JP2005508599A5 - - Google Patents
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- Publication number
- JP2005508599A5 JP2005508599A5 JP2002546688A JP2002546688A JP2005508599A5 JP 2005508599 A5 JP2005508599 A5 JP 2005508599A5 JP 2002546688 A JP2002546688 A JP 2002546688A JP 2002546688 A JP2002546688 A JP 2002546688A JP 2005508599 A5 JP2005508599 A5 JP 2005508599A5
- Authority
- JP
- Japan
- Prior art keywords
- probe
- dna
- primer
- complementary
- dna polymerase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 39
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 claims 26
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 claims 26
- 239000000523 sample Substances 0.000 claims 26
- 108020004414 DNA Proteins 0.000 claims 25
- 230000000295 complement effect Effects 0.000 claims 23
- 102000039446 nucleic acids Human genes 0.000 claims 18
- 108020004707 nucleic acids Proteins 0.000 claims 18
- 150000007523 nucleic acids Chemical class 0.000 claims 18
- 108020004999 messenger RNA Proteins 0.000 claims 13
- 102000053602 DNA Human genes 0.000 claims 12
- 239000003446 ligand Substances 0.000 claims 9
- 108010061982 DNA Ligases Proteins 0.000 claims 8
- 102000004190 Enzymes Human genes 0.000 claims 8
- 108090000790 Enzymes Proteins 0.000 claims 8
- 108020004682 Single-Stranded DNA Proteins 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 8
- 239000002299 complementary DNA Substances 0.000 claims 7
- 102000012410 DNA Ligases Human genes 0.000 claims 6
- 239000011230 binding agent Substances 0.000 claims 6
- 238000006073 displacement reaction Methods 0.000 claims 6
- 230000000694 effects Effects 0.000 claims 6
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 4
- 102100034343 Integrase Human genes 0.000 claims 4
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- 238000001514 detection method Methods 0.000 claims 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 2
- 101710203526 Integrase Proteins 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 108091034117 Oligonucleotide Proteins 0.000 claims 2
- 101710086015 RNA ligase Proteins 0.000 claims 2
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 claims 2
- 238000012197 amplification kit Methods 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 150000001718 carbodiimides Chemical class 0.000 claims 2
- ATDGTVJJHBUTRL-UHFFFAOYSA-N cyanogen bromide Chemical group BrC#N ATDGTVJJHBUTRL-UHFFFAOYSA-N 0.000 claims 2
- 230000029087 digestion Effects 0.000 claims 2
- 238000007899 nucleic acid hybridization Methods 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 229920000936 Agarose Polymers 0.000 claims 1
- 108090001008 Avidin Proteins 0.000 claims 1
- 108010090804 Streptavidin Proteins 0.000 claims 1
- 230000003321 amplification Effects 0.000 claims 1
- -1 antibody Proteins 0.000 claims 1
- 238000001574 biopsy Methods 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 229960002685 biotin Drugs 0.000 claims 1
- 235000020958 biotin Nutrition 0.000 claims 1
- 239000011616 biotin Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 229910001385 heavy metal Inorganic materials 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 210000000265 leukocyte Anatomy 0.000 claims 1
- 238000003199 nucleic acid amplification method Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 229920002401 polyacrylamide Polymers 0.000 claims 1
- 108091008146 restriction endonucleases Proteins 0.000 claims 1
- 238000010839 reverse transcription Methods 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 238000012360 testing method Methods 0.000 claims 1
- 125000004149 thio group Chemical group *S* 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/728,265 US6593086B2 (en) | 1996-05-20 | 2000-12-01 | Nucleic acid amplification methods |
| PCT/US2001/045822 WO2002044339A2 (en) | 2000-12-01 | 2001-12-03 | Nucleic acid amplification methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005508599A JP2005508599A (ja) | 2005-04-07 |
| JP2005508599A5 true JP2005508599A5 (https=) | 2005-06-23 |
Family
ID=24926117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002546688A Pending JP2005508599A (ja) | 2000-12-01 | 2001-12-03 | 核酸の増幅方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6593086B2 (https=) |
| EP (1) | EP1343916A4 (https=) |
| JP (1) | JP2005508599A (https=) |
| AU (2) | AU2013202A (https=) |
| CA (1) | CA2430373A1 (https=) |
| WO (1) | WO2002044339A2 (https=) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040018491A1 (en) * | 2000-10-26 | 2004-01-29 | Kevin Gunderson | Detection of nucleic acid reactions on bead arrays |
| US20030175828A1 (en) * | 2002-03-15 | 2003-09-18 | Lazar James G. | Signal amplification by Hybrid Capture |
| US20030236205A1 (en) * | 2002-06-21 | 2003-12-25 | Zhang David Y. | Hybridization signal amplification method (HSAM) nanostructures for diagnostic and therapeutic uses |
| US20050118616A1 (en) * | 2002-08-16 | 2005-06-02 | Kawashima Tadashi R. | Amplification of target nucleotide sequence without polymerase chain reaction |
| GB0230238D0 (en) * | 2002-12-28 | 2003-02-05 | Fu Guoliang | Combined exponential and linear amplification |
| AU2003301219A1 (en) * | 2002-12-23 | 2004-07-22 | Dahl, Gary, A. | Target-dependent transcription |
| DE602004005711T2 (de) * | 2003-06-02 | 2007-12-27 | Check-Points Holding B.V. | Schnell-verfahren zur detektion von mikroorganismen in lebensmittelproben |
| WO2005054466A2 (en) † | 2003-07-25 | 2005-06-16 | Ambion, Inc. | Methods and compositions for preparing rna from a fixed sample |
| US20050112591A1 (en) * | 2003-11-25 | 2005-05-26 | Applera Corporation | Novel method for isolating single stranded product |
| US7566532B1 (en) | 2004-07-02 | 2009-07-28 | Quest Diagnostics Investments Incorporated | Methods for detecting retroviruses |
| US7309589B2 (en) | 2004-08-20 | 2007-12-18 | Vironix Llc | Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16S ribosomal RNA gene and identification of bacterial species by amplicon sequencing |
| DE502006008765D1 (de) * | 2005-06-23 | 2011-03-03 | Siemens Healthcare Diagnostics | Magnetpartikel mit einer geschlossenen, ultradünnen silikaschicht, verfahren zu deren herstellung und verwendung |
| US20090137415A1 (en) * | 2005-08-05 | 2009-05-28 | Euclid Diagnostics Llc | SUBTRACTIVE SEPARATION AND AMPLIFICATION OF NON-RIBOSOMAL TRANSCRIBED RNA (nrRNA) |
| WO2007092538A2 (en) * | 2006-02-07 | 2007-08-16 | President And Fellows Of Harvard College | Methods for making nucleotide probes for sequencing and synthesis |
| EP2027293B1 (en) * | 2006-05-24 | 2014-11-19 | Gen-Probe Incorporated | Method of lysing mycobacterium and amplifying its nucleic acid |
| WO2008027977A2 (en) | 2006-08-30 | 2008-03-06 | The Arizona Board Of Regents, A Body Coporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University | High speed, high fidelity, high sensitivity nucleic acid detection |
| EP2058396A4 (en) | 2006-08-31 | 2010-06-30 | Toyo Seikan Kaisha Ltd | nucleic acid amplification |
| US20080090238A1 (en) * | 2006-10-12 | 2008-04-17 | Dan-Hui Dorothy Yang | Increased sensitivity of proximity ligation assays |
| US20100047792A1 (en) * | 2007-04-10 | 2010-02-25 | Szendroe Istvan | Label-free optical detection method |
| US20090181389A1 (en) * | 2008-01-11 | 2009-07-16 | Signosis, Inc., A California Corporation | Quantitative measurement of nucleic acid via ligation-based linear amplification |
| WO2010068702A2 (en) * | 2008-12-10 | 2010-06-17 | Illumina, Inc. | Methods and compositions for hybridizing nucleic acids |
| WO2013010074A1 (en) | 2011-07-13 | 2013-01-17 | Primeradx, Inc. | Multimodal methods for simultaneous detection and quantification of multiple nucleic acids in a sample |
| CN104093854A (zh) * | 2011-12-02 | 2014-10-08 | 凯杰有限公司 | 表征组合物中的rna的方法和试剂盒 |
| US9193994B2 (en) * | 2012-04-20 | 2015-11-24 | Samsung Electronics Co., Ltd. | Polynucleotide and use thereof |
| WO2014071070A1 (en) * | 2012-11-01 | 2014-05-08 | Pacific Biosciences Of California, Inc. | Compositions and methods for selection of nucleic acids |
| KR20150029432A (ko) * | 2013-09-10 | 2015-03-18 | 삼성전자주식회사 | 핵산 검출 방법 |
| US11286519B2 (en) | 2013-12-11 | 2022-03-29 | Accuragen Holdings Limited | Methods and compositions for enrichment of amplification products |
| WO2017062863A1 (en) | 2015-10-09 | 2017-04-13 | Accuragen Holdings Limited | Methods and compositions for enrichment of amplification products |
| US11859246B2 (en) | 2013-12-11 | 2024-01-02 | Accuragen Holdings Limited | Methods and compositions for enrichment of amplification products |
| US10767222B2 (en) | 2013-12-11 | 2020-09-08 | Accuragen Holdings Limited | Compositions and methods for detecting rare sequence variants |
| US11987836B2 (en) | 2014-09-30 | 2024-05-21 | Global Life Sciences Solutions Usa Llc | Method for nucleic acid analysis directly from an unpurified biological sample |
| CN107208137A (zh) * | 2014-10-20 | 2017-09-26 | 龙公司 | 检测rna病毒的组合物和方法 |
| MA40473A (fr) * | 2014-10-22 | 2016-04-28 | Int Partnership For Microbicides Inc | Dispositifs d'administration de médicaments à base d'une silicone catalysée par du platine, et leurs procédés d'utilisation |
| CN105803055A (zh) * | 2014-12-31 | 2016-07-27 | 天昊生物医药科技（苏州）有限公司 | 一种基于多重循环延伸连接的靶基因区域富集新方法 |
| WO2017096322A1 (en) | 2015-12-03 | 2017-06-08 | Accuragen Holdings Limited | Methods and compositions for forming ligation products |
| CN109511265B (zh) | 2016-05-16 | 2023-07-14 | 安可济控股有限公司 | 通过链鉴定改进测序的方法 |
| CN109844133A (zh) | 2016-08-15 | 2019-06-04 | 安可济控股有限公司 | 检测罕见序列变体的组合物和方法 |
| US10626473B2 (en) * | 2016-10-03 | 2020-04-21 | Genetics & IVG Institute, Inc. | Methods and compositions for detecting Zika virus |
| KR102371222B1 (ko) * | 2017-11-29 | 2022-03-07 | 주식회사 파나진 | 표적핵산 증폭방법 및 표적핵산 증폭용 조성물 |
| US10859997B1 (en) | 2017-12-04 | 2020-12-08 | Omax Corporation | Numerically controlled machining |
| WO2019241290A1 (en) | 2018-06-12 | 2019-12-19 | Accuragen Holdings Limited | Methods and compositions for forming ligation products |
| GB201812192D0 (en) | 2018-07-26 | 2018-09-12 | Ttp Plc | Variable temperature reactor, heater and control circuit for the same |
| CN112770776B (zh) | 2018-07-30 | 2025-08-19 | 瑞德库尔有限责任公司 | 用于样品处理或分析的方法和系统 |
| WO2020033394A1 (en) * | 2018-08-06 | 2020-02-13 | Northwestern University | Enhanced capture of target nucleic acids |
| KR20210043605A (ko) * | 2018-08-14 | 2021-04-21 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵산의 체외 검출 |
| CN110066890A (zh) * | 2019-06-03 | 2019-07-30 | 广西大学 | 一种快速检测ibv二温式纳米pcr试剂盒及应用 |
| WO2021119202A1 (en) * | 2019-12-10 | 2021-06-17 | Enumerix, Inc. | Compositions and methods of nucleic acid amplification |
| EP4097251A1 (en) | 2020-01-29 | 2022-12-07 | 10X Genomics, Inc. | Compositions and methods for analyte detection |
| CN113528513B (zh) * | 2021-08-12 | 2022-11-22 | 基因科技（上海）股份有限公司 | 原位杂交探针复合体、其制备方法及应用 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4786600A (en) | 1984-05-25 | 1988-11-22 | The Trustees Of Columbia University In The City Of New York | Autocatalytic replication of recombinant RNA |
| US4957858A (en) | 1986-04-16 | 1990-09-18 | The Salk Instute For Biological Studies | Replicative RNA reporter systems |
| US5118605A (en) | 1984-10-16 | 1992-06-02 | Chiron Corporation | Polynucleotide determination with selectable cleavage sites |
| US4883750A (en) | 1984-12-13 | 1989-11-28 | Applied Biosystems, Inc. | Detection of specific sequences in nucleic acids |
| US4925785A (en) | 1986-03-07 | 1990-05-15 | Biotechnica Diagnostics, Inc. | Nucleic acid hybridization assays |
| US4980456A (en) * | 1987-04-06 | 1990-12-25 | Scripps Clinic And Research Foundation | Recombinant factor VIIIC derived fragments |
| US5449602A (en) | 1988-01-13 | 1995-09-12 | Amoco Corporation | Template-directed photoligation |
| ATE92538T1 (de) | 1988-01-21 | 1993-08-15 | Genentech Inc | Verstaerkung und nachweis von nukleinsaeuresequenzen. |
| US4988617A (en) | 1988-03-25 | 1991-01-29 | California Institute Of Technology | Method of detecting a nucleotide change in nucleic acids |
| EP0426756A4 (en) | 1988-07-26 | 1991-11-21 | Genelabs Incorporated | Rna and dna amplification techniques |
| US5185243A (en) | 1988-08-25 | 1993-02-09 | Syntex (U.S.A.) Inc. | Method for detection of specific nucleic acid sequences |
| US5118801A (en) | 1988-09-30 | 1992-06-02 | The Public Health Research Institute | Nucleic acid process containing improved molecular switch |
| US5112734A (en) | 1989-05-26 | 1992-05-12 | Gene-Trak Systems | Target-dependent synthesis of an artificial gene for the synthesis of a replicatable rna |
| US5200314A (en) | 1990-03-23 | 1993-04-06 | Chiron Corporation | Polynucleotide capture assay employing in vitro amplification |
| CA2046713A1 (en) | 1990-10-16 | 1992-04-17 | Richard M. Martinelli | Amplification of midivariant dna templates |
| ATE159763T1 (de) | 1990-12-31 | 1997-11-15 | Promega Corp | Nuklein-säure amplifikation mit dns abhängigen rns polymerasen aktivität von rns-replikasen |
| JP3080178B2 (ja) | 1991-02-18 | 2000-08-21 | 東洋紡績株式会社 | 核酸配列の増幅方法およびそのための試薬キット |
| JP3085409B2 (ja) | 1991-03-29 | 2000-09-11 | 東洋紡績株式会社 | 標的核酸配列の検出方法およびそのための試薬キット |
| DE4214112A1 (de) * | 1991-08-02 | 1993-02-04 | Europ Lab Molekularbiolog | Neues verfahren zur sequenzierung von nukleinsaeuren |
| CA2124797C (en) | 1991-12-23 | 2004-03-30 | Bruce D. Irvine | Hiv probes for use in solution phase sandwich hybridization assays |
| US6261808B1 (en) | 1992-08-04 | 2001-07-17 | Replicon, Inc. | Amplification of nucleic acid molecules via circular replicons |
| WO1994003624A1 (en) | 1992-08-04 | 1994-02-17 | Auerbach Jeffrey I | Methods for the isothermal amplification of nucleic acid molecules |
| US5834202A (en) | 1992-08-04 | 1998-11-10 | Replicon, Inc. | Methods for the isothermal amplification of nucleic acid molecules |
| CA2155186A1 (en) * | 1993-02-01 | 1994-08-18 | Kevin M. Ulmer | Methods and apparatus for dna sequencing |
| US5422252A (en) | 1993-06-04 | 1995-06-06 | Becton, Dickinson And Company | Simultaneous amplification of multiple targets |
| US5601978A (en) | 1993-09-03 | 1997-02-11 | Abbott Laboratories | Oligonucleotides and methods for the detection of chlamydia trachomatis |
| NL9301957A (nl) | 1993-11-11 | 1995-06-01 | U Gene Research Bv | Werkwijze voor het identificeren van micro-organismen, en daarvoor bruikbare hulpmiddelen. |
| US5523204A (en) | 1993-12-10 | 1996-06-04 | Becton Dickinson And Company | Detection of nucleic acids in cells by strand displacement amplification |
| SE9400522D0 (sv) | 1994-02-16 | 1994-02-16 | Ulf Landegren | Method and reagent for detecting specific nucleotide sequences |
| US5876924A (en) * | 1994-06-22 | 1999-03-02 | Mount Sinai School Of Medicine | Nucleic acid amplification method hybridization signal amplification method (HSAM) |
| EP0717782A1 (en) | 1994-06-22 | 1996-06-26 | Mount Sinai School Of Medicine Of The City University Of New York | Ligation-dependent amplification for the detection of infectious pathogens and abnormal genes |
| US5942391A (en) * | 1994-06-22 | 1999-08-24 | Mount Sinai School Of Medicine | Nucleic acid amplification method: ramification-extension amplification method (RAM) |
| US5773268A (en) * | 1994-11-09 | 1998-06-30 | Cedars-Sinai Medical Center | Chromosome 21 gene marker, compositions and methods using same |
| US5616465A (en) | 1995-08-09 | 1997-04-01 | The Regents Of The University Of California | Detection and isolation of nucleic acid sequences using competitive hybridization probes |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| DK0862656T3 (da) | 1995-11-21 | 2001-04-09 | Univ Yale | Unimolekylær segmentamplifikation og -detektering |
| US6162965A (en) * | 1997-06-02 | 2000-12-19 | Novartis Ag | Plant transformation methods |
| US6124120A (en) | 1997-10-08 | 2000-09-26 | Yale University | Multiple displacement amplification |
| WO2000004193A1 (en) | 1998-07-20 | 2000-01-27 | Yale University | Method for detecting nucleic acids using target-mediated ligation of bipartite primers |
| JP2002525049A (ja) | 1998-09-15 | 2002-08-13 | イェール ユニバーシティ | ローリングサークル増幅を用いる分子クローニング |
| EP1112385A1 (en) | 1998-09-15 | 2001-07-04 | Yale University | Artificial long terminal repeat vectors |
| JP2002540802A (ja) | 1999-04-06 | 2002-12-03 | イェール ユニバーシティ | 配列標識の固定されたアドレス分析 |
| WO2001012855A2 (en) | 1999-08-13 | 2001-02-22 | Yale University | Binary encoded sequence tags |
-
2000
- 2000-12-01 US US09/728,265 patent/US6593086B2/en not_active Expired - Lifetime
-
2001
- 2001-12-03 WO PCT/US2001/045822 patent/WO2002044339A2/en not_active Ceased
- 2001-12-03 EP EP01998621A patent/EP1343916A4/en not_active Ceased
- 2001-12-03 JP JP2002546688A patent/JP2005508599A/ja active Pending
- 2001-12-03 AU AU2013202A patent/AU2013202A/xx active Pending
- 2001-12-03 AU AU2002220132A patent/AU2002220132B2/en not_active Ceased
- 2001-12-03 CA CA002430373A patent/CA2430373A1/en not_active Abandoned
-
2003
- 2003-06-13 US US10/461,848 patent/US8632999B1/en not_active Expired - Lifetime
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