JP2005195485A5 - - Google Patents

Download PDF

Info

Publication number
JP2005195485A5
JP2005195485A5 JP2004002886A JP2004002886A JP2005195485A5 JP 2005195485 A5 JP2005195485 A5 JP 2005195485A5 JP 2004002886 A JP2004002886 A JP 2004002886A JP 2004002886 A JP2004002886 A JP 2004002886A JP 2005195485 A5 JP2005195485 A5 JP 2005195485A5
Authority
JP
Japan
Prior art keywords
light source
confocal
semiconductor
excitation
fluorescence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2004002886A
Other languages
English (en)
Japanese (ja)
Other versions
JP4414771B2 (ja
JP2005195485A (ja
Filing date
Publication date
Application filed filed Critical
Priority to JP2004002886A priority Critical patent/JP4414771B2/ja
Priority claimed from JP2004002886A external-priority patent/JP4414771B2/ja
Priority to US11/020,456 priority patent/US7315039B2/en
Publication of JP2005195485A publication Critical patent/JP2005195485A/ja
Publication of JP2005195485A5 publication Critical patent/JP2005195485A5/ja
Application granted granted Critical
Publication of JP4414771B2 publication Critical patent/JP4414771B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2004002886A 2004-01-08 2004-01-08 共焦点顕微分光装置 Expired - Fee Related JP4414771B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2004002886A JP4414771B2 (ja) 2004-01-08 2004-01-08 共焦点顕微分光装置
US11/020,456 US7315039B2 (en) 2004-01-08 2004-12-22 Confocal microspectroscope

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2004002886A JP4414771B2 (ja) 2004-01-08 2004-01-08 共焦点顕微分光装置

Publications (3)

Publication Number Publication Date
JP2005195485A JP2005195485A (ja) 2005-07-21
JP2005195485A5 true JP2005195485A5 (https=) 2007-02-22
JP4414771B2 JP4414771B2 (ja) 2010-02-10

Family

ID=34737131

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004002886A Expired - Fee Related JP4414771B2 (ja) 2004-01-08 2004-01-08 共焦点顕微分光装置

Country Status (2)

Country Link
US (1) US7315039B2 (https=)
JP (1) JP4414771B2 (https=)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60141090D1 (de) 2000-10-30 2010-03-04 Gen Hospital Corp Optische systeme zur gewebeanalyse
CA2519937C (en) 2003-03-31 2012-11-20 Guillermo J. Tearney Speckle reduction in optical coherence tomography by path length encoded angular compounding
EP2280260B1 (en) 2003-06-06 2017-03-08 The General Hospital Corporation Process and apparatus for a wavelength tuned light source
AU2005270037B2 (en) 2004-07-02 2012-02-09 The General Hospital Corporation Endoscopic imaging probe comprising dual clad fibre
WO2006024015A1 (en) 2004-08-24 2006-03-02 The General Hospital Corporation Method and apparatus for imaging of vessel segments
WO2006024014A2 (en) 2004-08-24 2006-03-02 The General Hospital Corporation Process, system and software arrangement for measuring a mechanical strain and elastic properties of a sample
US8922781B2 (en) 2004-11-29 2014-12-30 The General Hospital Corporation Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample
EP2085929A1 (en) 2005-04-28 2009-08-05 The General Hospital Corporation Evaluating optical coherence tomography information for an anatomical structure
EP1889037A2 (en) 2005-06-01 2008-02-20 The General Hospital Corporation Apparatus, method and system for performing phase-resolved optical frequency domain imaging
ATE484727T1 (de) 2005-08-09 2010-10-15 Gen Hospital Corp Gerät und verfahren zur durchführung von polarisationsbasierter quadraturdemodulation bei optischer kohärenztomographie
AU2006299659A1 (en) 2005-09-29 2007-04-12 General Hospital Corporation Method and apparatus for method for viewing and analyzing of one or more biological samples with progressively increasing resolutions
US7889348B2 (en) * 2005-10-14 2011-02-15 The General Hospital Corporation Arrangements and methods for facilitating photoluminescence imaging
US8145018B2 (en) 2006-01-19 2012-03-27 The General Hospital Corporation Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and methods for producing one or more optical arrangements
ES2847854T3 (es) 2006-01-19 2021-08-04 Massachusetts Gen Hospital Catéter de globo de obtención de imágenes
EP1983921B1 (en) 2006-02-01 2016-05-25 The General Hospital Corporation Systems for providing electromagnetic radiation to at least one portion of a sample using conformal laser therapy procedures
US7538859B2 (en) 2006-02-01 2009-05-26 The General Hospital Corporation Methods and systems for monitoring and obtaining information of at least one portion of a sample using conformal laser therapy procedures, and providing electromagnetic radiation thereto
JP2007225381A (ja) * 2006-02-22 2007-09-06 Osaka Prefecture Univ 蛍光測定方法及び蛍光顕微鏡
US7982879B2 (en) 2006-02-24 2011-07-19 The General Hospital Corporation Methods and systems for performing angle-resolved fourier-domain optical coherence tomography
EP3150110B1 (en) 2006-05-10 2020-09-02 The General Hospital Corporation Processes, arrangements and systems for providing frequency domain imaging of a sample
US7846391B2 (en) 2006-05-22 2010-12-07 Lumencor, Inc. Bioanalytical instrumentation using a light source subsystem
US8838213B2 (en) 2006-10-19 2014-09-16 The General Hospital Corporation Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample, and effecting such portion(s)
DE102007003134A1 (de) * 2007-01-18 2008-07-24 Carl Zeiss Microimaging Gmbh Laserscanmikroskop und strahlvereinigende optische Baugruppe
EP2602651A3 (en) 2007-03-23 2014-08-27 The General Hospital Corporation Methods, arrangements and apparatus for utilizing a wavelength-swept laser using angular scanning and dispersion procedures
WO2008121844A1 (en) 2007-03-30 2008-10-09 The General Hospital Corporation System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque
US8098375B2 (en) 2007-08-06 2012-01-17 Lumencor, Inc. Light emitting diode illumination system
WO2010009136A2 (en) 2008-07-14 2010-01-21 The General Hospital Corporation Apparatus and methods for color endoscopy
KR101018153B1 (ko) * 2008-11-27 2011-02-28 삼성엘이디 주식회사 Led 패키지
ES2957932T3 (es) 2008-12-10 2024-01-30 Massachusetts Gen Hospital Sistemas, aparatos y procedimientos para ampliar el rango de profundidad de imagen de tomografía de coherencia óptica mediante submuestreo óptico
JP2012515576A (ja) 2009-01-20 2012-07-12 ザ ジェネラル ホスピタル コーポレイション 内視鏡生検装置、システム、及び方法
US8242462B2 (en) 2009-01-23 2012-08-14 Lumencor, Inc. Lighting design of high quality biomedical devices
CN104134928A (zh) 2009-02-04 2014-11-05 通用医疗公司 利用高速光学波长调谐源的设备和方法
US11490826B2 (en) 2009-07-14 2022-11-08 The General Hospital Corporation Apparatus, systems and methods for measuring flow and pressure within a vessel
HRP20201813T1 (hr) 2010-03-05 2021-03-19 The General Hospital Corporation Uređaj za pružanje elektromagnetnog zračenja na uzorak
US9069130B2 (en) 2010-05-03 2015-06-30 The General Hospital Corporation Apparatus, method and system for generating optical radiation from biological gain media
EP2575597B1 (en) 2010-05-25 2022-05-04 The General Hospital Corporation Apparatus for providing optical imaging of structures and compositions
WO2011150069A2 (en) 2010-05-25 2011-12-01 The General Hospital Corporation Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images
WO2011153434A2 (en) 2010-06-03 2011-12-08 The General Hospital Corporation Apparatus and method for devices for imaging structures in or at one or more luminal organs
EP2632324A4 (en) 2010-10-27 2015-04-22 Gen Hospital Corp DEVICES, SYSTEMS AND METHOD FOR MEASURING BLOOD PRESSURE IN AT LEAST ONE VESSEL
US8389957B2 (en) 2011-01-14 2013-03-05 Lumencor, Inc. System and method for metered dosage illumination in a bioanalysis or other system
US8466436B2 (en) 2011-01-14 2013-06-18 Lumencor, Inc. System and method for metered dosage illumination in a bioanalysis or other system
CN102175643B (zh) * 2011-03-18 2013-04-10 苏州晓松科技开发有限公司 激光物证勘查仪
JP2014523536A (ja) 2011-07-19 2014-09-11 ザ ジェネラル ホスピタル コーポレイション 光コヒーレンストモグラフィーにおいて偏波モード分散補償を提供するためのシステム、方法、装置およびコンピュータアクセス可能な媒体
TWI454735B (zh) * 2011-08-19 2014-10-01 Anmo Electronics Corp 手持式螢光顯微鏡
US9341783B2 (en) 2011-10-18 2016-05-17 The General Hospital Corporation Apparatus and methods for producing and/or providing recirculating optical delay(s)
US8967811B2 (en) 2012-01-20 2015-03-03 Lumencor, Inc. Solid state continuous white light source
US9629528B2 (en) 2012-03-30 2017-04-25 The General Hospital Corporation Imaging system, method and distal attachment for multidirectional field of view endoscopy
EP2852315A4 (en) 2012-05-21 2016-06-08 Gen Hospital Corp DEVICE, APPARATUS AND METHOD FOR CAPSULE MICROSCOPY
US9217561B2 (en) 2012-06-15 2015-12-22 Lumencor, Inc. Solid state light source for photocuring
JP6227652B2 (ja) 2012-08-22 2017-11-08 ザ ジェネラル ホスピタル コーポレイション ソフトリソグラフィを用いてミニチュア内視鏡を製作するためのシステム、方法、およびコンピュータ・アクセス可能媒体
US10101274B2 (en) 2012-12-05 2018-10-16 Genepoc Inc. Optical interrogation device
JP2014115121A (ja) * 2012-12-06 2014-06-26 Sony Corp 微小粒子分析装置及び微小粒子分析方法
EP2948758B1 (en) 2013-01-28 2024-03-13 The General Hospital Corporation Apparatus for providing diffuse spectroscopy co-registered with optical frequency domain imaging
US10893806B2 (en) 2013-01-29 2021-01-19 The General Hospital Corporation Apparatus, systems and methods for providing information regarding the aortic valve
WO2014121082A1 (en) 2013-02-01 2014-08-07 The General Hospital Corporation Objective lens arrangement for confocal endomicroscopy
WO2014144709A2 (en) 2013-03-15 2014-09-18 The General Hospital Corporation Methods and systems for characterizing an object
US9784681B2 (en) 2013-05-13 2017-10-10 The General Hospital Corporation System and method for efficient detection of the phase and amplitude of a periodic modulation associated with self-interfering fluorescence
EP3692887B1 (en) 2013-07-19 2024-03-06 The General Hospital Corporation Imaging apparatus which utilizes multidirectional field of view endoscopy
EP3021735A4 (en) 2013-07-19 2017-04-19 The General Hospital Corporation Determining eye motion by imaging retina. with feedback
EP3910282B1 (en) 2013-07-26 2024-01-17 The General Hospital Corporation Method of providing a laser radiation with a laser arrangement utilizing optical dispersion for applications in fourier-domain optical coherence tomography
CN104076001A (zh) * 2013-12-17 2014-10-01 浙江工商大学 基于激光器阵列的检测装置及大黄鱼存储时间检测方法
CN104089883B (zh) * 2013-12-17 2017-02-01 浙江工商大学 基于激光器阵列的检测装置及小黄鱼存储时间检测方法
US9733460B2 (en) 2014-01-08 2017-08-15 The General Hospital Corporation Method and apparatus for microscopic imaging
US10736494B2 (en) 2014-01-31 2020-08-11 The General Hospital Corporation System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device
US10228556B2 (en) 2014-04-04 2019-03-12 The General Hospital Corporation Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s)
US10912462B2 (en) 2014-07-25 2021-02-09 The General Hospital Corporation Apparatus, devices and methods for in vivo imaging and diagnosis
LU92620B1 (de) * 2014-12-19 2016-06-20 Leica Microsystems Rastermikroskop
CN104597590B (zh) * 2014-12-30 2018-02-02 深圳先进技术研究院 一种超分辨荧光光谱成像显微镜
CN106990519B (zh) * 2017-05-12 2024-09-24 中国科学院苏州生物医学工程技术研究所 结构光照明显微成像系统
US10837908B2 (en) * 2018-04-20 2020-11-17 The Procter And Gamble Company Spatial imaging of scalp care agents
US11525967B1 (en) 2018-09-28 2022-12-13 Apple Inc. Photonics integrated circuit architecture
CN113873986B (zh) 2019-06-28 2024-04-26 宝洁公司 提高吡啶硫酮锌在诸如头皮皮脂流体的氧化环境中的稳定性
US11881678B1 (en) 2019-09-09 2024-01-23 Apple Inc. Photonics assembly with a photonics die stack
US12218479B2 (en) 2020-07-20 2025-02-04 Apple Inc. Photonic integrated circuits with controlled collapse chip connections
US20230011177A1 (en) * 2021-07-08 2023-01-12 Apple Inc. Light Source Modules for Noise Mitigation
US11914201B2 (en) 2021-09-23 2024-02-27 Apple Inc. Mechanisms that transfer light between layers of multi-chip photonic assemblies
US12111207B2 (en) 2022-09-23 2024-10-08 Apple Inc. Despeckling in optical measurement systems

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5239178A (en) * 1990-11-10 1993-08-24 Carl Zeiss Optical device with an illuminating grid and detector grid arranged confocally to an object
JPH0894938A (ja) * 1994-09-21 1996-04-12 Sony Corp 共焦点顕微鏡並びに光記録再生装置
JP3816632B2 (ja) * 1997-05-14 2006-08-30 オリンパス株式会社 走査型顕微鏡
US6121603A (en) * 1997-12-01 2000-09-19 Hang; Zhijiang Optical confocal device having a common light directing means
US6355934B1 (en) * 1999-02-26 2002-03-12 Packard Biochip Technologies Imaging system for an optical scanner
US6181474B1 (en) * 1999-03-22 2001-01-30 Kovex Corporation Scanning confocal microscope with objective lens position tracking
JP2001185796A (ja) * 1999-12-27 2001-07-06 Hitachi Metals Ltd レーザ装置、その応用装置並びにその使用方法
US6423956B1 (en) * 2000-07-28 2002-07-23 Optical Biopsy Technologies Fiber-coupled, high-speed, integrated, angled-dual-axis confocal scanning microscopes employing vertical cross-section scanning
US6858852B2 (en) * 2000-08-08 2005-02-22 Carl Zeiss Jena Gmbh Method and apparatus for rapid change of fluorescence bands in the detection of dyes in fluorescence microscopy
DE10038526B4 (de) 2000-08-08 2004-09-02 Carl Zeiss Jena Gmbh Verfahren und Anordnung zur Erfassung des wellenlängenabhängigen Verhaltens einer beleuchteten Probe
US6987259B2 (en) * 2002-05-30 2006-01-17 Dmetrix, Inc. Imaging system with an integrated source and detector array
US20050053109A1 (en) * 2002-06-03 2005-03-10 Josh Hogan Integrated multiple wavelength system
DE10225838B4 (de) * 2002-06-11 2021-10-21 Leica Microsystems Cms Gmbh Verfahren zur Scanmikroskopie, Scanmikroskop und Vorrichtung zum Codieren eines Beleuchtungslichtstrahles
US6985224B2 (en) * 2003-03-14 2006-01-10 The United States Of America As Represented By The Secretary Of The Navy Light emitting diode (LED) array for excitation emission matrix (EEM) fluorescence spectroscopy
US7215468B2 (en) * 2003-07-29 2007-05-08 Olympus Corporation Confocal microscope

Similar Documents

Publication Publication Date Title
JP2005195485A5 (https=)
US8199332B2 (en) Apparatus for measuring thickness
US11560591B2 (en) Analytic device comprising a substrate, nanometer-scale wells, and shallow waveguide optically coupled to a deep waveguide
JP4414771B2 (ja) 共焦点顕微分光装置
JP5859527B2 (ja) 測光において使用可能なダイナミックレンジの拡大
US20100321696A1 (en) Optical devices and methods for measuring samples
JP2007171186A (ja) 試料検出システム
TWI619936B (zh) 用於樣本之偵測裝置
JP2012515928A (ja) 高品質生物医学装置の照明設計
JP2008539447A5 (https=)
US10175171B2 (en) Compact multi-UV-LED probe system and methods of use thereof
KR20030037314A (ko) 바이오 칩 분석을 위한 형광 영상 분석장치
EP3189325B1 (en) Method and apparatus for optical measurement of a liquid sample
JPWO2004038350A1 (ja) 光源ユニット、受光ユニット及びこれらを用いたマルチチャンネル光検出装置
JP2008512666A (ja) 増幅発光近接均質解析(AmplifiedLuminescentProximityHomogeneousAssay)の光学的測定に適合する器具類および方法
US8581211B2 (en) Imaging method and system using substrate functionalization
CN106404727B (zh) 感测模块及感测方法
US7862218B2 (en) Point source apparatus and method of manufacture thereof
US11047799B2 (en) Device and method for providing illumination for total-internal-reflection fluorescence microscopy using opaque mask
RU2280247C1 (ru) Биочип для флуоресцентного и люминесцентного анализа
Chaudhery et al. Photobleaching on photonic crystal enhanced fluorescence surfaces
US20130056620A1 (en) Device for lighting an object, with light source provided with a member for sampling a portion of said light, application to the measurement of flux variations of the source
KR20180028592A (ko) 다중 조명계를 포함하는 광분석기
JP2006242902A (ja) バイオセンシング装置
WO2017105273A1 (ru) Анализатор состава жидких и твердых веществ