|
US6664259B2
(en)
*
|
2000-03-16 |
2003-12-16 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
JP2005503400A
(ja)
*
|
2001-09-13 |
2005-02-03 |
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド |
サイトカイン媒介病の治療方法
|
|
ATE386030T1
(de)
|
2002-02-25 |
2008-03-15 |
Boehringer Ingelheim Pharma |
1,4-disubstituierte benzokondensierte cycloalkyl- harnstoffverbindungen zur behandlung von zytokinvermittelten erkrankungen
|
|
TW200418812A
(en)
*
|
2002-10-29 |
2004-10-01 |
Smithkline Beecham Corp |
IL-8 receptor antagonists
|
|
WO2004080966A1
(ja)
|
2003-03-14 |
2004-09-23 |
Ono Pharmaceutical Co., Ltd. |
含窒素複素環誘導体およびそれらを有効成分とする薬剤
|
|
US7749999B2
(en)
|
2003-09-11 |
2010-07-06 |
Itherx Pharmaceuticals, Inc. |
Alpha-ketoamides and derivatives thereof
|
|
EP1790637B1
(en)
|
2004-09-13 |
2014-01-29 |
Ono Pharmaceutical Co., Ltd. |
Derivatives of N-4-piperidyl urea and medicaments containing them as active ingredient
|
|
WO2006035760A1
(ja)
*
|
2004-09-27 |
2006-04-06 |
Santen Pharmaceutical Co., Ltd. |
皮膚疾患治療剤
|
|
WO2006035759A1
(ja)
*
|
2004-09-27 |
2006-04-06 |
Santen Pharmaceutical Co., Ltd. |
呼吸器疾患治療剤
|
|
WO2006043518A1
(ja)
*
|
2004-10-18 |
2006-04-27 |
Santen Pharmaceutical Co., Ltd. |
神経疾患治療剤
|
|
EP1824843A2
(en)
|
2004-12-07 |
2007-08-29 |
Locus Pharmaceuticals, Inc. |
Inhibitors of protein kinases
|
|
JP2008523071A
(ja)
|
2004-12-07 |
2008-07-03 |
ルーカス ファーマシューティカルズ， インコーポレイテッド |
Ｍａｐキナーゼの尿素インヒビター
|
|
KR20090008217A
(ko)
*
|
2006-03-10 |
2009-01-21 |
오노 야꾸힝 고교 가부시키가이샤 |
질소 함유 복소환 유도체 및 이들을 유효 성분으로 하는 약제
|
|
TWI417095B
(zh)
|
2006-03-15 |
2013-12-01 |
Janssen Pharmaceuticals Inc |
１，４-二取代之３-氰基-吡啶酮衍生物及其作為ｍＧｌｕＲ２-受體之正向異位性調節劑之用途
|
|
AR060562A1
(es)
*
|
2006-04-21 |
2008-06-25 |
Smithkline Beecham Corp |
Compuestos heterociclicos como antagonistas del receptor il-8. procesos de obtencion y composiciones farmaceuticas.
|
|
US8097626B2
(en)
*
|
2006-04-21 |
2012-01-17 |
Glaxosmithkline Llc |
IL-8 receptor antagonists
|
|
AR061571A1
(es)
*
|
2006-06-23 |
2008-09-03 |
Smithkline Beecham Corp |
Compuesto sal del acido toluenosulfonico de 4-{[6-cloro-3-({[(2- cloro-3-fluorofenil) amino]carbonil} amino)- 2- hidroxifenil]sulfonil] -1- piperazinacarbxilato de 1.1-dimetiletilo, composicion farmaceutica que lo comprende su uso para la fabricacion de un medicamento combinacion farmaceutica con un
|
|
TW200845978A
(en)
|
2007-03-07 |
2008-12-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
|
|
TW200900065A
(en)
|
2007-03-07 |
2009-01-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
|
|
PL2203439T3
(pl)
|
2007-09-14 |
2011-06-30 |
Addex Pharmaceuticals Sa |
1',3'-dipodstawione-4-fenylo-3,4,5,6-tetrahydro-2H, 1'H-[1, 4']bipirydynylo-2'-ketony
|
|
EP2259680A4
(en)
*
|
2008-03-04 |
2012-01-25 |
Merck Sharp & Dohme |
SOLUBLE EPOXYHYDROLASE INHIBITORS, COMPOSITIONS COMPRISING SUCH COMPOUNDS AND TREATMENT METHODS THEREWITH
|
|
JP5547194B2
(ja)
|
2008-09-02 |
2014-07-09 |
ジャンセン ファーマシューティカルズ， インコーポレイテッド． |
代謝型グルタミン酸受容体の調節因子としての３−アザビシクロ［３．１．０］ヘキシル誘導体
|
|
WO2010060589A1
(en)
|
2008-11-28 |
2010-06-03 |
Ortho-Mcneil-Janssen Pharmaceuticals, Inc. |
Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors
|
|
CN102439008B
(zh)
|
2009-05-12 |
2015-04-29 |
杨森制药有限公司 |
1,2,4-三唑并[4,3-a]吡啶衍生物及其用于治疗或预防神经和精神病症的用途
|
|
MY153913A
(en)
|
2009-05-12 |
2015-04-15 |
Janssen Pharmaceuticals Inc |
7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
|
|
MY153912A
(en)
|
2009-05-12 |
2015-04-15 |
Janssen Pharmaceuticals Inc |
1, 2, 4,-triazolo[4,3-a[pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
|
|
AR076601A1
(es)
|
2009-05-21 |
2011-06-22 |
Chlorion Pharma Inc |
Pirimidinas como agentes terapeuticos
|
|
JP5865898B2
(ja)
|
2010-04-30 |
2016-02-17 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションＩｎｄｉａｎａ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ |
リネゾリドを調製するためのプロセス
|
|
GB201009731D0
(en)
*
|
2010-06-10 |
2010-07-21 |
Pulmagen Therapeutics Inflamma |
Kinase inhibitors
|
|
EP2661435B1
(en)
|
2010-11-08 |
2015-08-19 |
Janssen Pharmaceuticals, Inc. |
1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
|
|
CN103261195B
(zh)
|
2010-11-08 |
2015-09-02 |
杨森制药公司 |
1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途
|
|
PL2649069T3
(pl)
|
2010-11-08 |
2016-01-29 |
Janssen Pharmaceuticals Inc |
Pochodne 1,2,4-triazolo[4,3-a]pirydyny i ich zastosowanie jako dodatnich allosterycznych modulatorów receptorów mGluR2
|
|
US9550737B2
(en)
|
2012-06-11 |
2017-01-24 |
Ucb Biopharma Sprl |
TNF -α modulating benzimidazoles
|
|
JO3368B1
(ar)
|
2013-06-04 |
2019-03-13 |
Janssen Pharmaceutica Nv |
مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
|
|
JO3367B1
(ar)
|
2013-09-06 |
2019-03-13 |
Janssen Pharmaceutica Nv |
مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
|
|
KR20220049612A
(ko)
|
2014-01-21 |
2022-04-21 |
얀센 파마슈티카 엔.브이. |
대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도
|
|
HUE053734T2
(hu)
|
2014-01-21 |
2021-07-28 |
Janssen Pharmaceutica Nv |
2-es altípusú metabotróp glutamáterg receptor pozitív allosztérikus modulátorait tartalmazó kombinációk és alkalmazásuk
|
|
GB201510758D0
(en)
|
2015-06-18 |
2015-08-05 |
Ucb Biopharma Sprl |
Novel TNFa structure for use in therapy
|
|
GB201621907D0
(en)
|
2016-12-21 |
2017-02-01 |
Ucb Biopharma Sprl And Sanofi |
Antibody epitope
|
|
MX2020003242A
(es)
|
2017-09-22 |
2020-09-18 |
Jubilant Epipad LLC |
Compuestos heterociclicos como inhibidores de pad.
|
|
AU2018352142B2
(en)
|
2017-10-18 |
2022-08-25 |
Jubilant Epipad LLC |
Imidazo-pyridine compounds as PAD inhibitors
|
|
KR20200085836A
(ko)
|
2017-11-06 |
2020-07-15 |
주빌런트 프로델 엘엘씨 |
Pd1/pd-l1 활성화 억제제로서의 피리미딘 유도체
|
|
BR112020010322A2
(pt)
|
2017-11-24 |
2020-11-17 |
Jubilant Episcribe Llc |
composto da fórmula i; composto da fórmula ia; composto da fórmula ib; processo de preparação de compostos da fórmula i; composição farmacêutica; método para o tratamento e/ou prevenção de várias doenças; uso dos compostos; método para o tratamento de câncer; e método para o tratamento e/ou prevenção de uma afecção mediada por prmt5 ou um distúrbio proliferativo ou câncer
|
|
SG11202008950PA
(en)
|
2018-03-13 |
2020-10-29 |
Jubilant Prodel LLC |
Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation
|
|
CN116354891B
(zh)
*
|
2022-11-07 |
2025-01-07 |
河南省锐达医药科技有限公司 |
一种萘基苯醚类化合物、其制备方法及应用
|