JP2004525957A5 - - Google Patents
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- Publication number
- JP2004525957A5 JP2004525957A5 JP2002580924A JP2002580924A JP2004525957A5 JP 2004525957 A5 JP2004525957 A5 JP 2004525957A5 JP 2002580924 A JP2002580924 A JP 2002580924A JP 2002580924 A JP2002580924 A JP 2002580924A JP 2004525957 A5 JP2004525957 A5 JP 2004525957A5
- Authority
- JP
- Japan
- Prior art keywords
- sodium
- product
- pharmaceutical composition
- sodium caprate
- csf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FIWQZURFGYXCEO-UHFFFAOYSA-M sodium;decanoate Chemical compound [Na+].CCCCCCCCCC([O-])=O FIWQZURFGYXCEO-UHFFFAOYSA-M 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 229960005480 sodium caprylate Drugs 0.000 claims 3
- BYKRNSHANADUFY-UHFFFAOYSA-M sodium octanoate Chemical compound [Na+].CCCCCCCC([O-])=O BYKRNSHANADUFY-UHFFFAOYSA-M 0.000 claims 3
- 102000004127 Cytokines Human genes 0.000 claims 2
- 108090000695 Cytokines Proteins 0.000 claims 2
- 208000004235 neutropenia Diseases 0.000 claims 2
- 208000019838 Blood disease Diseases 0.000 claims 1
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 claims 1
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 claims 1
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 claims 1
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 1
- 102000003812 Interleukin-15 Human genes 0.000 claims 1
- 108090000172 Interleukin-15 Proteins 0.000 claims 1
- 102000000588 Interleukin-2 Human genes 0.000 claims 1
- 108010002350 Interleukin-2 Proteins 0.000 claims 1
- 208000002720 Malnutrition Diseases 0.000 claims 1
- 239000012190 activator Substances 0.000 claims 1
- 210000001185 bone marrow Anatomy 0.000 claims 1
- 238000010322 bone marrow transplantation Methods 0.000 claims 1
- 230000001332 colony forming effect Effects 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 208000014951 hematologic disease Diseases 0.000 claims 1
- 208000018706 hematopoietic system disease Diseases 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 235000018343 nutrient deficiency Nutrition 0.000 claims 1
- 238000001959 radiotherapy Methods 0.000 claims 1
- 230000001629 suppression Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28445801P | 2001-04-18 | 2001-04-18 | |
| US60/284,458 | 2001-04-18 | ||
| PCT/CA2002/000535 WO2002083120A2 (en) | 2001-04-18 | 2002-04-18 | Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009272679A Division JP5657879B2 (ja) | 2001-04-18 | 2009-11-30 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004525957A JP2004525957A (ja) | 2004-08-26 |
| JP2004525957A5 true JP2004525957A5 (enExample) | 2009-08-20 |
| JP5026655B2 JP5026655B2 (ja) | 2012-09-12 |
Family
ID=23090294
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002580924A Expired - Lifetime JP5026655B2 (ja) | 2001-04-18 | 2002-04-18 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
| JP2009272679A Expired - Lifetime JP5657879B2 (ja) | 2001-04-18 | 2009-11-30 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
| JP2014165557A Expired - Lifetime JP6420089B2 (ja) | 2001-04-18 | 2014-08-15 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009272679A Expired - Lifetime JP5657879B2 (ja) | 2001-04-18 | 2009-11-30 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
| JP2014165557A Expired - Lifetime JP6420089B2 (ja) | 2001-04-18 | 2014-08-15 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US7745488B2 (enExample) |
| EP (2) | EP1385498B1 (enExample) |
| JP (3) | JP5026655B2 (enExample) |
| KR (1) | KR20030096323A (enExample) |
| CN (1) | CN1633286A (enExample) |
| AP (1) | AP1740A (enExample) |
| AU (2) | AU2002308456B2 (enExample) |
| BG (1) | BG66418B1 (enExample) |
| BR (1) | BR0208984A (enExample) |
| CA (2) | CA2444463C (enExample) |
| CY (1) | CY1107081T1 (enExample) |
| CZ (1) | CZ305273B6 (enExample) |
| DE (1) | DE60223670T2 (enExample) |
| DK (2) | DK1385498T3 (enExample) |
| EA (1) | EA007322B1 (enExample) |
| EE (1) | EE200300510A (enExample) |
| ES (2) | ES2295397T3 (enExample) |
| HU (1) | HUP0303817A3 (enExample) |
| IL (3) | IL158322A0 (enExample) |
| MX (1) | MXPA03009436A (enExample) |
| NO (1) | NO335105B1 (enExample) |
| NZ (2) | NZ541140A (enExample) |
| OA (1) | OA12506A (enExample) |
| PL (2) | PL223348B1 (enExample) |
| PT (2) | PT1900364E (enExample) |
| SI (1) | SI1385498T1 (enExample) |
| SK (1) | SK12772003A3 (enExample) |
| TN (1) | TNSN03089A1 (enExample) |
| WO (1) | WO2002083120A2 (enExample) |
| ZA (1) | ZA200307778B (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2444463C (en) | 2001-04-18 | 2012-03-20 | Prometic Biosciences Inc. | Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors |
| DE04708802T1 (de) * | 2003-02-07 | 2006-06-22 | Prometic Biosciences Inc., Montreal | Fettsäuren mittlerer kettenlänge, glyceride und analoga als stimulatoren der erythropoiese |
| DE602004006137T3 (de) | 2003-07-25 | 2012-01-19 | Prometic Biosciences Inc. | Herstellung von metallsalzen von fettsäuren mit mittlerer kettenlänge |
| US20070219131A1 (en) * | 2004-04-15 | 2007-09-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
| US20050232981A1 (en) * | 2004-04-15 | 2005-10-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
| CA2578993A1 (en) * | 2004-09-03 | 2006-03-09 | Prometic Biosciences Inc. | Substituted purinyl derivatives with immunomodulator and chemoprotective activity and use alone or with medium-chain length fatty acids or glycerides |
| NZ554176A (en) | 2004-10-01 | 2010-04-30 | Prometic Biosciences Inc | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
| US8071580B2 (en) * | 2004-10-01 | 2011-12-06 | Prometic Biosciences Inc. | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
| EP1858912B1 (en) * | 2005-02-28 | 2012-04-11 | Alphabeta AB | Compounds for reducing aggregation of amyloid beta-peptide |
| CA2687446A1 (en) * | 2006-05-17 | 2007-11-29 | Cognate Therapeutics, Inc. | Isolation and purification of hematopoietic stem cells from post-liposuction lipoaspirates |
| US8324277B2 (en) | 2007-08-01 | 2012-12-04 | University of Pittsburgh—of the Commonwealth System of Higher Education | Nitrated-fatty acids modulation of type II diabetes |
| PT2299998T (pt) | 2007-11-02 | 2018-04-02 | Prometic Pharma Smt Ltd | Acidos gordos e glicerídeos de cadeia média como agentes nefroprotetores |
| EP2231166B1 (en) * | 2007-12-19 | 2013-03-20 | ProMetic BioSciences Inc. | Medium-chain length fatty acids, salts and triglycerides in combination with gemcitabine for treatment of pancreatic cancer |
| CN102083787A (zh) | 2008-05-01 | 2011-06-01 | 康普雷克萨公司 | 乙烯基取代的脂肪酸 |
| US20140024713A1 (en) | 2008-06-19 | 2014-01-23 | University Of Utah Research Foundation | Use of nitrated lipids for treatment of side effects of toxic medical therapies |
| WO2009155439A2 (en) | 2008-06-19 | 2009-12-23 | University Of Utah Research Foundation | Use of nitrated lipids for treatment of side effects of toxic medical therapies |
| HRP20170929T1 (hr) | 2008-09-17 | 2017-09-22 | Chiasma Inc. | Farmaceutski pripravci i odgovarajući postupci za isporuku |
| EP2165713B1 (en) * | 2008-09-19 | 2012-11-14 | Nestec S.A. | Whey and thymus function |
| JP2013500966A (ja) | 2009-07-31 | 2013-01-10 | ユニバーシティー オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション | 抗炎症剤としての脂肪酸 |
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| EP2394636B1 (en) * | 2010-05-28 | 2014-03-19 | Novagali Pharma S.A. | Method for treating retinal conditions using an intraocular tamponade |
| WO2013028501A1 (en) | 2011-08-19 | 2013-02-28 | The University Of Utah Research Foundation | Combination therapy with nitrated lipids and inhibitors of the renin-angiotensin-aldosterone system |
| TWI572352B (zh) * | 2012-03-01 | 2017-03-01 | 波麥堤克藥學Smt有限公司 | 用於製備具中鏈長度之脂肪酸的三酸甘油酯之方法 |
| LT2846809T (lt) | 2012-05-09 | 2021-01-25 | Cantex Pharmaceuticals, Inc. | Mielosupresijos gydymas |
| RU2646823C2 (ru) | 2013-08-19 | 2018-03-07 | Энзикем Лайфсайенсиз Корпорейшн | Композиция для предотвращения или лечения ревматоидного артрита, содержащая в качестве активного ингредиента моноацетилдиглицерид |
| KR20180015297A (ko) * | 2014-05-15 | 2018-02-12 | 주식회사 엔지켐생명과학 | 백혈구 감소증 및 혈소판 감소증에 대한 치료 방법 |
| AU2016215350B2 (en) | 2015-02-03 | 2021-11-25 | Amryt Endo, Inc. | Method of treating diseases |
| US10052346B2 (en) | 2015-02-17 | 2018-08-21 | Cantex Pharmaceuticals, Inc. | Treatment of myelodysplastic syndromes with 2-O and,or 3-O desulfated heparinoids |
| BR112018000254A2 (pt) | 2015-07-07 | 2018-09-04 | H Lundbeck As | inibidores de pde9 com cadeia principal de imidazotriazinona e cadeia principal de imidazopirazinona para o tratamento de doenças periféricas |
| IL258476B2 (en) | 2015-10-02 | 2023-04-01 | Complexa Inc | Prevention, treatment and reversal of disease using therapeutically effective amounts of activated fatty acids |
| US9808438B2 (en) | 2015-11-09 | 2017-11-07 | Enzychem Lifesciences Corporation | Method for treating mucositis |
| US10588974B2 (en) | 2016-04-22 | 2020-03-17 | Receptor Holdings, Inc. | Fast-acting plant-based medicinal compounds and nutritional supplements |
| TWI749016B (zh) | 2016-06-08 | 2021-12-11 | 董宇紅 | 具有奇數碳的脂類化合物及其作為醫藥組合物或者營養補充劑的用途 |
| EA201892396A1 (ru) | 2016-12-02 | 2019-04-30 | Ресептор Лайф Сайенсиз, Инк. | Быстродействующие растительные лекарственные соединения и биологически активные добавки |
| CN107382710B (zh) * | 2017-08-19 | 2020-11-06 | 中国铁道科学研究院集团有限公司铁道建筑研究所 | 一种接枝抗氧剂分子的多元醇 |
| BR112020004023A2 (pt) * | 2017-09-12 | 2020-09-08 | Sunregen Healthcare Ag | uso de um composto e composição farmacêutica ou suplemento nutricional |
| BR112020006841A2 (pt) * | 2017-10-05 | 2020-10-06 | Receptor Holdings, Inc. | formulações de canabinoide sintéticas e à base de planta com ação prolongada e início rápido |
| AU2018345812A1 (en) * | 2017-10-05 | 2020-05-14 | Spoke Sciences, Inc. | Herbal compositions with improved bioavailability |
| KR102054401B1 (ko) * | 2018-03-26 | 2019-12-10 | 주식회사 엔지켐생명과학 | 1,2-디아실글리세롤 화합물, 그 제조방법 및 이를 유효성분으로 함유하는 면역조절제 |
| HUE065709T2 (hu) | 2018-05-25 | 2024-06-28 | Cardurion Pharmaceuticals Inc | 6-[(3S,4S)-4-metil-1-(pirimidin-2-ilmetil)pirrolidin-3-il]-3-tetrahidropirán-4-il-7H-imidazo[1,5-a] pirazin-8-on vegyület monohidrát és kristályos formái |
| MA53501A (fr) | 2018-08-31 | 2021-07-07 | Imara Inc | Inhibiteurs de pde9 pour le traitement de la drépanocytose |
| CA3112073A1 (en) | 2018-10-11 | 2020-04-16 | Basf As | Aromatic compounds and pharmaceutical uses thereof |
| US12303487B2 (en) | 2018-11-19 | 2025-05-20 | Spoke Sciences, Inc. | N-acylated fatty amino acids to reduce absorption variability in cannabinoid based compositions |
| WO2021085144A1 (ja) * | 2019-10-31 | 2021-05-06 | 日本ゼオン株式会社 | 電気化学素子用機能層およびその製造方法、電気化学素子用機能層付きセパレータおよびその製造方法、並びに電気化学素子およびその製造方法 |
| US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
| WO2023067501A1 (en) * | 2021-10-18 | 2023-04-27 | Enzychem Lifesciences Corporation | Compositions and methods for treating mucositis |
| US20250270471A1 (en) * | 2022-04-21 | 2025-08-28 | Merck Sharp & Dohme Llc | Process for preparing agglomerated crystalline medium-chain fatty acid sodium salts |
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| CA2444463C (en) | 2001-04-18 | 2012-03-20 | Prometic Biosciences Inc. | Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors |
| US20040052836A1 (en) | 2002-09-13 | 2004-03-18 | Li Luk Chiu | Pharmaceutical compositions containing at least one stable liposphere having an improved shelf life |
| DE04708802T1 (de) | 2003-02-07 | 2006-06-22 | Prometic Biosciences Inc., Montreal | Fettsäuren mittlerer kettenlänge, glyceride und analoga als stimulatoren der erythropoiese |
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| CA2578993A1 (en) * | 2004-09-03 | 2006-03-09 | Prometic Biosciences Inc. | Substituted purinyl derivatives with immunomodulator and chemoprotective activity and use alone or with medium-chain length fatty acids or glycerides |
| US8071580B2 (en) | 2004-10-01 | 2011-12-06 | Prometic Biosciences Inc. | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
-
2002
- 2002-04-18 CA CA2444463A patent/CA2444463C/en not_active Expired - Lifetime
- 2002-04-18 BR BR0208984-0A patent/BR0208984A/pt not_active Application Discontinuation
- 2002-04-18 NZ NZ541140A patent/NZ541140A/en not_active IP Right Cessation
- 2002-04-18 MX MXPA03009436A patent/MXPA03009436A/es active IP Right Grant
- 2002-04-18 HU HU0303817A patent/HUP0303817A3/hu unknown
- 2002-04-18 PL PL366435A patent/PL223348B1/pl unknown
- 2002-04-18 US US10/475,266 patent/US7745488B2/en not_active Expired - Lifetime
- 2002-04-18 EP EP02761857A patent/EP1385498B1/en not_active Expired - Lifetime
- 2002-04-18 EP EP07116425.5A patent/EP1900364B1/en not_active Expired - Lifetime
- 2002-04-18 IL IL15832202A patent/IL158322A0/xx active IP Right Grant
- 2002-04-18 WO PCT/CA2002/000535 patent/WO2002083120A2/en not_active Ceased
- 2002-04-18 EA EA200301131A patent/EA007322B1/ru not_active IP Right Cessation
- 2002-04-18 OA OA1200300273A patent/OA12506A/en unknown
- 2002-04-18 AU AU2002308456A patent/AU2002308456B2/en not_active Expired
- 2002-04-18 DK DK02761857T patent/DK1385498T3/da active
- 2002-04-18 NZ NZ528690A patent/NZ528690A/en not_active IP Right Cessation
- 2002-04-18 CN CNA028094263A patent/CN1633286A/zh active Pending
- 2002-04-18 DE DE60223670T patent/DE60223670T2/de not_active Expired - Lifetime
- 2002-04-18 SK SK1277-2003A patent/SK12772003A3/sk unknown
- 2002-04-18 SI SI200230655T patent/SI1385498T1/sl unknown
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2003
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