 2002-01-24 | Pharmacia Corporation | Use of cox-2 inhibitors in the treatment and prevention of ocular cox-2 mediated disorders |
| US20020035148A1 (en) * | 2000-07-20 | 2002-03-21 | Ryuji Ueno | Treatment of ocular hypertension |
| CA2419158A1 (en) * | 2000-08-11 | 2002-02-21 | Einar Stefansson | Method for the prevention and treatment of retinopathy |
| SE0004229D0 (sv) * | 2000-11-17 | 2000-11-17 | Aga Ab | Inhalation of nitric oxide |
| WO2003013655A2 (en) * | 2001-08-10 | 2003-02-20 | Pharmacia Corporation | Carbonic anhydrase inhibitors |
-
2002
- 2002-08-07 US US10/213,793 patent/US20030100594A1/en not_active Abandoned
-
2003
- 2003-02-14 CA CA002495516A patent/CA2495516A1/en not_active Abandoned
- 2003-02-14 BR BR0313282-0A patent/BR0313282A/pt not_active IP Right Cessation
- 2003-02-14 EP EP03784730A patent/EP1526869A1/en not_active Withdrawn
- 2003-02-14 AU AU2003225571A patent/AU2003225571A1/en not_active Abandoned
- 2003-02-14 MX MXPA05001496A patent/MXPA05001496A/es not_active Application Discontinuation
- 2003-02-14 AU AU2003213062A patent/AU2003213062A1/en not_active Abandoned
- 2003-02-14 MX MXPA05001497A patent/MXPA05001497A/es not_active Application Discontinuation
- 2003-02-14 JP JP2004527530A patent/JP2005539022A/ja not_active Withdrawn
- 2003-02-14 CA CA002495502A patent/CA2495502A1/en not_active Abandoned
- 2003-02-14 EP EP03709105A patent/EP1526895A2/en not_active Withdrawn
- 2003-02-14 WO PCT/US2003/004469 patent/WO2004014430A1/en not_active Ceased
- 2003-02-14 WO PCT/US2003/004494 patent/WO2004014352A2/en not_active Ceased
- 2003-02-14 PL PL03374994A patent/PL374994A1/xx unknown
- 2003-02-14 JP JP2004527531A patent/JP2005539023A/ja not_active Withdrawn
- 2003-02-14 CN CNA038218801A patent/CN1681557A/zh active Pending
- 2003-02-14 BR BR0313299-4A patent/BR0313299A/pt not_active IP Right Cessation
- 2003-02-14 KR KR1020057002072A patent/KR20050056189A/ko not_active Ceased
-
2004
- 2004-04-19 US US10/827,075 patent/US20040198781A1/en not_active Abandoned
-
2005
- 2005-02-03 IL IL16668505A patent/IL166685A0/xx unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2005539023A5 (https=) | ||
| ES2243978T3 (es) | Composiciones que comprenden un inhibidor de la ciclooxigenasa-2 y un antagonista del receptor de leucotrieno b4. | |
| US6342510B1 (en) | Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitors and a leukotriene B4 receptor antagonist | |
| ES2262156T3 (es) | Composicion que comprende un inhibidor de la ciclooxigenasa 2 y un inhibidor de la leucotrieno a4 hidrolasa. | |
| US6136839A (en) | Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor | |
| EP0888127B1 (en) | Combinations having immunosuppressive effects, containing cyclooxygenase-2-inhibitors and 5-lipoxygenase inhibitors | |
| ES2252448T3 (es) | Composicion parenteral reconstituible que contiene un inhibidor de la cox-2. | |
| CA2495502A1 (en) | Methods for treating carbonic anhydrase mediated disorders | |
| EP0880363B1 (en) | Combinations, having immunosuppressive effects, containing a cyclooxygenase-2 inhibitor and a leukotriene a 4 hydrolase inhibitor | |
| JP2004526765A5 (https=) | ||
| NZ500141A (en) | Method of using cyclooxygenase-2 inhibitors in the prevention of cardiovascular disorders | |
| US20030157061A1 (en) | Combinations of a cyclooxygenase-2 selective inhibitor and a TNFalpha antagonist and therapeutic uses therefor | |
| RU2004121147A (ru) | Применение ингибиторов сох-2 в сочетании с противовирусными агентами для лечения инфекции вируса папилломы | |
| US20030220376A1 (en) | Methods for treating carbonic anhydrase mediated disorders | |
| JP2005501850A5 (https=) | ||
| JP2005507871A5 (https=) | ||
| CA2414674A1 (en) | Use of cox-2 inhibitors in the treatment and prevention of ocular cox-2 mediated disorders | |
| US20020035156A1 (en) | Combination therapy in the prevention of cardiovascular disorders | |
| JP2005501083A5 (https=) | ||
| JP2008533109A (ja) | 利尿を促進するための複合治療 | |
| JP2005535657A5 (https=) | ||
| HK1093011A (en) | Compositions comprising a cyclooxygenase-2 inhibitor and a leukotriene b4 receptor antagonist |