JP2004537597A5 - - Google Patents
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- Publication number
- JP2004537597A5 JP2004537597A5 JP2003519029A JP2003519029A JP2004537597A5 JP 2004537597 A5 JP2004537597 A5 JP 2004537597A5 JP 2003519029 A JP2003519029 A JP 2003519029A JP 2003519029 A JP2003519029 A JP 2003519029A JP 2004537597 A5 JP2004537597 A5 JP 2004537597A5
- Authority
- JP
- Japan
- Prior art keywords
- flibanserin
- polymorph
- disease
- mixture
- disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *CCN(CC1)CCN1c1cccc(C(F)(F)F)c1 Chemical compound *CCN(CC1)CCN1c1cccc(C(F)(F)F)c1 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01118593 | 2001-08-02 | ||
| EP01130180 | 2001-12-19 | ||
| PCT/EP2002/008466 WO2003014079A1 (en) | 2001-08-02 | 2002-07-30 | Stable polymorph of flibanserin, technical process for its preparation and the use thereof for preparing medicaments |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004537597A JP2004537597A (ja) | 2004-12-16 |
| JP2004537597A5 true JP2004537597A5 (enExample) | 2006-02-16 |
| JP3822601B2 JP3822601B2 (ja) | 2006-09-20 |
Family
ID=26076670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003519029A Expired - Fee Related JP3822601B2 (ja) | 2001-08-02 | 2002-07-30 | 安定多形体のフリバンセリン、その製造方法及び薬剤を製造するためのその使用 |
Country Status (26)
| Country | Link |
|---|---|
| EP (2) | EP1414816B1 (enExample) |
| JP (1) | JP3822601B2 (enExample) |
| KR (1) | KR100899297B1 (enExample) |
| CN (1) | CN1288147C (enExample) |
| AR (2) | AR036208A1 (enExample) |
| AT (1) | ATE288911T1 (enExample) |
| AU (1) | AU2002331361B2 (enExample) |
| BR (1) | BR0211601A (enExample) |
| CA (1) | CA2450093C (enExample) |
| CO (1) | CO5560572A2 (enExample) |
| DE (1) | DE60202958T2 (enExample) |
| DK (1) | DK1414816T3 (enExample) |
| EA (1) | EA006400B1 (enExample) |
| ES (1) | ES2237694T3 (enExample) |
| HR (1) | HRP20040107B1 (enExample) |
| HU (1) | HU228666B1 (enExample) |
| IL (2) | IL159151A0 (enExample) |
| MX (1) | MXPA04000913A (enExample) |
| MY (1) | MY127294A (enExample) |
| NZ (1) | NZ530510A (enExample) |
| PL (1) | PL210224B1 (enExample) |
| PT (1) | PT1414816E (enExample) |
| RS (1) | RS50742B (enExample) |
| SI (1) | SI1414816T1 (enExample) |
| UA (1) | UA76767C2 (enExample) |
| WO (1) | WO2003014079A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7183410B2 (en) | 2001-08-02 | 2007-02-27 | Bidachem S.P.A. | Stable polymorph of flibanserin |
| DE10138273A1 (de) * | 2001-08-10 | 2003-02-27 | Boehringer Ingelheim Pharma | Arzneimittel mit neuroprotektiver Wirkung |
| US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
| UA78974C2 (en) | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
| RS51718B (sr) * | 2002-05-22 | 2011-10-31 | Boehringer Ingelheim Pharma Gmbh. & Co.Kg. | Nove farmaceutske kompozicije koje sadrže flibanserin polimorf a |
| CA2608249A1 (en) * | 2005-05-06 | 2006-11-16 | Boehringer Ingelheim International Gmbh | Method for the treatment of drug abuse with flibanserin |
| EP1912650B8 (en) | 2005-08-03 | 2017-10-18 | Sprout Pharmaceuticals, Inc. | Use of flibanserin in the treatment of obesity |
| EP1945214A1 (en) | 2005-10-29 | 2008-07-23 | Boehringer Ingelheim International GmbH | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
| US20070105869A1 (en) * | 2005-11-08 | 2007-05-10 | Stephane Pollentier | Use of flibanserin for the treatment of pre-menopausal sexual desire disorders |
| CA2642368A1 (en) * | 2006-02-28 | 2007-09-07 | Boehringer Ingelheim International Gmbh | Treatment of prevention of valvular heart disease with flibanserin |
| PT2021006E (pt) * | 2006-05-09 | 2015-11-12 | Sprout Pharmaceuticals Inc | Uso de flibanserina para o tratamento de distúrbios de desejo sexual pós-menopausa |
| JP2009541443A (ja) | 2006-06-30 | 2009-11-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 尿失禁及び関連疾患の治療のためのフリバンセリン |
| CL2007002214A1 (es) | 2006-08-14 | 2008-03-07 | Boehringer Ingelheim Int | Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp |
| KR20090042967A (ko) | 2006-08-14 | 2009-05-04 | 베링거 인겔하임 인터내셔날 게엠베하 | 플리반세린 제형 및 이의 제조방법 |
| CN104721168A (zh) | 2006-08-25 | 2015-06-24 | 贝林格尔·英格海姆国际有限公司 | 控制释放系统及其制造方法 |
| WO2008061966A2 (en) * | 2006-11-22 | 2008-05-29 | Boehringer Ingelheim International Gmbh | New use of flibanserin |
| WO2008074795A1 (en) | 2006-12-20 | 2008-06-26 | Boehringer Ingelheim International Gmbh | Sulfated benzimidazolone derivatives having mixed serotonine receptor affinity |
| EP1955699A1 (en) * | 2007-02-08 | 2008-08-13 | Boehringer Ingelheim Pharma GmbH & Co. KG | Use of flibanserin for the treatment of insomnia |
| CL2008002693A1 (es) | 2007-09-12 | 2009-10-16 | Boehringer Ingelheim Int | Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad |
| EP2090297A1 (en) | 2008-02-13 | 2009-08-19 | Boehringer Ingelheim International GmbH | Formulations of flibanserin |
| CA2686480A1 (en) * | 2008-12-15 | 2010-06-15 | Boehringer Ingelheim International Gmbh | New salts |
| CN104926734B (zh) * | 2015-07-07 | 2017-04-05 | 苏州立新制药有限公司 | 氟班色林的制备方法 |
| WO2017076356A1 (zh) * | 2015-11-05 | 2017-05-11 | 苏州晶云药物科技有限公司 | 氟班色林的新晶型及其制备方法 |
| WO2017128932A1 (zh) * | 2016-01-31 | 2017-08-03 | 孟晓明 | 氟班色林的新晶型及其制备方法及其用途 |
| CN111303043A (zh) * | 2019-04-19 | 2020-06-19 | 武汉万知化工医药有限公司 | 一种氟班色林盐酸盐的制备方法 |
| CN115919860B (zh) | 2022-12-05 | 2023-11-10 | 中国药科大学 | 氟班色林在制备治疗雄激素脱发药物中的用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1251144B (it) * | 1991-07-30 | 1995-05-04 | Boehringer Ingelheim Italia | Derivati del benzimidazolone |
-
2002
- 2002-07-30 AU AU2002331361A patent/AU2002331361B2/en not_active Expired
- 2002-07-30 EP EP02767277A patent/EP1414816B1/en not_active Expired - Lifetime
- 2002-07-30 CN CNB028152263A patent/CN1288147C/zh not_active Expired - Fee Related
- 2002-07-30 NZ NZ530510A patent/NZ530510A/en not_active IP Right Cessation
- 2002-07-30 CA CA002450093A patent/CA2450093C/en not_active Expired - Fee Related
- 2002-07-30 EP EP04026410A patent/EP1518858A1/en not_active Withdrawn
- 2002-07-30 PT PT02767277T patent/PT1414816E/pt unknown
- 2002-07-30 HU HU0401201A patent/HU228666B1/hu unknown
- 2002-07-30 IL IL15915102A patent/IL159151A0/xx unknown
- 2002-07-30 KR KR1020047001497A patent/KR100899297B1/ko not_active Expired - Fee Related
- 2002-07-30 JP JP2003519029A patent/JP3822601B2/ja not_active Expired - Fee Related
- 2002-07-30 DE DE60202958T patent/DE60202958T2/de not_active Expired - Lifetime
- 2002-07-30 RS YUP-78/04A patent/RS50742B/sr unknown
- 2002-07-30 UA UA2004031505A patent/UA76767C2/uk unknown
- 2002-07-30 BR BR0211601-4A patent/BR0211601A/pt not_active Application Discontinuation
- 2002-07-30 SI SI200230104T patent/SI1414816T1/xx unknown
- 2002-07-30 HR HR20040107A patent/HRP20040107B1/xx not_active IP Right Cessation
- 2002-07-30 WO PCT/EP2002/008466 patent/WO2003014079A1/en not_active Ceased
- 2002-07-30 DK DK02767277T patent/DK1414816T3/da active
- 2002-07-30 PL PL364598A patent/PL210224B1/pl unknown
- 2002-07-30 ES ES02767277T patent/ES2237694T3/es not_active Expired - Lifetime
- 2002-07-30 AT AT02767277T patent/ATE288911T1/de active
- 2002-07-30 MX MXPA04000913A patent/MXPA04000913A/es active IP Right Grant
- 2002-07-30 EA EA200400252A patent/EA006400B1/ru not_active IP Right Cessation
- 2002-07-31 MY MYPI20022876A patent/MY127294A/en unknown
- 2002-08-02 AR ARP020102942A patent/AR036208A1/es not_active Application Discontinuation
-
2003
- 2003-12-02 IL IL159151A patent/IL159151A/en active IP Right Grant
-
2004
- 2004-02-25 CO CO04016766A patent/CO5560572A2/es unknown
-
2010
- 2010-07-15 AR ARP100102577A patent/AR077416A2/es unknown
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