JP2005503390A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005503390A5 JP2005503390A5 JP2003522508A JP2003522508A JP2005503390A5 JP 2005503390 A5 JP2005503390 A5 JP 2005503390A5 JP 2003522508 A JP2003522508 A JP 2003522508A JP 2003522508 A JP2003522508 A JP 2003522508A JP 2005503390 A5 JP2005503390 A5 JP 2005503390A5
- Authority
- JP
- Japan
- Prior art keywords
- methacrylate
- acrylate
- transdermal therapeutic
- therapeutic system
- content
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000178 monomer Substances 0.000 claims 8
- 230000001225 therapeutic effect Effects 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 7
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical group COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 4
- -1 anesthetic Substances 0.000 claims 4
- 229940088597 hormone Drugs 0.000 claims 4
- 239000005556 hormone Substances 0.000 claims 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 3
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 239000011159 matrix material Substances 0.000 claims 3
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol group Chemical group [C@@H]12CC[C@H](O)[C@@]1(C)CC[C@@H]1C3=C(CC[C@@H]21)C=C(O)C=C3 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 claims 2
- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical compound OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 claims 2
- GNSFRPWPOGYVLO-UHFFFAOYSA-N 3-hydroxypropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCCO GNSFRPWPOGYVLO-UHFFFAOYSA-N 0.000 claims 2
- QZPSOSOOLFHYRR-UHFFFAOYSA-N 3-hydroxypropyl prop-2-enoate Chemical compound OCCCOC(=O)C=C QZPSOSOOLFHYRR-UHFFFAOYSA-N 0.000 claims 2
- SOGAXMICEFXMKE-UHFFFAOYSA-N Butylmethacrylate Chemical compound CCCCOC(=O)C(C)=C SOGAXMICEFXMKE-UHFFFAOYSA-N 0.000 claims 2
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims 2
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 claims 2
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 claims 2
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 claims 2
- 230000000202 analgesic effect Effects 0.000 claims 2
- 239000003963 antioxidant agent Substances 0.000 claims 2
- 229920001400 block copolymer Polymers 0.000 claims 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 239000003431 cross linking reagent Substances 0.000 claims 2
- 125000000524 functional group Chemical group 0.000 claims 2
- 229920001519 homopolymer Polymers 0.000 claims 2
- 230000003533 narcotic effect Effects 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 238000006116 polymerization reaction Methods 0.000 claims 2
- 239000003087 receptor blocking agent Substances 0.000 claims 2
- 125000001424 substituent group Chemical group 0.000 claims 2
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 claims 1
- BFPYWIDHMRZLRN-UHFFFAOYSA-N 17alpha-ethynyl estradiol Natural products OC1=CC=C2C3CCC(C)(C(CC4)(O)C#C)C4C3CCC2=C1 BFPYWIDHMRZLRN-UHFFFAOYSA-N 0.000 claims 1
- STMDPCBYJCIZOD-UHFFFAOYSA-N 2-(2,4-dinitroanilino)-4-methylpentanoic acid Chemical compound CC(C)CC(C(O)=O)NC1=CC=C([N+]([O-])=O)C=C1[N+]([O-])=O STMDPCBYJCIZOD-UHFFFAOYSA-N 0.000 claims 1
- WDQMWEYDKDCEHT-UHFFFAOYSA-N 2-ethylhexyl 2-methylprop-2-enoate Chemical compound CCCCC(CC)COC(=O)C(C)=C WDQMWEYDKDCEHT-UHFFFAOYSA-N 0.000 claims 1
- XOHZOHVCPWPCEJ-UHFFFAOYSA-N 2-ethylhexyl prop-2-enoate;ethyl prop-2-enoate Chemical compound CCOC(=O)C=C.CCCCC(CC)COC(=O)C=C XOHZOHVCPWPCEJ-UHFFFAOYSA-N 0.000 claims 1
- RUMACXVDVNRZJZ-UHFFFAOYSA-N 2-methylpropyl 2-methylprop-2-enoate Chemical compound CC(C)COC(=O)C(C)=C RUMACXVDVNRZJZ-UHFFFAOYSA-N 0.000 claims 1
- XBIUWALDKXACEA-UHFFFAOYSA-N 3-[bis(2,4-dioxopentan-3-yl)alumanyl]pentane-2,4-dione Chemical compound CC(=O)C(C(C)=O)[Al](C(C(C)=O)C(C)=O)C(C(C)=O)C(C)=O XBIUWALDKXACEA-UHFFFAOYSA-N 0.000 claims 1
- 229940127291 Calcium channel antagonist Drugs 0.000 claims 1
- 239000004821 Contact adhesive Substances 0.000 claims 1
- 101000783577 Dendroaspis angusticeps Thrombostatin Proteins 0.000 claims 1
- 101000783578 Dendroaspis jamesoni kaimosae Dendroaspin Proteins 0.000 claims 1
- BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 claims 1
- 206010058359 Hypogonadism Diseases 0.000 claims 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims 1
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims 1
- IMONTRJLAWHYGT-ZCPXKWAGSA-N Norethindrone Acetate Chemical compound C1CC2=CC(=O)CC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CC[C@](C#C)(OC(=O)C)[C@@]1(C)CC2 IMONTRJLAWHYGT-ZCPXKWAGSA-N 0.000 claims 1
- 229930182555 Penicillin Natural products 0.000 claims 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 claims 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 claims 1
- IAXXETNIOYFMLW-COPLHBTASA-N [(1s,3s,4s)-4,7,7-trimethyl-3-bicyclo[2.2.1]heptanyl] 2-methylprop-2-enoate Chemical compound C1C[C@]2(C)[C@@H](OC(=O)C(=C)C)C[C@H]1C2(C)C IAXXETNIOYFMLW-COPLHBTASA-N 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 239000000695 adrenergic alpha-agonist Substances 0.000 claims 1
- 239000000808 adrenergic beta-agonist Substances 0.000 claims 1
- 102000004305 alpha Adrenergic Receptors Human genes 0.000 claims 1
- 108090000861 alpha Adrenergic Receptors Proteins 0.000 claims 1
- 230000003444 anaesthetic effect Effects 0.000 claims 1
- 230000002280 anti-androgenic effect Effects 0.000 claims 1
- 230000003257 anti-anginal effect Effects 0.000 claims 1
- 230000001430 anti-depressive effect Effects 0.000 claims 1
- 230000001387 anti-histamine Effects 0.000 claims 1
- 239000000043 antiallergic agent Substances 0.000 claims 1
- 239000000051 antiandrogen Substances 0.000 claims 1
- 239000003416 antiarrhythmic agent Substances 0.000 claims 1
- 239000000935 antidepressant agent Substances 0.000 claims 1
- 229940005513 antidepressants Drugs 0.000 claims 1
- 229940125708 antidiabetic agent Drugs 0.000 claims 1
- 239000003472 antidiabetic agent Substances 0.000 claims 1
- 239000000739 antihistaminic agent Substances 0.000 claims 1
- 229940125684 antimigraine agent Drugs 0.000 claims 1
- 239000002282 antimigraine agent Substances 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 229940127218 antiplatelet drug Drugs 0.000 claims 1
- 239000003420 antiserotonin agent Substances 0.000 claims 1
- 229920005601 base polymer Polymers 0.000 claims 1
- 102000012740 beta Adrenergic Receptors Human genes 0.000 claims 1
- 108010079452 beta Adrenergic Receptors Proteins 0.000 claims 1
- 229940124630 bronchodilator Drugs 0.000 claims 1
- RNOOHTVUSNIPCJ-UHFFFAOYSA-N butan-2-yl prop-2-enoate Chemical compound CCC(C)OC(=O)C=C RNOOHTVUSNIPCJ-UHFFFAOYSA-N 0.000 claims 1
- CQEYYJKEWSMYFG-UHFFFAOYSA-N butyl acrylate Chemical class CCCCOC(=O)C=C CQEYYJKEWSMYFG-UHFFFAOYSA-N 0.000 claims 1
- 239000000480 calcium channel blocker Substances 0.000 claims 1
- OIWOHHBRDFKZNC-UHFFFAOYSA-N cyclohexyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OC1CCCCC1 OIWOHHBRDFKZNC-UHFFFAOYSA-N 0.000 claims 1
- 239000003995 emulsifying agent Substances 0.000 claims 1
- 229960003133 ergot alkaloid Drugs 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 229960005309 estradiol Drugs 0.000 claims 1
- 229960003575 estradiol acetate Drugs 0.000 claims 1
- FHXBMXJMKMWVRG-SLHNCBLASA-N estradiol acetate Chemical compound C1C[C@]2(C)[C@@H](O)CC[C@H]2[C@@H]2CCC3=CC(OC(=O)C)=CC=C3[C@H]21 FHXBMXJMKMWVRG-SLHNCBLASA-N 0.000 claims 1
- 229940011871 estrogen Drugs 0.000 claims 1
- 239000000262 estrogen Substances 0.000 claims 1
- 229960002568 ethinylestradiol Drugs 0.000 claims 1
- SUPCQIBBMFXVTL-UHFFFAOYSA-N ethyl 2-methylprop-2-enoate Chemical compound CCOC(=O)C(C)=C SUPCQIBBMFXVTL-UHFFFAOYSA-N 0.000 claims 1
- VOZRXNHHFUQHIL-UHFFFAOYSA-N glycidyl methacrylate Chemical compound CC(=C)C(=O)OCC1CO1 VOZRXNHHFUQHIL-UHFFFAOYSA-N 0.000 claims 1
- 238000002657 hormone replacement therapy Methods 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- 229940119545 isobornyl methacrylate Drugs 0.000 claims 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 1
- 239000010410 layer Substances 0.000 claims 1
- 125000005395 methacrylic acid group Chemical group 0.000 claims 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 claims 1
- 229960002715 nicotine Drugs 0.000 claims 1
- 229940053934 norethindrone Drugs 0.000 claims 1
- 229960001652 norethindrone acetate Drugs 0.000 claims 1
- VIKNJXKGJWUCNN-XGXHKTLJSA-N norethisterone Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 VIKNJXKGJWUCNN-XGXHKTLJSA-N 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 229940049954 penicillin Drugs 0.000 claims 1
- 239000000106 platelet aggregation inhibitor Substances 0.000 claims 1
- 229920000058 polyacrylate Polymers 0.000 claims 1
- 239000000583 progesterone congener Substances 0.000 claims 1
- LYBIZMNPXTXVMV-UHFFFAOYSA-N propan-2-yl prop-2-enoate Chemical compound CC(C)OC(=O)C=C LYBIZMNPXTXVMV-UHFFFAOYSA-N 0.000 claims 1
- 239000011241 protective layer Substances 0.000 claims 1
- 239000012429 reaction media Substances 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
- SJMYWORNLPSJQO-UHFFFAOYSA-N tert-butyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OC(C)(C)C SJMYWORNLPSJQO-UHFFFAOYSA-N 0.000 claims 1
- ISXSCDLOGDJUNJ-UHFFFAOYSA-N tert-butyl prop-2-enoate Chemical compound CC(C)(C)OC(=O)C=C ISXSCDLOGDJUNJ-UHFFFAOYSA-N 0.000 claims 1
- 229960003604 testosterone Drugs 0.000 claims 1
- 229940124549 vasodilator Drugs 0.000 claims 1
- 239000003071 vasodilator agent Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10141652A DE10141652B4 (de) | 2001-08-24 | 2001-08-24 | Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung |
| PCT/EP2002/009057 WO2003017988A1 (de) | 2001-08-24 | 2002-08-13 | Transdermales therapeutisches system auf der basis von polyacrylat-haftklebern ohne funktionelle gruppen |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005503390A JP2005503390A (ja) | 2005-02-03 |
| JP2005503390A5 true JP2005503390A5 (https=) | 2006-01-05 |
| JP4393188B2 JP4393188B2 (ja) | 2010-01-06 |
Family
ID=7696570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003522508A Expired - Fee Related JP4393188B2 (ja) | 2001-08-24 | 2002-08-13 | 官能基を有しないポリアクリレート接触接着剤による経皮治療システム |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20040241219A1 (https=) |
| EP (1) | EP1418895B1 (https=) |
| JP (1) | JP4393188B2 (https=) |
| KR (1) | KR100920599B1 (https=) |
| CN (1) | CN1239153C (https=) |
| AU (1) | AU2002327831B2 (https=) |
| BR (1) | BRPI0211993B8 (https=) |
| CA (1) | CA2455064C (https=) |
| DE (1) | DE10141652B4 (https=) |
| ES (1) | ES2397920T3 (https=) |
| MX (1) | MXPA04001677A (https=) |
| WO (1) | WO2003017988A1 (https=) |
| ZA (1) | ZA200400312B (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002024157A2 (en) * | 2000-09-19 | 2002-03-28 | National Starch And Chemical Investment Holding Corporation | Acryl adhesive useful in transdermal drug delivery systems |
| DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| EP1648421B1 (en) * | 2003-07-24 | 2017-10-18 | GlaxoSmithKline LLC | Orally dissolving films |
| ES2395290T3 (es) * | 2004-04-13 | 2013-02-11 | Nipro Patch Co., Ltd. | Adhesivo piezosensible reticulable para la piel |
| CN1329022C (zh) * | 2004-08-31 | 2007-08-01 | 贵州太和制药有限公司 | 亲水性生物粘附凝胶贴剂及其制备工艺 |
| BRPI0607967B1 (pt) * | 2005-03-12 | 2022-07-19 | Unilever Ip Holdings B.V | Uso de visnadina |
| CN1320008C (zh) * | 2005-03-24 | 2007-06-06 | 上海交通大学 | 包含酯基部分带羧基基团的丙烯酸酯的组合物 |
| CN1326894C (zh) * | 2005-03-24 | 2007-07-18 | 上海交通大学 | 包含酯基部分带烷氧基的丙烯酸酯的组合物 |
| CN1320009C (zh) * | 2005-03-24 | 2007-06-06 | 上海交通大学 | 包含酯基部分带羟基基团的丙烯酸酯的组合物 |
| CN1320005C (zh) * | 2005-03-24 | 2007-06-06 | 上海交通大学 | 包含酯基部分带烷烃基的丙烯酸酯的组合物 |
| CN1320006C (zh) * | 2005-03-24 | 2007-06-06 | 上海交通大学 | 包含酯基部分带酯基基团的丙烯酸酯的组合物 |
| DE102006050558B4 (de) | 2006-10-26 | 2009-03-26 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System enthaltend Norelgestromin zur Kontrazeption und Hormonsubstitution |
| KR100956023B1 (ko) * | 2007-09-28 | 2010-05-06 | 대화제약 주식회사 | 산성 관능기를 갖는 아크릴레이트계 고분자의 함량으로약물 방출속도를 제어하는 툴로부테롤 경피 투여용 패취제 |
| DE102008013701A1 (de) * | 2008-03-11 | 2009-09-17 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System mit stabilisierter Membran |
| US20100087768A1 (en) * | 2008-10-02 | 2010-04-08 | Forlano Paula | Transdermal drug delivery system for liquid active ingredient |
| ES2670227T3 (es) | 2009-12-22 | 2018-05-29 | Luye Pharma Ag | Sistema terapéutico transdérmico para la administración de rivastigmina o sus derivados |
| US10076502B2 (en) | 2009-12-22 | 2018-09-18 | Luye Pharma Ag | Transdermal therapeutic system for administering rivastigmine or derivatives thereof |
| CN101967213A (zh) * | 2010-09-29 | 2011-02-09 | 北京化工大学 | 低分子量带有羧基的聚丙烯酸酯丙烯酸酯的制备方法 |
| DK2468274T3 (en) | 2010-12-14 | 2015-08-31 | Acino Ag | Transdermal therapeutic system for administration of an active substance |
| BR112014012444B1 (pt) | 2011-11-23 | 2021-12-14 | Therapeuticsmd, Inc | Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| JP6912876B2 (ja) * | 2016-10-06 | 2021-08-04 | 三洋化成工業株式会社 | アクリル系医薬固形製剤用添加剤 |
| DE102017115701B4 (de) * | 2017-07-12 | 2022-03-03 | Lts Lohmann Therapie-Systeme Ag | Fampridin-TTS |
| WO2019068288A1 (de) | 2017-10-04 | 2019-04-11 | Berlimed International Research Gmbh | Wirkstoff und wirkstoffmatrix enthaltendes produkt zur transdermalen wirkstoffabgabe sowie dessen herstellung und verwendung sowie die wirkstoffmatrix, ihre herstellung und verwendung |
| DE102018130469A1 (de) | 2018-11-30 | 2020-06-04 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit Diffusionsbarriere |
| DE102019120403A1 (de) | 2019-07-29 | 2021-02-04 | Lts Lohmann Therapie-Systeme Ag | Verfahren zur Herstellung von Haftklebemassen zur Verwendung in einem transdermalen therapeutischen System |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2693212B2 (ja) * | 1989-03-28 | 1997-12-24 | 日東電工株式会社 | 疾患治療用テープ製剤 |
| AU644815B2 (en) * | 1989-09-08 | 1993-12-23 | Ortho-Mcneil Pharmaceutical, Inc. | Solid matrix system for transdermal drug delivery |
| DE3933460A1 (de) * | 1989-10-06 | 1991-04-18 | Lohmann Therapie Syst Lts | Oestrogenhaltiges wirkstoffpflaster |
| CA2039586A1 (en) * | 1990-05-02 | 1991-11-03 | Marian R. Appelt | Crosslinked pressure-sensitive adhesives tolerant of alcohol-based excipients used in transdermal delivery devices and method of preparing same |
| IT1253265B (it) * | 1991-11-25 | 1995-07-14 | Rotta Research Lab | Preparato a matrice copolimerica adesiva a base acrilica per il rilascio transdermico dell'estradiolo. |
| FI942425L (fi) * | 1991-11-26 | 1994-05-25 | Res Dev Foundation | Sikiökalvoista tehtyjä putkia hermo- ja verisuonisiirteitä varten |
| DE4301783C1 (de) * | 1993-01-23 | 1994-02-03 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit Galanthamin als wirksamem Bestandteil |
| DE4310012A1 (de) * | 1993-03-27 | 1994-09-29 | Roehm Gmbh | Dermales therapeutisches System aus einer schmelzfähigen Poly(meth)acrylat-Mischung |
| WO1994023707A1 (de) * | 1993-04-20 | 1994-10-27 | Hexal Pharma Gmbh | Wirkstoffplaster |
| US5804214A (en) * | 1993-07-08 | 1998-09-08 | Cygnus, Inc. | Monolithic matrix transdermal delivery system for delivering ketorolac tromethamine |
| US5554381A (en) * | 1993-08-09 | 1996-09-10 | Cygnus, Inc. | Low flux matrix system for delivering potent drugs transdermally |
| EP0661046B1 (en) * | 1993-12-30 | 1998-09-30 | Rotta Research B.V. | Transdermal patch with isosorbide dinitrate as active ingredient |
| DE4403487C2 (de) * | 1994-02-04 | 2003-10-16 | Lohmann Therapie Syst Lts | Arznei-Pflaster mit UV-vernetzbaren Acrylat-Copolymeren |
| US5614210A (en) * | 1995-03-31 | 1997-03-25 | Minnesota Mining And Manufacturing Company | Transdermal device for the delivery of alfuzosin |
| SE504430C2 (sv) | 1995-06-20 | 1997-02-10 | Ericsson Telefon Ab L M | Magasin |
| JPH1036265A (ja) * | 1996-07-19 | 1998-02-10 | Nitto Denko Corp | ブプレノルフィン経皮吸収製剤 |
| US5928666A (en) * | 1996-11-12 | 1999-07-27 | Cygnus Inc. | Crystalline form of estradiol and pharmaceutical formulations comprising same |
| US6210705B1 (en) * | 1997-12-15 | 2001-04-03 | Noven Pharmaceuticals, Nc. | Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
| DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| DE19830651A1 (de) * | 1998-07-09 | 2000-01-13 | Lohmann Therapie Syst Lts | Steroidhaltiges Pflaster, Verfahren zu seiner Herstellung und Verwendung |
| ATE288256T1 (de) * | 1999-01-14 | 2005-02-15 | Noven Pharma | Dermale zusammensetzungen |
| ATE287711T1 (de) | 1999-11-29 | 2005-02-15 | Novosis Ag | Transdermalsystem zur abgabe von clonidin |
| DE10032537A1 (de) * | 2000-07-05 | 2002-01-31 | Labtec Gmbh | Dermales System, enthaltend 2-(3-Benzophenyl)Propionsäure |
| WO2002024157A2 (en) * | 2000-09-19 | 2002-03-28 | National Starch And Chemical Investment Holding Corporation | Acryl adhesive useful in transdermal drug delivery systems |
-
2001
- 2001-08-24 DE DE10141652A patent/DE10141652B4/de not_active Expired - Lifetime
-
2002
- 2002-08-13 KR KR1020047002667A patent/KR100920599B1/ko not_active Expired - Fee Related
- 2002-08-13 US US10/487,380 patent/US20040241219A1/en not_active Abandoned
- 2002-08-13 CN CNB028164385A patent/CN1239153C/zh not_active Expired - Fee Related
- 2002-08-13 BR BRPI0211993A patent/BRPI0211993B8/pt not_active IP Right Cessation
- 2002-08-13 JP JP2003522508A patent/JP4393188B2/ja not_active Expired - Fee Related
- 2002-08-13 CA CA2455064A patent/CA2455064C/en not_active Expired - Lifetime
- 2002-08-13 EP EP02762444A patent/EP1418895B1/de not_active Revoked
- 2002-08-13 ES ES02762444T patent/ES2397920T3/es not_active Expired - Lifetime
- 2002-08-13 AU AU2002327831A patent/AU2002327831B2/en not_active Ceased
- 2002-08-13 MX MXPA04001677A patent/MXPA04001677A/es active IP Right Grant
- 2002-08-13 WO PCT/EP2002/009057 patent/WO2003017988A1/de not_active Ceased
-
2004
- 2004-01-15 ZA ZA200400312A patent/ZA200400312B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2005503390A5 (https=) | ||
| CA2455064A1 (en) | Transdermal therapeutic system based on polyacrylate contact adhesives without functional groups | |
| CN1188189C (zh) | 基质层含有17－脱乙酰基诺孕酯的经皮贴片及基质的用途 | |
| US5693335A (en) | Skin permeation enhancer composition for use with sex steroids | |
| JP6689254B2 (ja) | 経皮薬物送達組成物のためのシリコーン含有アクリルポリマー | |
| JP2007509951A5 (https=) | ||
| KR101892764B1 (ko) | 경피 접착제 조성물, 디바이스, 및 방법 | |
| JP2849950B2 (ja) | 経皮吸収製剤 | |
| WO2007094385A1 (ja) | 凝集力向上及び徐放化の外用貼付剤 | |
| JP2004514738A (ja) | 活性物質としてオキシブチニンで構成される経皮治療システム | |
| NZ524767A (en) | Composition for the transdermal delivery of fentanyl | |
| CN1901861A (zh) | 透皮递药装置 | |
| CN1303986C (zh) | 贴剂 | |
| RU2008138595A (ru) | Гибкая ограниченная система для трансдермального введения скополамина, способ ее изготовления и способ трансдермальной доставки скополамина с ее помощью | |
| WO2007099966A1 (ja) | 経皮吸収型製剤 | |
| JP5016309B2 (ja) | 医療用テープ剤 | |
| RU2003129636A (ru) | Обладающая высокой гибкостью трансдермальная терапевтическая система с никотином в качестве активного вещества | |
| JP3361674B2 (ja) | 医療用粘着剤組成物 | |
| JP2967788B2 (ja) | 医療用粘着テープおよび疾患治療用テープ製剤 | |
| JP4311728B2 (ja) | 経皮吸収型貼付剤 | |
| JP3618970B2 (ja) | 貼付剤 | |
| WO2007023791A1 (ja) | 外用剤 | |
| EP1802665B1 (en) | Method for the manufacture of pressure sensitive adhesives | |
| JPS6126967B2 (https=) | ||
| AU2002247331C1 (en) | Transdermal patch for administering fentanyl |