|
ATE538794T1
(de)
|
1999-01-13 |
2012-01-15 |
Bayer Healthcare Llc |
Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer
|
|
US8124630B2
(en)
|
1999-01-13 |
2012-02-28 |
Bayer Healthcare Llc |
ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
JP2004536845A
(ja)
*
|
2001-07-11 |
2004-12-09 |
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド |
サイトカイン媒介疾患の治療方法
|
|
WO2003055482A1
(en)
*
|
2001-12-21 |
2003-07-10 |
Novo Nordisk A/S |
Amide derivatives as gk activators
|
|
MXPA04007832A
(es)
|
2002-02-11 |
2005-09-08 |
Bayer Pharmaceuticals Corp |
Aril-ureas con actividad inhibitoria de angiogenesis.
|
|
ATE386030T1
(de)
|
2002-02-25 |
2008-03-15 |
Boehringer Ingelheim Pharma |
1,4-disubstituierte benzokondensierte cycloalkyl- harnstoffverbindungen zur behandlung von zytokinvermittelten erkrankungen
|
|
BR0312023A
(pt)
*
|
2002-06-27 |
2005-03-22 |
Novo Nordisk As |
Composto, composto ativador da glicose cinase, método para evitar a hipoglicemia, uso de um composto, e, composição farmacêutica
|
|
US7202257B2
(en)
|
2003-12-24 |
2007-04-10 |
Deciphera Pharmaceuticals, Llc |
Anti-inflammatory medicaments
|
|
CA2511970C
(en)
*
|
2003-01-14 |
2012-06-26 |
Cytokinetics, Inc. |
Urea derivatives useful in the treatment of heart failure
|
|
US7557129B2
(en)
|
2003-02-28 |
2009-07-07 |
Bayer Healthcare Llc |
Cyanopyridine derivatives useful in the treatment of cancer and other disorders
|
|
WO2004113274A2
(en)
|
2003-05-20 |
2004-12-29 |
Bayer Pharmaceuticals Corporation |
Diaryl ureas with kinase inhibiting activity
|
|
WO2004113352A1
(en)
*
|
2003-06-19 |
2004-12-29 |
Amedis Pharmaceuticals Ltd. |
Silylated heterocyclylurea derivatives as cytokine-inhibitors
|
|
EA010485B1
(ru)
|
2003-07-23 |
2008-10-30 |
Байер Фамэсьютиклс Копэрейшн |
Производное n,n'-дифенилмочевины, фармацевтическая композиция (варианты) и способ лечения и предупреждения заболеваний и состояний с его использованием (варианты)
|
|
CA2536293A1
(en)
*
|
2003-08-22 |
2005-03-03 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Methods of treating copd and pulmonary hypertension
|
|
US7749999B2
(en)
*
|
2003-09-11 |
2010-07-06 |
Itherx Pharmaceuticals, Inc. |
Alpha-ketoamides and derivatives thereof
|
|
WO2005063715A1
(en)
*
|
2003-12-18 |
2005-07-14 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Polymorph of birb 796, a p38map kinase inhibitor
|
|
JP4834840B2
(ja)
*
|
2004-01-06 |
2011-12-14 |
ノヴォ ノルディスク アー/エス |
ヘテロアリール尿素およびグルコキナーゼ活性化剤としてのその使用
|
|
WO2005105758A1
(en)
*
|
2004-04-22 |
2005-11-10 |
The Procter & Gamble Company |
Tri-substituted ureas as cytokine inhibitors
|
|
CN101010315A
(zh)
*
|
2004-04-30 |
2007-08-01 |
拜耳制药公司 |
用于治疗癌症的取代的吡唑基脲衍生物
|
|
JP5080970B2
(ja)
|
2004-06-17 |
2012-11-21 |
サイトキネティクス・インコーポレーテッド |
心疾患を治療するための置換尿素誘導体
|
|
PL1778686T3
(pl)
|
2004-08-12 |
2009-04-30 |
Pfizer |
Pochodne triazolopirydynylosulfanylowe jako inhibitory kinazy MAP P38
|
|
EP1824843A2
(en)
|
2004-12-07 |
2007-08-29 |
Locus Pharmaceuticals, Inc. |
Inhibitors of protein kinases
|
|
JP2008523071A
(ja)
|
2004-12-07 |
2008-07-03 |
ルーカス ファーマシューティカルズ, インコーポレイテッド |
Mapキナーゼの尿素インヒビター
|
|
DOP2006000051A
(es)
|
2005-02-24 |
2006-08-31 |
Lilly Co Eli |
Inhibidores de vegf-r2 y métodos
|
|
ES2382815T3
(es)
*
|
2005-07-08 |
2012-06-13 |
Novo Nordisk A/S |
Dicicloalquilcarbamoil ureas como activadores de glucoquinasa
|
|
US7884210B2
(en)
|
2005-07-14 |
2011-02-08 |
Novo Nordisk A/S |
Ureido-thiazole glucokinase activators
|
|
TW200808321A
(en)
|
2005-12-15 |
2008-02-16 |
Cytokinetics Inc |
Certain chemical entities, compositions and methods
|
|
US20070208000A1
(en)
*
|
2005-12-15 |
2007-09-06 |
Morgan Bradley P |
Certain chemical entities, compositions and methods
|
|
US20070197505A1
(en)
*
|
2005-12-15 |
2007-08-23 |
Morgan Bradley P |
Certain chemical entities, compositions and methods
|
|
US7825120B2
(en)
*
|
2005-12-15 |
2010-11-02 |
Cytokinetics, Inc. |
Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas
|
|
EP1959962A2
(en)
|
2005-12-16 |
2008-08-27 |
Cytokinetics, Inc. |
Certain chemical entities, compositions, and methods
|
|
EP1962852B1
(en)
*
|
2005-12-19 |
2017-01-25 |
Cytokinetics, Inc. |
Compounds, compositions and methods
|
|
WO2008084043A1
(en)
*
|
2007-01-09 |
2008-07-17 |
Novo Nordisk A/S |
Urea glucokinase activators
|
|
WO2008084044A1
(en)
|
2007-01-11 |
2008-07-17 |
Novo Nordisk A/S |
Urea glucokinase activators
|
|
RU2353355C2
(ru)
*
|
2007-06-15 |
2009-04-27 |
Государственное образовательное учреждение высшего профессионального образования "КРАСНОЯРСКАЯ ГОСУДАРСТВЕННАЯ МЕДИЦИНСКАЯ АКАДЕМИЯ ФЕДЕРАЛЬНОГО АГЕНТСТВА ПО ЗДРАВООХРАНЕНИЮ И СОЦИАЛЬНОМУ РАЗВИТИЮ" |
Способ коррекции иммунной недостаточности у больных острым деструктивным панкреатитом
|
|
WO2010036316A1
(en)
*
|
2008-09-24 |
2010-04-01 |
Yangbo Feng |
Urea and carbamate compounds and analogs as kinase inhibitors
|
|
GB0818033D0
(en)
|
2008-10-02 |
2008-11-05 |
Respivert Ltd |
Novel compound
|
|
MY159230A
(en)
|
2008-10-02 |
2016-12-30 |
Respivert Ltd |
P38 map kinase inhibitors
|
|
JP5670912B2
(ja)
|
2008-12-11 |
2015-02-18 |
レスピバート・リミテツド |
p38MAPキナーゼ阻害剤
|
|
GB0905955D0
(en)
|
2009-04-06 |
2009-05-20 |
Respivert Ltd |
Novel compounds
|
|
NZ601085A
(en)
*
|
2010-02-01 |
2015-04-24 |
Cancer Rec Tech Ltd |
1-(5-tert-butyl-2-phenyl-2h-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1h-imidazo[4,5-b]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapy
|
|
UA110816C2
(uk)
|
2011-01-30 |
2016-02-25 |
Мейдзі Сейка Фарма Ко., Лтд. |
Місцевий протигрибковий засіб
|
|
EP2578582A1
(en)
|
2011-10-03 |
2013-04-10 |
Respivert Limited |
1-Pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl)ureas as p38 MAP kinase inhibitors
|
|
CN103917536B
(zh)
|
2011-10-03 |
2016-07-06 |
瑞斯比维特有限公司 |
1-吡唑基-3-(4-((2-(苯氨基)嘧啶-4-基)氧基)萘-1-基)脲用作p38 MAP激酶抑制剂
|
|
US8461179B1
(en)
|
2012-06-07 |
2013-06-11 |
Deciphera Pharmaceuticals, Llc |
Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
|
|
WO2014015056A2
(en)
*
|
2012-07-17 |
2014-01-23 |
Washington University |
Anti-mucus drugs and uses therefor
|
|
CN104661661A
(zh)
|
2012-07-30 |
2015-05-27 |
明治制果药业株式会社 |
抗白癣菌症外用液剂
|
|
JP6124892B2
(ja)
|
2012-07-30 |
2017-05-10 |
Meiji Seikaファルマ株式会社 |
抗白癬菌症貼付剤
|
|
GB201214750D0
(en)
|
2012-08-17 |
2012-10-03 |
Respivert Ltd |
Compounds
|
|
EP2890701B1
(en)
|
2012-08-29 |
2017-03-29 |
Respivert Limited |
Kinase inhibitors
|
|
US20150210722A1
(en)
|
2012-08-29 |
2015-07-30 |
Respivert Limited |
Kinase inhibitors
|
|
GB201215357D0
(en)
|
2012-08-29 |
2012-10-10 |
Respivert Ltd |
Compounds
|
|
US20150225373A1
(en)
|
2012-08-29 |
2015-08-13 |
Respivert Limited |
Kinase inhibitors
|
|
EP2970190A1
(en)
|
2013-03-14 |
2016-01-20 |
Respivert Limited |
Kinase inhibitors
|
|
US9771353B2
(en)
|
2013-04-02 |
2017-09-26 |
Topivert Pharma Limited |
Kinase inhibitors based upon N-alkyl pyrazoles
|
|
KR102283876B1
(ko)
|
2013-04-02 |
2021-07-29 |
옥슬러 액퀴지션즈 리미티드 |
키나제 저해제로서 유용한 우레아 유도체
|
|
EP3083604A1
(en)
|
2013-12-20 |
2016-10-26 |
Respivert Limited |
Urea derivatives useful as kinase inhibitors
|
|
ES2677595T3
(es)
|
2014-02-14 |
2018-08-03 |
Respivert Limited |
Compuestos heterocíclicos aromáticos como compuestos antiinflamatorios
|
|
CN106573892B
(zh)
|
2014-08-13 |
2019-10-25 |
明治制果药业株式会社 |
结晶性抗白癣菌药及其制备方法
|
|
MA40774A
(fr)
|
2014-10-01 |
2017-08-08 |
Respivert Ltd |
Dérivés de diaryle-urée en tant qu'inhibiteurs de kinase p38
|
|
CA3015978A1
(en)
|
2016-04-06 |
2017-10-12 |
Topivert Pharma Limited |
Kinase inhibitors
|
|
WO2019071147A1
(en)
|
2017-10-05 |
2019-04-11 |
Fulcrum Therapeutics, Inc. |
INHIBITORS OF KINASE P38 REDUCING EXPRESSION OF DUX4 GENE AND DOWNSTREAM GENES FOR THE TREATMENT OF FSHD
|
|
US10342786B2
(en)
|
2017-10-05 |
2019-07-09 |
Fulcrum Therapeutics, Inc. |
P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
|
|
KR102708177B1
(ko)
|
2018-01-31 |
2024-09-23 |
데시페라 파마슈티칼스, 엘엘씨. |
위장관 기질 종양의 치료를 위한 병용 요법
|
|
IL276398B2
(en)
|
2018-01-31 |
2026-03-01 |
Deciphera Pharmaceuticals Llc |
Combination therapy for mastocytosis
|
|
CN112040945A
(zh)
|
2018-06-12 |
2020-12-04 |
Vtv治疗有限责任公司 |
葡萄糖激酶激活剂与胰岛素或胰岛素类似物组合的治疗用途
|
|
EP3938363A1
(en)
|
2019-03-11 |
2022-01-19 |
Teva Pharmaceuticals International GmbH |
Solid state forms of ripretinib
|
|
LT4013412T
(lt)
|
2019-08-12 |
2026-03-25 |
Deciphera Pharmaceuticals, Llc |
Ripretinibas, skirtas virškinamojo trakto stromos navikų gydymui
|
|
PT4013412T
(pt)
|
2019-08-12 |
2026-03-18 |
Deciphera Pharmaceuticals Llc |
Ripretinib para o tratamento de tumores estromais gastrointestinais
|
|
HRP20231699T1
(hr)
|
2019-12-30 |
2024-05-10 |
Deciphera Pharmaceuticals, Llc |
Formulacije inhibitora amorfne kinaze i postupci njihove primjene
|
|
CN115243681B
(zh)
|
2019-12-30 |
2024-08-16 |
德西费拉制药有限责任公司 |
1-(4-溴-5-(1-乙基-7-(甲氨基)-2-侧氧基-1,2-二氢-1,6-萘啶-3-基)-2-氟苯基)-3-苯基脲的组合物
|
|
US12391658B2
(en)
|
2020-02-18 |
2025-08-19 |
Vtv Therapeutics Llc |
Sulfoxide and sulfone glucokinase activators and methods of use thereof
|
|
US11779572B1
(en)
|
2022-09-02 |
2023-10-10 |
Deciphera Pharmaceuticals, Llc |
Methods of treating gastrointestinal stromal tumors
|