JP2005096866A - 少量の液体を取出し可能に貯留するための微細構造装置および該装置に貯留された液体の取出し方法 - Google Patents

少量の液体を取出し可能に貯留するための微細構造装置および該装置に貯留された液体の取出し方法 Download PDF

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Publication number
JP2005096866A
JP2005096866A JP2004278569A JP2004278569A JP2005096866A JP 2005096866 A JP2005096866 A JP 2005096866A JP 2004278569 A JP2004278569 A JP 2004278569A JP 2004278569 A JP2004278569 A JP 2004278569A JP 2005096866 A JP2005096866 A JP 2005096866A
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JP
Japan
Prior art keywords
blocking element
hollow chamber
microstructure device
carrier
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
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JP2004278569A
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English (en)
Japanese (ja)
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JP2005096866A5 (https=
Inventor
Gert Blankenstein
ブランケンシュタイン,ゲルト
Klaus Kadel
カーデル,クラウス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Microparts GmbH
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Steag Microparts GmbH
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Publication date
Application filed by Steag Microparts GmbH filed Critical Steag Microparts GmbH
Publication of JP2005096866A publication Critical patent/JP2005096866A/ja
Publication of JP2005096866A5 publication Critical patent/JP2005096866A5/ja
Withdrawn legal-status Critical Current

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    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K99/0001Microvalves
    • F16K99/0003Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0017Capillary or surface tension valves, e.g. using electro-wetting or electro-capillarity effects
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K99/0001Microvalves
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K99/0001Microvalves
    • F16K99/0003Constructional types of microvalves; Details of the cutting-off member
    • F16K99/003Valves for single use only
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K99/0001Microvalves
    • F16K99/0034Operating means specially adapted for microvalves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16Reagents, handling or storing thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/044Connecting closures to device or container pierceable, e.g. films, membranes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/046Function or devices integrated in the closure
    • B01L2300/047Additional chamber, reservoir
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0672Integrated piercing tool
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • B01L2400/0638Valves, specific forms thereof with moving parts membrane valves, flap valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • B01L2400/065Valves, specific forms thereof with moving parts sliding valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Rigid containers without fluid transport within
    • B01L3/5085Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52Containers specially adapted for storing or dispensing a reagent
    • B01L3/523Containers specially adapted for storing or dispensing a reagent with means for closing or opening
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575Volumetric liquid transfer

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  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Closures For Containers (AREA)
JP2004278569A 2003-09-24 2004-09-24 少量の液体を取出し可能に貯留するための微細構造装置および該装置に貯留された液体の取出し方法 Withdrawn JP2005096866A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10344229A DE10344229A1 (de) 2003-09-24 2003-09-24 Mikrostruktuierte Vorrichtung zum entnehmbaren Speichern von kleinen Flüssigkeitsmengen und Verfahren zum Entnehmen der in dieser Vorrichtung gespeicherten Flüssigkeit

Publications (2)

Publication Number Publication Date
JP2005096866A true JP2005096866A (ja) 2005-04-14
JP2005096866A5 JP2005096866A5 (https=) 2007-11-01

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JP2004278569A Withdrawn JP2005096866A (ja) 2003-09-24 2004-09-24 少量の液体を取出し可能に貯留するための微細構造装置および該装置に貯留された液体の取出し方法

Country Status (5)

Country Link
US (2) US20050093087A1 (https=)
EP (1) EP1518604B1 (https=)
JP (1) JP2005096866A (https=)
CN (1) CN100467128C (https=)
DE (1) DE10344229A1 (https=)

Cited By (9)

* Cited by examiner, † Cited by third party
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JPWO2013042435A1 (ja) * 2011-09-20 2015-03-26 富士紡ホールディングス株式会社 試薬容器
JP2015211728A (ja) * 2014-05-01 2015-11-26 株式会社タスコ 宝石
WO2016175229A1 (ja) * 2015-04-30 2016-11-03 シスメックス株式会社 液体封止カートリッジ、検体分析装置、および、検体分析方法
JPWO2015045134A1 (ja) * 2013-09-30 2017-03-02 株式会社日立製作所 試薬保持容器、送液装置、試薬吐出方法
WO2018051880A1 (ja) * 2016-09-14 2018-03-22 積水化学工業株式会社 マイクロチップ
JP2018072131A (ja) * 2016-10-28 2018-05-10 シスメックス株式会社 液体封止カートリッジおよび送液方法
WO2020158712A1 (ja) * 2019-02-01 2020-08-06 株式会社エンプラス 流体取扱システムおよびカートリッジ
KR20210022662A (ko) * 2018-09-11 2021-03-03 에프. 호프만-라 로슈 아게 액체 팩을 갖는 카트리지
EP3798000A1 (en) 2019-09-27 2021-03-31 Sysmex Corporation Liquid-sealed cartridge and liquid sending method

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JP6116490B2 (ja) * 2011-03-09 2017-04-19 ピクセル メディカル テクノロジーズ リミテッド 分析対象の細胞を含む試料流体の調製に用いる使い捨てカートリッジ
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JPWO2013042435A1 (ja) * 2011-09-20 2015-03-26 富士紡ホールディングス株式会社 試薬容器
JPWO2015045134A1 (ja) * 2013-09-30 2017-03-02 株式会社日立製作所 試薬保持容器、送液装置、試薬吐出方法
JP2015211728A (ja) * 2014-05-01 2015-11-26 株式会社タスコ 宝石
US10697989B2 (en) 2015-04-30 2020-06-30 Sysmex Corporation Liquid-sealed cartridge, specimen analyzer, and specimen analysis method
WO2016175229A1 (ja) * 2015-04-30 2016-11-03 シスメックス株式会社 液体封止カートリッジ、検体分析装置、および、検体分析方法
JPWO2016175229A1 (ja) * 2015-04-30 2018-02-22 シスメックス株式会社 液体封止カートリッジ、検体分析装置、および、検体分析方法
WO2018051880A1 (ja) * 2016-09-14 2018-03-22 積水化学工業株式会社 マイクロチップ
JPWO2018051880A1 (ja) * 2016-09-14 2018-09-13 積水化学工業株式会社 マイクロチップ
US11117135B2 (en) 2016-10-28 2021-09-14 Sysmex Corporation Liquid-sealed cartridge and liquid transferring method
JP2018072131A (ja) * 2016-10-28 2018-05-10 シスメックス株式会社 液体封止カートリッジおよび送液方法
KR20210022662A (ko) * 2018-09-11 2021-03-03 에프. 호프만-라 로슈 아게 액체 팩을 갖는 카트리지
KR102685230B1 (ko) * 2018-09-11 2024-07-15 에프. 호프만-라 로슈 아게 액체 팩을 갖는 카트리지
US12042795B2 (en) 2018-09-11 2024-07-23 Roche Diagnostics Operations, Inc. Cartridge with liquid pack
WO2020158712A1 (ja) * 2019-02-01 2020-08-06 株式会社エンプラス 流体取扱システムおよびカートリッジ
EP3798000A1 (en) 2019-09-27 2021-03-31 Sysmex Corporation Liquid-sealed cartridge and liquid sending method
JP2021056010A (ja) * 2019-09-27 2021-04-08 シスメックス株式会社 液体封止カートリッジおよび送液方法
US11433680B2 (en) 2019-09-27 2022-09-06 Sysmex Corporation Liquid-sealed cartridge and liquid sending method
JP7445403B2 (ja) 2019-09-27 2024-03-07 シスメックス株式会社 液体封止カートリッジおよび送液方法

Also Published As

Publication number Publication date
EP1518604A2 (de) 2005-03-30
DE10344229A1 (de) 2005-05-19
CN100467128C (zh) 2009-03-11
US20090074626A1 (en) 2009-03-19
CN1608735A (zh) 2005-04-27
EP1518604A3 (de) 2009-07-01
US7964161B2 (en) 2011-06-21
US20050093087A1 (en) 2005-05-05
EP1518604B1 (de) 2018-06-13

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