|
US7238707B2
(en)
|
2000-07-28 |
2007-07-03 |
Schering Ag |
Substituted pentanols, a process for their production and their use as anti-inflammatory agents
|
|
DE10346940B3
(de)
*
|
2003-10-06 |
2005-06-16 |
Schering Ag |
Substituierte Pentanole, ihre Verwendung zur Herstellung von Arzneimitteln speziell Entzündungshemmer sowie diese enthaltende pharmazeutische Präparate
|
|
CA2478156C
(en)
|
2002-03-26 |
2011-02-15 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
TWI328009B
(en)
|
2003-05-21 |
2010-08-01 |
Glaxo Group Ltd |
Quinoline derivatives as phosphodiesterase inhibitors
|
|
EA200600148A1
(ru)
*
|
2003-07-01 |
2006-08-25 |
Шеринг Акциенгезельшафт |
Гетероциклически замещённые производные пентанола, способ их получения и их применение в качестве ингибиторов воспаления
|
|
GB0316290D0
(en)
|
2003-07-11 |
2003-08-13 |
Glaxo Group Ltd |
Novel compounds
|
|
UY28526A1
(es)
|
2003-09-24 |
2005-04-29 |
Boehringer Ingelheim Pharma |
Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos
|
|
US7662821B2
(en)
|
2003-10-08 |
2010-02-16 |
Bayer Schering Pharma Ag |
Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
|
|
US7638515B2
(en)
|
2003-10-08 |
2009-12-29 |
Bayer Schering Pharma Aktiengesellschaft |
Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
|
|
PT1670458E
(pt)
|
2003-10-08 |
2007-03-30 |
Schering Ag |
Derivados de tetra-hidronaftaleno, processo para a sua preparação e utilização como inibidor de inflamação
|
|
US7507843B2
(en)
|
2003-10-16 |
2009-03-24 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Stereoselective synthesis of certain trifluoromethyl-substituted alcohols
|
|
US7795272B2
(en)
|
2004-03-13 |
2010-09-14 |
Boehringer Ingelheim Pharmaceutical, Inc. |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
|
|
US20080153859A1
(en)
|
2004-04-05 |
2008-06-26 |
Hartmut Rehwinkel |
Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
|
|
PE20060272A1
(es)
|
2004-05-24 |
2006-05-22 |
Glaxo Group Ltd |
(2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a
|
|
TWI307630B
(en)
|
2004-07-01 |
2009-03-21 |
Glaxo Group Ltd |
Immunoglobulins
|
|
GB0418045D0
(en)
*
|
2004-08-12 |
2004-09-15 |
Glaxo Group Ltd |
Compounds
|
|
DE102004044680B3
(de)
*
|
2004-09-09 |
2006-06-08 |
Schering Ag |
Alkyliden-Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer sowie diese enthaltende pharmazeutische Präparate
|
|
DE102005020331A1
(de)
*
|
2005-04-26 |
2006-11-02 |
Schering Ag |
5-substituierte Chinolin- und Isochinolin-Derivate, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
|
|
DE102004055633A1
(de)
*
|
2004-11-12 |
2006-05-18 |
Schering Ag |
5-substituierte Chinolin- und Isochinolin-Derivate, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
|
|
US7417056B2
(en)
|
2004-11-12 |
2008-08-26 |
Schering Ag |
5-substituted quinoline and isoquinoline derivatives, a process for their production and their use as anti-inflammatory agents
|
|
DE102004063227A1
(de)
*
|
2004-12-22 |
2006-07-06 |
Schering Ag |
Tricylische Aminoalkohole, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
|
|
CA2592514A1
(en)
|
2004-12-27 |
2006-07-06 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
EP1841780B1
(en)
|
2005-01-10 |
2011-07-27 |
Glaxo Group Limited |
Androstane 17-alpha-carbonate derivatives for use in the treatment of allergic and inflammatory conditions
|
|
US7402596B2
(en)
|
2005-03-24 |
2008-07-22 |
Renovis, Inc. |
Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
|
|
PE20061193A1
(es)
|
2005-03-25 |
2006-12-02 |
Glaxo Group Ltd |
DERIVADOS DE 3,4-DIHIDROPIRIMIDO[4,5-d]PIRIMIDIN-2-[1H]-0NA COMO INHIBIDORES DE QUINASA p38
|
|
MY145343A
(en)
|
2005-03-25 |
2012-01-31 |
Glaxo Group Ltd |
Novel compounds
|
|
DE102005017301A1
(de)
*
|
2005-04-14 |
2006-10-19 |
Schering Ag |
Substituierte Chromanderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
|
|
DE102005018025A1
(de)
*
|
2005-04-14 |
2006-11-02 |
Schering Ag |
Mehrfach substituierte bizyklische Systeme, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
|
|
DE102005018026B4
(de)
*
|
2005-04-14 |
2006-12-21 |
Schering Ag |
Substituierte Styrole, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
|
|
GB0514809D0
(en)
|
2005-07-19 |
2005-08-24 |
Glaxo Group Ltd |
Compounds
|
|
PE20071068A1
(es)
|
2005-12-20 |
2007-12-13 |
Glaxo Group Ltd |
Acido 3-(4-{[4-(4-{[3-(3,3-dimetil-1-piperidinil)propil]oxi}fenil)-1-piperidinil]carbonil}-1-naftalenil)propanoico o propenoico, sales de los mismos, como antagonistas de los receptores h1 y h3
|
|
EP1834948A1
(de)
|
2006-03-15 |
2007-09-19 |
Bayer Schering Pharma Aktiengesellschaft |
Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
|
|
TWI464148B
(zh)
|
2006-03-16 |
2014-12-11 |
Evotec Us Inc |
作為p2x7調節劑之雙環雜芳基化合物與其用途
|
|
MX2008013411A
(es)
|
2006-04-20 |
2008-11-04 |
Glaxo Group Ltd |
Nuevos compuestos.
|
|
GB0611587D0
(en)
|
2006-06-12 |
2006-07-19 |
Glaxo Group Ltd |
Novel compounds
|
|
KR20090077946A
(ko)
*
|
2006-11-09 |
2009-07-16 |
보오슈 앤드 롬 인코포레이팃드 |
특정 치환된 알코올의 선택된 입체이성질체의 합성
|
|
AU2007329548A1
(en)
|
2006-12-06 |
2008-06-12 |
Boehringer Ingelheim International Gmbh |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
US20080171873A1
(en)
*
|
2007-01-12 |
2008-07-17 |
Harms Arthur E |
Synthesis of selected stereoisomers of certain substituted alcohols
|
|
JP2010520875A
(ja)
|
2007-03-09 |
2010-06-17 |
レノビス, インコーポレイテッド |
P2x7調節因子としてのビシクロヘテロアリール化合物およびその使用
|
|
PE20081889A1
(es)
|
2007-03-23 |
2009-03-05 |
Smithkline Beecham Corp |
Indol carboxamidas como inhibidores de ikk2
|
|
EP2016935A1
(en)
*
|
2007-07-09 |
2009-01-21 |
Intendis GmbH |
Pharmaceutical composition for topical application of poorly soluble compounds
|
|
MX2010012814A
(es)
|
2008-05-23 |
2010-12-20 |
Amira Pharmaceuticals Inc |
Inhibidor de proteina activadora de 5-lipoxigenasa.
|
|
US8163743B2
(en)
|
2008-06-05 |
2012-04-24 |
GlaxoGroupLimited |
4-carboxamide indazole derivatives useful as inhibitors of PI3-kinases
|
|
ES2383246T3
(es)
|
2008-06-05 |
2012-06-19 |
Glaxo Group Limited |
4-amino-indazoles
|
|
EP2300472B1
(en)
|
2008-06-06 |
2012-01-18 |
Boehringer Ingelheim International GmbH |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
WO2010094643A1
(en)
|
2009-02-17 |
2010-08-26 |
Glaxo Group Limited |
Quinoline derivatives and their uses for rhinitis and urticaria
|
|
JP5656880B2
(ja)
|
2009-03-09 |
2015-01-21 |
グラクソ グループ リミテッドGlaxo Group Limited |
Pi3キナーゼの阻害剤としての4−オキサジアゾール−2−イル−インダゾール
|
|
WO2010102968A1
(en)
|
2009-03-10 |
2010-09-16 |
Glaxo Group Limited |
Indole derivatives as ikk2 inhibitors
|
|
EP2408769A1
(en)
|
2009-03-17 |
2012-01-25 |
Glaxo Group Limited |
Pyrimidine derivatives used as itk inhibitors
|
|
JP2012520684A
(ja)
|
2009-03-19 |
2012-09-10 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いたBTBandCNCHomology1(塩基性ロイシンジッパー転写因子1)(Bach1)遺伝子発現のRNA干渉媒介性阻害
|
|
EP2408458A1
(en)
|
2009-03-19 |
2012-01-25 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6 (STAT6) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
US20120029054A1
(en)
|
2009-03-19 |
2012-02-02 |
Merck Sharp & Dohme Corp. |
RNA Interference Mediated Inhibition of GATA Binding Protein 3 (GATA3) Gene Expression Using Short Intefering Nucleic Acid (siNA)
|
|
EP2408916A2
(en)
|
2009-03-19 |
2012-01-25 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
JP2012521760A
(ja)
|
2009-03-27 |
2012-09-20 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いたアポトーシスシグナル調節キナーゼ1(ASK1)遺伝子発現のRNA干渉媒介性阻害
|
|
WO2010111497A2
(en)
|
2009-03-27 |
2010-09-30 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF THE INTERCELLULAR ADHESION MOLECULE 1 (ICAM-1)GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
EP2411018A2
(en)
|
2009-03-27 |
2012-02-01 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF THE NERVE GROWTH FACTOR BETA CHAIN (NGFß) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)
|
|
WO2010111471A2
(en)
|
2009-03-27 |
2010-09-30 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1 (STAT1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
EP2411520A2
(en)
|
2009-03-27 |
2012-02-01 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF THE THYMIC STROMAL LYMPHOPOIETIN (TSLP) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
EP2421834A1
(en)
|
2009-04-24 |
2012-02-29 |
Glaxo Group Limited |
Pyrazole and triazole carboxamides as crac channel inhibitors
|
|
AR076373A1
(es)
|
2009-04-24 |
2011-06-08 |
Glaxo Group Ltd |
N-pirazolil carboxamidas como inhibidores de canales de calcio
|
|
LT2899191T
(lt)
|
2009-04-30 |
2017-10-25 |
Glaxo Group Limited |
Oksazolo pakeistieji indazolai kaip pi3-kinazės inhibitoriai
|
|
US20120220590A1
(en)
|
2009-07-31 |
2012-08-30 |
Thombare Pravin S |
Novel compounds as modulators of glucocorticoid receptors
|
|
WO2011067364A1
(en)
|
2009-12-03 |
2011-06-09 |
Glaxo Group Limited |
Novel compounds
|
|
WO2011067365A1
(en)
|
2009-12-03 |
2011-06-09 |
Glaxo Group Limited |
Benzpyrazole derivatives as inhibitors of p13 kinases
|
|
JP2013512880A
(ja)
|
2009-12-03 |
2013-04-18 |
グラクソ グループ リミテッド |
Pi3−キナーゼ阻害剤としてのインダゾール誘導体
|
|
EP3020393B1
(en)
|
2009-12-16 |
2020-10-07 |
3M Innovative Properties Company |
Formulations and methods for controlling mdi particle size delivery
|
|
WO2011110575A1
(en)
|
2010-03-11 |
2011-09-15 |
Glaxo Group Limited |
Derivatives of 2-[2-(benzo- or pyrido-) thiazolylamino]-6-aminopyridine, useful in the treatment of respiratoric, allergic or inflammatory diseases
|
|
GB201007203D0
(en)
|
2010-04-29 |
2010-06-16 |
Glaxo Group Ltd |
Novel compounds
|
|
RS54286B1
(sr)
|
2010-09-08 |
2016-02-29 |
Glaxosmithkline Intellectual Property Development Limited |
Polimorfi i soli n-[5-[4-(5-{[(2r,6s)-2,6-dimetil-4-morfolinil]metil}-1,3-oksazol-2-il)-1h-indazol-6-il]-2(metiloksi)-3-piridinil]-metansulfonamida
|
|
US9326987B2
(en)
|
2010-09-08 |
2016-05-03 |
Glaxo Group Limited |
Indazole derivatives for use in the treatment of influenza virus infection
|
|
WO2012035055A1
(en)
|
2010-09-17 |
2012-03-22 |
Glaxo Group Limited |
Novel compounds
|
|
EP2630127A1
(en)
|
2010-10-21 |
2013-08-28 |
Glaxo Group Limited |
Pyrazole compounds acting against allergic, inflammatory and immune disorders
|
|
US9156791B2
(en)
|
2010-10-21 |
2015-10-13 |
Glaxo Group Limited |
Pyrazole compounds acting against allergic, immune and inflammatory conditions
|
|
GB201018124D0
(en)
|
2010-10-27 |
2010-12-08 |
Glaxo Group Ltd |
Polymorphs and salts
|
|
EP2683716A1
(en)
|
2011-03-11 |
2014-01-15 |
Glaxo Group Limited |
Pyrido[3,4-b]pyrazine derivatives as syk inhibitors
|
|
GB201104153D0
(en)
|
2011-03-11 |
2011-04-27 |
Glaxo Group Ltd |
Novel compounds
|
|
KR20160060100A
(ko)
|
2013-09-22 |
2016-05-27 |
칼리토르 사이언시즈, 엘엘씨 |
치환된 아미노피리미딘 화합물 및 이용 방법
|
|
RU2016112268A
(ru)
|
2013-10-17 |
2017-11-22 |
Глаксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед |
Ингибитор PI3K для лечения респираторного заболевания
|
|
WO2015055691A1
(en)
|
2013-10-17 |
2015-04-23 |
Glaxosmithkline Intellectual Property Development Limited |
Pi3k inhibitor for treatment of respiratory disease
|
|
WO2015148867A1
(en)
|
2014-03-28 |
2015-10-01 |
Calitor Sciences, Llc |
Substituted heteroaryl compounds and methods of use
|
|
US20170100385A1
(en)
|
2014-05-12 |
2017-04-13 |
Glaxosmithkline Intellectual Property (No. 2) Limited |
Pharmaceutical compositions comprising danirixin for treating infectious diseases
|
|
JP2018527362A
(ja)
|
2015-09-11 |
2018-09-20 |
サンシャイン・レイク・ファーマ・カンパニー・リミテッドSunshine Lake Pharma Co.,Ltd. |
置換されたヘテロアリール化合物および使用方法
|
|
GB201602527D0
(en)
|
2016-02-12 |
2016-03-30 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
|
US20190161480A1
(en)
|
2016-08-08 |
2019-05-30 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical Compounds
|
|
GB201706102D0
(en)
|
2017-04-18 |
2017-05-31 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
|
GB201712081D0
(en)
|
2017-07-27 |
2017-09-13 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
|
WO2019099311A1
(en)
|
2017-11-19 |
2019-05-23 |
Sunshine Lake Pharma Co., Ltd. |
Substituted heteroaryl compounds and methods of use
|
|
KR102737185B1
(ko)
|
2018-01-20 |
2024-12-05 |
선샤인 레이크 파르마 컴퍼니 리미티드 |
치환된 아미노피리미딘 화합물 및 이의 사용 방법
|
|
WO2021191875A1
(en)
|
2020-03-26 |
2021-09-30 |
Glaxosmithkline Intellectual Property Development Limited |
Cathepsin inhibitors for preventing or treating viral infections
|
|
CN113480512B
(zh)
*
|
2021-07-23 |
2022-07-29 |
阜阳欣奕华制药科技有限公司 |
一种1-(7-溴苯并并[d][1,3]二氧杂环戊烯-4-基)乙-1-酮的制备方法
|