JP2005528374A5 - - Google Patents
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- Publication number
- JP2005528374A5 JP2005528374A5 JP2003581743A JP2003581743A JP2005528374A5 JP 2005528374 A5 JP2005528374 A5 JP 2005528374A5 JP 2003581743 A JP2003581743 A JP 2003581743A JP 2003581743 A JP2003581743 A JP 2003581743A JP 2005528374 A5 JP2005528374 A5 JP 2005528374A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- carbon atoms
- group
- amino
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CN1C(*)=C(*)N(*)C1 Chemical compound CN1C(*)=C(*)N(*)C1 0.000 description 17
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02007699 | 2002-04-05 | ||
| PCT/EP2003/003434 WO2003084503A2 (en) | 2002-04-05 | 2003-04-02 | P38 kinase inhibitors for treating mucus hypersecretion_ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005528374A JP2005528374A (ja) | 2005-09-22 |
| JP2005528374A5 true JP2005528374A5 (https=) | 2006-06-01 |
Family
ID=28685842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003581743A Pending JP2005528374A (ja) | 2002-04-05 | 2003-04-02 | 粘液分泌過多の治療方法 |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1494645A2 (https=) |
| JP (1) | JP2005528374A (https=) |
| KR (1) | KR20040101398A (https=) |
| CN (1) | CN1658834A (https=) |
| AU (1) | AU2003224025A1 (https=) |
| BR (1) | BR0309009A (https=) |
| CA (1) | CA2479520A1 (https=) |
| IL (1) | IL163737A0 (https=) |
| MX (1) | MXPA04009605A (https=) |
| NZ (1) | NZ536278A (https=) |
| PL (1) | PL372963A1 (https=) |
| RU (1) | RU2004132847A (https=) |
| WO (1) | WO2003084503A2 (https=) |
| ZA (1) | ZA200406910B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004101529A1 (ja) * | 2003-05-19 | 2004-11-25 | Ono Pharmaceutical Co., Ltd. | 含窒素複素環化合物およびその医薬用途 |
| US8309562B2 (en) | 2003-07-03 | 2012-11-13 | Myrexis, Inc. | Compounds and therapeutical use thereof |
| US8258145B2 (en) | 2005-01-03 | 2012-09-04 | Myrexis, Inc. | Method of treating brain cancer |
| WO2006137421A1 (ja) * | 2005-06-21 | 2006-12-28 | Kyowa Hakko Kogyo Co., Ltd. | 局所投与剤 |
| FR2903774B1 (fr) * | 2006-07-17 | 2008-09-05 | Renault Sas | Procede de validation d'un diagnostic de fontionnement d'un dispositif. |
| MY159230A (en) | 2008-10-02 | 2016-12-30 | Respivert Ltd | P38 map kinase inhibitors |
| GB0818033D0 (en) | 2008-10-02 | 2008-11-05 | Respivert Ltd | Novel compound |
| JP5670912B2 (ja) | 2008-12-11 | 2015-02-18 | レスピバート・リミテツド | ｐ３８ＭＡＰキナーゼ阻害剤 |
| GB0905955D0 (en) | 2009-04-06 | 2009-05-20 | Respivert Ltd | Novel compounds |
| US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
| WO2019071147A1 (en) | 2017-10-05 | 2019-04-11 | Fulcrum Therapeutics, Inc. | INHIBITORS OF KINASE P38 REDUCING EXPRESSION OF DUX4 GENE AND DOWNSTREAM GENES FOR THE TREATMENT OF FSHD |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184226B1 (en) * | 1998-08-28 | 2001-02-06 | Scios Inc. | Quinazoline derivatives as inhibitors of P-38 α |
| NZ528846A (en) * | 1999-03-12 | 2005-05-27 | Boehringer Ingelheim Pharma | Compounds useful as anti-inflammatory agents |
| JP2003500403A (ja) * | 1999-05-21 | 2003-01-07 | サイオス，インコーポレーテッド | ｐ３８キナーゼのインヒビターとしてのインドール型誘導体 |
| HK1053107A1 (zh) * | 1999-08-19 | 2003-10-10 | Signal Pharmaceuticals, Inc. | 作为jnk抗化剂的pyrazoloanthrone及其衍生物和它们的成份 |
| AU7584500A (en) * | 1999-09-17 | 2001-04-17 | Smithkline Beecham Corporation | Use of csaids in rhinovirus infection |
| EP1317450B1 (en) * | 2000-09-15 | 2006-11-22 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| JP2004511542A (ja) * | 2000-10-19 | 2004-04-15 | スミスクライン・ビーチャム・コーポレイション | 煙の吸入の治療のためのｐ３８阻害剤の使用 |
| MXPA03009361A (es) * | 2001-04-13 | 2004-01-29 | Boehringer Ingelheim Pharma | Compuestos de urea utilies como agentes anti-inflamatorios. |
| TR200401028T2 (tr) * | 2001-11-09 | 2004-11-22 | Scios Inc. | Kistik fibrozun tedavisine yönelik metot |
-
2003
- 2003-04-02 AU AU2003224025A patent/AU2003224025A1/en not_active Abandoned
- 2003-04-02 CN CN038129884A patent/CN1658834A/zh active Pending
- 2003-04-02 BR BR0309009-4A patent/BR0309009A/pt not_active IP Right Cessation
- 2003-04-02 IL IL16373703A patent/IL163737A0/xx unknown
- 2003-04-02 PL PL03372963A patent/PL372963A1/xx not_active Application Discontinuation
- 2003-04-02 WO PCT/EP2003/003434 patent/WO2003084503A2/en not_active Ceased
- 2003-04-02 CA CA002479520A patent/CA2479520A1/en not_active Abandoned
- 2003-04-02 JP JP2003581743A patent/JP2005528374A/ja active Pending
- 2003-04-02 MX MXPA04009605A patent/MXPA04009605A/es unknown
- 2003-04-02 KR KR10-2004-7015891A patent/KR20040101398A/ko not_active Withdrawn
- 2003-04-02 NZ NZ536278A patent/NZ536278A/en unknown
- 2003-04-02 EP EP03720407A patent/EP1494645A2/en not_active Ceased
- 2003-04-02 RU RU2004132847/15A patent/RU2004132847A/ru not_active Application Discontinuation
-
2004
- 2004-08-31 ZA ZA200406910A patent/ZA200406910B/xx unknown
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