JP2005533093A5 - - Google Patents
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- Publication number
- JP2005533093A5 JP2005533093A5 JP2004520629A JP2004520629A JP2005533093A5 JP 2005533093 A5 JP2005533093 A5 JP 2005533093A5 JP 2004520629 A JP2004520629 A JP 2004520629A JP 2004520629 A JP2004520629 A JP 2004520629A JP 2005533093 A5 JP2005533093 A5 JP 2005533093A5
- Authority
- JP
- Japan
- Prior art keywords
- vial
- kgy
- blown
- nitrogen
- sealed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 239000013078 crystal Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0216416.8 | 2002-07-15 | ||
| GBGB0216416.8A GB0216416D0 (en) | 2002-07-15 | 2002-07-15 | Organic compounds |
| PCT/EP2003/007619 WO2004006886A2 (en) | 2002-07-15 | 2003-07-14 | Injectable depot formulation comprising crystals of iloperidone |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010236087A Division JP5670698B2 (ja) | 2002-07-15 | 2010-10-21 | イロペリドンの結晶を含有する注射用デポ製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005533093A JP2005533093A (ja) | 2005-11-04 |
| JP2005533093A5 true JP2005533093A5 (https=) | 2006-08-24 |
| JP5392961B2 JP5392961B2 (ja) | 2014-01-22 |
Family
ID=9940486
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004520629A Expired - Lifetime JP5392961B2 (ja) | 2002-07-15 | 2003-07-14 | イロペリドンの結晶を含有する注射用デポ製剤 |
| JP2010236087A Expired - Lifetime JP5670698B2 (ja) | 2002-07-15 | 2010-10-21 | イロペリドンの結晶を含有する注射用デポ製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010236087A Expired - Lifetime JP5670698B2 (ja) | 2002-07-15 | 2010-10-21 | イロペリドンの結晶を含有する注射用デポ製剤 |
Country Status (15)
| Country | Link |
|---|---|
| US (5) | US20050250813A1 (https=) |
| EP (1) | EP1523335B1 (https=) |
| JP (2) | JP5392961B2 (https=) |
| AT (1) | ATE348635T1 (https=) |
| AU (1) | AU2003281154B2 (https=) |
| CA (1) | CA2492467C (https=) |
| CY (1) | CY1106305T1 (https=) |
| DE (1) | DE60310564T2 (https=) |
| DK (1) | DK1523335T3 (https=) |
| ES (1) | ES2279153T3 (https=) |
| GB (1) | GB0216416D0 (https=) |
| NZ (1) | NZ537598A (https=) |
| PT (1) | PT1523335E (https=) |
| WO (1) | WO2004006886A2 (https=) |
| ZA (1) | ZA200410323B (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2436439T3 (es) | 2001-10-30 | 2014-01-02 | Novartis Ag | Formulaciones de medicamento de liberación lenta de iloperidona con un polímero |
| GB0216416D0 (en) * | 2002-07-15 | 2002-08-21 | Novartis Ag | Organic compounds |
| ATE411797T2 (de) | 2003-10-23 | 2008-11-15 | Otsuka Pharma Co Ltd | Sterile injizierbare aripiprazol-formulierung mit kontrollierter freisetzung und verfahren |
| EP1799865B1 (en) | 2004-09-30 | 2012-06-06 | Vanda Pharmaceuticals Inc. | Methods for the administration of iloperidone |
| US20100063093A1 (en) | 2007-03-28 | 2010-03-11 | Curt Wolfgang | Methods for the administration of iloperidone |
| US20090306137A1 (en) | 2006-05-22 | 2009-12-10 | Wolfgang Curt D | Treatment for depressive disorders |
| US8198305B2 (en) | 2007-04-13 | 2012-06-12 | Concert Pharmaceuticals Inc. | 1,2-benzisoxazol-3-yl compounds |
| MY152789A (en) | 2007-07-31 | 2014-11-28 | Otsuka Pharma Co Ltd | Methods for producing aripiprazole suspension and freeze-dried formulation |
| EP2198048A2 (en) | 2007-09-10 | 2010-06-23 | Vanda Pharmaceuticals Inc. | Prediction of qt prolongation based on snp genotype |
| BRPI0820993A2 (pt) | 2007-12-13 | 2017-05-09 | Vanda Pharmaceuticals Inc | método e composição para tratar uma condição mediada por alfa adrenoceptor |
| SI2222300T1 (sl) | 2007-12-13 | 2014-11-28 | Vanda Pharmaceuticals Inc. | Postopek in sestavek za zdravljenje stanja, posredovanega z receptorjem serotonina |
| WO2010031497A1 (en) * | 2008-09-19 | 2010-03-25 | Miklos Vertessy | New process for the preparation of iloperidone |
| CN101822673B (zh) * | 2009-03-04 | 2013-09-18 | 北京德众万全药物技术开发有限公司 | 一种含有伊潘立酮的固体药物组合物 |
| US20120136050A1 (en) | 2009-07-16 | 2012-05-31 | Vanda Pharmaceuticals Inc. | Use of a melatonin agonist for the treatment of sleep disorders including primary insomnia |
| EP2479176B1 (en) * | 2009-09-19 | 2014-09-17 | Zhejiang Huahai Pharmaceutical Co., Ltd. | Method for preparation of iloperidone and crystallization method thereof |
| CN102030744B (zh) * | 2009-09-30 | 2013-04-17 | 天津药物研究院 | 伊潘立酮晶体、其制备方法及药物组合物 |
| WO2011055188A1 (en) * | 2009-11-05 | 2011-05-12 | Orchid Chemicals And Pharmaceuticals Limited | An improved process for the preparation of iloperidone |
| MX2012007365A (es) * | 2009-12-23 | 2012-08-15 | Lupin Ltd | Composiciones farmaceuticas de liberacion lenta de iloperidona. |
| CN102108081A (zh) * | 2009-12-25 | 2011-06-29 | 重庆医药工业研究院有限责任公司 | 伊潘立酮的新晶型及其制备方法 |
| LT2523669T (lt) | 2010-01-11 | 2017-04-25 | Inotek Pharmaceuticals Corporation | Akispūdžio mažinimo būdas, derinys ir rinkinys |
| PH12012501906A1 (en) | 2010-03-26 | 2013-01-14 | Inotek Pharmaceuticals Corp | Method of reducing intraocular pressure in humans using n6 -cyclopentyladenosine (cpa), cpa derivatives or prodrugs thereof |
| CN101822674B (zh) * | 2010-05-27 | 2015-03-11 | 北京德众万全医药科技有限公司 | 一种伊潘立酮药物组合物及其制备方法 |
| JP5893616B2 (ja) * | 2010-10-18 | 2016-03-23 | 大日本住友製薬株式会社 | 注射用徐放性製剤 |
| WO2012063269A2 (en) | 2010-11-12 | 2012-05-18 | Cadila Healthcare Limited | Process for preparing iloperidone |
| WO2012090138A1 (en) | 2010-12-27 | 2012-07-05 | Ranbaxy Laboratories Limited | Processes for the preparation of iloperidone |
| CN102680636A (zh) * | 2011-03-11 | 2012-09-19 | 天津药物研究院 | 一种伊潘立酮原料药及其中间体的质量控制方法 |
| US11918557B2 (en) | 2012-01-26 | 2024-03-05 | Vanda Pharmaceuticals Inc. | Treatment of circadian rhythm disorders |
| WO2013112951A2 (en) | 2012-01-26 | 2013-08-01 | Vanda Pharmaceuticals Inc. | Treatment of circadian rhythm disorders |
| PT2807178T (pt) | 2012-01-26 | 2017-08-08 | Inotek Pharmaceuticals Corp | Polimorfos anidros de nitrato de (2r,3s,4r,5r)-5-(6-(ciclopentilamino)-9h-purin-9-il)-3,4-dihidroxitetrahidrofuran-2-il)}metilo e seus processos de preparação |
| CN102659771B (zh) * | 2012-04-18 | 2013-11-27 | 吉林三善恩科技开发有限公司 | 一种伊潘立酮药物共晶及其制备方法 |
| CN102633786B (zh) * | 2012-04-18 | 2013-11-27 | 吉林三善恩科技开发有限公司 | 一种伊潘立酮药物共晶及其制备方法 |
| BR112014028446A2 (pt) | 2012-05-18 | 2017-10-24 | Vanda Pharmaceuticals Inc | composto isolado, composição farmacêutica, método de tratamento ou prevenção de pelo menos um de doenças, distúrbios ou condições seguintes, e, método de tratamento ou prevenção de um distúrbio de ritmo circadiano ou distúrbio com um componente circadiano em um indivíduo |
| KR102148990B1 (ko) | 2012-12-18 | 2020-08-27 | 반다 파마슈티칼즈, 인코퍼레이티드. | 일주기 리듬 장애의 치료 |
| NZ630759A (en) | 2013-03-15 | 2017-07-28 | Inotek Pharmaceuticals Corp | Ophthalmic formulations comprising an a1 agonist |
| US11090285B2 (en) | 2013-11-12 | 2021-08-17 | Vanda Pharmaceuticals Inc | Treatment of circadian rhythm disorders |
| US10376487B2 (en) | 2013-11-12 | 2019-08-13 | Vanda Pharmaceuticals Inc. | Method of treatment |
| CN103599074A (zh) * | 2013-11-26 | 2014-02-26 | 重庆医药工业研究院有限责任公司 | 一种伊潘立酮缓释微球及其制备方法 |
| WO2016134049A1 (en) | 2015-02-17 | 2016-08-25 | Vanda Pharmaceuticals Inc. | Iloperidone for the treatment of schizophrenia |
| US11071728B2 (en) | 2015-12-11 | 2021-07-27 | Vanda Pharmaceuticals Inc. | Treatment of schizophrenia |
| CN106831741B (zh) * | 2016-12-28 | 2019-08-23 | 北京医药集团有限责任公司 | 一种伊潘立酮超细粉体的制备方法 |
| US10935106B2 (en) * | 2018-06-14 | 2021-03-02 | Serapid, Inc. | Block chain with monolithic links |
| CN113164382A (zh) * | 2018-12-04 | 2021-07-23 | 万达制药公司 | 伊潘立酮的贮库施用 |
| US20200171018A1 (en) * | 2018-12-04 | 2020-06-04 | Vanda Pharmaceuticals Inc. | Depot administration of iloperidone |
| US11607408B2 (en) | 2019-10-15 | 2023-03-21 | Vanda Pharmaceuticals Inc. | Method of treatment of schizophrenia |
| WO2024137439A1 (en) | 2022-12-19 | 2024-06-27 | Vanda Pharmaceuticals Inc. | Dosage regime of iloperidone for treating bipolar i disorder and schizophrenia |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB216416A (en) | 1923-09-06 | 1924-05-29 | James Baker And Sons Ltd | Improvements in boots and shoes |
| IT1093097B (it) * | 1976-10-28 | 1985-07-19 | Hoechst France | Acidi n-carbetossi(alfa-amminofenilacetici)otticamente attivi relativo procedimento di produzione e loro impiego per la produzione di acidi alfa-ammino-fenilacetici otticamente attivi corrispondenti |
| CH656884A5 (de) | 1983-08-26 | 1986-07-31 | Sandoz Ag | Polyolester, deren herstellung und verwendung. |
| DE3345355A1 (de) * | 1983-12-15 | 1985-06-27 | Hoechst Ag, 6230 Frankfurt | Verfahren zur racematspaltung bicyclischer imino-(alpha)-carbonsaeureester |
| DE3511587A1 (de) | 1985-03-27 | 1986-10-02 | Schering AG, Berlin und Bergkamen, 1000 Berlin | Glykoester des estradiols und estriols |
| US4886370A (en) | 1987-08-25 | 1989-12-12 | Nkk Corporation | Method for detecting a state of substance existing in pipe |
| US5364866A (en) * | 1989-05-19 | 1994-11-15 | Hoechst-Roussel Pharmaceuticals, Inc. | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics |
| US5776963A (en) * | 1989-05-19 | 1998-07-07 | Hoechst Marion Roussel, Inc. | 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility |
| ES2076253T3 (es) * | 1989-05-19 | 1995-11-01 | Hoechst Roussel Pharma | N-(ariloxialquil)-heteroarilpiperidinas y -heteroarilpiperazinas, un procedimiento para su preparacion y su uso como medicamentos. |
| US5538739A (en) * | 1989-07-07 | 1996-07-23 | Sandoz Ltd. | Sustained release formulations of water soluble peptides |
| WO1991018927A1 (en) * | 1990-06-04 | 1991-12-12 | Schering Corporation | Method for preparing interferon alpha-2 crystals |
| CA2095499A1 (en) * | 1992-05-08 | 1993-11-09 | Petrus J. M. Van Den Oetelaar | Depot preparation |
| CA2148823C (en) | 1992-11-17 | 1999-03-09 | Welfide Corporation | Sustained release microsphere preparation containing antipsychotic drug and production process thereof |
| CN1074923C (zh) | 1993-11-19 | 2001-11-21 | 詹森药业有限公司 | 微囊密封的3-哌啶基取代的1,2-苯并异唑类和1,2-苯并异噻唑类 |
| US5902882A (en) * | 1996-04-17 | 1999-05-11 | Hoffmann-La Roche Inc. | Assymetric synthesis of azepines |
| TW487572B (en) * | 1996-05-20 | 2002-05-21 | Janssen Pharmaceutica Nv | Aqueous suspensions of 9-hydroxyrisperidone fatty acid esters |
| PL337027A1 (en) * | 1997-05-26 | 2000-07-31 | Akzo Nobel Nv | Salts of aromatic sulphonic acids |
| UA72189C2 (uk) * | 1997-11-17 | 2005-02-15 | Янссен Фармацевтика Н.В. | Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот |
| US5955459A (en) * | 1997-11-26 | 1999-09-21 | Neuromedica, Inc. | Fatty acid-antipsychotic compositions and uses thereof |
| US6541606B2 (en) * | 1997-12-31 | 2003-04-01 | Altus Biologics Inc. | Stabilized protein crystals formulations containing them and methods of making them |
| DE19816070A1 (de) | 1998-04-09 | 1999-10-14 | Aventis Res & Tech Gmbh & Co | Retardtablette hergestellt aus linearen wasserunlöslichen Polysacchariden |
| PL348107A1 (en) | 1998-10-16 | 2002-05-06 | Janssen Pharmaceutica Nv | Therapy for improving cognition |
| US6509310B1 (en) | 2000-06-01 | 2003-01-21 | Huish Detergents, Inc. | Compositions containing α-sulfofatty acid esters and method of making the same |
| AU2001263775A1 (en) | 2000-06-02 | 2001-12-11 | Novo-Nordisk A/S | Glucose dependent release of insulin from glucose sensing insulin derivatives |
| DK1425272T3 (da) * | 2001-08-31 | 2011-11-21 | Novartis Ag | Optiske isomerer af en iloperidon-metabolit |
| ES2436439T3 (es) * | 2001-10-30 | 2014-01-02 | Novartis Ag | Formulaciones de medicamento de liberación lenta de iloperidona con un polímero |
| GB0216416D0 (en) | 2002-07-15 | 2002-08-21 | Novartis Ag | Organic compounds |
-
2002
- 2002-07-15 GB GBGB0216416.8A patent/GB0216416D0/en not_active Ceased
-
2003
- 2003-07-14 AU AU2003281154A patent/AU2003281154B2/en not_active Expired
- 2003-07-14 WO PCT/EP2003/007619 patent/WO2004006886A2/en not_active Ceased
- 2003-07-14 EP EP03756455A patent/EP1523335B1/en not_active Expired - Lifetime
- 2003-07-14 PT PT03756455T patent/PT1523335E/pt unknown
- 2003-07-14 AT AT03756455T patent/ATE348635T1/de active
- 2003-07-14 CA CA2492467A patent/CA2492467C/en not_active Expired - Lifetime
- 2003-07-14 DE DE60310564T patent/DE60310564T2/de not_active Expired - Lifetime
- 2003-07-14 ES ES03756455T patent/ES2279153T3/es not_active Expired - Lifetime
- 2003-07-14 US US10/521,064 patent/US20050250813A1/en not_active Abandoned
- 2003-07-14 DK DK03756455T patent/DK1523335T3/da active
- 2003-07-14 NZ NZ537598A patent/NZ537598A/en not_active IP Right Cessation
- 2003-07-14 JP JP2004520629A patent/JP5392961B2/ja not_active Expired - Lifetime
-
2004
- 2004-12-22 ZA ZA200410323A patent/ZA200410323B/en unknown
-
2006
- 2006-12-29 CY CY20061101867T patent/CY1106305T1/el unknown
-
2008
- 2008-10-21 US US12/254,925 patent/US20090099232A1/en not_active Abandoned
-
2010
- 2010-10-21 JP JP2010236087A patent/JP5670698B2/ja not_active Expired - Lifetime
-
2011
- 2011-05-12 US US13/106,417 patent/US8293765B2/en not_active Expired - Fee Related
-
2012
- 2012-02-21 US US13/401,310 patent/US8227488B2/en not_active Expired - Fee Related
- 2012-09-14 US US13/618,753 patent/US8614232B2/en not_active Expired - Fee Related
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