JP2005532990A5 - - Google Patents
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- Publication number
- JP2005532990A5 JP2005532990A5 JP2003557494A JP2003557494A JP2005532990A5 JP 2005532990 A5 JP2005532990 A5 JP 2005532990A5 JP 2003557494 A JP2003557494 A JP 2003557494A JP 2003557494 A JP2003557494 A JP 2003557494A JP 2005532990 A5 JP2005532990 A5 JP 2005532990A5
- Authority
- JP
- Japan
- Prior art keywords
- aqueous solution
- nicotinamide
- cyclodextrin
- niacin
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/033,835 US6881726B2 (en) | 2001-12-24 | 2001-12-24 | Aqueous compositions containing metronidazole |
| PCT/US2002/036063 WO2003057135A2 (en) | 2001-12-24 | 2002-11-07 | Aqueous compositions containing metronidazole |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005532990A JP2005532990A (ja) | 2005-11-04 |
| JP2005532990A5 true JP2005532990A5 (https=) | 2006-01-05 |
| JP4611632B2 JP4611632B2 (ja) | 2011-01-12 |
Family
ID=21872727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003557494A Expired - Lifetime JP4611632B2 (ja) | 2001-12-24 | 2002-11-07 | メトロニダゾールを含む水性組成物 |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US6881726B2 (https=) |
| EP (3) | EP1467744B1 (https=) |
| JP (1) | JP4611632B2 (https=) |
| KR (1) | KR100718858B1 (https=) |
| CN (1) | CN100411624C (https=) |
| AR (1) | AR037755A1 (https=) |
| AT (1) | ATE481105T1 (https=) |
| AU (1) | AU2002340458B2 (https=) |
| BR (1) | BRPI0215331B8 (https=) |
| CA (1) | CA2470492C (https=) |
| CY (1) | CY1111095T1 (https=) |
| DE (1) | DE60237710D1 (https=) |
| DK (1) | DK1467744T3 (https=) |
| ES (1) | ES2352656T3 (https=) |
| MX (1) | MXPA04006210A (https=) |
| PT (1) | PT1467744E (https=) |
| RU (2) | RU2284810C2 (https=) |
| WO (1) | WO2003057135A2 (https=) |
| ZA (1) | ZA200405059B (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6468989B1 (en) * | 2000-07-13 | 2002-10-22 | Dow Pharmaceutical Sciences | Gel compositions containing metronidazole |
| DE10306453A1 (de) * | 2003-02-17 | 2004-08-26 | Deutsche Telekom Ag | Administrator |
| US7456207B2 (en) * | 2003-09-25 | 2008-11-25 | Teva Pharmaceuticals Usa, Inc. | Vaginal pharmaceutical compositions and methods for preparing them |
| FR2866566A1 (fr) * | 2004-02-20 | 2005-08-26 | Galderma Res & Dev | Utilisation d'un inhibiteur de la secretion d'il-5,il-6 et/ou il-10 pour le traitement de la rosacee |
| FR2887149B1 (fr) * | 2005-06-17 | 2007-08-03 | Galderma Sa | Procede de solubilisation du metronidazole |
| US20060093675A1 (en) * | 2004-10-29 | 2006-05-04 | Mathew Ebmeier | Intravaginal treatment of vaginal infections with metronidazole compositions |
| DE602006020063D1 (de) * | 2005-12-07 | 2011-03-24 | Univ Ramot | Wirkstoffabgebende verbundkörper |
| ES2439582T3 (es) * | 2007-03-12 | 2014-01-23 | Dsm Ip Assets B.V. | Composiciones cosméticas |
| US20080287514A1 (en) * | 2007-05-14 | 2008-11-20 | Jerry Zhang | Topical compositions containing metronidazole |
| US20080287513A1 (en) * | 2007-05-14 | 2008-11-20 | Jerry Zhang | Topical compositions containing metronidazole |
| US20080312304A1 (en) * | 2007-06-13 | 2008-12-18 | Jerry Zhang | Topical compositions containing metronidazole |
| JP4456177B2 (ja) * | 2007-09-04 | 2010-04-28 | 明治製菓株式会社 | 注射剤、注射液および注射用キット製剤 |
| AR061947A1 (es) * | 2008-01-08 | 2008-08-10 | Oscar Belluscio Daniel | Metodo para la obtencion del complejo gonadotrofina corionica humana (gch) / ciclodextrina administrable por via oral, producto obtenido con dicho metodo y uso clinico-terapeutico del complejo gonadotrofina corionica humana (gch) / ciclodextrina |
| US7893097B2 (en) | 2008-02-02 | 2011-02-22 | Dow Pharmaceutical Sciences, Inc. | Methods and compositions for increasing solubility of azole drug compounds that are poorly soluble in water |
| EP2303353B1 (en) * | 2008-06-12 | 2018-01-10 | Ramot at Tel-Aviv University Ltd. | Drug-eluting medical devices |
| US8729108B2 (en) * | 2008-06-17 | 2014-05-20 | Christopher J Dannaker | Waterborne topical compositions for the delivery of active ingredients such as azelaic acid |
| US20100105750A1 (en) * | 2008-10-23 | 2010-04-29 | Nycomed Us Inc. | Stable metronidazole gel formulations |
| EP2201930A1 (en) | 2008-12-23 | 2010-06-30 | Intendis GmbH | Hydrogel composition for the treatment of dermatological disorders |
| EP2419138A4 (en) * | 2009-04-14 | 2013-08-21 | Medortus Uk Ltd | GEL COMPOSITIONS FOR THE ADMINISTRATION OF PHARMACEUTICALLY ACTIVE COMPOUNDS |
| US20120171184A1 (en) | 2010-12-31 | 2012-07-05 | Lajos Szente | Cellular hydration compositions |
| CN105903028B (zh) * | 2010-12-31 | 2020-10-16 | 东塘实验室有限公司 | 含有环糊精的细胞水合组合物 |
| AU2010366535A1 (en) * | 2010-12-31 | 2013-07-11 | Eastpond Laboratories Limited | Cellular hydration compositions containing cyclodextrins |
| JP5864615B2 (ja) | 2011-01-25 | 2016-02-17 | ザ プロクター アンド ギャンブルカンパニー | リポソーム及びそれを含むパーソナルケア組成物 |
| JP5986632B2 (ja) | 2011-06-28 | 2016-09-06 | メディシス ファーマシューティカル コーポレイション | 高用量粘膜接着性メトロニダゾール水系ゲル製剤および細菌性膣炎を治療するためのそれらの使用 |
| US9511144B2 (en) | 2013-03-14 | 2016-12-06 | The Proctor & Gamble Company | Cosmetic compositions and methods providing enhanced penetration of skin care actives |
| EP2952208A1 (en) * | 2014-06-04 | 2015-12-09 | Universidade de Santiago de Compostela | Hydroalcoholic system for nail treatment |
| US20170232024A1 (en) | 2014-08-04 | 2017-08-17 | Jerry Tan Eye Surgery Pte Ltd | Pharmaceutical compositions for demodex related blepharitis and eyelid crusting |
| JP2015044850A (ja) * | 2014-11-07 | 2015-03-12 | イーストポンド・ラボラトリーズ・リミテッド | シクロデキストリンを含有する細胞水和組成物 |
| US9492374B2 (en) * | 2015-03-25 | 2016-11-15 | Jose Rafael Salinas Andrade | Composition and method for treatment of ulcers |
| WO2019118928A1 (en) | 2017-12-15 | 2019-06-20 | Tarsus Pharmaceuticals, Inc. | Isoxazoline parasiticide formulations and methods for treating blepharitis |
| US11198831B2 (en) | 2019-01-31 | 2021-12-14 | Kvi Llc | Lubricant for a device |
| US12502377B2 (en) | 2019-04-04 | 2025-12-23 | Tarsus Pharmaceuticals, Inc. | Method of eradicating ticks that attach to humans using lotilaner formulations |
| CN111840632A (zh) * | 2019-04-25 | 2020-10-30 | 广东泰宝医疗科技股份有限公司 | 一种含止血微囊的液体敷料及其制备方法 |
| EP4157290A4 (en) * | 2020-06-02 | 2024-06-05 | National University of Singapore | COMPOSITIONS, THEIR USES IN THERAPY AND METHODS THEREFOR |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4032645A (en) * | 1975-06-19 | 1977-06-28 | G. D. Searle & Co. | Injectable metronidazole composition |
| US4267169A (en) * | 1978-07-22 | 1981-05-12 | Toko Yakuhin Kogyo Kabushiki Kaisha | Novel preparation of clotrimazole |
| GB8330969D0 (en) * | 1983-11-21 | 1983-12-29 | Wellcome Found | Promoting healing |
| DE3346123A1 (de) | 1983-12-21 | 1985-06-27 | Janssen Pharmaceutica, N.V., Beerse | Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung |
| US4596795A (en) | 1984-04-25 | 1986-06-24 | The United States Of America As Represented By The Secretary, Dept. Of Health & Human Services | Administration of sex hormones in the form of hydrophilic cyclodextrin derivatives |
| US4727064A (en) | 1984-04-25 | 1988-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Pharmaceutical preparations containing cyclodextrin derivatives |
| US4837378A (en) | 1986-01-15 | 1989-06-06 | Curatek Pharmaceuticals, Inc. | Topical metronidazole formulations and therapeutic uses thereof |
| US5002935A (en) * | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
| US5536743A (en) | 1988-01-15 | 1996-07-16 | Curatek Pharmaceuticals Limited Partnership | Intravaginal treatment of vaginal infections with buffered metronidazole compositions |
| EP0335545B2 (en) | 1988-03-29 | 1998-09-23 | University Of Florida | Pharmaceutical formulations for parenteral use |
| US5997856A (en) | 1988-10-05 | 1999-12-07 | Chiron Corporation | Method and compositions for solubilization and stabilization of polypeptides, especially proteins |
| RU2029548C1 (ru) * | 1989-07-07 | 1995-02-27 | Центр по химии лекарственных средств | Антимикробное или радиосенсибилизирующее средство |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| TW200402B (https=) | 1990-08-13 | 1993-02-21 | Senju Pharma Co | |
| DE69232535D1 (de) | 1991-06-24 | 2002-05-08 | Pacific Biomedical Res Inc | In langzeitkultur gehaltene hormon-absondernde pankreatische zellen |
| US5747341A (en) | 1991-06-24 | 1998-05-05 | Pacific Biomedical Research, Inc. | Culture media having low osmolarity for establishing and maintaining hormone-secreting cells in long-term culture |
| US5324718A (en) * | 1992-07-14 | 1994-06-28 | Thorsteinn Loftsson | Cyclodextrin/drug complexation |
| US5472954A (en) | 1992-07-14 | 1995-12-05 | Cyclops H.F. | Cyclodextrin complexation |
| US5646131A (en) * | 1994-02-22 | 1997-07-08 | The Arab Company For Drug Industries And Medical Applicances (Acdima) | Method for solubilizing drugs using cyclodextrins and carboxylic acids |
| ZA952521B (en) * | 1994-03-28 | 1996-03-15 | Univ Columbia | Composition for inactivating irritants in fluids |
| FR2722098B1 (fr) | 1994-07-06 | 1996-08-23 | Cird Galderma | Nouveaux medicaments a base de metro-nidazole ou d'un melange synergetique de metronidazole et de clindamycine |
| US5874418A (en) * | 1997-05-05 | 1999-02-23 | Cydex, Inc. | Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use |
| AU750125B2 (en) * | 1997-08-27 | 2002-07-11 | Hexal Ag | New pharmaceutical compositions of meloxicam with improved solubility and bioavailability |
| US6017516A (en) * | 1997-10-31 | 2000-01-25 | Lekar Pharma Limited | Pharmaceutical dental formulation for topical application of metronidazole benzoate and chlorhexidine gluconate |
| US6183766B1 (en) | 1999-02-12 | 2001-02-06 | The Procter & Gamble Company | Skin sanitizing compositions |
| US6468989B1 (en) * | 2000-07-13 | 2002-10-22 | Dow Pharmaceutical Sciences | Gel compositions containing metronidazole |
| CN1116038C (zh) * | 2000-11-18 | 2003-07-30 | 雷文彬 | 一种治疗痤疮的外用药液 |
-
2001
- 2001-12-24 US US10/033,835 patent/US6881726B2/en not_active Expired - Lifetime
-
2002
- 2002-11-07 MX MXPA04006210A patent/MXPA04006210A/es active IP Right Grant
- 2002-11-07 RU RU2004122696/15A patent/RU2284810C2/ru active
- 2002-11-07 DE DE60237710T patent/DE60237710D1/de not_active Expired - Lifetime
- 2002-11-07 WO PCT/US2002/036063 patent/WO2003057135A2/en not_active Ceased
- 2002-11-07 EP EP02778822A patent/EP1467744B1/en not_active Expired - Lifetime
- 2002-11-07 PT PT02778822T patent/PT1467744E/pt unknown
- 2002-11-07 EP EP10170958A patent/EP2238980A1/en not_active Ceased
- 2002-11-07 JP JP2003557494A patent/JP4611632B2/ja not_active Expired - Lifetime
- 2002-11-07 KR KR1020047010051A patent/KR100718858B1/ko not_active Expired - Lifetime
- 2002-11-07 EP EP10170977A patent/EP2241320A1/en not_active Withdrawn
- 2002-11-07 BR BRPI0215331A patent/BRPI0215331B8/pt not_active IP Right Cessation
- 2002-11-07 AT AT02778822T patent/ATE481105T1/de active
- 2002-11-07 CA CA2470492A patent/CA2470492C/en not_active Expired - Fee Related
- 2002-11-07 AU AU2002340458A patent/AU2002340458B2/en not_active Expired
- 2002-11-07 ES ES02778822T patent/ES2352656T3/es not_active Expired - Lifetime
- 2002-11-07 DK DK02778822.3T patent/DK1467744T3/da active
- 2002-11-07 CN CNB028283163A patent/CN100411624C/zh not_active Expired - Fee Related
- 2002-12-09 AR ARP020104758A patent/AR037755A1/es not_active Application Discontinuation
-
2004
- 2004-06-25 ZA ZA2004/05059A patent/ZA200405059B/en unknown
-
2005
- 2005-01-18 US US11/037,430 patent/US7348317B2/en not_active Expired - Lifetime
-
2006
- 2006-05-11 RU RU2006116252/15A patent/RU2413501C2/ru active
-
2008
- 2008-02-27 US US12/072,578 patent/US20080154030A1/en not_active Abandoned
-
2009
- 2009-10-27 US US12/589,680 patent/US20100048659A1/en not_active Abandoned
-
2010
- 2010-11-11 CY CY20101101017T patent/CY1111095T1/el unknown
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