JP2005513106A - ヘパリンを保有する眼薬剤 - Google Patents

ヘパリンを保有する眼薬剤 Download PDF

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Publication number
JP2005513106A
JP2005513106A JP2003554209A JP2003554209A JP2005513106A JP 2005513106 A JP2005513106 A JP 2005513106A JP 2003554209 A JP2003554209 A JP 2003554209A JP 2003554209 A JP2003554209 A JP 2003554209A JP 2005513106 A JP2005513106 A JP 2005513106A
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JP
Japan
Prior art keywords
heparin
hyaluronic acid
eye
pharmaceutical composition
use according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003554209A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005513106A5 (enExample
Inventor
グロース ドロテーア
ヘルツァー フランク
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ursapharm Arzneimittel GmbH
Original Assignee
Ursapharm Arzneimittel GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ursapharm Arzneimittel GmbH filed Critical Ursapharm Arzneimittel GmbH
Publication of JP2005513106A publication Critical patent/JP2005513106A/ja
Publication of JP2005513106A5 publication Critical patent/JP2005513106A5/ja
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/717Celluloses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • A61K31/78Polymers containing oxygen of acrylic acid or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • A61K31/787Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79Polymers of vinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
JP2003554209A 2001-12-12 2002-12-11 ヘパリンを保有する眼薬剤 Pending JP2005513106A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10161149A DE10161149B4 (de) 2001-12-12 2001-12-12 Verwendung von Heparin-haltigem Ophthalmikum
PCT/DE2002/004526 WO2003053452A1 (de) 2001-12-12 2002-12-11 Heparin-haltiges ophthalmikum

Publications (2)

Publication Number Publication Date
JP2005513106A true JP2005513106A (ja) 2005-05-12
JP2005513106A5 JP2005513106A5 (enExample) 2006-02-09

Family

ID=7709005

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003554209A Pending JP2005513106A (ja) 2001-12-12 2002-12-11 ヘパリンを保有する眼薬剤

Country Status (11)

Country Link
US (1) US20050043271A1 (enExample)
EP (1) EP1453523B1 (enExample)
JP (1) JP2005513106A (enExample)
CN (1) CN1604784A (enExample)
AT (1) ATE318607T1 (enExample)
AU (1) AU2002357972A1 (enExample)
CA (1) CA2468775A1 (enExample)
DE (2) DE10161149B4 (enExample)
ES (1) ES2259727T3 (enExample)
MX (1) MXPA04005390A (enExample)
WO (1) WO2003053452A1 (enExample)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010534225A (ja) * 2007-07-23 2010-11-04 アグロ インダストリ ルシュルシェ エ デベロップメンツ エー.アール.ディー. 皮膚、眼および粘膜の保護機能改善用組成物を製造するためのヒアルロン酸の使用
JP2014159488A (ja) * 2008-11-20 2014-09-04 Lab Derivati Organici Spa ヘパラン硫酸の精製方法並びに美容用及び皮膚用調製物中におけるその使用
JP2019511494A (ja) * 2016-03-07 2019-04-25 ウルサファルム アルツナイミッテル ゲゼルシャフト ミット ベシュレンクテル ハフツング 眼科用組成物
JP2019532105A (ja) * 2016-10-14 2019-11-07 アイ.コム メディカル ゲーエムベーハー 角結膜のホメオスタシスを確立、回復及び維持するための方法
JP2020525416A (ja) * 2017-06-29 2020-08-27 アドヴァイテ エルエルシー. 眼表面障害の治療及び診断
JP2021511317A (ja) * 2018-01-18 2021-05-06 ファエス・ファルマ・ソシエダッド・アノニマFaes Farma, S.A. ビラスチン、β−シクロデキストリンおよび少なくとも1種のゲル化剤を含有する眼科用組成物
JP2023060015A (ja) * 2014-06-10 2023-04-27 ロート製薬株式会社 眼科用組成物
WO2024024920A1 (ja) * 2022-07-29 2024-02-01 マルホ株式会社 眼科用組成物
US12268706B2 (en) 2019-01-31 2025-04-08 i.com medical GmbH Hyaluronic acid for relief of idiopathic ocular pain
US12303527B2 (en) 2018-04-18 2025-05-20 i.com medical GmbH High molecular weight hyaluronic acid for treatment and prevention of severe ocular surface disease

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001244713A1 (en) * 2000-04-03 2001-10-15 Santen Pharmaceutical Co. Ltd. Transporters and drug delivery system by using the same
WO2004093878A1 (en) * 2003-04-16 2004-11-04 Alcon, Inc. Use of fused pyridazine derivatives for treating dry eye disorders
DE10360425A1 (de) * 2003-12-19 2005-07-28 Ursapharm Arzneimittel Gmbh & Co. Kg Verwendung von Hyaluronsäure, Hyaluronat und/oder deren Derivate zur Herstellung einer pharmazeutischen Zusammensetzung
JP2005187407A (ja) * 2003-12-25 2005-07-14 Lion Corp アレルギー眼疾患用眼科組成物
DE102004002001A1 (de) 2004-01-14 2005-08-11 Reinmüller, Johannes, Dr.med. Mittel zur Behandlung von entzündlichen Erkrankungen
DE102005035986B4 (de) * 2005-07-28 2009-10-15 Bausch & Lomb Incorporated Steriles tropfbares mehrphasiges emulgatorfreies ophthalmisches Präparat
DE102005055275A1 (de) * 2005-11-17 2007-05-24 Ursapharm Arzneimittel Gmbh & Co. Kg Phosphatfreie pharmazeutische Zusammensetzung sowie deren Verwendung
DE102006049091A1 (de) * 2006-10-18 2008-04-24 Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh Emulgatorfreies ophthalmisches Präparat enthaltend Pflanzenöl
US20110065643A1 (en) 2009-06-12 2011-03-17 University Of Southern California Clusterin Pharmaceuticals and Treatment Methods Using the Same
FR2962044B1 (fr) * 2010-04-21 2013-02-22 Horus Pharma Emulsion lacrymimetique
JP7333919B2 (ja) * 2017-09-05 2023-08-28 エクセル メッド、エルエルシー 虚血を治療するためのヘパリン組成物
CN116139067B (zh) * 2021-11-22 2024-03-22 华熙生物科技股份有限公司 透明质酸锌形成凝胶的方法及含有透明质酸锌的滴眼凝胶及其制备

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3232833A (en) * 1962-01-17 1966-02-01 Riviere Charles Heparin containing compositions
DE3440352A1 (de) * 1984-11-05 1986-05-07 Dr. Thilo & Co GmbH, 8029 Sauerlach Dry-eye-packung
JPS635745A (ja) * 1986-04-04 1988-01-11 アラ−ガン・インコ−ポレイテツド 角膜創傷治癒用組成物
JPH02167233A (ja) * 1988-11-10 1990-06-27 Kiyoshi Kita 眼内手術補助剤
JPH06192130A (ja) * 1992-09-30 1994-07-12 Union Carbide Chem & Plast Technol Corp ムコ接着性ポリマー
JPH08169835A (ja) * 1994-07-25 1996-07-02 Lab Medidom Sa 人工涙として使用するための眼用製剤
DE19547972A1 (de) * 1995-12-21 1997-07-10 Weropharm Gmbh Heparin zur Prophylaxe und akuten Therapie der allergischen Konjunktivitis
WO2001074330A2 (en) * 2000-04-04 2001-10-11 Bausch & Lomb Incorporated Method for treating dry eye

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6479103A (en) * 1987-06-09 1989-03-24 Lion Corp External preparation
DK505488D0 (da) * 1987-12-21 1988-09-09 Bar Shalom Daniel Middel og anvendelse af samme
US5141741A (en) * 1988-12-09 1992-08-25 Lion Corporation Anti-sunburn skin-care preparation
DE19520575A1 (de) * 1995-06-06 1996-12-12 Permselect Ges Fuer Zellstrukt Hautwirksame Kombination von Mucopolysacchariden
US6372755B2 (en) * 1997-07-11 2002-04-16 Toray Industries, Inc. Stable medicinal compositions containing 4,5-epoxymorphinan derivatives

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3232833A (en) * 1962-01-17 1966-02-01 Riviere Charles Heparin containing compositions
DE3440352A1 (de) * 1984-11-05 1986-05-07 Dr. Thilo & Co GmbH, 8029 Sauerlach Dry-eye-packung
JPS635745A (ja) * 1986-04-04 1988-01-11 アラ−ガン・インコ−ポレイテツド 角膜創傷治癒用組成物
JPH02167233A (ja) * 1988-11-10 1990-06-27 Kiyoshi Kita 眼内手術補助剤
JPH06192130A (ja) * 1992-09-30 1994-07-12 Union Carbide Chem & Plast Technol Corp ムコ接着性ポリマー
JPH08169835A (ja) * 1994-07-25 1996-07-02 Lab Medidom Sa 人工涙として使用するための眼用製剤
DE19547972A1 (de) * 1995-12-21 1997-07-10 Weropharm Gmbh Heparin zur Prophylaxe und akuten Therapie der allergischen Konjunktivitis
WO2001074330A2 (en) * 2000-04-04 2001-10-11 Bausch & Lomb Incorporated Method for treating dry eye

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010534225A (ja) * 2007-07-23 2010-11-04 アグロ インダストリ ルシュルシェ エ デベロップメンツ エー.アール.ディー. 皮膚、眼および粘膜の保護機能改善用組成物を製造するためのヒアルロン酸の使用
JP2014159488A (ja) * 2008-11-20 2014-09-04 Lab Derivati Organici Spa ヘパラン硫酸の精製方法並びに美容用及び皮膚用調製物中におけるその使用
JP2023060015A (ja) * 2014-06-10 2023-04-27 ロート製薬株式会社 眼科用組成物
JP2019511494A (ja) * 2016-03-07 2019-04-25 ウルサファルム アルツナイミッテル ゲゼルシャフト ミット ベシュレンクテル ハフツング 眼科用組成物
JP2019532105A (ja) * 2016-10-14 2019-11-07 アイ.コム メディカル ゲーエムベーハー 角結膜のホメオスタシスを確立、回復及び維持するための方法
JP2022153583A (ja) * 2016-10-14 2022-10-12 アイ.コム メディカル ゲーエムベーハー 角結膜のホメオスタシスを確立、回復及び維持するための方法
JP2020525416A (ja) * 2017-06-29 2020-08-27 アドヴァイテ エルエルシー. 眼表面障害の治療及び診断
JP2021511317A (ja) * 2018-01-18 2021-05-06 ファエス・ファルマ・ソシエダッド・アノニマFaes Farma, S.A. ビラスチン、β−シクロデキストリンおよび少なくとも1種のゲル化剤を含有する眼科用組成物
JP7309729B2 (ja) 2018-01-18 2023-07-18 ファエス・ファルマ・ソシエダッド・アノニマ ビラスチン、β-シクロデキストリンおよび少なくとも1種のゲル化剤を含有する眼科用組成物
US12303527B2 (en) 2018-04-18 2025-05-20 i.com medical GmbH High molecular weight hyaluronic acid for treatment and prevention of severe ocular surface disease
US12268706B2 (en) 2019-01-31 2025-04-08 i.com medical GmbH Hyaluronic acid for relief of idiopathic ocular pain
WO2024024920A1 (ja) * 2022-07-29 2024-02-01 マルホ株式会社 眼科用組成物

Also Published As

Publication number Publication date
EP1453523B1 (de) 2006-03-01
CA2468775A1 (en) 2003-07-03
DE10161149B4 (de) 2007-03-08
WO2003053452A1 (de) 2003-07-03
DE50205968D1 (de) 2006-04-27
DE10161149A1 (de) 2003-06-26
US20050043271A1 (en) 2005-02-24
CN1604784A (zh) 2005-04-06
MXPA04005390A (es) 2005-10-18
ATE318607T1 (de) 2006-03-15
AU2002357972A1 (en) 2003-07-09
ES2259727T3 (es) 2006-10-16
EP1453523A1 (de) 2004-09-08

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