JP2004532028A5 - - Google Patents
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- JP2004532028A5 JP2004532028A5 JP2002582274A JP2002582274A JP2004532028A5 JP 2004532028 A5 JP2004532028 A5 JP 2004532028A5 JP 2002582274 A JP2002582274 A JP 2002582274A JP 2002582274 A JP2002582274 A JP 2002582274A JP 2004532028 A5 JP2004532028 A5 JP 2004532028A5
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- Prior art keywords
- fusion protein
- agt
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- protein
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- Prior art date
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- XWNJMSJGJFSGRY-UHFFFAOYSA-N 2-(benzylamino)-3,7-dihydropurin-6-one Chemical compound N1C=2N=CNC=2C(=O)N=C1NCC1=CC=CC=C1 XWNJMSJGJFSGRY-UHFFFAOYSA-N 0.000 claims description 4
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- OHDRQQURAXLVGJ-HLVWOLMTSA-N azane;(2e)-3-ethyl-2-[(e)-(3-ethyl-6-sulfo-1,3-benzothiazol-2-ylidene)hydrazinylidene]-1,3-benzothiazole-6-sulfonic acid Chemical compound [NH4+].[NH4+].S/1C2=CC(S([O-])(=O)=O)=CC=C2N(CC)C\1=N/N=C1/SC2=CC(S([O-])(=O)=O)=CC=C2N1CC OHDRQQURAXLVGJ-HLVWOLMTSA-N 0.000 description 2
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- 101000966481 Mus musculus Dihydrofolate reductase Proteins 0.000 description 1
- ZRKWMRDKSOPRRS-UHFFFAOYSA-N N-Methyl-N-nitrosourea Chemical compound O=NN(C)C(N)=O ZRKWMRDKSOPRRS-UHFFFAOYSA-N 0.000 description 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
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- BPEGJWRSRHCHSN-UHFFFAOYSA-N Temozolomide Chemical compound O=C1N(C)N=NC2=C(C(N)=O)N=CN21 BPEGJWRSRHCHSN-UHFFFAOYSA-N 0.000 description 1
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- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
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- BPHPUYQFMNQIOC-NXRLNHOXSA-N isopropyl beta-D-thiogalactopyranoside Chemical compound CC(C)S[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O BPHPUYQFMNQIOC-NXRLNHOXSA-N 0.000 description 1
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- CPTBDICYNRMXFX-UHFFFAOYSA-N procarbazine Chemical compound CNNCC1=CC=C(C(=O)NC(C)C)C=C1 CPTBDICYNRMXFX-UHFFFAOYSA-N 0.000 description 1
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28276601P | 2001-04-10 | 2001-04-10 | |
| PCT/GB2002/001636 WO2002083937A2 (en) | 2001-04-10 | 2002-04-05 | Methods using o6-alkylguanine-dna alkyltransferases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007328757A Division JP4226053B2 (ja) | 2001-04-10 | 2007-12-20 | Ｏ６−アルキルグアニン−ｄｎａアルキルトランスフェラーゼ（ａｇｔ）の使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004532028A JP2004532028A (ja) | 2004-10-21 |
| JP2004532028A5 true JP2004532028A5 (enExample) | 2008-10-02 |
| JP4195815B2 JP4195815B2 (ja) | 2008-12-17 |
Family
ID=23083030
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002582274A Expired - Lifetime JP4195815B2 (ja) | 2001-04-10 | 2002-04-05 | Ｏ６−アルキルグアニン−ｄｎａアルキルトランスフェラーゼ（ａｇｔ）の使用方法 |
| JP2007328757A Expired - Fee Related JP4226053B2 (ja) | 2001-04-10 | 2007-12-20 | Ｏ６−アルキルグアニン−ｄｎａアルキルトランスフェラーゼ（ａｇｔ）の使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007328757A Expired - Fee Related JP4226053B2 (ja) | 2001-04-10 | 2007-12-20 | Ｏ６−アルキルグアニン−ｄｎａアルキルトランスフェラーゼ（ａｇｔ）の使用方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7939284B2 (enExample) |
| EP (4) | EP1410023B1 (enExample) |
| JP (2) | JP4195815B2 (enExample) |
| KR (1) | KR20040039194A (enExample) |
| CN (2) | CN1975422B (enExample) |
| AT (3) | ATE331220T1 (enExample) |
| AU (1) | AU2002251257B2 (enExample) |
| CA (1) | CA2443570A1 (enExample) |
| DE (3) | DE60237792D1 (enExample) |
| DK (1) | DK1410023T3 (enExample) |
| IL (1) | IL157880A0 (enExample) |
| NZ (3) | NZ540410A (enExample) |
| WO (1) | WO2002083937A2 (enExample) |
| ZA (1) | ZA200307442B (enExample) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1717496A (zh) * | 2002-10-03 | 2006-01-04 | 洛桑生态综合技术联合公司 | 用o6－烷基鸟嘌呤－dna烷基转移酶标记蛋白 |
| WO2004031405A1 (en) * | 2002-10-03 | 2004-04-15 | Ecole Polytechnique Federale De Lausanne (Epfl) | Substrates for o6-alkylguanine-dna alkyltransferase |
| CA2514564A1 (en) | 2003-01-31 | 2005-07-26 | Promega Corporation | Covalent tethering of functional groups to proteins |
| US7429472B2 (en) | 2003-01-31 | 2008-09-30 | Promega Corporation | Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule |
| AU2004242249A1 (en) * | 2003-05-23 | 2004-12-02 | Epfl-Ecole Polytechnique Federale De Lausanne | Methods for protein labeling based on acyl carrier protein |
| WO2005085470A1 (en) * | 2004-03-02 | 2005-09-15 | Epfl Ecole Polytechnique Federale De Lausanne | Specific substrates for o6- alkylguanine-dna alkyltransferase |
| JP2007525988A (ja) | 2004-03-02 | 2007-09-13 | ウペエフエル・エコル・ポリテクニック・フェデラル・ドゥ・ローザンヌ | Ｏ６−アルキルグアニン−ｄｎａアルキルトランスフェラーゼの突然変異体 |
| US7425436B2 (en) | 2004-07-30 | 2008-09-16 | Promega Corporation | Covalent tethering of functional groups to proteins and substrates therefor |
| US7825096B2 (en) | 2004-09-08 | 2010-11-02 | The United States Of America As Represented By The Department Of Health And Human Services | O6-alkylguanine-DNA alkyltransferase inactivators and beta-glucuronidase cleavable prodrugs |
| US7273714B2 (en) * | 2005-03-11 | 2007-09-25 | Vion Pharmaceuticals, Inc. | Alkylguanyltransferase assays |
| WO2006114409A1 (en) * | 2005-04-27 | 2006-11-02 | Covalys Biosciences Ag | Pyrimidines reacting with o6-alkylguanine-dna alkyltransferase |
| FR2890174B1 (fr) | 2005-08-30 | 2009-04-24 | Cis Bio Internat Sa | Procede pour la mise en evidence d'un processus biologique par mesure d'un fret |
| FR2890446B1 (fr) | 2005-09-05 | 2008-04-18 | Cis Bio Internat Sa | Methode de detection d'interaction intracellulaire entre bio-molecules |
| US9110054B2 (en) | 2006-06-30 | 2015-08-18 | Discoverx Corporation | Detectable nucleic acid tag |
| US8420367B2 (en) | 2006-10-30 | 2013-04-16 | Promega Corporation | Polynucleotides encoding mutant hydrolase proteins with enhanced kinetics and functional expression |
| US7897737B2 (en) | 2006-12-05 | 2011-03-01 | Lasergen, Inc. | 3′-OH unblocked, nucleotides and nucleosides, base modified with photocleavable, terminating groups and methods for their use in DNA sequencing |
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