JP2019131596A5 - - Google Patents
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- Publication number
- JP2019131596A5 JP2019131596A5 JP2019074133A JP2019074133A JP2019131596A5 JP 2019131596 A5 JP2019131596 A5 JP 2019131596A5 JP 2019074133 A JP2019074133 A JP 2019074133A JP 2019074133 A JP2019074133 A JP 2019074133A JP 2019131596 A5 JP2019131596 A5 JP 2019131596A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- solid oral
- meloxicam
- oral pharmaceutical
- sbeβcd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007787 solid Substances 0.000 claims 15
- 239000008203 oral pharmaceutical composition Substances 0.000 claims 14
- ZRVUJXDFFKFLMG-UHFFFAOYSA-N Meloxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=NC=C(C)S1 ZRVUJXDFFKFLMG-UHFFFAOYSA-N 0.000 claims 11
- 229960001929 meloxicam Drugs 0.000 claims 11
- 229920000858 Cyclodextrin Polymers 0.000 claims 2
- 238000004090 dissolution Methods 0.000 claims 2
- SUBDBMMJDZJVOS-DEOSSOPVSA-N esomeprazole Chemical group C([S@](=O)C1=NC2=CC=C(C=C2N1)OC)C1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-DEOSSOPVSA-N 0.000 claims 2
- 229960004770 esomeprazole Drugs 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 229940126409 proton pump inhibitor Drugs 0.000 claims 2
- 239000000612 proton pump inhibitor Substances 0.000 claims 2
- NZAQRZWBQUIBSF-UHFFFAOYSA-N 4-(4-sulfobutoxy)butane-1-sulfonic acid Chemical group OS(=O)(=O)CCCCOCCCCS(O)(=O)=O NZAQRZWBQUIBSF-UHFFFAOYSA-N 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
- 239000001116 FEMA 4028 Substances 0.000 claims 1
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims 1
- 235000011175 beta-cyclodextrine Nutrition 0.000 claims 1
- 229960004853 betadex Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000002496 gastric effect Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 claims 1
- 229940097346 sulfobutylether-beta-cyclodextrin Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562259993P | 2015-11-25 | 2015-11-25 | |
| US62/259,993 | 2015-11-25 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017560488A Division JP6746612B2 (ja) | 2015-11-25 | 2016-04-11 | メロキシカムを含む医薬組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021016747A Division JP7017275B2 (ja) | 2015-11-25 | 2021-02-04 | メロキシカムを含む固体医薬組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019131596A JP2019131596A (ja) | 2019-08-08 |
| JP2019131596A5 true JP2019131596A5 (https=) | 2019-10-17 |
| JP6842122B2 JP6842122B2 (ja) | 2021-03-17 |
Family
ID=60389519
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017560488A Active JP6746612B2 (ja) | 2015-11-25 | 2016-04-11 | メロキシカムを含む医薬組成物 |
| JP2019074133A Active JP6842122B2 (ja) | 2015-11-25 | 2019-04-09 | メロキシカムを含む医薬組成物 |
| JP2021016747A Active JP7017275B2 (ja) | 2015-11-25 | 2021-02-04 | メロキシカムを含む固体医薬組成物 |
| JP2022007214A Active JP7332202B2 (ja) | 2015-11-25 | 2022-01-20 | メロキシカムを含む固体医薬組成物 |
| JP2023126893A Active JP7721602B2 (ja) | 2015-11-25 | 2023-08-03 | メロキシカムを含む固体医薬組成物 |
| JP2025127530A Pending JP2025142338A (ja) | 2015-11-25 | 2025-07-30 | メロキシカムを含む固体医薬組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017560488A Active JP6746612B2 (ja) | 2015-11-25 | 2016-04-11 | メロキシカムを含む医薬組成物 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021016747A Active JP7017275B2 (ja) | 2015-11-25 | 2021-02-04 | メロキシカムを含む固体医薬組成物 |
| JP2022007214A Active JP7332202B2 (ja) | 2015-11-25 | 2022-01-20 | メロキシカムを含む固体医薬組成物 |
| JP2023126893A Active JP7721602B2 (ja) | 2015-11-25 | 2023-08-03 | メロキシカムを含む固体医薬組成物 |
| JP2025127530A Pending JP2025142338A (ja) | 2015-11-25 | 2025-07-30 | メロキシカムを含む固体医薬組成物 |
Country Status (22)
| Country | Link |
|---|---|
| EP (3) | EP3256138B1 (https=) |
| JP (6) | JP6746612B2 (https=) |
| KR (9) | KR102465027B1 (https=) |
| CN (2) | CN113144218A (https=) |
| AU (4) | AU2016218992C1 (https=) |
| CA (4) | CA2976272C (https=) |
| CY (1) | CY1125193T1 (https=) |
| DK (1) | DK3256138T3 (https=) |
| ES (1) | ES2913288T3 (https=) |
| HU (1) | HUE058677T2 (https=) |
| IL (3) | IL316648A (https=) |
| LT (1) | LT3256138T (https=) |
| MX (2) | MX380762B (https=) |
| MY (1) | MY191574A (https=) |
| NZ (1) | NZ734233A (https=) |
| PL (1) | PL3256138T3 (https=) |
| PT (1) | PT3256138T (https=) |
| RS (1) | RS63260B1 (https=) |
| SG (2) | SG10202010157VA (https=) |
| SI (1) | SI3256138T1 (https=) |
| SM (1) | SMT202200194T1 (https=) |
| WO (1) | WO2016131067A2 (https=) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10729774B1 (en) | 2015-02-10 | 2020-08-04 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11013805B2 (en) | 2015-02-10 | 2021-05-25 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10537642B1 (en) | 2015-02-10 | 2020-01-21 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10933137B2 (en) | 2015-02-10 | 2021-03-02 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11602563B2 (en) | 2015-02-10 | 2023-03-14 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10780165B2 (en) | 2015-02-10 | 2020-09-22 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10702602B2 (en) | 2015-02-10 | 2020-07-07 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US9821075B2 (en) | 2015-02-10 | 2017-11-21 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10532101B1 (en) | 2015-02-10 | 2020-01-14 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10695430B2 (en) | 2015-02-10 | 2020-06-30 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10517950B1 (en) | 2015-02-10 | 2019-12-31 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10758618B2 (en) | 2015-02-10 | 2020-09-01 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11607456B2 (en) | 2015-02-10 | 2023-03-21 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10729773B2 (en) | 2015-02-10 | 2020-08-04 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10821181B2 (en) | 2015-02-10 | 2020-11-03 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US12485176B2 (en) | 2015-02-10 | 2025-12-02 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10722583B2 (en) | 2015-02-10 | 2020-07-28 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10933136B2 (en) | 2015-02-10 | 2021-03-02 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10653777B2 (en) | 2015-02-10 | 2020-05-19 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11110173B2 (en) | 2015-02-10 | 2021-09-07 | Axsome Therapeutics, Inc | Pharmaceutical compositions comprising meloxicam |
| US10695429B2 (en) | 2015-02-10 | 2020-06-30 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10512692B2 (en) | 2015-02-10 | 2019-12-24 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11045549B2 (en) | 2015-02-10 | 2021-06-29 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10780166B2 (en) | 2015-02-10 | 2020-09-22 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10799588B2 (en) | 2015-02-10 | 2020-10-13 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10058614B2 (en) | 2015-02-10 | 2018-08-28 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11738085B2 (en) | 2015-02-10 | 2023-08-29 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11013806B2 (en) | 2015-02-10 | 2021-05-25 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| CN113144218A (zh) * | 2015-11-25 | 2021-07-23 | 艾克萨姆治疗公司 | 包含美洛昔康的药物组合物 |
| US11207327B2 (en) | 2017-01-04 | 2021-12-28 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11471465B2 (en) | 2017-01-04 | 2022-10-18 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| KR102627411B1 (ko) * | 2017-01-04 | 2024-01-18 | 액섬 테라퓨틱스, 인크. | 멜록시캄을 포함하는 약학적 조성물 |
| US10894053B2 (en) | 2017-01-04 | 2021-01-19 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
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| US11801250B2 (en) | 2017-01-04 | 2023-10-31 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11433079B2 (en) | 2017-01-04 | 2022-09-06 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10583144B2 (en) | 2017-01-04 | 2020-03-10 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10729696B2 (en) | 2017-01-04 | 2020-08-04 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10905693B2 (en) | 2017-01-04 | 2021-02-02 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11806354B2 (en) | 2017-01-04 | 2023-11-07 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10561664B1 (en) | 2017-01-04 | 2020-02-18 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10940153B2 (en) | 2017-01-04 | 2021-03-09 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10471014B2 (en) | 2017-01-04 | 2019-11-12 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11433078B2 (en) | 2017-01-04 | 2022-09-06 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10821182B2 (en) | 2017-06-29 | 2020-11-03 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| EP4650374A3 (en) * | 2017-05-10 | 2026-03-04 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
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| US10987358B2 (en) | 2017-06-29 | 2021-04-27 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10688102B2 (en) | 2017-06-29 | 2020-06-23 | Axsome Therapeutics, Inc. | Combination treatment for migraine and other pain |
| US11219626B2 (en) | 2017-06-29 | 2022-01-11 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10512693B2 (en) | 2017-06-29 | 2019-12-24 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10918722B2 (en) | 2017-06-29 | 2021-02-16 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11617756B2 (en) | 2017-06-29 | 2023-04-04 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11617791B2 (en) | 2017-06-29 | 2023-04-04 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10688185B2 (en) | 2017-06-29 | 2020-06-23 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11865117B2 (en) | 2017-06-29 | 2024-01-09 | Axsome Therapeutics, Inc | Pharmaceutical compositions comprising meloxicam |
| US11185550B2 (en) | 2017-06-29 | 2021-11-30 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US11510927B2 (en) | 2017-06-29 | 2022-11-29 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US10758617B2 (en) | 2017-06-29 | 2020-09-01 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| KR102006777B1 (ko) | 2018-01-29 | 2019-10-08 | 주식회사 종근당 | 에스오메프라졸 및 탄산수소나트륨을 포함하는 약제학적 제제 |
| KR102080023B1 (ko) | 2018-01-29 | 2020-02-21 | 주식회사 종근당 | 에스오메프라졸 및 탄산수소나트륨을 포함하는 안정한 약제학적 조성물 |
| SG11202012376PA (en) * | 2018-07-03 | 2021-01-28 | Axsome Therapeutics Inc | Pharmaceutical compositions comprising meloxicam |
| KR102146395B1 (ko) | 2018-08-23 | 2020-08-20 | 주식회사 종근당 | 에스오메프라졸 및 탄산수소나트륨을 포함하는 우수한 방출특성을 갖는 약제학적 제제 |
| US20230285306A1 (en) * | 2018-09-28 | 2023-09-14 | Axsome Therapeutics, Inc. | Dosage forms comprising active pharmaceutical ingredients |
| JP7237386B2 (ja) * | 2019-02-06 | 2023-03-13 | アクスサム セラピューティクス インコーポレイテッド | メロキシカムおよびリザトリプタンを含有する組み合わせの使用 |
| BR112022001287A2 (pt) * | 2019-07-26 | 2022-04-12 | Chong Kun Dang Pharmaceutical Corp | Composição farmacêutica |
| US20240058354A1 (en) | 2020-04-06 | 2024-02-22 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US12128052B2 (en) | 2020-05-28 | 2024-10-29 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US20250352478A1 (en) * | 2020-11-06 | 2025-11-20 | Mylan Laboratories Ltd | Pharmaceutical composition comprising meloxicam |
| US20250352552A1 (en) * | 2020-11-06 | 2025-11-20 | Mylan Laboratories Ltd | Pharmaceutical composition comprising meloxicam |
| WO2022097024A1 (en) * | 2020-11-06 | 2022-05-12 | Mylan Laboratories Ltd | Pharmaceutical composition comprising meloxicam |
| JP7495340B2 (ja) * | 2020-12-16 | 2024-06-04 | 株式会社ファンケル | カルノシン酸含有固体組成物及びカルノシン酸の溶出促進方法 |
| US12370196B2 (en) | 2020-12-31 | 2025-07-29 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| WO2022147155A1 (en) | 2020-12-31 | 2022-07-07 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| EP4331588A4 (en) * | 2021-04-27 | 2025-01-15 | Animuscure Inc. | COMPOSITION FOR THE PREVENTION OR TREATMENT OF MUSCLE DISEASES WITH AN OXICAM-BASED COMPOUND |
| US12005118B2 (en) | 2022-05-19 | 2024-06-11 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
| US12544383B1 (en) | 2025-01-30 | 2026-02-10 | Axsome Therapeutics, Inc. | Methods of treating migraines with a combination of a meloxicam and a rizatriptan |
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| WO2014161131A1 (en) * | 2013-04-01 | 2014-10-09 | Arissa Pharma | PREPARING AMORPHOUS MELOXICAM-β-CYCLODEXTRIN INCLUSION COMPLEX VIA SPRAY DRYING PROCESS |
| CN113144218A (zh) * | 2015-11-25 | 2021-07-23 | 艾克萨姆治疗公司 | 包含美洛昔康的药物组合物 |
-
2016
- 2016-04-11 CN CN202110356434.5A patent/CN113144218A/zh active Pending
- 2016-04-11 SG SG10202010157VA patent/SG10202010157VA/en unknown
- 2016-04-11 RS RS20220441A patent/RS63260B1/sr unknown
- 2016-04-11 ES ES16750078T patent/ES2913288T3/es active Active
- 2016-04-11 KR KR1020227024833A patent/KR102465027B1/ko active Active
- 2016-04-11 CN CN201680009582.7A patent/CN107405359B/zh active Active
- 2016-04-11 IL IL316648A patent/IL316648A/en unknown
- 2016-04-11 KR KR1020227038441A patent/KR102507663B1/ko active Active
- 2016-04-11 CA CA2976272A patent/CA2976272C/en active Active
- 2016-04-11 HU HUE16750078A patent/HUE058677T2/hu unknown
- 2016-04-11 JP JP2017560488A patent/JP6746612B2/ja active Active
- 2016-04-11 EP EP16750078.4A patent/EP3256138B1/en active Active
- 2016-04-11 KR KR1020217027341A patent/KR102429352B1/ko active Active
- 2016-04-11 DK DK16750078.4T patent/DK3256138T3/da active
- 2016-04-11 MX MX2017010304A patent/MX380762B/es unknown
- 2016-04-11 EP EP22151689.1A patent/EP4008319B1/en active Active
- 2016-04-11 KR KR1020237021609A patent/KR102827626B1/ko active Active
- 2016-04-11 LT LTEPPCT/US2016/026991T patent/LT3256138T/lt unknown
- 2016-04-11 SG SG11201706123XA patent/SG11201706123XA/en unknown
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